Yen-Hua Huang

Projects

Projects per year 2010 2010 2011 2012 2013 2014 2015 2017 2018 2019 2020 2022 2023

• 2 Active
• 43 Finished

Projects per year

Search results

• Active

  Targeting Sorafenib-Resistant Hccs: a Novel T Cell Immunotherapeutic Strategy with in Situ Injectable Thermosensitive Peg-Plga- Coated Igf1r/Cd3 Bispecific Antibody and Preclinical 3d Organoid Model (1/3)

  Huang, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Mechanism of Clinical Grade Pcmscs on Immune Modulation and Lung Regeneration in Acute Phase of Ali/Ards( II )

  Huang, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology
• Finished

  探討臨床級胎盤間質幹細胞分泌體於促進半月板前驅細胞之再生能力與免疫調控之研究

  Huang, Y.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討低氧腫瘤細胞外泌體對於腫瘤相關嗜中性球之調控：肝細胞癌模式

  Huang, Y.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討低氧微環境腫瘤外泌體與發炎細胞激素IL-6於B型肝炎病毒誘導肝癌表現多能性幹細胞基因OCT4與TKI抗藥性之調控機制與其臨床意義

  Huang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討急性肺損傷之精準幹細胞治療策略與臨床應用: 肺部微環境修復之分子與細胞圖譜及其作用機制-臨床級胎盤間葉幹細胞對急性肺損傷/急性呼吸窘迫症之免疫調控與肺組織再生之治療機制(1/3)

  Huang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶B型肝炎誘發之肝癌腫瘤生成與Sorafenib抗藥性之微環境：聚焦發炎激素與癌幹細胞特性之轉譯精準醫學研究與臨床意義-探討微環境發炎細胞激素與基因後生調節於B型肝炎病毒誘導之肝癌表現多能性幹細胞基因OCT4與Sorafenib抗藥性之調控機制與其臨床意義(3/3)

  Huang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Novel Collagen Composite Containing MSC-EVs Improves Achilles Tendon Repair

  Huang, Y.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 再生醫學科技發展計畫(4/4)－全身安全性異體移植策略之細胞治療產品開發：標靶醫療未滿足慢性發炎相關疾病—糖尿病/褥瘡/嚴重燒燙傷之傷口癒合與多發性硬化症

  Huang, Y.

  5/1/20 → 4/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺北醫學大學自有貴重儀器共同使用服務計畫

  Huang, Y.

  12/1/19 → 12/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.( II )

  Huang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of high cell density in pIGF1R/EpCAM-induced Sorafenib resistance in HBV-HCC

  Huang, Y.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Systemic Safety Allograft Strategies for Cell Therapeutic Product Development: Targeting Unmet Medical Need Human Chronic Inflammatory Disease - Diabetes Mellitus /Decubitus Wound, Severe Burn, and Multiple Sclerosis( III )

  Huang, Y.

  5/1/19 → 4/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究-人類胎盤間質幹細胞於治療老化相關急性肺損傷之探討：安全性、有效性、與細胞產品之開發

  Huang, Y.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.(I)(1/3)

  Huang, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 再生醫學科技發展計畫－全身安全性異體移植策略之細胞治療產品開發:標靶醫療未滿足慢性發炎相關疾病-糖尿病/褥瘡/嚴重燒燙傷之傷口癒合與多發性硬化症(2/3)

  Huang, Y.

  5/1/18 → 4/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究

  Huang, Y.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 幹細胞基礎研究、前臨床動物試驗與臨床試驗

  Huang, Y.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Sorafenib抗藥性所誘發之肝癌惡病質與癌幹細胞特性之細胞療法：利用全身安全性之人類胎盤蛻膜間葉幹細胞標靶TNFα-IL6之免疫調控與攜帶奈米藥物對抗Sorafenib抗藥性肝癌之雙功能策略(先期補助)

  Huang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• 幹細胞基礎研究與前臨床動物試驗

  Huang, Y.

  8/1/16 → 7/31/17

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases --Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (II)

  Huang, Y.

  10/1/15 → 9/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• 幹細胞基礎研究與前臨床動物試驗

  Huang, Y.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 探討缺氧環境中透過Hif-2α支配的Igf-1r—Cxcr4訊號迴路調控小鼠生殖系幹細胞爬行作用機制

  Huang, Y.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases---Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (I)

  Huang, Y.

  10/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Testicular Germ Cell Tumor 100%
  • Embryonic Stem Cells 77%
  • Epigenomics 75%
  • Seminoma 73%
  • Germ Cells 71%

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• 小分子團水對降低血脂膽固醇之動物模式與其在粥狀動脈硬化症之臨床意義探討

  Huang, Y.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討胞外基質Laminin與類胰島素生長因子-1於精原幹細胞自我更新之訊息傳遞機制

  Huang, Y.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Niche Signaling Networks in Self-Renewal and Migration of Pluripotent Germline Stem Cells and Its Implication for Germline Differentiation in Human Pluripotent Stem Cells (III)

  Huang, Y.

  10/1/13 → 9/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related Hcc under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 子宮內膜異位症中乙式轉形生長因子在調控OCT4表現及上皮細胞/間葉細胞間轉型之角色探討

  Huang, Y.

  6/1/13 → 5/31/14

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Niche Signaling Networks in Self-Renewal and Migration of Pluripotent Germline Stem Cells and Its Implication for Germline Differentiation in Human Pluripotent Stem Cells (II)

  Huang, Y.

  10/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Kao, S., Huang, Y., Yang, W., Yang, W., Yeh, C., Li, Y. & Shen, S.

  8/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• Circuits of Igf-1r and Niche Signaling (Hypoxia/Inflammation) in Stem Cell Transformation and Its Clinical Implication of Molecular Target Therapy (Model of Germline Stem Cells)

  Huang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Stem Cells 86%
  • Hypoxia 55%
  • Inflammation 34%
  • Seminoma 29%

• Niche Signaling Networks in Self-Renewal and Migration of Pluripotent Germline Stem Cells and Its Implication for Germline Differentiation in Human Pluripotent Stem Cells (III)

  Huang, Y.

  10/1/11 → 9/30/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Immuno-Modulatory Effects of Xanthophylls on Male Reproductive System

  Wu, T. & Huang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • xanthophylls 100%
  • selenites 79%
  • astaxanthin 76%
  • male fertility 29%
  • prostaglandin synthase 28%

• Circuits of IGF-1R and Niche Signaling (Hypoxia/Inflammation) in Stem Cell Transformation and Its Clinical Implication of Molecular Target Therapy (Model of Germline Stem Cells)

  Huang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Stem Cells 86%
  • Hypoxia 55%
  • Inflammation 34%
  • Seminoma 29%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Shen, S., Yang, W., Li, Y., Yeh, C. & Kao, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• 100年度「轉譯醫學及農學人才培育先導型計畫」

  Lee, S., Huang, Y. & Yang, J.

  1/1/11 → 12/31/11

  Project: A - Government Institution › d - Ministry of Education

• Characterization of the Self-Renewal/Reprogramming Factors of Human/Mouse Germ Line Stem Cells in Serum-Free Culture System and Its Induction Effect on Human Embryonic Stem Cells to Sperm (Extension Proposal) (II)

  Huang, Y.

  12/1/10 → 9/30/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • stem cells 100%
  • germ cells 94%
  • hypoxia 45%
  • translational medical research 38%
  • testes 30%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Li, Y., Yang, W., Shen, S. & Kao, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• The Immuno-Modulatory Effects of Xanthophylls on Male Reproductive System

  Wu, T. & Huang, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • xanthophylls 100%
  • selenites 79%
  • astaxanthin 76%
  • male fertility 29%
  • prostaglandin synthase 28%