Projects per year
Personal profile
Education
- 1989~1994, Ph. D. Degree, Graduate Institute of Agricultural Chemistry, National Taiwan University
- 1985~1989, Bachelor Degree, Department of Agricultural Chemistry, National Taiwan University
Awards
- 2011 Integrated Research Proposal Budget Award, TMU
- 2007 Total Research Proposal Budget Award, TMU
- 2007 Integrated Research Proposal Budget Award, TMU
- 2007 Bronze Research Award, TMU
- 2007 Research Achievement Award, TMU
- 2004 Candidate of Outstanding Research Award, NSC
- 2004 Silver Research Award, TMU
- 2002 Gold Research Award, TMU
- 2001 Silver Research Award, TMU
- 2000 Class A Research Award, NSC
- 1990 College Student Research Creativity Award, NSC
- 1989 National Taiwan University Presidential Award
Research Interests
- Investigation of functional activities of protein/peptides
- Evaluation of antioxidant/antiaging activities
- Antimelanogenic activities
- Antihypertensive activities
- Improvement of metabolic syndrome disorders
Experience
- Director (2010.08～2013.07), Graduate Institute of Pharmacognosy, TMU
- Professor (2007.02～) , TMU
- Associate Professor (2003.02～2007.01) , TMU
- Assistant Professor (2000.08～2003.01) , TMU
- Postdoctoral Fellow (1996.07～2000.07), Institute of Plant and Microbial Biology, Academia Sinica
- Chief (2003.08～2006.11), Sponsored Programs Section, Office of Research and Development, Taipei Medical University
- Chief (2006.07～2006.11), Planning Section, Office of Research and Development, Taipei Medical University
URL
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2010 2019
桑黃天然物hispolon及其結構衍生物延緩老化與神經退化疾病的研究:從體外試驗到體內動物模式(1/3)
8/1/18 → 7/31/19
Project: b - Ministry of Science and Technology
探討山藥儲藏性蛋白質胃蛋白酶水解之區分物及模擬水解合成之胜肽抑制二肽基胜肽酶-4活性與改善葡萄糖不耐性的可行性評估
3/1/17 → 2/28/18
Project: r - Shin Kong Wu Ho-Su Memorial Hospital
Effects of Functional Peptides Derived from Yam Dioscorin on Anti-aging Activities and Related Mechanisms
8/1/15 → 7/31/16
Project: b - Ministry of Science and Technology
Research Output 1997 2018
- 4541 Citations
- 38 h-Index
- 153 Article
135-Day Interventions of Yam Dioscorin and the Dipeptide Asn-Trp (NW) to Reduce Weight Gains and Improve Impaired Glucose Tolerances in High-Fat Diet-Induced C57BL/6 Mice
Wu, G. C., Lin, S. Y., Liang, H. J. & Hou, W. C., Jan 24 2018, In : Journal of Agricultural and Food Chemistry. 66, 3, p. 645-652 8 p.Research output: Contribution to journal › Article
Dioscorea
Glucose Intolerance
dipeptides
Dipeptides
yams
Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation
Chen, L. C., Tseng, H. J., Liu, C. Y., Huang, Y. Y., Yen, C. C., Weng, J. R., Lu, Y. L., Hou, W. C., Lin, T. E., Pan, I. H., Huang, K. K., Huang, W. J. & Hsu, K. C., Jul 3 2018, In : Frontiers in Pharmacology. 9, JUL, 708.Research output: Contribution to journal › Article
Diarylheptanoids
Histone Deacetylases
Amyloid
Alzheimer Disease
Pyrogallol
Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro
Liu, Y. H., Lu, Y. L., Liu, D. Z. & Hou, W. C., Jul 13 2017, In : Drug Design, Development and Therapy. 11, p. 2139-2147 9 p.Research output: Contribution to journal › Article
Amine Oxidase (Copper-Containing)
Hydroxyurea
Diabetes Complications
Inhibitory Concentration 50
Cardiovascular Diseases
Hot-Water Extracts from Roots of Vitis thunbergii var. taiwaniana and Identified ε-Viniferin Improve Obesity in High-Fat Diet-Induced Mice
Lu, Y. L., Lin, S. Y., Fang, S. U., Hsieh, Y. Y., Chen, C. R., Wen, C. L., Chang, C. I. & Hou, W. C., Mar 29 2017, In : Journal of Agricultural and Food Chemistry. 65, 12, p. 2521-2529 9 p.Research output: Contribution to journal › Article
viniferins
Vitis
High Fat Diet
high fat diet
Nutrition
Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease
Chen, P. T., Chen, Z. T., Hou, W. C., Yu, L. C. & Chen, R. P. Y., Jul 13 2016, In : Scientific Reports. 6, 29760.Research output: Contribution to journal › Article
Neprilysin
Curcumin
Alzheimer Disease
Up-Regulation
Aptitude