• 306 Citations
  • 8 h-Index

Research output per year

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Personal profile


  • 2009-2015 Ph.D., Institute of Biochemistry and Molecular Biology, National Yang Ming University
  • 2007-2009 M.S., Department of Life Sciences and Institute of Genome Sciences, National Yang Ming University
  • 2000-2004 B.S., Department of Life Science, Tzu Chi University


  • 2020.02- Assistant Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
  • 2019.06- Assistant Professor, Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University
  • 2016.08-2019.06 Postdoctoral Research Fellow, Johns Hopkins University
  • 2015.08-2016.08 Postdoctoral Research Fellow, National Yang-Ming University
  • 2015.02-2015.07 Postdoctoral Research Fellow, Taipei Veterans General Hospital

Research Interests

  • Translational Medicine, Cancer Stem Cell, Metabolism, Nanomedicine


  • 2018.03.14 Pathology Award – 20th Annual Department of Pathology Young Investigators' Day, Johns Hopkins University, USA
  • 2016.11.28 Postdoctoral Research Abroad Program (PRAP) Award – Ministry of Science and Technology, Taiwan
  • 2013.11.06 Young Investigator Award – International Symsposium on Mitochondria 2013 / The 13th Conference of Japanese Society of Mitochondrial Research and Medicine (J-mit), Japan
  • 2013.11.04 Young Investigator Award – 10th Conference of the Asian Society of Mitochondrial Research and Medicine (ASMRM), Korea
  • 2013.10.19 First prize of Poster Award – 2013 Mini-symposium on Mitochondria and Aging, Taiwan
  • 2013.10.16 Young Investigator Award – 6th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), Taiwan
  • 2013.09.07 Third Prize of Poster Award – 2013 International Symposium on Mitochondrial Dynamics in Translational Medicine, Taiwan
  • 2012.11.02 Young Investigator Award – 2012 Conference of 9th ASMRM Beijing, China
  • 2012.10.26 Silver Medal Award of Oral Session Competition – 7th International Symposium on Genomic Medicine of CCH, Taiwan
  • 2011.10.07 Fellowships Award – 22nd FAOBMB Conference, Singapore
  • 2011.08.31 Young Investigator Award – 2011 8th Conference of ASMRM in Kagoshima, Japan
  • 2011.07.09 First prize of Poster Award – 2011 Mackay International Symposium on Mitochondrial Medicine in Human Health and Diseases in Taipei, Taiwan
  • 2010.12.15 Young Investigator Award – 2010 7th Conference of ASMRM in Fukuoka, Japan

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Shen, Y.


Project: A - Government Institutionb - Ministry of Science and Technology

Reversing metabolic compensation to overcome recurrence in ovarian cancer by inhibition of MYC/GLS axis(1/3)

Shen, Y.


Project: A - Government Institutionb - Ministry of Science and Technology


Shen, Y.


Project: B - Project of TMUg - Research Grants for Newly Hired Faculty

Research Output

  • 306 Citations
  • 8 h-Index
  • 12 Article
  • 1 Review article

Targeting cancer stem cells from a metabolic perspective

Shen, Y. A., Pan, S. C., Chu, I., Lai, R. Y. & Wei, Y. H., Mar 1 2020, In : Experimental Biology and Medicine. 245, 5, p. 465-476 12 p.

Research output: Contribution to journalReview article

Open Access
  • The feasibility of ROS- and GSH-responsive micelles for treating tumor-initiating and metastatic cancer stem cells

    Yu, L-Y., Shen, Y-A., Chen, M-H., Wen, Y-H., Hsieh, P-I. & Lo, C-L., Jan 1 2019, In : Journal of Materials Chemistry B. 7, 19, p. 3109-3118 10 p.

    Research output: Contribution to journalArticle

  • 4 Citations (Scopus)

    Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer

    Nguyen, T., Kirsch, B. J., Asaka, R., Nabi, K., Quinones, A., Tan, J., Antonio, M. J., Camelo, F., Li, T., Nguyen, S., Hoang, G., Nguyen, K., Udupa, S., Sazeides, C., Shen, Y-A., Elgogary, A., Reyes, J., Zhao, L., Kleensang, A., Chaichana, K. L. & 7 others, Hartung, T., Betenbaugh, M. J., Marie, S. K., Jung, J. G., Wang, T-L., Gabrielson, E. & Le, A., Apr 9 2019, In : Cell Reports. 27, 2, p. 491-501.e6

    Research output: Contribution to journalArticle

  • 15 Citations (Scopus)

    pH- and GSH-Sensitive Hyaluronic Acid-MP Conjugate Micelles for Intracellular Delivery of Doxorubicin to Colon Cancer Cells and Cancer Stem Cells

    Debele, T. A., Yu, L-Y., Yang, C-S., Shen, Y-A. & Lo, C-L., Sep 10 2018, In : Biomacromolecules. 19, 9, p. 3725-3737 13 p.

    Research output: Contribution to journalArticle

  • 13 Citations (Scopus)

    CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation

    Shen, Y-A., Wang, C-Y., Chuang, H-Y., Hwang, J. J-J., Chi, W-H., Shu, C-H., Ho, C-Y., Li, W-Y. & Chen, Y-J., Sep 6 2016, In : Oncotarget. 7, 36, p. 58351-58366 16 p.

    Research output: Contribution to journalArticle

  • 16 Citations (Scopus)