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Wei-Chun HuangFu

Assistant Professor

 https://orcid.org/0000-0002-6150-9121
  • 384 Citations
  • 11 h-Index
20032019
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Personal profile

Education

  • Ph.D. in Molecular and Cellular Toxicology, North Carolina State University
  • MEM, Nicholas School of the Environment and Earth Sciences, Duke University
  • BS in Atomic Science, National Tsing-Hua Unversity

Research Interests

  • Cancer Biology
  • Signal Transduction
  • Molecular Toxicology

Experience

  • University of Pennsylvania, Postdoctoral fellow
  • PharmaEssentia Corp. Senior Scientist

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2019

開發新穎性DYRK1A抑制劑應用於阿茲海默症之治療

HuangFu, W.

8/1/18 → 7/31/19

Project: b - Ministry of Science and Technology

Pharmacological Role of a Novel Dual-Targeting Hdacs/Microtubule Inhibitor 21-277 Inhibits Human Cancer Cells Growth in Vitro and in Vivo

HuangFu, W.

8/1/16 → 7/31/17

Project: b - Ministry of Science and Technology

高功率奈米製程之摻鉺光纖雷射在皮膚分段光熱分解療法之應用

HuangFu, W.

1/1/16 → 12/31/16

Project: i - National Taipei University of Technology

TMU102-AE1-B29

HuangFu, W.

1/1/14 → 12/30/16

Project: g - Research Grants for Newly Hired Faculty

Research Output 2003 2018

  • 384 Citations
  • 11 h-Index
  • 26 Article
  • 1 Letter
  • 1 Review article
2 Citations

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., Apr 25 2018, In : European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.

Research output: Contribution to journal › Article

Hydroxamic Acids
Histone Deacetylase Inhibitors
Antineoplastic Agents
Protein Isoforms
Cells

Age, but not short-term intensive swimming, affects chondrocyte turnover in zebrafish vertebral cartilage

Jian, Q. L., HuangFu, W. C., Lee, Y. H. & Liu, I. H., Jan 1 2018, In : PeerJ. 2018, 10, e5739.

Research output: Contribution to journal › Article

chondrocytes
Cartilage
Zebrafish
Chondrocytes
Danio rerio

A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo

Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 205.

Research output: Contribution to journal › Article

Tubulin Modulators
Histone Deacetylases
Neoplasms
Tubulin
Molecular Docking Simulation

Anti-TNF-α restricts dengue virus-induced neuropathy

Jhan, M. K., Huangfu, W. C., Chen, Y. F., Kao, J. C., Tsai, T. T., Ho, M. R., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Jan 1 2018, (Accepted/In press) In : Journal of Leukocyte Biology.

Research output: Contribution to journal › Article

Dengue Virus
Tumor Necrosis Factor-alpha
Encephalitis
Virus Diseases
Dengue

The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR

Kao, J. C., HuangFu, W. C., Tsai, T. T., Ho, M. R., Jhan, M. K., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Aug 1 2018, In : PLoS Neglected Tropical Diseases. 12, 8, e0006715.

Research output: Contribution to journal › Article

Niclosamide
Antiparasitic Agents
Dengue Virus
Virus Diseases
Sirolimus