Projects per year
Personal profile
Education
- 2004-2008 Ph.D., Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University
- 2001-2004 M.S., Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University
Experience
- Deputy Director, Department of Medical Research, Taipei Municipal Wanfang Hospital
- 2015.11- Assistant Professor, Department of Urology, School of Medicine, Taipei Medical University
- 2013.04- Assistant Researcher, Taipei Municipal Wanfang Hospital
- 2012.08-2013.03 Research Assistant, Division of Cardiology, Tao-Yuan General Hospital, Ministry of Health and Welfare
- 2008.08-2011.07 Postdoctoral Researcher, Graduate Institute of Toxicology, College of Medicine, National Taiwan University
Research Interests
- 醫學之生化及分子生物
- 藥理及毒理
Awards
- 2015 萬芳醫學中心論文獎(第二名)
Fingerprint
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Recent external collaboration on country level. Dive into details by clicking on the dots or
Projects
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闡明SPOCK1/PI3K/AKT訊息路徑在透明細胞腎細胞癌對舒尼替尼抗藥性的潛在機制
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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應用人源性腫瘤組織異種移植模型發展熱療作為膀胱原位癌患者的輔助治療策略
1/1/20 → 12/1/20
Project: B - Project of TMU › h - Higher Education Sprout Project
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Unraveling the Underlying Mechanism of Spock1 in Melatonin Suppression of Breast Cancer Cell Transendothelial Migration and Metastasis
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
Research output
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Circulating proteoglycan endocan mediates EGFR-driven progression of non-small cell lung cancer
Yang, Y-C., Pan, K-F., Lee, W-J., Chang, J-H., Tan, P., Gu, C-C., Chang, W-M., Yang, S-F., Hsiao, M., Hua, K-T. & Chien, M-H., Jun 19 2020, (E-pub ahead of print) In: Cancer Research.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
DNA polymerase theta repression enhances the docetaxel responsiveness in metastatic castration-resistant prostate cancer
Kuei, C. H., Lin, H. Y., Lin, M. H., Lee, H. H., Lin, C. H., Lee, W. J., Chen, Y. L., Lu, L. S., Zheng, J. Q., Hung, R. C., Chiu, H. W., Chen, K. C. & Lin, Y. F., Dec 1 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 12, p. 165954 165954.Research output: Contribution to journal › Article › peer-review
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Dual targeting of the p38 MAPK‐HO‐1 axis and cIAP1/XIAP by demethoxycurcumin triggers caspase‐mediated apoptotic cell death in oral squamous cell carcinoma cells
Chien, M. H., Yang, W. E., Yang, Y. C., Ku, C. C., Lee, W. J., Tsai, M. Y., Lin, C. W. & Yang, S. F., Mar 2020, In: Cancers. 12, 3, 703.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Effects of MACC1 polymorphisms on hepatocellular carcinoma development and clinical characteristics
Lin, C. H., Hsieh, M. J., Lee, H. L., Yang, S. F., Su, S. C., Lee, W. J. & Chou, Y. E., Jan 1 2020, In: Journal of Cancer. 11, 6, p. 1641-1647 7 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Melatonin-triggered post-transcriptional and post-translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma
Wen, Y. C., Lin, Y. W., Chu, C. Y., Yang, Y. C., Yang, S. F., Liu, Y. F., Hsiao, M., Lee, W. J. & Chien, M. H., Sep 1 2020, In: Journal of Pineal Research. 69, 2, e12668.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)
Datasets
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v1, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/1
Dataset
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Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses
Wu, S. (Contributor), Wen, Y. (Contributor), Ku, C. (Contributor), Yang, Y. (Contributor), Chow, J. (Contributor), Yang, S. (Contributor), Lee, W. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Aug 31 2019
DOI: 10.6084/m9.figshare.c.4650602.v1, https://springernature.figshare.com/collections/Penfluridol_triggers_cytoprotective_autophagy_and_cellular_apoptosis_through_ROS_induction_and_activation_of_the_PP2A-modulated_MAPK_pathway_in_acute_myeloid_leukemia_with_different_FLT3_statuses/4650602/1
Dataset
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The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer
Huang, S. (Contributor), Liu, P. (Contributor), Kuo, C. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Tsai, Y. (Contributor) & Lin, Y. (Contributor), Unknown Publisher, Jun 2 2017
DOI: 10.6084/m9.figshare.c.3794620.v1, https://figshare.com/collections/The_G_h-PLC_1_signaling_axis_drives_metastatic_progression_in_triple-negative_breast_cancer/3794620/1
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v3, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/3
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v2, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/2
Dataset