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Personal profile

Education

  • 1996-2002 Ph. D., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
  • 1992-1995 M. S., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
  • 1988-1992 B. S., School of Pharmacy, Taipei Medical University

Experience

  • 2016-2019 Director, Department of Pharmaceutical Sciences, Taipei Medical University
  • 2017.08- Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
  • 2011.08-2017.07 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
  • 2007.08-2011.07 Assistant Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
  • 2004.08-2007.07 Assistant Professor, Department of Nursing, Chang Gung University of Science and Technology, Chiayi campus, Taiwan.
  • 2003.09-2004.07 Postdoctoral Fellow, Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan.
  • 2002.08-2003.08 Postdoctoral Fellow, Drug Research Center, National Taiwan University, Taipei, Taiwan

Research Interests

  • Total synthesis and chemical modification of naturalproduct
  • Development of natural product scaffold
  • Structure-based drug design
  • Microwave-assisted organic synthesis

Fingerprint Dive into the research topics where Wei-Jan Huang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Histone Deacetylase Inhibitors Medicine & Life Sciences
Histone Deacetylases Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Cells Chemical Compounds
Derivatives Chemical Compounds
Clerodendrum Medicine & Life Sciences
Glutamic Acid Medicine & Life Sciences
Triple Negative Breast Neoplasms Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2010 2020

開發多標靶抗阿茲海默症藥物

Huang, W.

8/1/197/1/20

Project: A - Government Institutionb - Ministry of Science and Technology

黃偉展-107研究計畫績效獎

Huang, W.

8/1/187/31/20

Project: B - Project of TMUh - Other (Funded by TMU)

以acridine為scaffold透過雙標靶策略發展新穎抗癌藥物(3/3)

Huang, W.

8/1/187/1/19

Project: A - Government Institutionb - Ministry of Science and Technology

以小分子化合物開發新穎且具選擇性塗藥用於血管支架(先期補助)

Huang, W.

8/1/177/31/18

Project: A - Government Institutionf - Other (Funded by Government)

以acridine為scaffold透過雙標靶策略發展新穎抗癌藥物(2/3)

Huang, W.

8/1/177/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 2002 2019

  • 1380 Citations
  • 22 h-Index
  • 83 Article

A new histone deacetylase inhibitor enhances radiation sensitivity through the induction of misfolded protein aggregation and autophagy in triple-negative breast cancer

Chiu, H. W., Yeh, Y. L., Ho, S. Y., Wu, Y. H., Wang, B. J., Huang, W. J., Ho, Y. S., Wang, Y. J., Chen, L. C. & Tu, S. H., Nov 1 2019, In : Cancers. 11, 11, 1703.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Radiation Tolerance
Autophagy
Proteins
1 Citation (Scopus)

HDAC8 inhibitor WK2-16 therapeutically targets lipopolysaccharide-induced mouse model of neuroinflammation and microglial activation

Lin, F. L., Yen, J. L., Kuo, Y. C., Kang, J. J., Cheng, Y. W., Huang, W. J. & Hsiao, G., Jan 2 2019, In : International Journal of Molecular Sciences. 20, 2, p. 410 410.

Research output: Contribution to journalArticle

Neuroglia
inhibitors
mice
Lipopolysaccharides
Chemical activation

Induction of Apoptosis and Autophagy in Breast Cancer Cells by a Novel HDAC8 Inhibitor

Chiu, C. F., Chin, H. K., Huang, W. J., Bai, L. Y., Huang, H. Y. & Weng, J. R., Dec 4 2019, In : Biomolecules. 9, 12

Research output: Contribution to journalArticle

Open Access
Autophagy
Peroxisome Proliferator-Activated Receptors
MCF-7 Cells
Cells
Apoptosis
1 Citation (Scopus)

Low-luminance blue light-enhanced phototoxicity in A2E-Laden RPE cell cultures and rats

Lin, C. H., Wu, M. R., Huang, W. J., Chow, D. S. L., Hsiao, G. & Cheng, Y. W., Apr 11 2019, In : International Journal of Molecular Sciences. 20, 7, 1799.

Research output: Contribution to journalArticle

Open Access
Phototoxic Dermatitis
Retinal Pigments
luminance
pigments
Cell culture
2 Citations (Scopus)

A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., Mar 1 2018, In : Frontiers in Pharmacology. 9, MAR, p. 1-17 17 p., 167.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Cell Death
Microtubules
Liver
Phosphorylation