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Wen-Chi Hou

Professor

 https://orcid.org/0000-0002-9565-7018
  • 4776 Citations
  • 39 h-Index
19972019
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Personal profile

Education

  • 1989-1994 Ph. D. Degree, Graduate Institute of Agricultural Chemistry, National Taiwan University
  • 1985-1989 Bachelor Degree, Department of Agricultural Chemistry, National Taiwan University

Experience

  • 2013- Professor, Ph. D. Program for the Clinical Drug Discovery from Botanical Herbs,Taipei Medical University
  • 2007- Professor, Graduate Institute of Pharmacognosy,Taipei Medical University
  • 2016-2018 Vice Dean, Office of Research and Development, Taipei Medical University
  • 2010-2013 Director, Graduate Institute of Pharmacognosy, Taipei Medical University
  • 2003-2007 Associate Professor, Graduate Institute of Pharmacognosy,Taipei Medical University
  • 2000-2003 Assistant Professor, Graduate Institute of Pharmacognosy,Taipei Medical University
  • 1996-2000 Postdoctoral Fellow, Institute of Plant and Microbial Biology, Academia Sinica
  • 2003-2006 Chief, Sponsored Programs Section, Office of Research and Development, Taipei Medical University
  • 2006-2006 Chief, Planning Section, Office of Research and Development, Taipei Medical University

Awards

  • 2011 Integrated Research Proposal Budget Award, TMU
  • 2007 Total Research Proposal Budget Award, TMU
  • 2007 Integrated Research Proposal Budget Award, TMU
  • 2007 Bronze Research Award, TMU
  • 2007 Research Achievement Award, TMU
  • 2004 Candidate of Outstanding Research Award, NSC
  • 2004 Silver Research Award, TMU
  • 2002 Gold Research Award, TMU
  • 2001 Silver Research Award, TMU
  • 2000 Class A Research Award, NSC
  • 1990 College Student Research Creativity Award, NSC
  • 1989 National Taiwan University Presidential Award

Research Interests

  • Investigation of functional activities of protein/peptides
  • Evaluation of antioxidant/antiaging activities
  • Antimelanogenic activities
  • Antihypertensive activities
  • Improvement of metabolic syndrome disorders

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  • 3 Similar Profiles
Antioxidants Medicine & Life Sciences
sweet potatoes Agriculture & Biology
Ipomoea batatas Medicine & Life Sciences
Dioscorea Medicine & Life Sciences
yams Agriculture & Biology
storage proteins Agriculture & Biology
Trypsin Inhibitors Medicine & Life Sciences
antioxidant activity Agriculture & Biology

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2010 2019

桑黃天然物hispolon及其結構衍生物延緩老化與神經退化疾病的研究:從體外試驗到體內動物模式(1/3)

Hou, W.

8/1/18 → 7/31/19

Project: A - Government Institution › b - Ministry of Science and Technology

植物胰蛋白酶抑制劑對脂蛋白結合與代謝作用之評估

Hou, W.

8/1/17 → 7/31/18

Project: A - Government Institution › b - Ministry of Science and Technology

探討山藥儲藏性蛋白質胃蛋白酶水解之區分物及模擬水解合成之胜肽抑制二肽基胜肽酶-4活性與改善葡萄糖不耐性的可行性評估

Hou, W.

3/1/17 → 2/28/18

Project: C - Project of Alliance › r - Shin Kong Wu Ho-Su Memorial Hospital

類薑黃素保護以過氧化氫處理人類皮膚角質細胞株的研究

Hou, W.

3/1/16 → 2/28/17

Project: C - Project of Alliance › r - Shin Kong Wu Ho-Su Memorial Hospital

Effects of Functional Peptides Derived from Yam Dioscorin on Anti-aging Activities and Related Mechanisms

Hou, W.

8/1/15 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

Research Output 1997 2018

  • 4776 Citations
  • 39 h-Index
  • 153 Article

135-Day Interventions of Yam Dioscorin and the Dipeptide Asn-Trp (NW) to Reduce Weight Gains and Improve Impaired Glucose Tolerances in High-Fat Diet-Induced C57BL/6 Mice

Wu, G. C., Lin, S. Y., Liang, H. J. & Hou, W. C., Jan 24 2018, In : Journal of Agricultural and Food Chemistry. 66, 3, p. 645-652 8 p.

Research output: Contribution to journal › Article

Dioscorea
Glucose Intolerance
dipeptides
Dipeptides
yams

Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation

Chen, L. C., Tseng, H. J., Liu, C. Y., Huang, Y. Y., Yen, C. C., Weng, J. R., Lu, Y. L., Hou, W. C., Lin, T. E., Pan, I. H., Huang, K. K., Huang, W. J. & Hsu, K. C., Jul 3 2018, In : Frontiers in Pharmacology. 9, JUL, 708.

Research output: Contribution to journal › Article

Diarylheptanoids
Histone Deacetylases
Amyloid
Alzheimer Disease
Pyrogallol
1 Citation (Scopus)

Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro

Liu, Y. H., Lu, Y. L., Liu, D. Z. & Hou, W. C., Jul 13 2017, In : Drug Design, Development and Therapy. 11, p. 2139-2147 9 p.

Research output: Contribution to journal › Article

Amine Oxidase (Copper-Containing)
Hydroxyurea
Diabetes Complications
Inhibitory Concentration 50
Cardiovascular Diseases
2 Citations (Scopus)

Hot-Water Extracts from Roots of Vitis thunbergii var. taiwaniana and Identified ε-Viniferin Improve Obesity in High-Fat Diet-Induced Mice

Lu, Y. L., Lin, S. Y., Fang, S. U., Hsieh, Y. Y., Chen, C. R., Wen, C. L., Chang, C. I. & Hou, W. C., Mar 29 2017, In : Journal of Agricultural and Food Chemistry. 65, 12, p. 2521-2529 9 p.

Research output: Contribution to journal › Article

viniferins
Vitis
High Fat Diet
high fat diet
Nutrition
9 Citations (Scopus)

Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease

Chen, P. T., Chen, Z. T., Hou, W. C., Yu, L. C. & Chen, R. P. Y., Jul 13 2016, In : Scientific Reports. 6, 29760.

Research output: Contribution to journal › Article

Neprilysin
Curcumin
Alzheimer Disease
Up-Regulation
Aptitude