Yi-Chen Hsieh

Research output

Research output per year 2005 2021

• 738 Citations
• 16 h-Index
• 50 Article
• 1 Chapter

Research output per year

Research output per year

Search results

• 2021

  Interactive Effects of a Combination of the HDAC3 and HDAC9 Genes with Diabetes Mellitus on the Risk of Ischemic Stroke

  Chiou, H. Y., Bai, C. H., Lien, L. M., Hu, C. J., Jeng, J. S., Tang, S. C., Lin, H. J. & Hsieh, Y. C., Mar 2021, In: Thrombosis and Haemostasis. 121, 3

  Research output: Contribution to journal › Article › peer-review

  • Diabetes Mellitus
  • Stroke
  • Genes
  • Atherosclerosis
  • Single Nucleotide Polymorphism

• The effect of de-escalation of P2Y₁₂ receptor inhibitor therapy after acute myocardial infarction in patients undergoing percutaneous coronary intervention: A nationwide cohort study

  Yeh, J. S., Hsu, C. Y., Huang, C. Y., Chen, W. T., Hsieh, Y. C. & Chien, L. N., Jan 2021, In: PLoS ONE. 16, 1 1, e0246029.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • cohort studies
  • myocardial infarction
  • Percutaneous Coronary Intervention
  • Ticagrelor
  • Aspirin
• 2020

  Altered Insulin Receptor Substrate 1 Phosphorylation in Blood Neuron-Derived Extracellular Vesicles From Patients With Parkinson’s Disease

  Chou, S. Y., Chan, L., Chung, C. C., Chiu, J. Y., Hsieh, Y. C. & Hong, C. T., Dec 3 2020, In: Frontiers in Cell and Developmental Biology. 8, 564641.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Insulin Receptor Substrate Proteins
  • Extracellular Vesicles
  • Parkinson Disease
  • Phosphorylation
  • Neurons
  1 Citation (Scopus)

• Association between Anemia and Dementia-A Nationwide, Population-Based Cohort Study in Taiwan

  Hong, C-T., Hsieh, Y-C., Liu, H-Y., Chiou, H-Y. & Chien, L-N., Mar 17 2020, In: Current Alzheimer Research. 17, 2, p. 196-204 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Taiwan
  • Anemia
  • Dementia
  • Cohort Studies
  • Population
  4 Citations (Scopus)

• Association between anemia and stroke in females: A nationwide, population-based cohort study in taiwan

  Sui, Y., Hong, C. T., Chien, L. N., Liu, H. Y., Chiou, H. Y. & Hsieh, Y. C., Oct 2 2020, In: International journal of environmental research and public health. 17, 20, p. 1-13 13 p., 7440.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Taiwan
  • Anemia
  • Cohort Studies
  • Stroke
  • Population

• Comparison between ticagrelor versus clopidogrel in long term outcomes of Taiwanese diabetic subjects with acute coronary syndrome undergoing successful revascularization: From TSOC ACS-DM registry

  Wang, C-A., Hsieh, Y-C., Huang, C-Y., Liu, J-C., Hsieh, M-H., Lin, Y-K. & Yeh, J-S., May 2020, In: Medicine. 99, 19, p. e19969

  Research output: Contribution to journal › Article › peer-review

  • Ticagrelor
  • Clopidogrel
  • Acute Coronary Syndrome
  • Registries
  • Hospitalization

• Comparison of the TIMI, GRACE, PAMI and CADILLAC risk scores for prediction of longterm cardiovascular outcomes in Taiwanese diabetic patients with ST-segment elevation myocardial infarction: From the registry of the Taiwan Society of Cardiology

  Kao, Y. T., Hsieh, Y. C., Hsu, C. Y., Huang, C. Y., Hsieh, M. H., Lin, Y. K. & Yeh, J. S., Jan 1 2020, In: PLoS ONE. 15, 2, p. e0229186 e0229186.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cardiology
  • Abciximab
  • myocardial infarction
  • ST Elevation Myocardial Infarction
  • Taiwan
  3 Citations (Scopus)

• Dicoumarol suppresses HMGA2-mediated oncogenic capacities and inhibits cell proliferation by inducing apoptosis in colon cancer

  Chen, C. H., Hsieh, Y. C., Yang, P. M., Liu, Y. R. & Cho, E. C., 2020, In: Biochemical and Biophysical Research Communications.

  Research output: Contribution to journal › Article › peer-review

  • Dicumarol
  • Cell proliferation
  • High Mobility Group Proteins
  • Oxidative stress
  • Colonic Neoplasms
  2 Citations (Scopus)

• Exosomal TAR DNA-binding protein-43 and neurofilaments in plasma of amyotrophic lateral sclerosis patients: A longitudinal follow-up study

  Chen, P. C., Wu, D., Hu, C. J., Chen, H. Y., Hsieh, Y. C. & Huang, C. C., Nov 15 2020, In: Journal of the Neurological Sciences. 418, p. 117070 117070.

  Research output: Contribution to journal › Article › peer-review

  • DNA-Binding Proteins
  • Intermediate Filaments
  • Amyotrophic Lateral Sclerosis
  • Light
  • Biomarkers
  3 Citations (Scopus)

• Hydrolyzed chicken extract (Probeptigen®) on cognitive function in healthy middle-aged people: A randomized double-blind trial

  Wu, D., Yang, C. C., Chen, K. Y., Lin, Y. C., Wu, P. J., Hsieh, P. H., Nakao, Y., Ow, M. Y. L., Hsieh, Y. C. & Hu, C. J., May 10 2020, In: Nutrients. 12, 5, 1362.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • cognition
  • Middle Aged
  • Chickens
  • Short-Term Memory
  • Cognition
  1 Citation (Scopus)

• Hyperglycemia-related FAS gene and hsa-let-7b-5p as markers of poor outcomes for ischaemic stroke

  Chi, N-F., Chiou, H-Y., Chou, S-Y., Hu, C-J., Chen, K-Y., Chang, C-F. & Hsieh, Y-C., Aug 2020, In: European Journal of Neurology. 27, 8, p. 1647-1655 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Hyperglycemia
  • Stroke
  • MicroRNAs
  • Genes
  • Exosomes
  2 Citations (Scopus)

• Tamoxifen for amyotrophic lateral sclerosis: A randomized double-blind clinical trial

  Chen, P. C., Hsieh, Y. C., Huang, C. C. & Hu, C. J., May 29 2020, In: Medicine. 99, 22, p. e20423

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amyotrophic Lateral Sclerosis
  • Tamoxifen
  • Clinical Trials
  • DNA-Binding Proteins
  • Vital Capacity
  6 Citations (Scopus)
• 2019

  NO₂ functionalized coumarin derivatives suppress cancer progression and facilitate apoptotic cell death in KRAS mutant colon cancer

  Lin, M. H., Wang, J. S., Hsieh, Y. C., Zheng, J. H. & Cho, E. C., Aug 25 2019, In: Chemico-Biological Interactions. 309, 108708.

  Research output: Contribution to journal › Article › peer-review

  • Cell death
  • Coumarins
  • coumarin
  • Cells
  • Colonic Neoplasms
  9 Citations (Scopus)

• Prevalence and clinical characteristics of stroke patients with p.R544C NOTCH3 mutation in Taiwan

  Tang, S. C., Chen, Y. R., Chi, N. F., Chen, C. H., Cheng, Y. W., Hsieh, F. I., Hsieh, Y. C., Yeh, H. L., Sung, P. S., Hu, C. J., Chern, C. M., Lin, H. J., Lien, L. M., Peng, G. S., Chiou, H. Y. & Jeng, J. S., Jan 1 2019, In: Annals of Clinical and Translational Neurology. 6, 1, p. 121-128 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Taiwan
  • Stroke
  • Mutation
  • Cerebral Hemorrhage
  • CADASIL
  8 Citations (Scopus)
• 2018

  Cerebral Motor Functional Connectivity at the Acute Stage: An Outcome Predictor of Ischemic Stroke

  Chi, N. F., Ku, H. L., Chen, D. Y. T., Tseng, Y. C., Chen, C. J., Lin, Y. C., Hsieh, Y. C., Chan, L., Chiou, H. Y., Hsu, C. Y. & Hu, C. J., Dec 1 2018, In: Scientific Reports. 8, 1, 16803.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Motor Cortex
  • Multivariate Analysis
  • Magnetic Resonance Imaging
  • Odds Ratio
  5 Citations (Scopus)

• Effectiveness and Safety of Standard- and Low-Dose Rivaroxaban in Asians With Atrial Fibrillation

  Lin, Y. C., Chien, S. C., Hsieh, Y. C., Shih, C. M., Lin, F. Y., Tsao, N. W., Chen, C. W., Kao, Y. T., Chiang, K. H., Chen, W. T., Chien, L. N. & Huang, C. Y., Jul 31 2018, In: Journal of the American College of Cardiology. 72, 5, p. 477-485 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Rivaroxaban
  • Atrial Fibrillation
  • Safety
  • Hemorrhage
  • Myocardial Infarction
  19 Citations (Scopus)

• Serum amyloid A1 in combination with integrin αVβ3 increases glioblastoma cells mobility and progression

  Lin, C. Y., Yang, S. T., Shen, S. C., Hsieh, Y. C., Hsu, F. T., Chen, C. Y., Chiang, Y. H., Chuang, J. Y., Chen, K. Y., Hsu, T. I., Leong, W. C., Su, Y. K., Lo, W. L., Yeh, Y. S., Patria, Y. N., Shih, H. M., Chang, C. C. & Chou, S. Y., May 1 2018, In: Molecular Oncology. 12, 5, p. 756-771 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Glioblastoma
  • Amyloid
  • Integrins
  • Serum
  • Glioma
  15 Citations (Scopus)
• 2017

  A polygenic risk score for breast cancer risk in a Taiwanese population

  Hsieh, Y. C., Tu, S. H., Su, C. T., Cho, E. C., Wu, C. H., Hsieh, M. C., Lin, S. Y., Liu, Y. R., Hung, C. S. & Chiou, H. Y., May 1 2017, In: Breast Cancer Research and Treatment. 163, 1, p. 131-138 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Breast Neoplasms
  • Population
  • Single Nucleotide Polymorphism
  • Genome-Wide Association Study
  • Area Under Curve
  18 Citations (Scopus)

• A rapid and quantitative method to detect human circulating tumor cells in a preclinical animal model

  Tu, S. H., Hsieh, Y. C., Huang, L. C., Lin, C. Y., Hsu, K. W., Hsieh, W. S., Chi, W. M. & Lee, C. H., Jun 23 2017, In: BMC Cancer. 17, 1, 440.

  Research output: Contribution to journal › Article › peer-review

  • Circulating Neoplastic Cells
  • Animal Models
  • Neoplasms
  • Cell Count
  • Neoplasm Metastasis
  9 Citations (Scopus)

• Associations of estradiol levels and genetic polymorphisms of inflammatory genes with the risk of ischemic stroke

  Hsieh, Y. C., Hsieh, F. I., Chen, Y. R., Hu, C. J., Jeng, J. S., Tang, S. C., Chi, N. F., Lin, H. J., Lien, L. M., Peng, G. S. & Chiou, H. Y., Mar 28 2017, In: Journal of Biomedical Science. 24, 1, 25.

  Research output: Contribution to journal › Article › peer-review

  • Polymorphism
  • Genetic Polymorphisms
  • Genes
  • Estradiol
  • Stroke
  3 Citations (Scopus)

• Comparison of admission random glucose, fasting glucose, and glycated hemoglobin in predicting the neurological outcome of acute ischemic stroke: A retrospective study

  Sung, J. Y., Chen, C. I., Hsieh, Y. C., Chen, Y. R., Wu, H. C., Chan, L., Hu, C. J., Hu, H. H., Chiou, H. Y. & Chi, N. F., 2017, In: PeerJ. 2017, 2, e2948.

  Research output: Contribution to journal › Article › peer-review

  • glycohemoglobin
  • retrospective studies
  • stroke
  • Glycated Hemoglobin A
  • fasting
  10 Citations (Scopus)

• Diagnostic accuracy of standardised qualitative sensory test in the detection of lumbar lateral stenosis involving the L5 nerve root

  Lin, J. H., Hsieh, Y. C., Chen, Y. C., Wang, Y., Chen, C. C. & Chiang, Y. H., Dec 1 2017, In: Scientific Reports. 7, 1, 10598.

  Research output: Contribution to journal › Article › peer-review

  • Pathologic Constriction
  • Spinal Nerves
  • Neurosurgeons
  • Vibration
  • Diagnostic Errors
  6 Citations (Scopus)

• Early vertebroplasty associated with a lower risk of mortality and respiratory failure in aged patients with painful vertebral compression fractures: A population-based cohort study in Taiwan

  Lin, J. H., Chien, L. N., Tsai, W. L., Chen, L. Y., Chiang, Y. H. & Hsieh, Y. C., 2017, In: Spine Journal.

  Research output: Contribution to journal › Article › peer-review

  • Vertebroplasty
  • Compression Fractures
  • Taiwan
  • Respiratory Insufficiency
  • Cohort Studies
  8 Citations (Scopus)

• MSH2 rs2303425 Polymorphism is Associated with Early-Onset Breast Cancer in Taiwan

  Hsieh, Y. C., Cho, E. C., Tu, S. H., Wu, C. H., Hung, C. S., Hsieh, M-C., Su, C. T., Liu, Y-R., Lee, C. H., Ho, Y. S. & Chiou, H. Y., Feb 1 2017, In: Annals of Surgical Oncology. 24, 2, p. 603-610 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Taiwan
  • Breast Neoplasms
  • DNA Mismatch Repair
  • Single Nucleotide Polymorphism
  • Luciferases
  8 Citations (Scopus)
• 2016

  Comparative Brain and Central Nervous System Tumor Incidence and Survival between the United States and Taiwan Based on Population-Based Registry

  Chien, L-N., Gittleman, H., Ostrom, Q. T., Hung, K-S., Sloan, A. E., Hsieh, Y-C., Kruchko, C., Rogers, L. R., Wang, Y-F. G., Chiou, H-Y. & Barnholtz-Sloan, J. S., 2016, In: Frontiers in Public Health. 4, p. 151

  Research output: Contribution to journal › Article › peer-review

  • Central Nervous System Neoplasms
  • Taiwan
  • Registries
  • Nervous System Neoplasms
  • Survival

• Effectiveness of essence of chicken in improving cognitive function in young people under work-related stress: A randomized double-blind trial

  Chan, L., Wang, H. M., Chen, K. Y., Lin, Y-C., Wu, P. J., Hsieh, W. L., Chen, Y. R., Liu, C. P., Tsai, H. Y., Chen, Y. R., Chang, H. H., Hsieh, Y-C. & Hu, C-J., 2016, In: Medicine (United States). 95, 19, e3640.

  Research output: Contribution to journal › Article › peer-review

  • Occupational Stress
  • Chickens
  • Cognition
  • Blood Urea Nitrogen
  • Alanine Transaminase
  6 Citations (Scopus)

• GWAS for executive function and processing speed suggests involvement of the CADM2 gene

  Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., Chibnik, L. B., Liu, Y., Vitart, V., Kirin, M., Petrovic, K., Polasek, O., Zgaga, L., Fawns-Ritchie, C., Hoffmann, P., Karjalainen, J. & 106 others, Lahti, J., Llewellyn, D. J., Schmidt, C. O., Mather, K. A., Chouraki, V., Sun, Q., Resnick, S. M., Rose, L. M., Oldmeadow, C., Stewart, M., Smith, B. H., Gudnason, V., Yang, Q., Mirza, S. S., Jukema, J. W., DeJager, P. L., Harris, T. B., Liewald, D. C., Amin, N., Coker, L. H., Stegle, O., Lopez, O. L., Schmidt, R., Teumer, A., Ford, I., Karbalai, N., Becker, J. T., Jonsdottir, M. K., Au, R., Fehrmann, R. S. N., Herms, S., Nalls, M., Zhao, W., Turner, S. T., Yaffe, K., Lohman, K., Van Swieten, J. C., Kardia, S. L. R., Knopman, D. S., Meeks, W. M., Heiss, G., Holliday, E. G., Schofield, P. W., Tanaka, T., Stott, D. J., Wang, J., Ridker, P., Gow, A. J., Pattie, A., Starr, J. M., Hocking, L. J., Armstrong, N. J., McLachlan, S., Shulman, J. M., Pilling, L. C., Eiriksdottir, G., Scott, R. J., Kochan, N. A., Palotie, A., Hsieh, Y. C., Eriksson, J. G., Penman, A., Gottesman, R. F., Oostra, B. A., Yu, L., DeStefano, A. L., Beiser, A., Garcia, M., Rotter, J. I., Nöthen, M. M., Hofman, A., Slagboom, P. E., Westendorp, R. G. J., Buckley, B. M., Wolf, P. A., Uitterlinden, A. G., Psaty, B. M., Grabe, H. J., Bandinelli, S., Chasman, D. I., Grodstein, F., Räikkönen, K., Lambert, J. C., Porteous, D. J., Price, J. F., Sachdev, P. S., Ferrucci, L., Attia, J. R., Rudan, I., Hayward, C., Wright, A. F., Wilson, J. F., Cichon, S., Franke, L., Schmidt, H., Ding, J., De Craen, A. J. M., Fornage, M., Bennett, D. A., Deary, I. J., Ikram, M. A., Launer, L. J., Fitzpatrick, A. L., Seshadri, S., Van Duijn, C. M. & Mosley, T. H., Feb 1 2016, In: Molecular Psychiatry. 21, 2, p. 189-197 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Adhesion Molecules
  • Genome-Wide Association Study
  • Executive Function
  • Electronic Data Processing
  • Genes
  70 Citations (Scopus)

• Reoperation rates of anterior cervical discectomy and fusion versus posterior laminoplasty for multilevel cervical degenerative diseases: a population-based cohort study in Taiwan

  Lin, J. H., Chien, L. N., Tsai, W. L., Chen, L. Y., Hsieh, Y. C. & Chiang, Y. H., Dec 1 2016, In: Spine Journal. 16, 12, p. 1428-1436 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Laminoplasty
  • Diskectomy
  • Taiwan
  • Reoperation
  • Cohort Studies
  6 Citations (Scopus)
• 2015

  Genome-wide studies of verbal declarative memory in nondemented older people: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

  Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, 2015, In: Biological Psychiatry. 77, 8, p. 749-763 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Epidemiology
  • Memory
  • Genome
  • Heart
  • Ubiquitin
  43 Citations (Scopus)

• Risk factors correlated with risk of insulin resistance using homeostasis model assessment in adolescents in Taiwan

  Lin, S-Y., Su, C-T., Hsieh, Y-C., Li, Y. L., Chen, Y. R., Cheng, S. Y., Hu, C. M., Chen, Y-H., Hsieh, F-I. & Chiou, H-Y., Mar 4 2015, In: Asia-Pacific Journal of Public Health. 27, 2, p. NP476-NP484

  Research output: Contribution to journal › Article › peer-review

  • Taiwan
  • Insulin Resistance
  • Homeostasis
  • Odds Ratio
  • Confidence Intervals
  3 Citations (Scopus)

• RRM2B-mediated regulation of mitochondrial activity and inflammation under oxidative stress

  Cho, E. C., Kuo, M. L., Cheng, J. H., Cheng, Y. C., Hsieh, Y. C., Liu, Y. R., Hsieh, R. H. & Yen, Y., 2015, In: Mediators of Inflammation. 2015, 287345.

  Research output: Contribution to journal › Article › peer-review

  • Ribonucleotide Reductases
  • Oxidative Stress
  • Mitochondrial Genes
  • Inflammation
  • DNA Damage
  11 Citations (Scopus)
• 2014

  A germline missense mutation in COQ6 is associated with susceptibility to familial schwannomatosis

  Zhang, K., Lin, J. W., Wang, J., Wu, X., Gao, H., Hsieh, Y. C., Hwu, P., Liu, Y. R., Su, L., Chiou, H. Y., Wang, D., Yuan, Y. C., Whang-Peng, J., Chiu, W. T. & Yen, Y., Oct 1 2014, In: Genetics in medicine : official journal of the American College of Medical Genetics. 16, 10, p. 787-792 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Schwannomatosis
  • Germ-Line Mutation
  • Missense Mutation
  • Coenzyme Q10 Deficiency
  • ubiquinone 6
  12 Citations (Scopus)

• CHRNA9 polymorphisms and smoking exposure synergize to increase the risk of breast cancer in Taiwan

  Hsieh, Y. C., Lee, C. H., Tu, S. H., Wu, C. H., Hung, C. S., Hsieh, M. C., Chuang, C. W., Ho, Y. S. & Chiou, H. Y., Nov 1 2014, In: Carcinogenesis. 35, 11, p. 2520-2525 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Taiwan
  • Smoking
  • Single Nucleotide Polymorphism
  • Breast Neoplasms
  • Cholinergic Receptors
  8 Citations (Scopus)

• Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients

  Cho, E. C., Kuo, M. L., Liu, X., Yang, L., Hsieh, Y. C., Wang, J., Cheng, Y. & Yen, Y., 2014, In: Oncotarget. 5, 13, p. 4834-4844 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ribonucleotide Reductases
  • Survival
  • DNA Replication
  • Neoplasms
  • Tumor Biomarkers
  28 Citations (Scopus)
• 2012

  Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: A one year prospective study in Taiwan

  Hsieh, Y. C., Seshadri, S., Chung, W. T., Hsieh, F. I., Hsu, Y. H., Lin, H. J., Tseng, H. P., Lien, L. M., Bai, C. H., Hu, C. J., Jeng, J. S., Tang, S. C., Chen, C. I., Yu, C. C. & Chiou, H. Y., 2012, In: Journal of Biomedical Science. 19, 1, 1.

  Research output: Contribution to journal › Article › peer-review

  • Polymorphism
  • Chromosomes
  • Taiwan
  • Nucleotides
  • Stroke
  27 Citations (Scopus)

• Epistasis Analysis for Estrogen Metabolic and Signaling Pathway Genes on Young Ischemic Stroke Patients

  Hsieh, Y. C., Jeng, J. S., Lin, H. J., Hu, C. J., Yu, C. C., Lien, L. M., Peng, G. S., Chen, C. I. C. I., Tang, S. C., Chi, N. F., Tseng, H. P., Chern, C. M., Hsieh, F. I. F. I., Bai, C. H., Chen, Y. R., Chiou, H. Y., Jeng, J. S., Tang, S. C., Yeh, S. J., Tsai, L. K. & 63 others, Kong, S., Lien, L. M., Chiu, H. C., Chen, W. H., Bai, C. H., Huang, T. H., Lau, C. I., Wu, Y. Y., Yuan, R. Y., Hu, C. J., Sheu, J. J., Yu, J. M., Ho, C. S., Chen, C. I., Sung, J. Y., Weng, H. Y., Han, Y. H., Huang, C. P., Chung, W. T., Ke, D. S., Lin, H. J., Chang, C. Y., Yeh, P. S., Lin, K. C., Cheng, T. J., Chou, C. H., Yang, C. M., Peng, G. S., Lin, J. C., Hsu, Y. D., Denq, J. C., Lee, J. T., Hsu, C. H., Lin, C. C., Yen, C. H., Cheng, C. A., Sung, Y. F., Chen, Y. L., Lien, M. T., Chou, C. H., Liu, C. C., Yang, F. C., Wu, Y. C., Tso, A. C., Lai, Y. H., Chiang, C. I., Tsai, C. K., Liu, M. T., Lin, Y. C., Hsu, Y. C., Chen, C. H., Sung, P. S., Chern, C. M., Hu, H. H., Wong, W. J., Luk, Y. O., Hsu, L. C., Chung, C. P., Tseng, H. P., Liu, C. H., Lin, C. L., Lin, H. C. & Hu, C. J., Oct 24 2012, In: PLoS One. 7, 10, e47773.

  Research output: Contribution to journal › Article › peer-review

  • catechol
  • Metabolic Networks and Pathways
  • catechol O-methyltransferase
  • Guaiacol
  • epistasis
  8 Citations (Scopus)
• 2011

  Arsenic exposure and cerebrovascular disease

  Chiou, H. Y. & Hsieh, Y. C., Jan 1 2011, Health Hazards of Arsenic Poisoning Environmental: From Epidemic to Pandemic. World Scientific Publishing Co., p. 123-134 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Association of heme oxygenase-1 GT-repeat polymorphism with blood pressure phenotypes and its relevance to future cardiovascular mortality risk: An observation based on arsenic-exposed individuals

  Wu, M. M., Chiou, H. Y., Chen, C. L., Hsu, L. I., Lien, L. M., Wang, C. H., Hsieh, Y. C., Wang, Y. H., Hsueh, Y. M., Lee, T. C., Cheng, W. F. & Chen, C. J., Dec 2011, In: Atherosclerosis. 219, 2, p. 704-708 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Arsenic
  • Heme Oxygenase-1
  • Observation
  • Blood Pressure
  • Phenotype
  20 Citations (Scopus)

• Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes

  Hsieh, Y-C., Lien, L-M., Chung, W. T., Hsieh, F-I., Hsieh, P. F., Wu, M. M., Tseng, H. P., Chiou, H-Y. & Chen, C. J., Aug 2011, In: Environmental Research. 111, 6, p. 804-810 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolism
  • Polymorphism
  • Carotid Artery Diseases
  • Arsenic
  • polymorphism
  50 Citations (Scopus)
• 2010

  Association of blood active matrix metalloproteinase-3 with carotid plaque score from a community population in Taiwan

  Lien, L. M., Hsieh, Y. C., Bai, C. H., Chen, W-H., Chiu, H. C., Hsieh, F. I., Shyu, K-G., Chiou, H. Y. & Hsu, C-Y., Oct 2010, In: Atherosclerosis. 212, 2, p. 595-600 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Matrix Metalloproteinase 3
  • Taiwan
  • Population
  • Matrix Metalloproteinases
  • Matrix Metalloproteinase 1
  16 Citations (Scopus)

• Association of estrogen receptor ± genotypes/ haplotypes with carotid intima-media thickness in taiwanese women

  Wu, M. M., Hsieh, Y. C., Lien, L. M., Chen, W. H., Bai, C. H., Chiu, H. C., Chen, H. H., Chung, W. T., Lee, Y. C., Hsu, C. Y., Lin, H. W. & Chiou, H. Y., Jun 2010, In: Angiology. 61, 3, p. 275-282 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Carotid Intima-Media Thickness
  • Haplotypes
  • Estrogen Receptors
  • Genotype
  • Single Nucleotide Polymorphism
  8 Citations (Scopus)

• Early menarche and ischemic stroke risk among postmenopausal women

  Hsieh, Y. C., Hwang, L. C., Hsieh, F. I., Lien, L. M., Lin, H. J., Hu, C. J., Tseng, H. P., Bai, C. H. & Chiou, H. Y., Mar 2010, In: International Journal of Gerontology. 4, 1, p. 16-22 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Menarche
  • Stroke
  • Estrogens
  • Diabetes Mellitus
  • Menopause
  8 Citations (Scopus)

• GT-repeat polymorphism in the heme oxygenase-1 gene promoter and the risk of carotid atherosclerosis related to arsenic exposure

  Wu, M. M., Chiou, H. Y., Lee, T. C., Chen, C. L., Hsu, L. I., Wang, Y. H., Huang, W. L., Hsieh, Y. C., Yang, T. Y., Lee, C. Y., Yip, P. K., Wang, C. H., Hsueh, Y. M. & Chen, C. J., 2010, In: Journal of Biomedical Science. 17, 1, 70.

  Research output: Contribution to journal › Article › peer-review

  • Polymorphism
  • Carotid Artery Diseases
  • Arsenic
  • Heme Oxygenase-1
  • Genes
  26 Citations (Scopus)

• GT-repeat polymorphism in the heme oxygenase-1 gene promoter is associated with cardiovascular mortality risk in an arsenic-exposed population in northeastern Taiwan

  Wu, M. M., Chiou, H. Y., Chen, C. L., Wang, Y. H., Hsieh, Y. C., Lien, L. M., Lee, T. C. & Chen, C. J., Nov 1 2010, In: Toxicology and Applied Pharmacology. 248, 3, p. 226-233 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Polymorphism
  • Arsenic
  • Heme Oxygenase-1
  • Taiwan
  • Genes
  28 Citations (Scopus)
• 2009

  A significant decrease in blood pressure through a family-based nutrition health education programme among community residents in Taiwan

  Hsieh, Y. C., Hung, C. T., Lien, L. M., Bai, C. H., Chen, W. H., Yeh, C. Y., Chen, Y. H., Hsieh, F. I., Chiu, H. C., Chiou, H. Y. & Hsu, C. Y., Apr 2009, In: Public Health Nutrition. 12, 4, p. 570-577 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Health Education
  • Taiwan
  • Blood Pressure
  • Antihypertensive Agents
  • Stroke
  20 Citations (Scopus)

• Significant synergistic effect of peroxisome proliferator-activated receptor γ C-2821T and diabetes on the risk of ischemic stroke

  Hsieh, F-I., Lo, W. C., Lin, H-J., Hsieh, Y-C., Lien, L-M., Bai, C-H., Tseng, H. P. & Chiou, H-Y., Nov 2009, In: Diabetes Care. 32, 11, p. 2033-2035 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Peroxisome Proliferator-Activated Receptors
  • Stroke
  • Genetic Polymorphisms
  • Alleles
  • Hypertension
  2 Citations (Scopus)
• 2008

  Risk of carotid atherosclerosis associated with genetic polymorphisms of apolipoprotein E and inflammatory genes among arsenic exposed residents in Taiwan

  Hsieh, Y. C., Hsieh, F. I., Lien, L. M., Chou, Y. L., Chiou, H. Y. & Chen, C. J., Feb 15 2008, In: Toxicology and Applied Pharmacology. 227, 1, p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Polymorphism
  • Carotid Artery Diseases
  • Arsenic
  • Apolipoproteins E
  • Genetic Polymorphisms
  31 Citations (Scopus)

• Risk of erectile dysfunction induced by arsenic exposure through well water consumption in Taiwan

  Hsieh, F. I., Huang, Y-S., Hsieh, Y. C., Lo, H. C., Su, C. T., Hsu, H. S., Chiou, H. Y. & Chen, C. J., Apr 2008, In: Environmental Health Perspectives. 116, 4, p. 532-536 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Arsenic
  • well water
  • Erectile Dysfunction
  • water consumption
  • Taiwan
  55 Citations (Scopus)
• 2007

  Effects of arsenic exposure and genetic polymorphisms of p53, glutathione S-transferase M1, T1, and P1 on the risk of carotid atherosclerosis in Taiwan

  Wang, Y-H., Wu, M. M., Hong, C. T., Lien, L-M., Hsieh, Y-C., Tseng, H. P., Chang, S. F., Su, C. L., Chiou, H-Y. & Chen, C. J., Jun 2007, In: Atherosclerosis. 192, 2, p. 305-312 8 p.

  Research output: Contribution to journal › Article › peer-review

  • glutathione S-transferase T1
  • glutathione S-transferase M1
  • Carotid Artery Diseases
  • Arsenic
  • Genetic Polymorphisms
  48 Citations (Scopus)
• 2006

  Effect of plasma homocysteine level and urinary monomethylarsonic acid on the risk of arsenic-associated carotid atherosclerosis

  Wu, M. M., Chiou, H. Y., Hsueh, Y. M., Hong, C. T., Su, C. L., Chang, S. F., Huang, W. L., Wang, H. T., Wang, Y. H., Hsieh, Y. C. & Chen, C. J., Oct 1 2006, In: Toxicology and Applied Pharmacology. 216, 1, p. 168-175 8 p.

  Research output: Contribution to journal › Article › peer-review

  • monomethylarsonic acid
  • Carotid Artery Diseases
  • Arsenic
  • Homocysteine
  • Plasmas
  64 Citations (Scopus)