Projects per year
Personal profile
Education
- 2009-2015 Ph.D., Institute of Biochemistry and Molecular Biology, National Yang Ming University
- 2007-2009 M.S., Department of Life Sciences and Institute of Genome Sciences, National Yang Ming University
- 2000-2004 B.S., Department of Life Science, Tzu Chi University
Experience
- 2020.02- Assistant Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2019.06- Assistant Professor, Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University
- 2016.08-2019.06 Postdoctoral Research Fellow, Johns Hopkins University
- 2015.08-2016.08 Postdoctoral Research Fellow, National Yang-Ming University
- 2015.02-2015.07 Postdoctoral Research Fellow, Taipei Veterans General Hospital
Research Interests
- Translational Medicine, Cancer Stem Cell, Metabolism, Nanomedicine
Awards
- 2018.03.14 Pathology Award – 20th Annual Department of Pathology Young Investigators' Day, Johns Hopkins University, USA
- 2016.11.28 Postdoctoral Research Abroad Program (PRAP) Award – Ministry of Science and Technology, Taiwan
- 2013.11.06 Young Investigator Award – International Symsposium on Mitochondria 2013 / The 13th Conference of Japanese Society of Mitochondrial Research and Medicine (J-mit), Japan
- 2013.11.04 Young Investigator Award – 10th Conference of the Asian Society of Mitochondrial Research and Medicine (ASMRM), Korea
- 2013.10.19 First prize of Poster Award – 2013 Mini-symposium on Mitochondria and Aging, Taiwan
- 2013.10.16 Young Investigator Award – 6th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), Taiwan
- 2013.09.07 Third Prize of Poster Award – 2013 International Symposium on Mitochondrial Dynamics in Translational Medicine, Taiwan
- 2012.11.02 Young Investigator Award – 2012 Conference of 9th ASMRM Beijing, China
- 2012.10.26 Silver Medal Award of Oral Session Competition – 7th International Symposium on Genomic Medicine of CCH, Taiwan
- 2011.10.07 Fellowships Award – 22nd FAOBMB Conference, Singapore
- 2011.08.31 Young Investigator Award – 2011 8th Conference of ASMRM in Kagoshima, Japan
- 2011.07.09 First prize of Poster Award – 2011 Mackay International Symposium on Mitochondrial Medicine in Human Health and Diseases in Taipei, Taiwan
- 2010.12.15 Young Investigator Award – 2010 7th Conference of ASMRM in Fukuoka, Japan
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Projects
- 3 Finished
-
探討溶酶體酸性磷酸酶二在轉移性大腸直腸癌幹細胞中扮演的角色
7/1/20 → 2/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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Reversing metabolic compensation to overcome recurrence in ovarian cancer by inhibition of MYC/GLS axis(1/3)
2/1/20 → 1/31/21
Project: A - Government Institution › b - Ministry of Science and Technology
Research output
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Targeting cancer stem cells from a metabolic perspective
Shen, Y. A., Pan, S. C., Chu, I., Lai, R. Y. & Wei, Y. H., Mar 1 2020, In: Experimental Biology and Medicine. 245, 5, p. 465-476 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access3 Citations (Scopus) -
The feasibility of ROS- and GSH-responsive micelles for treating tumor-initiating and metastatic cancer stem cells
Yu, L-Y., Shen, Y-A., Chen, M-H., Wen, Y-H., Hsieh, P-I. & Lo, C-L., Jan 1 2019, In: Journal of Materials Chemistry B. 7, 19, p. 3109-3118 10 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer
Nguyen, T., Kirsch, B. J., Asaka, R., Nabi, K., Quinones, A., Tan, J., Antonio, M. J., Camelo, F., Li, T., Nguyen, S., Hoang, G., Nguyen, K., Udupa, S., Sazeides, C., Shen, Y-A., Elgogary, A., Reyes, J., Zhao, L., Kleensang, A., Chaichana, K. L. & 7 others, , Apr 9 2019, In: Cell Reports. 27, 2, p. 491-501.e6Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
pH- and GSH-Sensitive Hyaluronic Acid-MP Conjugate Micelles for Intracellular Delivery of Doxorubicin to Colon Cancer Cells and Cancer Stem Cells
Debele, T. A., Yu, L-Y., Yang, C-S., Shen, Y-A. & Lo, C-L., Sep 10 2018, In: Biomacromolecules. 19, 9, p. 3725-3737 13 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation
Shen, Y-A., Wang, C-Y., Chuang, H-Y., Hwang, J. J-J., Chi, W-H., Shu, C-H., Ho, C-Y., Li, W-Y. & Chen, Y-J., Sep 6 2016, In: Oncotarget. 7, 36, p. 58351-58366 16 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus)