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Research Output 2010 2019

  • 391 Citations
  • 11 h-Index
  • 27 Article
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Article
2019
2 Citations (Scopus)
Open Access
CCAAT-Enhancer-Binding Protein-delta
Platelet-Derived Growth Factor
Glioma
Stem Cells
Interleukin-1
3 Citations (Scopus)
temozolomide
Dehydroepiandrosterone
Glioblastoma
Acetylation
Phosphorylation
Embryonal Carcinoma Stem Cells
Neural Stem Cells
Zinc Fingers
Transcription
Zinc

Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis

Hung, C. Y., Hsu, T. I., Chuang, J. Y., Su, T. P., Chang, W. C. & Hung, J. J., Jan 1 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Astrocytes
Synapses
Hippocampus
Neurons
Toll-Like Receptor 2
2018
1 Citation (Scopus)

Ephexin1 is required for Eph-Mediated limb trajectory of spinal motor axons

Chang, C. J., Chang, M. Y., Chou, S. Y., Huang, C. C., Chuang, J. Y., Hsu, T. I., Chang, H. F., Wu, Y. H., Wu, C. C., Morales, D., Kania, A. & Kao, T. J., Feb 21 2018, In : Journal of Neuroscience. 38, 8, p. 2043-2056 14 p.

Research output: Contribution to journalArticle

Axons
Extremities
Ephrins
Growth Cones
Motor Neurons
6 Citations (Scopus)
Ubiquitination
Glioma
Glioblastoma
Stem Cells
temozolomide

Nck2 is essential for limb trajectory selection by spinal motor axons

Chang, C. J., Chang, M. Y., Lee, Y. C., Chen, K. Y., Hsu, T. I., Wu, Y. H., Chuang, J. Y. & Kao, T. J., Sep 1 2018, In : Developmental Dynamics. 247, 9, p. 1043-1056 14 p.

Research output: Contribution to journalArticle

Axons
Extremities
Motor Neurons
Ephrins
Neurites
4 Citations (Scopus)
Glioblastoma
Amyloid
Integrins
Serum
Glioma
1 Citation (Scopus)

Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress

Wu, C. C., Lee, P. T., Kao, T. J., Chou, S. Y., Su, R. Y., Lee, Y. C., Yeh, S. H., Liou, J. P., Hsu, T. I., Su, T. P., Chuang, C. K., Chang, W. C. & Chuang, J. Y., Oct 1 2018, In : Redox Biology. 19, p. 74-80 7 p.

Research output: Contribution to journalArticle

Acetylation
Oxidative stress
Zinc Fingers
Zinc
Oxidative Stress
7 Citations (Scopus)

USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy

Wang, Y. C., Wu, Y. S., Hung, C. Y., Wang, S. A., Young, M. J., Hsu, T. I. & Hung, J. J., Dec 1 2018, In : Nature Communications. 9, 1, 3996.

Research output: Contribution to journalArticle

Open Access
Tumor Microenvironment
Macrophages
Tumors
Interleukin-6
tumors
2017
12 Citations (Scopus)

Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase

Chang, K. Y., Hsu, T. I., Hsu, C. C., Tsai, S. Y., Liu, J. J., Chou, S. W., Liu, M. S., Liou, J. P., Ko, C. Y., Chen, K. Y., Hung, J. J., Chang, W. C., Chuang, C. K., Kao, T. J. & Chuang, J. Y., Oct 1 2017, In : Redox Biology. 13, p. 655-664 10 p.

Research output: Contribution to journalArticle

temozolomide
Methyltransferases
Glioblastoma
DNA
Proteins
3 Citations (Scopus)

Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma

Chang, K. Y., Huang, C. T., Hsu, T. I., Hsu, C. C., Liu, J. J., Chuang, C. K., Hung, J. J., Chang, W. C., Tsai, K. K. & Chuang, J. Y., Nov 4 2017, In : Biochemical and Biophysical Research Communications. 493, 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Glioblastoma
Gene expression
Chemical activation
temozolomide
temozolomide
Dehydroepiandrosterone
Glioma
Cytochrome P-450 Enzyme System
Up-Regulation
2016
10 Citations (Scopus)

Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

Hsu, T. I., Wang, Y. C., Hung, C. Y., Yu, C. H., Su, W. C., Chang, W. C. & Hung, J. J., Apr 12 2016, In : Oncotarget. 7, 15, p. 20840-20854 15 p.

Research output: Contribution to journalArticle

Interleukin-10
Lung Neoplasms
Neoplasms
Carcinogenesis
Lung
9 Citations (Scopus)

Suberoylanilide hydroxamic acid represses glioma stem-like cells

Hsu, C. C., Chang, W-C., Hsu, T-I., Liu, J. J., Yeh, S. H., Wang, J-Y., Liou, J-P., Ko, C-Y., Chang, K. Y. & Chuang, J-Y., Nov 18 2016, In : Journal of Biomedical Science. 23, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Glioma
Stem Cells
Glioblastoma
Cells
Histone Deacetylases
5 Citations (Scopus)

Variants of ubiquitin-specific peptidase 24 play a crucial role in lung cancer malignancy

Wang, Y. C., Wang, S. A., Chen, P. H., Hsu, T. I., Yang, W. B., Chuang, Y. P., Su, W. C., Liaw, H. J., Chang, W. C. & Hung, J. J., Jul 14 2016, In : Oncogene. 35, 28, p. 3669-3680 12 p.

Research output: Contribution to journalArticle

Ubiquitin
Lung Neoplasms
Peptide Hydrolases
Neoplasms
Single Nucleotide Polymorphism
2015
13 Citations (Scopus)

A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy

Hsu, T. I., Chen, Y. J., Hung, C. Y., Wang, Y. C., Lin, S. J., Su, W. C., Lai, M. D., Kim, S. Y., Wang, Q., Qian, K., Goto, M., Zhao, Y., Kashiwada, Y., Lee, K. H., Chang, W. C. & Hung, J. J., 2015, In : Oncotarget. 6, 15, p. 13671-13687 17 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Endoplasmic Reticulum Stress
Cyclin A2
Growth
Neoplasm Metastasis
21 Citations (Scopus)

MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy

Hsu, T. I., Lin, S. C., Lu, P. S., Chang, W-C., Hung, C. Y., Yeh, Y. M., Su, W. C., Liao, P. C. & Hung, J. J., Feb 12 2015, In : Oncogene. 34, 7, p. 826-837 12 p.

Research output: Contribution to journalArticle

Neoplasms
Lung Neoplasms
RNA Stability
nucleolin
Matrix Metalloproteinase 7
2014
49 Citations (Scopus)

MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo

Hsu, T. I., Hsu, C. H., Lee, K. H., Lin, J. T., Chen, C. S., Chang, K. C., Su, C. Y. J., Hsiao, M. & Lu, P. J., Jan 1 2014, In : Oncogenesis. 3, 4, e99.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
MicroRNAs
Prostatic Neoplasms
Carcinogenesis
Neoplasms
13 Citations (Scopus)

Nucleolin enhances internal ribosomal entry site (IRES)-mediated translation of Sp1 in tumorigenesis

Hung, C. Y., Yang, W. B., Wang, S. A., Hsu, T. I., Chang, W. C. & Hung, J. J., Aug 27 2014, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 12, p. 2843-2854 12 p.

Research output: Contribution to journalArticle

Protein Biosynthesis
Carcinogenesis
Proteins
5' Untranslated Regions
Growth Factor Receptors
17 Citations (Scopus)
Proteolysis
Lung Neoplasms
Carcinogenesis
Phosphorylation
Acetylation
50 Citations (Scopus)

Sp1-mediated microRNA-182 expression regulates lung cancer progression

Yang, W. B., Chen, P. H., Hsu, T. I., Fu, T. F., Su, W. C., Liaw, H., Chang, W. C. & Hung, J. J., 2014, In : Oncotarget. 5, 3, p. 740-753 14 p.

Research output: Contribution to journalArticle

MicroRNAs
Lung Neoplasms
Neoplasm Metastasis
Neoplasms
Growth
12 Citations (Scopus)
Telomerase
Cell Proliferation
Gene Expression
Proteins
human TERT protein
2012
41 Citations (Scopus)

Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of Sp1 to inhibit lung cancer growth

Hsu, T. I., Wang, M. C., Chen, S. Y., Huang, S. T., Yeh, Y. M., Su, W. C., Chang, W. C. & Hung, J. J., Dec 2012, In : Molecular Pharmacology. 82, 6, p. 1115-1128 14 p.

Research output: Contribution to journalArticle

Sumoylation
Lung Neoplasms
Growth
Proteins
Cyclin A2
78 Citations (Scopus)

Sp1 expression regulates lung tumor progression

Hsu, T. I., Wang, M. C., Chen, S. Y., Yeh, Y. M., Su, W. C., Chang, W. C. & Hung, J. J., Aug 30 2012, In : Oncogene. 31, 35, p. 3973-3988 16 p.

Research output: Contribution to journalArticle

Lung
Neoplasms
Proteins
Neoplasm Metastasis
Lung Neoplasms
2011
25 Citations (Scopus)

Heat shock protein 90 stabilizes nucleolin to increase mRNA stability in mitosis

Wang, S. A., Li, H. Y., Hsu, T. I., Chen, S. H., Wu, C. J., Chang, W. C. & Hung, J. J., Dec 23 2011, In : Journal of Biological Chemistry. 286, 51, p. 43816-43829 14 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
RNA Stability
Mitosis
Messenger RNA
Carcinogenesis
2010
9 Citations (Scopus)

Inhibition of LPS-induced C/EBPδ by trichostatin A has a positive effect on LPS-induced cyclooxygenase 2 expression in RAW264.7 cells

Liu, Y. W., Wang, S. A., Hsu, T. Y., Chen, T. A., Chang, W. C. & Hung, J. J., Aug 15 2010, In : Journal of Cellular Biochemistry. 110, 6, p. 1430-1438 9 p.

Research output: Contribution to journalArticle

trichostatin A
Cyclooxygenase 2
Lipopolysaccharides
Assays
Phosphorylation