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Personal profile

Education

  • 1996-2002 Ph. D., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
  • 1992-1995 M. S., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
  • 1988-1992 B. S., School of Pharmacy, Taipei Medical University

Experience

  • 2016-2019 Director, Department of Pharmaceutical Sciences, Taipei Medical University
  • 2017.08- Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
  • 2011.08-2017.07 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
  • 2007.08-2011.07 Assistant Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
  • 2004.08-2007.07 Assistant Professor, Department of Nursing, Chang Gung University of Science and Technology, Chiayi campus, Taiwan.
  • 2003.09-2004.07 Postdoctoral Fellow, Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan.
  • 2002.08-2003.08 Postdoctoral Fellow, Drug Research Center, National Taiwan University, Taipei, Taiwan

Research Interests

  • Total synthesis and chemical modification of naturalproduct
  • Development of natural product scaffold
  • Structure-based drug design
  • Microwave-assisted organic synthesis

Fingerprint Dive into the research topics where Wei-Jan Huang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Histone Deacetylase Inhibitors Medicine & Life Sciences
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Clerodendrum Medicine & Life Sciences
Glutamic Acid Medicine & Life Sciences
Propolis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2010 2020

開發多標靶抗阿茲海默症藥物

Huang, W.

8/1/197/1/20

Project: A - Government Institutionb - Ministry of Science and Technology

黃偉展-107研究計畫績效獎

Huang, W.

8/1/187/31/20

Project: B - Project of TMUh - Other (Funded by TMU)

以acridine為scaffold透過雙標靶策略發展新穎抗癌藥物(3/3)

Huang, W.

8/1/187/1/19

Project: A - Government Institutionb - Ministry of Science and Technology

以acridine為scaffold透過雙標靶策略發展新穎抗癌藥物(2/3)

Huang, W.

8/1/177/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

以小分子化合物開發新穎且具選擇性塗藥用於血管支架(先期補助)

Huang, W.

8/1/177/31/18

Project: A - Government Institutionf - Other (Funded by Government)

Research Output 2002 2019

  • 1304 Citations
  • 21 h-Index
  • 81 Article

HDAC8 inhibitor WK2-16 therapeutically targets lipopolysaccharide-induced mouse model of neuroinflammation and microglial activation

Lin, F. L., Yen, J. L., Kuo, Y. C., Kang, J. J., Cheng, Y. W., Huang, W. J. & Hsiao, G., Jan 2 2019, In : International Journal of Molecular Sciences. 20, 2, p. 410 410.

Research output: Contribution to journalArticle

Neuroglia
inhibitors
mice
Lipopolysaccharides
Chemical activation

Low-luminance blue light-enhanced phototoxicity in A2E-Laden RPE cell cultures and rats

Lin, C. H., Wu, M. R., Huang, W. J., Chow, D. S. L., Hsiao, G. & Cheng, Y. W., Apr 1 2019, In : International Journal of Molecular Sciences. 20, 7, 1799.

Research output: Contribution to journalArticle

Open Access
Phototoxic Dermatitis
Retinal Pigments
luminance
pigments
Cell culture

A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., Mar 1 2018, In : Frontiers in Pharmacology. 9, MAR, p. 1-17 17 p., 167.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Cell Death
Microtubules
Liver
Phosphorylation
5 Citations (Scopus)

Cerebellar α6-subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders

Chiou, L-C., Lee, H-J., Ernst, M., Huang, W-J., Chou, J-F., Chen, H-L., Mouri, A., Chen, L-C., Treven, M., Mamiya, T., Fan, P-C., Knutson, D. E., Witzigmann, C., Cook, J., Sieghart, W. & Nabeshima, T., 2018, In : British Journal of Pharmacology. 175, 12, p. 2414-2427 14 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Methamphetamine
Sensory Gating
Furosemide
Startle Reflex

Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation

Chen, L. C., Tseng, H. J., Liu, C. Y., Huang, Y. Y., Yen, C. C., Weng, J. R., Lu, Y. L., Hou, W. C., Lin, T. E., Pan, I. H., Huang, K. K., Huang, W. J. & Hsu, K. C., Jul 3 2018, In : Frontiers in Pharmacology. 9, JUL, 708.

Research output: Contribution to journalArticle

Diarylheptanoids
Histone Deacetylases
Amyloid
Alzheimer Disease
Pyrogallol