Yao-An Shen

https://orcid.org/0000-0002-4393-2794

Emailshen1202@tmu.edu.tw

Source: Scopus
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Personal profile

Education

2009-2015 Ph.D., Institute of Biochemistry and Molecular Biology, National Yang Ming University
2007-2009 M.S., Department of Life Sciences and Institute of Genome Sciences, National Yang Ming University
2000-2004 B.S., Department of Life Science, Tzu Chi University

Experience

2020.02- Assistant Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
2019.06- Assistant Professor, Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University
2016.08-2019.06 Postdoctoral Research Fellow, Johns Hopkins University
2015.08-2016.08 Postdoctoral Research Fellow, National Yang-Ming University
2015.02-2015.07 Postdoctoral Research Fellow, Taipei Veterans General Hospital

Research Interests

Translational Medicine, Cancer Stem Cell, Metabolism, Nanomedicine

Awards

2018.03.14 Pathology Award – 20th Annual Department of Pathology Young Investigators' Day, Johns Hopkins University, USA
2016.11.28 Postdoctoral Research Abroad Program (PRAP) Award – Ministry of Science and Technology, Taiwan
2013.11.06 Young Investigator Award – International Symsposium on Mitochondria 2013 / The 13th Conference of Japanese Society of Mitochondrial Research and Medicine (J-mit), Japan
2013.11.04 Young Investigator Award – 10th Conference of the Asian Society of Mitochondrial Research and Medicine (ASMRM), Korea
2013.10.19 First prize of Poster Award – 2013 Mini-symposium on Mitochondria and Aging, Taiwan
2013.10.16 Young Investigator Award – 6th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), Taiwan
2013.09.07 Third Prize of Poster Award – 2013 International Symposium on Mitochondrial Dynamics in Translational Medicine, Taiwan
2012.11.02 Young Investigator Award – 2012 Conference of 9th ASMRM Beijing, China
2012.10.26 Silver Medal Award of Oral Session Competition – 7th International Symposium on Genomic Medicine of CCH, Taiwan
2011.10.07 Fellowships Award – 22nd FAOBMB Conference, Singapore
2011.08.31 Young Investigator Award – 2011 8th Conference of ASMRM in Kagoshima, Japan
2011.07.09 First prize of Poster Award – 2011 Mackay International Symposium on Mitochondrial Medicine in Human Health and Diseases in Taipei, Taiwan
2010.12.15 Young Investigator Award – 2010 7th Conference of ASMRM in Fukuoka, Japan

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3 Finished

探討溶酶體酸性磷酸酶二在轉移性大腸直腸癌幹細胞中扮演的角色
Shen, Y.
7/1/20 → 2/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
Reversing metabolic compensation to overcome recurrence in ovarian cancer by inhibition of MYC/GLS axis(1/3)
Shen, Y.
2/1/20 → 1/31/21
Project: A - Government Institution › b - Ministry of Science and Technology
新聘教師研究補助
Shen, Y.
9/1/19 → 8/31/20
Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

338 Citations
9 h-Index
12 Article
1 Review article

Targeting cancer stem cells from a metabolic perspective
Shen, Y. A., Pan, S. C., Chu, I., Lai, R. Y. & Wei, Y. H., Mar 1 2020, In: Experimental Biology and Medicine. 245, 5, p. 465-476 12 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
3 Citations (Scopus)
The feasibility of ROS- and GSH-responsive micelles for treating tumor-initiating and metastatic cancer stem cells
Yu, L-Y., Shen, Y-A., Chen, M-H., Wen, Y-H., Hsieh, P-I. & Lo, C-L., Jan 1 2019, In: Journal of Materials Chemistry B. 7, 19, p. 3109-3118 10 p.
Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus)
Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer
Nguyen, T., Kirsch, B. J., Asaka, R., Nabi, K., Quinones, A., Tan, J., Antonio, M. J., Camelo, F., Li, T., Nguyen, S., Hoang, G., Nguyen, K., Udupa, S., Sazeides, C., Shen, Y-A., Elgogary, A., Reyes, J., Zhao, L., Kleensang, A., Chaichana, K. L. & 7 others, Hartung, T., Betenbaugh, M. J., Marie, S. K., Jung, J. G., Wang, T-L., Gabrielson, E. & Le, A., Apr 9 2019, In: Cell Reports. 27, 2, p. 491-501.e6
Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus)
pH- and GSH-Sensitive Hyaluronic Acid-MP Conjugate Micelles for Intracellular Delivery of Doxorubicin to Colon Cancer Cells and Cancer Stem Cells
Debele, T. A., Yu, L-Y., Yang, C-S., Shen, Y-A. & Lo, C-L., Sep 10 2018, In: Biomacromolecules. 19, 9, p. 3725-3737 13 p.
Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus)
CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation
Shen, Y-A., Wang, C-Y., Chuang, H-Y., Hwang, J. J-J., Chi, W-H., Shu, C-H., Ho, C-Y., Li, W-Y. & Chen, Y-J., Sep 6 2016, In: Oncotarget. 7, 36, p. 58351-58366 16 p.
Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus)