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Research Output 1995 2019

  • 1314 Citations
  • 21 h-Index
  • 72 Article
  • 2 Patent
  • 1 Comment/debate
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Article
2011
23 Citations (Scopus)

Gastrodia elata prevents huntingtin aggregations through activation of the adenosine A 2A receptor and ubiquitin proteasome system

Huang, C. L., Yang, J. M., Wang, K. C., Lee, Y. C., Lin, Y. L., Yang, Y. C. & Huang, N. K., Oct 31 2011, In : Journal of Ethnopharmacology. 138, 1, p. 162-168 7 p.

Research output: Contribution to journalArticle

Gastrodia
Adenosine A2A Receptors
Proteasome Endopeptidase Complex
Ubiquitin
Cyclic AMP-Dependent Protein Kinases
31 Citations (Scopus)

The neuroprotective effects of an extract of Gastrodia elata

Tsai, C. F., Huang, C. L., Lin, Y. L., Lee, Y. C., Yang, Y. C. & Huang, N. K., Oct 31 2011, In : Journal of Ethnopharmacology. 138, 1, p. 119-125 7 p.

Research output: Contribution to journalArticle

Gastrodia
Neuroprotective Agents
Response Elements
Cyclic AMP Response Element-Binding Protein
Phosphorylation
2010
6 Citations (Scopus)

The roles of the thioredoxin system and peroxiredoxins in 1-methyl-4-phenyl-pyridinium ion-induced cytotoxicity in rat pheochromocytoma cells

Chen, V. T. K., Huang, C. L., Lee, Y. C., Liao, W. C. & Huang, N. K., Sep 2010, In : Toxicology in Vitro. 24, 6, p. 1577-1583 7 p.

Research output: Contribution to journalArticle

1-Methyl-4-phenylpyridinium
Peroxiredoxins
Thioredoxins
PC12 Cells
Pheochromocytoma
13 Citations (Scopus)

Translational up-regulation of Aurora-A in EGFR-overexpressed cancer

Lai, C. H., Tseng, J. T., Lee, Y. C., Chen, Y. J., Lee, J. C., Lin, B. W., Huang, T. C., Liu, Y. W., Leu, T. H., Liu, Y. W., Chen, Y. P., Chang, W. C. & Hung, L. Y., Jun 2010, In : Journal of Cellular and Molecular Medicine. 14, 6 B, p. 1520-1531 12 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Up-Regulation
Epidermal Growth Factor
Neoplasms
Exons
2009
21 Citations (Scopus)

Ligusticum chuanxiong as a potential neuroprotectant for preventing serum deprivation-induced apoptosis in rat pheochromocytoma cells: Functional roles of mitogen-activated protein kinases

Lin, Y. L., Wang, G. J., Huang, C. L., Lee, Y. C., Liao, W. C., Lai, W. L., Lin, Y. J. & Huang, N. K., Apr 21 2009, In : Journal of Ethnopharmacology. 122, 3, p. 417-423 7 p.

Research output: Contribution to journalArticle

Ligusticum
Pheochromocytoma
Neuroprotective Agents
Mitogen-Activated Protein Kinases
Apoptosis
5 Citations (Scopus)

Mechanisms of Panax ginseng in preventing rat pheochromocytoma cells from apoptosis

Lin, Y. L., Huang, C. L., Lee, Y. C., Liao, W. C., Lai, W. L., Lin, Y. J. & Huang, N. K., Aug 17 2009, In : Journal of Ethnopharmacology. 125, 1, p. 10-15 6 p.

Research output: Contribution to journalArticle

Panax
Pheochromocytoma
Apoptosis
Cyclic AMP-Dependent Protein Kinases
PC12 Cells
2008
31 Citations (Scopus)

HDAC1/HDAC3 modulates PPARG2 transcription through the sumoylated CEBPD in hepatic lipogenesis

Lai, P. H., Wang, W. L., Ko, C. Y., Lee, Y. C., Yang, W. M., Shen, T. W., Chang, W. C. & Wang, J. M., Oct 2008, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1783, 10, p. 1803-1814 12 p.

Research output: Contribution to journalArticle

Lipogenesis
Hep G2 Cells
Sumoylation
Liver
CCAAT-Enhancer-Binding Proteins
45 Citations (Scopus)

Modular patterning of structure and function of the striatum by retinoid receptor signaling

Liao, W. L., Tsai, H. C., Wang, H. F., Chang, J., Lu, K. M., Wu, H. L., Lee, Y. C., Tsai, T. F., Takahashi, H., Wagner, M., Ghyselinck, N. B., Chambon, P. & Liu, F. C., May 6 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 18, p. 6765-6770 6 p.

Research output: Contribution to journalArticle

Retinoids
Corpus Striatum
Neurogenesis
Tretinoin
Head Movements
111 Citations (Scopus)

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

Hung, L. Y., Tseng, J. T., Lee, Y. C., Xia, W., Wang, Y. N., Wu, M. L., Chuang, Y. H., Lai, C. H. & Chang, W. C., Aug 2008, In : Nucleic Acids Research. 36, 13, p. 4337-4351 15 p.

Research output: Contribution to journalArticle

STAT5 Transcription Factor
Epidermal Growth Factor Receptor
Epidermal Growth Factor
Gene Expression
Chromosomal Instability
32 Citations (Scopus)

Sumoylation of LAP1 is involved in the HDAC4-mediated repression of COX-2 transcription

Wang, W. L., Lee, Y. C., Yang, W. M., Chang, W. C. & Wang, J. M., 2008, In : Nucleic Acids Research. 36, 19, p. 6066-6079 14 p.

Research output: Contribution to journalArticle

Sumoylation
Epidermal Growth Factor
Adipogenesis
Messenger RNA
Aptitude
2007
18 Citations (Scopus)

Ligusticum chuanxiong prevents rat pheochromocytoma cells from serum deprivation-induced apoptosis through a protein kinase A-dependent pathway

Lin, Y. L., Lee, Y. C., Huang, C. L., Lai, W. L., Lin, Y. R. & Huang, N. K., Feb 12 2007, In : Journal of Ethnopharmacology. 109, 3, p. 428-434 7 p.

Research output: Contribution to journalArticle

Ligusticum
Pheochromocytoma
Cyclic AMP-Dependent Protein Kinases
Apoptosis
Cyclic AMP Response Element-Binding Protein
11 Citations (Scopus)

Methamphetamine downregulates peroxiredoxins in rat pheochromocytoma cells

Chen, H. M., Lee, Y. C., Huang, C. L., Liu, H. K., Liao, W. C., Lai, W. L., Lin, Y. R. & Huang, N. K., Mar 2 2007, In : Biochemical and Biophysical Research Communications. 354, 1, p. 96-101 6 p.

Research output: Contribution to journalArticle

Peroxiredoxins
Methamphetamine
Pheochromocytoma
Thioredoxins
Rats
2006
100 Citations (Scopus)

Formation of porous poly(vinylidene fluoride) membranes with symmetric or asymmetric morphology by immersion precipitation in the water/TEP/PVDF system

Lin, D. J., Chang, H. H., Chen, T. C., Lee, Y. C. & Cheng, L. P., Jul 2006, In : European Polymer Journal. 42, 7, p. 1581-1594 14 p.

Research output: Contribution to journalArticle

vinylidene
submerging
fluorides
phosphates
Phosphates
2005
71 Citations (Scopus)

cAMP-response element-binding protein contributes to suppression of the A2A adenosine receptor promoter by mutant huntingtin with expanded polyglutamine residues

Chiang, M. C., Lee, Y. C., Huang, C. L. & Chern, Y., Apr 8 2005, In : Journal of Biological Chemistry. 280, 14, p. 14331-14340 10 p.

Research output: Contribution to journalArticle

Adenosine A2A Receptors
Cyclic AMP Response Element-Binding Protein
vpr Genes
Genes
Huntington Disease
142 Citations (Scopus)

CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model

Chou, S. Y., Lee, Y. C., Chen, H. M., Chiang, M. C., Lai, H. L., Chang, H. H., Wu, Y. C., Sun, C. N., Chien, C. L., Lin, Y. S., Wang, S. C., Tung, Y. Y., Chang, C. & Chern, Y., Apr 2005, In : Journal of Neurochemistry. 93, 2, p. 310-320 11 p.

Research output: Contribution to journalArticle

Huntington Disease
Transgenic Mice
AMP-Activated Protein Kinases
Heart Ventricles
Brain
2003
46 Citations (Scopus)

Characterization of the rat A2A adenosine receptor gene: A 4.8-kb promoter-proximal DNA fragment confers selective expression in the central nervous system

Lee, Y. C., Chien, C. L., Sun, C. N., Huang, C. L., Huang, N. K., Chiang, M. C., Lai, H. L., Lin, Y. S., Chou, S. Y., Wang, C. K. L., Tai, M. H., Liao, W. L., Lin, T. N., Liu, F. C. & Chern, Y., Oct 2003, In : European Journal of Neuroscience. 18, 7, p. 1786-1796 11 p.

Research output: Contribution to journalArticle

Adenosine A2A Receptors
Transgenes
Central Nervous System
DNA
Genes
11 Citations (Scopus)

Identification of nuclear factor 1 (NF1) as a transcriptional modulator of rat A2A adenosine receptor

Lee, Y. C., Lai, H. L., Sun, C. N., Chien, C. L. & Chern, Y., Mar 17 2003, In : Molecular Brain Research. 111, 1-2, p. 61-73 13 p.

Research output: Contribution to journalArticle

NFI Transcription Factors
Adenosine A2A Receptors
Cell Line
Proteins
5' Flanking Region
1999
20 Citations (Scopus)

The 5' untranslated regions of the rat A(2A) adenosine receptor gene function as negative translational regulators

Lee, Y. C., Chang, C. W., Su, C. W., Lin, T. N., Sun, S. H., Lai, H. L. & Chern, Y., 1999, In : Journal of Neurochemistry. 73, 5, p. 1790-1798 9 p.

Research output: Contribution to journalArticle

Adenosine A2A Receptors
5' Untranslated Regions
Rats
Genes
Firefly Luciferases
1997
25 Citations (Scopus)

Activation of phosphodiesterase IV during desensitization of the A(2A) adenosine receptor-mediated cyclic AMP response in rat pheochromocytoma (PC12) cells

Chang, Y. H., Conti, M., Lee, Y. C., Lai, H. L., Ching, Y. H. & Chern, Y., Sep 1997, In : Journal of Neurochemistry. 69, 3, p. 1300-1309 10 p.

Research output: Contribution to journalArticle

Type 4 Cyclic Nucleotide Phosphodiesterase
Adenosine A2A Receptors
PC12 Cells
Pheochromocytoma
Cyclic AMP
1996
35 Citations (Scopus)

Characterization of the rat A2a adenosine receptor gene

Chu, Y-Y., Tu, K-H., Lee, Y. C., Kuo, Z-J., Lai, H-L. & Chern, Y., Apr 1996, In : DNA and Cell Biology. 15, 4, p. 329-37 9 p.

Research output: Contribution to journalArticle

Purinergic P1 Receptors
PC12 Cells
Genetic Promoter Regions
Genes
5' Flanking Region
10 Citations (Scopus)

Circadian rhythm in the Ca2+-inhibitable adenylyl cyclase activity of the rat striatum

Chern, Y., Lee, E. H. Y., Lai, H. L., Wang, H. L., Lee, Y. C. & Ching, Y. H., May 6 1996, In : FEBS Letters. 385, 3, p. 205-208 4 p.

Research output: Contribution to journalArticle

Circadian Rhythm
Adenylyl Cyclases
Rats
Adenosine
Locomotion
1995
24 Citations (Scopus)
proximal tubules
Primary Cell Culture
glucocorticoids
Glucocorticoids
adenosinetriphosphatase