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2020

Highly expressed FOXF1 inhibit non-small-cell lung cancer growth via inducing tumor suppressor and G1-phase cell-cycle arrest

Wu, C. Y., Chan, C. H., Dubey, N. K., Wei, H. J., Lu, J. H., Chang, C. C., Cheng, H. C., Ou, K. L. & Deng, W. P., May 2 2020, In : International journal of molecular sciences. 21, 9, 3227.

Research output: Contribution to journalArticle

Open Access
2019

Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade

Dubey, N. K., Wei, H-J., Yu, S. H., Williams, D. F., Wang, J. R., Deng, Y. H., Tsai, F. C., Wang, D. P. & Deng, W-P., 2019, In : Aging and Disease.

Research output: Contribution to journalArticle

Cerebro- and renoprotective activities through platelet-derived biomaterials against cerebrorenal syndrome in rat model

Yip, H. K., Chen, K. H., Dubey, N. K., Sun, C. K., Deng, Y. H., Su, C. W., Lo, W. C., Cheng, H. C. & Deng, W. P., Sep 1 2019, In : Biomaterials. 214, 119227.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Time- and Kellgren⁻Lawrence Grade-Dependent Changes in Intra-Articularly Transplanted Stromal Vascular Fraction in Osteoarthritic Patients

Tran, T. D. X., Wu, C-M., Dubey, N. K., Deng, Y-H., Su, C-W., Pham, T. T., Thi Le, P. B., Sestili, P. & Deng, W-P., Apr 3 2019, In : Cells. 8, 4

Research output: Contribution to journalArticle

2018

Addressing stem cell therapeutic approaches in pathobiology of diabetes and its complications

Peng, B. Y., Dubey, N. K., Mishra, V. K., Tsai, F. C., Dubey, R., Deng, W. P. & Wei, H. J., Jan 1 2018, In : Journal of Diabetes Research. 2018, 7806435.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Combination of recurrent oral aphthae and dry eye syndrome may constitute an independent risk factor for oral cavity cancer in elderly women

Qin, L., Kao, Y. W., Lin, Y. L., Peng, B. Y., Deng, W. P., Chen, T. M., Lin, K. C., Yuan, K. S. P., Wu, A. T. H., Shia, B. C. & Wu, S. Y., Jan 1 2018, In : Cancer Management and Research. 10, p. 3273-3281 9 p.

Research output: Contribution to journalArticle

Correlation between diabetes mellitus and knee osteoarthritis: A dry-to-wet lab approach

Dubey, N. K., Ningrum, D. N. A., Dubey, R., Deng, Y-H., Li, Y-C., Wang, D. P., Wang, J. R., Syed-Abdul, S. & Deng, W-P., Jan 1 2018, In : International Journal of Molecular Sciences. 19, 10, 3021.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Mechanistic insight into hyaluronic acid and platelet-rich plasma-mediated anti-inflammatory and anti-apoptotic activities in osteoarthritic mice

Chiou, C. S., Wu, C. M., Dubey, N. K., Lo, W. C., Tsai, F. C., Xuan Tung, T. D., Hung, W. C., Hsu, W. C., Chen, W. H. & Deng, W. P., Dec 1 2018, In : Aging. 10, 12, p. 4152-4165 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

NSC 95397 suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and the ERK1/2 pathway

Dubey, N. K., Peng, B. Y., Lin, C. M., Wang, P. D., Wang, J. R., Chan, C. H., Wei, H. J. & Deng, W. P., Jun 1 2018, In : International Journal of Molecular Sciences. 19, 6, 1625.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Recurrent aphthous stomatitis may be a precursor or risk factor for specific cancers: A case-control frequency-matched study

Qin, L., Kao, Y. W., Lin, Y. L., Peng, B. Y., Deng, W. P., Chen, T. M., Lin, K. C., Yuan, K. S. P., Wu, A. T. H., Shia, B. C. & Wu, S. Y., Jan 1 2018, (Accepted/In press) In : Cancer Medicine.

Research output: Contribution to journalArticle

Tumor-targeted immunotherapy by using primary adipose-derived stem cells and an antigen-specific protein vaccine

Lu, J. H., Peng, B. Y., Chang, C. C., Dubey, N. K., Lo, W. C., Cheng, H. C., Wang, J. R., Wei, H. J. & Deng, W. P., Nov 15 2018, In : Cancers. 10, 11, 446.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2017

Inhibition of chronic prostate inflammation by hyaluronic acid through an immortalized human prostate stromal cell line model

Liu, C. M., Chen, W. H., Chiou, C. S., Lo, W. C., Dubey, N. K., Chen, Y. C., Lai, W. F. T., Yeh, S. D., Chiang, H. S. & Deng, W. P., May 1 2017, In : PLoS One. 12, 5, e0178152.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Non-invasive in vivo molecular imaging of intra-articularly transplanted immortalized bone marrow stem cells for osteoarthritis treatment

Peng, B., Chiou, C-S., Dubey, N. K., Yu, S. H., Deng, Y. H., Tsai, F. C., Chiang, H. S., Shieh, Y-H., Chen, W. H. & Deng, W-P., Sep 27 2017, In : Oncotarget. 8, 57, p. 97153-97164

Research output: Contribution to journalArticle

6 Citations (Scopus)
2016

Adipose-Derived Stem Cells Enhance Cancer Stem Cell Property and Tumor Formation Capacity in Lewis Lung Carcinoma Cells Through an Interleukin-6 Paracrine Circuit

Lu, J. H., Wei, H. J., Peng, B. Y., Chou, H. H., Chen, W. H., Liu, H. Y. & Deng, W. P., Dec 1 2016, In : Stem Cells and Development. 25, 23, p. 1833-1842 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Association between anxiety state and mitral valve disorders: A Taiwanese population-wide observational study

Dubey, N. K., Syed-Abdul, S., Nguyen, P. A., Dubey, R., Usman, I., Li, Y. C., Chen, W. H. & Deng, W. P., Aug 1 2016, In : Computer Methods and Programs in Biomedicine. 132, p. 57-61 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cordyceps militaris treatment preserves renal function in type 2 diabetic nephropathy mice

Yu, S. H., Dubey, N. K., Li, W. S., Liu, M. C., Chiang, H. S., Leu, S. J., Shieh, Y. H., Tsai, F. C. & Deng, W. P., Nov 1 2016, In : PLoS One. 11, 11, e0166342.

Research output: Contribution to journalArticle

14 Citations (Scopus)
12 Citations (Scopus)

Osteoporosis recovery by antrodia camphorata alcohol extracts through bone regeneration in SAMP8 Mice

Liu, H. Y., Huang, C. F., Li, C. H., Tsai, C. Y., Chen, W. H., Wei, H. J., Wang, M. F., Kuo, Y. H., Cheong, M. L. & Deng, W. P., 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 2617868.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

Adipose-derived stem cells promote tumor initiation and accelerate tumor growth by interleukin-6 production

Wei, H. J., Zeng, R., Lu, J. H., Lai, W-F., Chen, W. H., Liu, H. Y., Chang, Y. T. & Deng, W. P., 2015, In : Oncotarget. 6, 10, p. 7713-7726 14 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Hypoglycemic Activity through a Novel Combination of Fruiting Body and Mycelia of Cordyceps militaris in High-Fat Diet-Induced Type 2 Diabetes Mellitus Mice

Yu, S. H., Chen, S. Y. T., Li, W. S., Dubey, N. K., Chen, W. H., Chuu, J. J., Leu, S. J. & Deng, W. P., 2015, In : Journal of Diabetes Research. 2015, 723190.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The potential use of platelet-rich plasma to reconstruct the microtia chondrocyte in human auricular cartilage regeneration

Chen, W. H., Liu, H. Y., Tsai, C. Y., Wu, C. C., Wei, H. J., Liu, A., Lai, M-T., Huang, C. F. & Deng, W. P., 2015, In : Journal of Nanomaterials. 2015, 250615.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

Contrast enhancement of iohexol-cisplatin-gelatin complex under computed tomography imaging

Liu, W. H., Wang, Y-K., Wu, C-C., Deng, W-P., Lin, K. H., Lo, W-C. & Tseng, C-L., May 1 2014, In : Journal of Polymer Engineering. 34, 3, p. 267-271 5 p.

Research output: Contribution to journalArticle

Delayed animal aging through the recovery of stem cell senescence by platelet rich plasma

Liu, H. Y., Huang, C. F., Lin, T. C., Tsai, C. Y., Tina Chen, S. Y., Liu, A., Chen, W. H., Wei, H. J., Wang, M. F., Williams, D. F. & Deng, W. P., Dec 1 2014, In : Biomaterials. 35, 37, p. 9767-9776 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Establishment of a promising human nucleus pulposus cell line for intervertebral disc tissue engineering

Liu, M. C., Chen, W. H., Wu, L. C., Hsu, W. C., Lo, W. C., Yeh, S. D., Wang, M. F., Zeng, R. & Deng, W. P., Jan 1 2014, In : Tissue Engineering - Part C: Methods. 20, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Extracellular matrix-regulated neural differentiation of human multipotent marrow progenitor cells enhances functional recovery after spinal cord injury

Deng, W. P., Yang, C. C., Yang, L. Y., Chen, C. W. D., Chen, W. H., Yang, C. B., Chen, Y. H., Lai, W-F. & Renshaw, P. F., Oct 1 2014, In : Spine Journal. 14, 10, p. 2488-2499 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells

Wei, H. J., Nickoloff, J. A., Chen, W. H., Liu, H. Y., Lo, W. C., Chang, Y. T., Yang, P. C., Wu, C. W., Williams, D. F., Gelovani, J. G. & Deng, W. P., 2014, In : Oncotarget. 5, 19, p. 9514-9529 16 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Synergistic anabolic actions of hyaluronic acid and platelet-rich plasma on cartilage regeneration in osteoarthritis therapy

Chen, W. H., Lo, W-C., Hsu, W. C., Wei, H. J., Liu, H. Y., Lee, C-H., Tina Chen, S. Y., Shieh, Y-H., Williams, D. F. & Deng, W-P., 2014, In : Biomaterials. 35, 36, p. 9599-9607 9 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Wnts enhance neurotrophin-induced neuronal differentiation in adult bone-marrow-derived mesenchymal stem cells via canonical and noncanonical signaling pathways

Tsai, H. L., Deng, W. P., Lai, W-F. T., Chiu, W. T., Yang, C. B., Tsai, Y. H., Hwang, S. M. & Renshaw, P. F., Aug 29 2014, In : PLoS One. 9, 8, e104937.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2013

Application of galactose-modified liposomes as a potent antigen presenting cell targeted carrier for intranasal immunization

Wang, H. W., Jiang, P. L., Lin, S. F., Lin, H. J., Ou, K. L., Deng, W. P., Lee, L. W., Huang, Y. Y., Liang, P. H. & Liu, D. Z., Mar 2013, In : Acta Biomaterialia. 9, 3, p. 5681-5688 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Potential osteoporosis recovery by deep sea water through bone regeneration in SAMP8 mice

Liu, H. Y., Liu, M. C., Wang, M. F., Chen, W. H., Tsai, C. Y., Wu, K. H., Lin, C. T., Shieh, Y. H., Zeng, R. & Deng, W. P., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 161976.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Preferential therapy for osteoarthritis by cord blood MSCs through regulation of chondrogenic cytokines

Lo, W. C., Chen, W. H., Lin, T. C., Hwang, S. M., Zeng, R., Hsu, W. C., Chiang, Y. M., Liu, M. C., Williams, D. F. & Deng, W. P., Jul 2013, In : Biomaterials. 34, 20, p. 4739-4748 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2012

Sonoporation-mediated anti-angiogenic gene transfer into muscle effectively regresses distant orthotopic tumors

Liao, Z. K., Tsai, K. C., Wang, H. T., Tseng, S. H., Deng, W. P., Chen, W. S. & Hwang, L. H., Mar 2012, In : Cancer Gene Therapy. 19, 3, p. 171-180 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

The effect of diminished osteogenic signals on reduced osteoporosis recovery in aged mice and the potential therapeutic use of adipose-derived stem cells

Liu, H. Y., Chiou, J. F., Wu, A. T. H., Tsai, C. Y., Leu, J. D., Ting, L. L., Wang, M. F., Chen, H. Y., Lin, C. T., Williams, D. F. & Deng, W. P., Sep 2012, In : Biomaterials. 33, 26, p. 6105-6112 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

The role of the ERK1/2 pathway as an alternative to the aging-diminished cyclic AMP pathway in calcitonin-mediated chondrogenesis in human nucleus pulposus

Chen, W. H., Zeng, R., Lo, W. C., Tina Chen, S. Y., Lai, T-I., Williams, D. F. & Deng, W. P., Nov 2012, In : Biomaterials. 33, 33, p. 8256-8264 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2011
14 Citations (Scopus)

Identification of antrocin from antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells

Rao, Y. K., Wu, A. T. H., Geethangili, M., Huang, M. T., Chao, W. J., Wu, C. H., Deng, W. P., Yeh, C-T. & Tzeng, Y. M., Feb 18 2011, In : Chemical Research in Toxicology. 24, 2, p. 238-245 8 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Lifelong reporter gene imaging in the lungs of mice following polyethyleneimine-mediated sleeping-beauty transposon delivery

Lin, E. H., Keramidas, M., Rome, C., Chiu, W. T., Wu, C. W., Coll, J. L. & Deng, W. P., Mar 2011, In : Biomaterials. 32, 7, p. 1978-1985 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Regenerative potentials of platelet-rich plasma enhanced by collagen in retrieving pro-inflammatory cytokine-inhibited chondrogenesis

Wu, C. C., Chen, W. H., Zao, B., Lai, P. L., Lin, T. C., Lo, H. Y., Shieh, Y. H., Wu, C. H. & Deng, W. P., Sep 2011, In : Biomaterials. 32, 25, p. 5847-5854 8 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis

Liu, H. Y., Wu, A. T. H., Tsai, C. Y., Chou, K. R., Zeng, R., Wang, M. F., Chang, W. C., Hwang, S. M., Su, C-H. & Deng, W. P., Oct 2011, In : Biomaterials. 32, 28, p. 6773-6780 8 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

The development of a novel cancer immunotherapeutic platform using tumor-targeting mesenchymal stem cells and a protein vaccine

Wei, H. J., Wu, A., Hsu, C. H., Lin, Y. P., Cheng, W. F., Su, C. H., Chiu, W. T., Whang-Peng, J., Douglas, F. L. & Deng, W. P., Dec 2011, In : Molecular Therapy. 19, 12, p. 2249-2257 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Use of iQPR-H2O for bone regeneration and its potential in the improvement of osteoporosis

Lee, C-M., Cheong, M., Hsiao, W., Liu, H., Tsai, C., Wang, M., Wu, C., Chang, K., Lam, G. & Deng, W., 2011, In : BMC Musculoskeletal Disorders. 12, 227.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2010

Differential distributions of CSE1L/CAS and E-cadherin in the polarized and non-polarized epithelial glands of neoplastic colorectal epithelium

Uen, W. C., Tai, C-J., Shen, S-C., Lee, W-R., Tsao, T. Y., Deng, W-P., Chiou, H-Y., Hsu, C-H., Hsieh, C. I., Liao, C. F. & Jiang, M. C., Oct 2010, In : Journal of Molecular Histology. 41, 4-5, p. 259-266 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Identification of a new peptide for fibrosarcoma tumor targeting and imaging in vivo

Wu, C. C., Lin, E. H., Lee, Y. C., Tai, C. J., Kuo, T. H., Wang, H. E., Luo, T. Y., Fu, Y. K., Chen, H. J., Sun, M. D., Wu, C. H., Wu, C. W., Leu, S. J. & Deng, W. P., 2010, In : Journal of Biomedicine and Biotechnology. 2010, 167045.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Increased cellular apoptosis susceptibility (CSE1L/CAS) protein expression promotes protrusion extension and enhances migration of MCF-7 breast cancer cells

Tai, C. J., Shen, S. C., Lee, W. R., Liao, C. F., Deng, W. P., Chiou, H. Y., Hsieh, C. I., Tung, J. N., Chen, C. S., Chiou, J. F., Li, L. T., Lin, C. Y., Hsu, C. H. & Jiang, M. C., Oct 2010, In : Experimental Cell Research. 316, 17, p. 2969-2981 13 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Phenotypic changes in proliferation, differentiation, and migration of chondrocytes: 3D in vitro models for joint wound healing

Tsai, Y-H., Chen, C. W., Lai, W-F., Tang, J. R., Deng, W. P., Yeh, S. D., Chung, A., Zuo, C. S. & Bowley, J. F., Mar 1 2010, In : Journal of Biomedical Materials Research - Part A. 92, 3, p. 1115-1122 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
29 Citations (Scopus)
2009

Intervertebral disc regeneration in an ex vivo culture system using mesenchymal stem cells and platelet-rich plasma

Chen, W. H., Liu, H. Y., Lo, W. C., Wu, S. C., Chi, C. H., Chang, H. Y., Hsiao, S. H., Wu, C. H., Chiu, W. T., Chen, B. J. & Deng, W. P., Oct 2009, In : Biomaterials. 30, 29, p. 5523-5533 11 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

In vitro stage-specific chondrogenesis of mesenchymal stem cells committed to chondrocytes

Chen, W. H., Lai, M. T., Wu, A. T. H., Wu, C. C., Gelovani, J. G., Lin, C. T., Hung, S. C., Chiu, W. T. & Deng, W. P., Feb 2009, In : Arthritis and Rheumatism. 60, 2, p. 450-459 10 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

Transplantation of embryonic fibroblasts treated with platelet-rich plasma induces osteogenesis in SAMP8 mice monitored by molecular imaging

Lo, W. C., Chiou, J. F., Gelovani, J. G., Cheong, M. L., Lee, C-M., Liu, H. Y., Wu, C. H., Wang, M. F., Lin, C. T. & Deng, W. P., May 1 2009, In : Journal of Nuclear Medicine. 50, 5, p. 765-773 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2008

A novel cell-based therapy for contusion spinal cord injury using GDNF-delivering NIH3T3 cells with dual reporter genes monitored by molecular imaging

Lo, W. C., Hsu, C. H., Wu, A. T. H., Yang, L. Y., Chen, W. H., Chiu, W. T., Lai, W-F., Wu, C. H., Gelovani, J. G. & Deng, W. P., Sep 1 2008, In : Journal of Nuclear Medicine. 49, 9, p. 1512-1519 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)