Yen-Chou Chen

Professor, Graduate Institute of Medical Sciences
Joint-Appointment Professor, International Master/Ph.D. Program in Medicine
Joint-Appointment Professor, International Ph.D. Program for Cell Therapy and Regeneration Medicine
Joint-Appointment Professor, Graduate Institute of Metabolism and Obesity Sciences
Joint-Appointment Professor, Master Program in Applied Molecular Epidemiology
Member, TMU Research Center of Thoracic Medicine

https://orcid.org/0000-0002-2031-4256

Emailyc3270@tmu.edu.tw

Source: Scopus
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Personal profile

Education

1993-1997 Ph.D., Department of Biochemistry, College of Medicine, National Taiwan University
1990-1992 M.S., Department of Zoology; National Taiwan University
1986-1990 B.S., Department of Zoology, National Taiwan University

Experience

2019.12- Professor, Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University
2018.02- Professor, International Ph.D Program for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan
2018.02-2020.04 Director, International Ph.D Program for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan
2018.04- Director, Professor, Master Program in Applied Molecular Epidemiology, Taipei Medical University, Taipei, Taiwan
2018.02- Director, Professor, International Master/Ph.D Program in Medicine, Taipei Medical University, Taipei, Taiwan
2016.11-2017.10 Professor, International Ph.D. Program for Cell Therapy and Regeneration Medicine, Taipei Medical University
2014-2016 Vice Director, Office of Research and Development, Taipei Medical University, Taipei, Taiwan
2013- Professor, Ph.D. Program for the Clinical Drug Discovery from Botanical Herbs, Taipei Medical University, Taipei, Taiwan
2009- Professor, Department of Pharmacology, Taipei Medical University, Taipei, Taiwan
2007.08- Professor, Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan
2007.02-2007.07 Professor, Graduate Institute of Pharmacognosy, Taipei Medical University
2003.08-2006.07 Associate professor, College of Pharmacy, Taipei Medical University
2003.02- Associate professor, Graduate Institute of Pharmacognosy, Taipei Medical University
2002-2007 Associate professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan
2000.08-2009.07 Director, Laboratory Animal Center, Taipei Medical University
1999-2002 Assistant professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan
1999.08-2003.01 Assistant professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan
1998-1999 Post-doctor fellow, Department of Pharmacology, Southern Illinois University, Springfield, U.S.A.
1997-1998 Post-doctor fellow, Department of Biochemistry, National Taiwan University, Taipei, Taiwan, R.O.C.

Research Interests

Inflammation mechanism
Anti-caner drug action mechanism

Awards

1997-1998 Post-doctor fellow Travel Award for Toxicology Proceeding of the 1st International Conference of Asian Society of Toxicology, Yokohama, Japan.
1995-1997 Graduate fellowship, Department of Biochemistry; National Taiwan University, Taipei, Taiwan

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2 Active
28 Finished

b-catenin/Slug 在人類卵巢癌細胞產生CDDP抗性的角色: Evodiamine抗卵巢癌細胞活性探討
Chen, Y.
3/1/21 → 2/28/22
Project: C - Project of Alliance › o - Chi Mei Medical Center
The molecular pathogenesis of pulmonary fibrosis-Warburg effect在肺纖維化之角色(3/3)
Chen, Y.
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
活化 JNK與PERK在Evodiamine抑制卵巢癌細胞CDDP抗性之角色
Chen, Y.
3/1/20 → 2/1/21
Project: C - Project of Alliance › o - Chi Mei Medical Center
The Role of Warburg Effect in Pulmonary Fibrosis(2/3)
Chen, Y.
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
Mechanism of Evodiamine and Its Derivatives on Inhibition of Cddp Resistance and Epithelial-Mesenchymal Transition (Emt) of Human Ovarian Carcinoma Cells
Chen, Y.
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology

5908 Citations
42 h-Index
100 Article

Cost-utility analysis of second-line anti-diabetic therapy in patients with type 2 diabetes mellitus inadequately controlled on metformin
Chien, C. L., Chen, Y. C., Malone, D. C., Peng, Y. L. & Ko, Y., 2020, (Accepted/In press) In: Current Medical Research and Opinion. 36, 10, p. 1619-1626 8 p.
Research output: Contribution to journal › Article › peer-review
Activation of PERK in ET-1- and thrombin-induced pulmonary fibroblast differentiation: Inhibitory effects of curcumin
Chen, Y. C., Chen, B. C., Huang, H. M., Lin, S. H. & Lin, C-H., Jan 1 2019, In: Journal of Cellular Physiology.
Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus)
Genetic and ethnic modulation of cardiovascular toxicity of vascular endothelial growth factor inhibitors
Chen, Y. C., Chung, C. C., Lin, Y. K. & Chen, Y. J., Jan 2 2018, In: Annals of Medicine. 50, 1, p. 46-56 11 p.
Research output: Contribution to journal › Article › peer-review
Hypoxia stimulates the epithelial-to-mesenchymal transition in lung cancer cells through accumulation of nuclear β-catenin
Liu, K. H., Tsai, Y. T., Chin, S. Y., Lee, W. R., Chen, Y. C. & Shen, S. C., Nov 1 2018, In: Anticancer Research. 38, 11, p. 6299-6308 10 p.
Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus)
MPT0B169 and MPT0B002, New Tubulin Inhibitors, Induce Growth Inhibition, G2/M Cell Cycle Arrest, and Apoptosis in Human Colorectal Cancer Cells
Lee, C. H., Lin, Y. F., Chen, Y. C., Wong, S. M., Juan, S. H. & Huang, H. M., Jan 1 2018, (Accepted/In press) In: Pharmacology. p. 262-271 10 p.
Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus)