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Research Output 1996 2019

  • 450 Citations
  • 13 h-Index
  • 38 Article
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Article
2019
olanzapine
Psychopathology
Schizophrenia
Quality of Life
Pharmacology

The association between the sedative loads and clinical severity indicators in the first-onset major depressive disorder

Wang, Y. C., Lin, H. T., Lu, M. L., Huang, M. C., Chen, C. H., Wu, T. H., Wang, S., Mao, W. C., Kuo, P. H. & Chen, H. C., Jan 1 2019, In : Frontiers in Psychiatry. 10, MAR, 129.

Research output: Contribution to journalArticle

Open Access
Major Depressive Disorder
Hypnotics and Sedatives
Antidepressive Agents
Lorazepam
Anxiety Disorders
2018
7 Citations (Scopus)
olanzapine
Schizophrenia
Drug Monitoring
C-Peptide
Waist Circumference
1 Citation (Scopus)

Improvement of hyperglycemia in a murine model of insulin resistance and high glucose- and inflammasome-mediated IL-1β expressions in macrophages by silymarin

Lu, C. P., Huang, C. Y., Wang, S. H., Chiu, C. H., Li, L. H., Hua, K. F. & Wu, T. H., Jun 25 2018, In : Chemico-Biological Interactions. 290, p. 12-18 7 p.

Research output: Contribution to journalArticle

Inflammasomes
Silymarin
Macrophages
Interleukin-1
Hyperglycemia
2017
19 Citations (Scopus)
Antrodia
Taiwanofungus camphoratus
Ubiquinone
Neoplastic Stem Cells
ubiquinones
2 Citations (Scopus)

Deferasirox-Iron Complex Formation Ratio as an Indicator of Long-term Chelation Efficacy in β-Thalassemia Major

Lu, M. Y., Lin, T. H., Chiang, P. H., Kuo, P. H., Wang, N., Wu, W. H., Lin, K. H. & Wu, T. H., Jan 30 2017, (Accepted/In press) In : Therapeutic Drug Monitoring.

Research output: Contribution to journalArticle

beta-Thalassemia
Iron
Ferritins
alanylglycine
Serum
2016
6 Citations (Scopus)

Anticataractogenesis Mechanisms of Curcumin and a Comparison of Its Degradation Products: An in Vitro Study

Liao, J. H., Huang, Y. S., Lin, Y. C., Huang, F. Y., Wu, S. H. & Wu, T. H., Mar 16 2016, In : Journal of Agricultural and Food Chemistry. 64, 10, p. 2080-2086 7 p.

Research output: Contribution to journalArticle

Curcumin
curcumin
in vitro studies
Degradation
ferulic acid
9 Citations (Scopus)

Application of plasma levels of olanzapine and N-desmethyl-olanzapine to monitor clinical efficacy in patients with schizophrenia

Lu, M. L., Wu, Y. X., Chen, C. H., Kuo, P. T., Chen, Y. H., Lin, C. H. & Wu, T. H., Feb 1 2016, In : PLoS One. 11, 2, e0148539.

Research output: Contribution to journalArticle

olanzapine
Schizophrenia
Plasmas
monitoring
dosage
2015
2 Citations (Scopus)

Silymarin and protein kinase A inhibitor modulate glucose-mediated mouse sperm motility: An in vitro study

Chen, Y. C., Pan, L. C., Lai, C. W., Chien, Y. S. & Wu, T. H., Sep 1 2015, In : Reproductive biology. 15, 3, p. 172-177 6 p.

Research output: Contribution to journalArticle

Silymarin
silymarin
cAMP-dependent protein kinase
Sperm Motility
Protein Kinase Inhibitors
8 Citations (Scopus)

Simultaneous Determination of Plasma Deferasirox and Deferasirox-Iron Complex Using an HPLC-UV System and Pharmacokinetics of Deferasirox in Patients with β-Thalassemia Major: Once-daily Versus Twice-daily Administration

Lu, M. Y., Wang, N., Wu, W. H., Lai, C. W., Kuo, P. H., Chiang, P. H., Lin, K. H. & Wu, T. H., Aug 1 2015, In : Clinical Therapeutics. 37, 8, p. 1751-1760 10 p.

Research output: Contribution to journalArticle

beta-Thalassemia
Iron
Pharmacokinetics
High Pressure Liquid Chromatography
deferasirox
2 Citations (Scopus)

The Comparative Studies of Binding Activity of Curcumin and Didemethylated Curcumin with Selenite: Hydrogen Bonding vs Acid-Base Interactions

Liao, J. H., Wu, T. H., Chen, M. Y., Chen, W. T., Lu, S. Y., Wang, Y. H., Wang, S. P., Hsu, Y. M., Huang, Y. S., Huang, Z. Y., Lin, Y. C., Chang, C. M., Huang, F. Y. & Wu, S. H., Dec 4 2015, In : Scientific Reports. 5, 17614.

Research output: Contribution to journalArticle

Selenious Acid
Curcumin
Hydrogen Bonding
Acids
Crystallins
2014
9 Citations (Scopus)

Carnosine ameliorates lens protein turbidity formations by inhibiting calpain proteolysis and ultraviolet C-induced degradation

Liao, J. H., Lin, I. L., Huang, K. F., Kuo, P. T., Wu, S. H. & Wu, T. H., Jun 25 2014, In : Journal of Agricultural and Food Chemistry. 62, 25, p. 5932-5938 7 p.

Research output: Contribution to journalArticle

Carnosine
Proteolysis
carnosine
Crystallins
calpain
2013
45 Citations (Scopus)

Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome

Yang, S. M., Ka, S. M., Hua, K. F., Wu, T. H., Chuang, Y. P., Lin, Y. W., Yang, F. L., Wu, S. H., Yang, S. S., Lin, S. H., Chang, J. M. & Chen, A., 2013, In : Free Radical Biology and Medicine. 61, p. 285-297 13 p.

Research output: Contribution to journalArticle

Inflammasomes
T-cells
Immunoglobulin A
T-Lymphocytes
Kidney
12 Citations (Scopus)
olanzapine
reversed-phase high performance liquid chromatography
High Pressure Liquid Chromatography
Plasmas
homocysteine
12 Citations (Scopus)

Ethosomes in hair dye products as carriers of the major compounds of black tea extracts

Yeh, M. I., Huang, H. C., Liaw, J. H., Huang, M. C., Wu, T. H., Huang, K. F. & Hsu, F-L., Jul 2013, In : International Journal of Dermatology. 52, 7, p. 868-875 8 p.

Research output: Contribution to journalArticle

Hair Dyes
Tea
Hair
Surface-Active Agents
Adsorption
2012
2 Citations (Scopus)

Combined therapy with thioridazine decreases plasma levels of quetiapine in taiwanese schizophrenic patients

Chang, S. C., Lu, M. L., Wang, Y. C., Lin, F. W., Huang, S. H., Kuo, P. H., Ho, H. O. & Wu, T. H., Jun 2012, In : Therapeutic Drug Monitoring. 34, 3, p. 345-348 4 p.

Research output: Contribution to journalArticle

Thioridazine
Therapeutics
Schizophrenia
Quetiapine Fumarate
Pharmacokinetics
16 Citations (Scopus)
Caesalpinia
Scavenging
scavenging
antioxidants
Antioxidants
20 Citations (Scopus)

High glucose increases nitric oxide generation in lipopolysaccharide- activated macrophages by enhancing activity of protein kinase C-α/δ and NF-κB

Hua, K. F., Wang, S. H., Dong, W. C., Lin, C. Y., Ho, C. L. & Wu, T. H., Oct 2012, In : Inflammation Research. 61, 10, p. 1107-1116 10 p.

Research output: Contribution to journalArticle

NF-kappa B
Protein Kinase C
Lipopolysaccharides
Nitric Oxide
Macrophages
1 Citation (Scopus)

Medical device on pharmacists' work-related musculoskeletal complaints and burnouts

Chou, Y. C., Chen, C. L. & Wu, T. H., Nov 2012, In : Ergonomics. 55, 11, p. 1420-1428 9 p.

Research output: Contribution to journalArticle

burnout
pharmacist
Pharmacists
complaint
Needles
2011
2 Citations (Scopus)

Anti-UVC irradiation and metal chelation properties of 6-benzoyl-5,7-dihydroxy-4-phenyl-chromen-2-one: An implications for anti-cataract agent

Liao, J. H., Wu, T. H., Hsu, F-L., Huang, Y. S., Chiang, P. H., Huang, Z. Y., Huang, C. H., Wu, S. H. & Lin, M. H., Oct 2011, In : International Journal of Molecular Sciences. 12, 10, p. 7059-7076 18 p.

Research output: Contribution to journalArticle

cataracts
Crystallins
chelation
Chelation
Cataract
18 Citations (Scopus)

Ditopic complexation of selenite anions or calcium cations by pirenoxine: An implication for anti-cataractogenesis

Liao, J. H., Chen, C. S., Hu, C. C., Chen, W. T., Wang, S. P., Lin, I. L., Huang, Y. H., Tsai, M. H., Wu, T. H., Huang, F. Y. & Wu, S. H., Jan 3 2011, In : Inorganic Chemistry. 50, 1, p. 365-377 13 p.

Research output: Contribution to journalArticle

Selenious Acid
Complexation
Anions
Cations
calcium
44 Citations (Scopus)
Cornus officinalis
Cornus
Phosphoenolpyruvate
insulin-dependent diabetes mellitus
Medical problems
13 Citations (Scopus)

Role of pirenoxine in the effects of catalin on in vitro ultravioletinduced lens protein turbidity and selenite-induced cataractogenesis in vivo

Hu, C. C., Liao, J. H., Hsu, K. Y., Lin, I. L., Tsai, M. H., Wu, W. H., Wei, T. T., Huang, Y. S., Chiu, S. J., Chen, H. Y., Wu, S. H. & Wu, T. H., 2011, In : Molecular Vision. 17, p. 1862-1870 9 p.

Research output: Contribution to journalArticle

Selenious Acid
Crystallins
Cataract
Lenses
Calpain
2010

Binding and cleavage of E. coli HUß by the E. coli Lon protease (Biophysical Journal (2010) 98, (129-137))

Liao, J. H., Lin, Y. C., Hsu, J., Lee, A. Y. L., Chen, T. A., Hsu, C. H., Chir, J. L., Hua, K. F., Wu, T. H., Hong, L. J., Yen, P. W., Chiou, A. & Wu, S. H., Mar 3 2010, In : Biophysical Journal. 98, 5, p. 932 1 p.

Research output: Contribution to journalArticle

Taiwan
Escherichia coli
Publications
E coli Lon protein
7 Citations (Scopus)

Binding and cleavage of E. coli HUβ by the E. coli Lon protease

Liao, J. H., Lin, Y. C., Hsu, J., Lee, A. Y. L., Chen, T. A., Hsu, C. H., Chir, J. L., Hua, K. F., Wu, T. H., Hong, L. J., Yen, P. W., Chiou, A. & Wu, S. H., Jan 6 2010, In : Biophysical Journal. 98, 1, p. 129-137 9 p.

Research output: Contribution to journalArticle

Protease La
Escherichia coli
Proteins
Adenosine Triphosphate
Rupture
13 Citations (Scopus)

Grape seed proanthocyanidin extract chelates iron and attenuates the toxic effects of 6-hydroxydopamine: Implications for Parkinson's disease

Wu, T. H., Liao, J. H., Hsu, F-L., Wu, H. R., Shen, C. K., Yuann, J. M. P. & Chen, S. T., Apr 2010, In : Journal of Food Biochemistry. 34, 2, p. 244-262 19 p.

Research output: Contribution to journalArticle

Grape Seed Extract
Iron Chelating Agents
grape seeds
Parkinson disease
Poisons
2009
13 Citations (Scopus)

Astaxanthin interacts with selenite and attenuates selenite-induced cataractogenesis

Liao, J. H., Chen, C. S., Maher, T. J., Liu, C. Y., Lin, M. H., Wu, T. H. & Wu, S. H., Mar 16 2009, In : Chemical Research in Toxicology. 22, 3, p. 518-525 8 p.

Research output: Contribution to journalArticle

Selenious Acid
Rats
Selenic Acid
astaxanthine
Calorimetry
2008
41 Citations (Scopus)

Metformin for metabolic dysregulation in schizophrenic patients treated with olanzapine

Chen, C. H., Chiu, C. C., Huang, M. C., Wu, T. H., Liu, H. C. & Lu, M. L., May 15 2008, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 32, 4, p. 925-931 7 p.

Research output: Contribution to journalArticle

olanzapine
Metformin
Antipsychotic Agents
Therapeutics
Insulin
22 Citations (Scopus)

Pharmacokinetics of olanzapine in Chinese male schizophrenic patients with various smoking behaviors

Wu, T. H., Chiu, C. C., Shen, W. W., Lin, F. W., Wang, L. H., Chen, H. Y. & Lu, M. L., Dec 12 2008, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 32, 8, p. 1889-1893 5 p.

Research output: Contribution to journalArticle

olanzapine
Pharmacokinetics
Smoking
Tobacco Products
Light
2007
17 Citations (Scopus)

Properties of astaxanthin/Ca2+ complex formation in the deceleration of Cis/trans isomerization

Chen, C. S., Wu, S. H., Wu, Y. Y., Fang, J. M. & Wu, T. H., Aug 2 2007, In : Organic Letters. 9, 16, p. 2985-2988 4 p.

Research output: Contribution to journalArticle

chelation
Deceleration
turbidity
deceleration
Isomerization
2006
5 Citations (Scopus)

A screening platform for compounds with potential immuno-regulatory activities using human cord blood mononuclear cells

Chen, C. J., Chia, C. T., Hsieh, J. F., Chien, C. M., Wu, T. H. & Chen, S. T., Dec 2006, In : Combinatorial Chemistry and High Throughput Screening. 9, 10, p. 777-784 8 p.

Research output: Contribution to journalArticle

Fetal Blood
Human Activities
Blood Cells
Screening
Blood
32 Citations (Scopus)

Astaxanthin protects against oxidative stress and calcium-induced porcine lens protein degradation

Wu, T. H., Liao, J. H., Hou, W. C., Huang, F. Y., Maher, T. J. & Hu, C. C., Mar 22 2006, In : Journal of Agricultural and Food Chemistry. 54, 6, p. 2418-2423 6 p.

Research output: Contribution to journalArticle

Crystallins
Oxidative stress
astaxanthin
protein degradation
Lens
11 Citations (Scopus)

The impact of an intensive antimicrobial control program in a Taiwanese medical center

Chang, M. T., Wu, T. H., Wang, C. Y., Jang, T. N. & Huang, C. Y., Aug 2006, In : Pharmacy World and Science. 28, 4, p. 257-264 8 p.

Research output: Contribution to journalArticle

Ciprofloxacin
Taiwan
Prescriptions
Inpatients
Serratia
2002
1 Citation (Scopus)

Antioxidative and free radical scavenging activities of phenolics from Scutellaria baicalensis

Lin, T. C., Nishikawa, K., Wu, T. H. & Ishimaru, K., Jun 2002, In : Chinese Pharmaceutical Journal. 54, 3, p. 193-198 6 p.

Research output: Contribution to journalArticle

Scutellaria baicalensis
Lamiaceae
Glycosides
Scavenging
Free radicals
2001

Growth rate and polyphenol production in transformed root cultures of Fragaria x ananassa in phytohormone-free BF liquid medium

Lin, T. C., Yamada, S., Wu, T. H. & Ishimaru, K., 2001, In : Chinese Pharmaceutical Journal. 53, 5, p. 225-232 8 p.

Research output: Contribution to journalArticle

Fragaria
Plant Growth Regulators
Polyphenols
Proanthocyanidins
Flavonoids
2000
37 Citations (Scopus)

The effect of steroid sulfatase inhibition on learning and spatial memory

Johnson, D. A., Wu, T. H., Li, P. K. & Maher, T. J., May 26 2000, In : Brain Research. 865, 2, p. 286-290 5 p.

Research output: Contribution to journalArticle

Steryl-Sulfatase
Scopolamine Hydrobromide
Learning
Amnesia
Tyramine
1998

Influence of different routes of administration on the cardiovascular effects of dihydrexidine (DHX) in rats

Wu, T. H., Locke, K. W., Loar, S. B. & Maher, T. J., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

Rats
Intranasal Administration
Arterial Pressure
Corpus Striatum
Oxidopamine
1996
1 Citation (Scopus)

Effects of salicylic acid on basal and amphetamine-induced striatal dop amine release: A microdialysis study

Wu, T. H., Acwonh, I. N. & Mäher, T. J., 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

amphetamine
Corpus Striatum
Salicylic Acid
Microdialysis
Amphetamine