• 1349 Citations
  • 23 h-Index
20062020

Research output per year

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Research Output

  • 1349 Citations
  • 23 h-Index
  • 53 Article
  • 2 Comment/debate
  • 1 Conference contribution
2020

Circulating proteoglycan endocan mediates EGFR-driven progression of non-small cell lung cancer

Yang, Y-C., Pan, K-F., Lee, W-J., Chang, J-H., Tan, P., Gu, C-C., Chang, W-M., Yang, S-F., Hsiao, M., Hua, K-T. & Chien, M-H., Jun 19 2020, In : Cancer Research.

Research output: Contribution to journalArticle

Dual targeting of the p38 MAPK‐HO‐1 axis and cIAP1/XIAP by demethoxycurcumin triggers caspase‐mediated apoptotic cell death in oral squamous cell carcinoma cells

Chien, M. H., Yang, W. E., Yang, Y. C., Ku, C. C., Lee, W. J., Tsai, M. Y., Lin, C. W. & Yang, S. F., Mar 2020, In : Cancers. 12, 3, 703.

Research output: Contribution to journalArticle

Open Access

Effects of MACC1 polymorphisms on hepatocellular carcinoma development and clinical characteristics

Lin, C. H., Hsieh, M. J., Lee, H. L., Yang, S. F., Su, S. C., Lee, W. J. & Chou, Y. E., Jan 1 2020, In : Journal of Cancer. 11, 6, p. 1641-1647 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2019
Open Access
1 Citation (Scopus)
Open Access
2 Citations (Scopus)
Open Access
7 Citations (Scopus)
2018
16 Citations (Scopus)
4 Citations (Scopus)

Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress

Yang, Y. C., Chien, M. H., Liu, H. Y., Chang, Y. C., Chen, C. K., Lee, W. J., Kuo, T. C., Hsiao, M., Hua, K. T. & Cheng, T. Y., May 1 2018, In : Cancer Letters. 421, p. 28-40 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

N-α-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas

Chien, M. H., Lee, W. J., Yang, Y. C., Tan, P., Pan, K. F., Liu, Y. C., Tsai, H. C., Hsu, C. H., Wen, Y. C., Hsiao, M. & Hua, K. T., Oct 1 2018, In : Cancer Letters. 433, p. 86-98 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Stimulation of Fas/FasL-mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c-Jun activation in HL-60 leukemia cells

Wang, S. W., Chen, Y. R., Chow, J. M., Chien, M. H., Yang, S. F., Wen, Y. C., Lee, W. J. & Tseng, T. H., Jan 1 2018, (Accepted/In press) In : Molecular Carcinogenesis.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017

3′UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma

Hua, K. T., Liu, Y. F., Hsu, C. L., Cheng, T. Y., Yang, C. Y., Chang, J. S., Lee, W. J., Hsiao, M., Juan, H. F., Chien, M. H. & Yang, S. F., Dec 1 2017, In : Scientific Reports. 7, 1, 4466.

Research output: Contribution to journalArticle

27 Citations (Scopus)
5 Citations (Scopus)

Corrigendum to "Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells" [383 (2016) 282-294]

Kuo, T. C., Chen, C. K., Hua, K. T., Yu, P., Lee, W. J., Chen, M. W., Jeng, Y. M., Chien, M. H., Kuo, K. T., Hsiao, M. & Kuo, M. L., 2017, (Accepted/In press) In : Cancer Letters.

Research output: Contribution to journalArticle

Erratum: Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility (The Journal of clinical investigation (2013) 123 3 (1082-1095) PII: 91882)

Kuo, T. C., Tan, C. T., Chang, Y. W., Hong, C. C., Lee, W. J., Chen, M. W., Jeng, Y. M., Chiou, J., Yu, P., Chen, P. S., Wang, M. Y., Hsiao, M., Su, J. L. & Kuo, M. L., Jan 3 2017, In : The Journal of clinical investigation. 127, 1, 1 p.

Research output: Contribution to journalComment/debate

Open Access

KSRP suppresses cell invasion and metastasis through miR-23a-mediated EGR3 mRNA degradation in non-small cell lung cancer

Chien, M. H., Lee, W. J., Yang, Y. C., Li, Y. L., Chen, B. R., Cheng, T. Y., Yang, P. W., Wang, M. Y., Jan, Y. H., Lin, Y. K., Lee, J. M., Hsiao, M., Chen, J. S. & Hua, K. T., Oct 1 2017, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1860, 10, p. 1013-1024 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
10 Citations (Scopus)
25 Citations (Scopus)
25 Citations (Scopus)

The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer

Huang, S. P., Liu, P. Y., Kuo, C. J., Chen, C. L., Lee, W. J., Tsai, Y. H. & Lin, Y. F., Jun 2 2017, In : Journal of Hematology and Oncology. 10, 1, 114.

Research output: Contribution to journalArticle

4 Citations (Scopus)
9 Citations (Scopus)

Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts

Chien, M. H., Lee, T. H., Lee, W. J., Yeh, Y. H., Li, T. K., Wang, P. C., Chen, J. J., Chow, J. M., Lin, Y. W., Hsiao, M., Wang, S. W. & Hua, K. T., Mar 1 2017, In : Cancer Letters. 388, p. 249-261 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2016
1 Citation (Scopus)

G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/β-catenin pathway

Cha, S. T., Tan, C. T., Chang, C. C., Chu, C. Y., Lee, W. J., Lin, B. Z., Lin, M. T. & Kuo, M. L., Sep 1 2016, In : Nature Cell Biology. 18, 9, p. 993-1005 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells

Kuo, T. C., Chen, C. K., Hua, K. T., Yu, P., Lee, W-J., Chen, M. W., Jeng, Y. M., Chien, M-H., Kuo, K., Hsiao, M. & Kuo, M. L., Dec 28 2016, In : Cancer Letters. 383, 2, p. 282-294 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
46 Citations (Scopus)

Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis

Lin, C. W., Yang, W. E., Lee, W. J., Hua, K. T., Hsieh, F. K., Hsiao, M., Chen, C. C., Chow, J. M., Chen, M. K., Yang, S. F. & Chien, M. H., Jul 1 2016, In : Carcinogenesis. 37, 7, p. 712-722 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity

Lin, Y. W., Lee, L. M., Lee, W. J., Chu, C. Y., Tan, P., Yang, Y. C., Chen, W. Y., Yang, S. F., Hsiao, M. & Chien, M. H., Apr 1 2016, In : Journal of Pineal Research. 60, 3, p. 277-290 14 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)
2015

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer

Wen, Y-C., Lee, W. J., Tan, P., Yang, S. F., Hsiao, M., Lee, L. M. & Chien, M. H., 2015, In : Oncotarget. 6, 25, p. 21120-21136 17 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

GIT1 promotes lung cancer cell metastasis through modulating Rac1/Cdc42 activity and is associated with poor prognosis

Chang, J. S., Su, C. Y., Yu, W. H., Lee, W. J., Liu, Y. P., Lai, T. C., Jan, Y. H., Yang, Y. F., Shen, C. N., Shew, J. Y., Lu, J., Yang, C. J., Huang, M. S., Lu, P. J., Lin, Y. F., Kuo, M. L., Hua, K. T. & Hsiao, M., 2015, In : Oncotarget. 6, 34, p. 36278-36291 14 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Interactions between environmental factors and melatonin receptor type 1A polymorphism in relation to oral cancer susceptibility and clinicopathologic development

Lin, F. Y., Lin, C. W., Yang, S. F., Lee, W. J., Lin, Y. W., Lee, L. M., Chang, J. L., Weng, W. C., Lin, C. H. & Chien, M. H., Mar 25 2015, In : PLoS One. 10, 3, e0121677.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Keap1-Nrf2 interaction suppresses cell motility in lung adenocarcinomas by targeting the S100P protein

Chien, M. H., Lee, W. J., Hsieh, F. K., Li, C. F., Cheng, T. Y., Wang, M. Y., Chen, J. S., Chow, J. M., Jan, Y. H., Hsiao, M., Hua, K. T. & Kuo, M. L., Oct 15 2015, In : Clinical Cancer Research. 21, 20, p. 4719-4732 14 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Macrophage infiltration induces gastric cancer invasiveness by activating the β-catenin pathway

Wu, M. H., Lee, W. J., Hua, K. T., Kuo, M. L. & Lin, M. T., Jul 30 2015, In : PLoS One. 10, 7, 134122.

Research output: Contribution to journalArticle

21 Citations (Scopus)
32 Citations (Scopus)

Quercetin induces mitochondrial-derived apoptosis via reactive oxygen species-mediated ERK activation in HL-60 leukemia cells and xenograft

Lee, W-J., Hsiao, M., Chang, J. L., Yang, S. F., Tseng, T. H., Cheng, C-W., Chow, J-M., Lin, K. H., Lin, Y. W., Liu, C. C., Lee, L-M. & Chien, M-H., Jul 15 2015, In : Archives of Toxicology. 89, 7, p. 1103-1117 15 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
14 Citations (Scopus)
74 Citations (Scopus)
2014

Associations of VEGF-C genetic polymorphisms with urothelial cell carcinoma susceptibility differ between smokers and non-smokers in Taiwan

Tung, M. C., Hsieh, M. J., Wang, S. S., Yang, S. F., Chen, S. S., Wang, S. W., Lee, L. M., Lee, W. J. & Chien, M. H., Mar 7 2014, In : PLoS One. 9, 3, e91147.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Leukocyte cell-derived chemotaxin 2 antagonizes MET receptor activation to suppress hepatocellular carcinoma vascular invasion by protein tyrosine phosphatase 1B recruitment

Chen, C. K., Yang, C. Y., Hua, K. T., Ho, M. C., Johansson, G., Jeng, Y. M., Chen, C. N., Chen, M. W., Lee, W. J., Su, J. L., Lai, T. C., Chou, C. C., Ho, B. C., Chang, C. F., Lee, P. H., Chang, K. J., Hsiao, M., Lin, M. T. & Kuo, M. L., Mar 2014, In : Hepatology. 59, 3, p. 974-985 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells

Hsiao, P. C., Lee, W-J., Yang, S. F., Tan, P., Chen, H. Y., Lee, L-M., Chang, J. L., Lai, G-M., Chow, J-M. & Chien, M-H., Dec 1 2014, In : Tumor Biology. 35, 12, p. 11903-11911 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Pterostilbene simultaneously induced G0/G1-phase arrest and MAPK-mediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell lines

Hsiao, P. C., Chou, Y. E., Tan, P., Lee, W-J., Yang, S. F., Chow, J-M., Chen, H. Y., Lin, C-H., Lee, L-M. & Chien, M-H., Aug 21 2014, In : PLoS One. 9, 8, e105342.

Research output: Contribution to journalArticle

35 Citations (Scopus)
8 Citations (Scopus)

Vascular endothelial growth factor-C modulates proliferation and chemoresistance in acute myeloid leukemic cells through an endothelin-1-dependent induction of cyclooxygenase-2

Hua, K. T., Lee, W. J., Yang, S. F., Chen, C. K., Hsiao, M., Ku, C. C., Wei, L. H., Kuo, M. L. & Chien, M. H., Feb 2014, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 2, p. 387-397 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

α-Solanine inhibits invasion of human prostate cancer cell by suppressing epithelial-mesenchymal transition and MMPs expression

Shen, K. H., Liao, A. C. H., Hung, J. H., Lee, W. J., Hu, K. C., Lin, P. T., Liao, R. F. & Chen, P. S., 2014, In : Molecules. 19, 8, p. 11896-11914 19 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2013

Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility

Kuo, T. C., Tan, C. T., Chang, Y. W., Hong, C. C., Lee, W. J., Chen, M. W., Jeng, Y. M., Chiou, J., Yu, P., Chen, P. S., Wang, M. Y., Hsiao, M., Su, J. L. & Kuo, M. L., Mar 1 2013, In : Journal of Clinical Investigation. 123, 3, p. 1082-1095 14 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Combined Effects of ICAM-1 Single-Nucleotide Polymorphisms and Environmental Carcinogens on Oral Cancer Susceptibility and Clinicopathologic Development

Lin, C. W., Chuang, C. Y., Tang, C. H., Chang, J. L., Lee, L-M., Lee, W-J., Chow, J-M., Yang, S. F. & Chien, M-H., Sep 12 2013, In : PLoS One. 8, 9, e72940.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2012

Estimating the Delivery Efficiency of Drug-Loaded Microbubbles in Cancer Cells with Ultrasound and Bioluminescence Imaging

Liao, A. H., Li, Y. K., Lee, W. J., Wu, M. F., Liu, H. L. & Kuo, M. L., Nov 2012, In : Ultrasound in Medicine and Biology. 38, 11, p. 1938-1948 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2011

Estimate the delivery efficiency in cancer cells of drug-loaded microbubbles with US and IVIS

Li, Y. K., Lee, W. J., Wu, M. F., Liu, H. L., Kuo, M. L., Wang, C. H. & Liao, A. H., 2011, IEEE International Ultrasonics Symposium, IUS. p. 1470-1473 4 p. 6293327

Research output: Chapter in Book/Report/Conference proceedingConference contribution

N-α-Acetyltransferase 10 Protein Suppresses Cancer Cell Metastasis by Binding PIX Proteins and Inhibiting Cdc42/Rac1 Activity

Hua, K. T., Tan, C. T., Johansson, G., Lee, J. M., Yang, P. W., Lu, H. Y., Chen, C. K., Su, J. L., Chen, P. B., Wu, Y. L., Chi, C. C., Kao, H. J., Shih, H. J., Chen, M. W., Chien, M. H., Chen, P. S., Lee, W. J., Cheng, T. Y., Rosenberger, G., Chai, C. Y. & 6 others, Yang, C. J., Huang, M. S., Lai, T. C., Chou, T. Y., Hsiao, M. & Kuo, M. L., Feb 15 2011, In : Cancer Cell. 19, 2, p. 218-231 14 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)