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Research Output

  • 671 Citations
  • 16 h-Index
  • 39 Article
  • 3 Book
  • 1 Comment/debate
  • 1 Patent
2020

Dietary compound isoliquiritigenin, an antioxidant from licorice, suppresses triple-negative breast tumor growth via apoptotic death program activation in cell and xenograft animal models

Lin, P. H., Chiang, Y. F., Shieh, T. M., Chen, H. Y., Shih, C. K., Wang, T. H., Wang, K. L., Huang, T. C., Hong, Y. H., Li, S. C. & Hsia, S. M., Mar 10 2020, In : Antioxidants. 9, 3, 228.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation

Lin, P. H., Tung, Y. T., Chen, H. Y., Chiang, Y. F., Hong, H. C., Huang, K. C., Hsu, S. P., Huang, T. C. & Hsia, S. M., Jan 1 2020, In : Journal of Pineal Research. 68, 1, p. e12620 e12620.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019
Open Access
2 Citations (Scopus)

Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo

Chen, H-Y., Lin, P-H., Shih, Y-H., Wang, K-L., Hong, Y-H., Shieh, T-M., Huang, T-C. & Hsia, S-M., Apr 1 2019, In : Antioxidants. 8, 4, 99.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The expression profile and prognostic significance of metallothionein genes in colorectal cancer

Hung, K. C., Huang, T. C., Cheng, C. H., Cheng, Y. W., Lin, D. Y., Fan, J. J. & Lee, K. H., Aug 2 2019, In : International Journal of Molecular Sciences. 20, 16, 3849.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
2018

A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo

Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 205.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression

Chen, H. Y., Huang, T. C., Lin, L. C., Shieh, T. M., Wu, C. H., Wang, K. L., Hong, Y. H. & Hsia, S. M., Oct 1 2018, In : Cellular Physiology and Biochemistry. 49, 5, p. 1970-1986 17 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Manzamine a exerts anticancer activity against human colorectal cancer cells

Lin, L. C., Kuo, T. T., Chang, H. Y., Liu, W. S., Hsia, S. M. & Huang, T. C., Jul 29 2018, In : Marine Drugs. 16, 8, 252.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Protective Effect of Melatonin against Oxidative Stress-Induced Apoptosis and Enhanced Autophagy in Human Retinal Pigment Epithelium Cells

Chang, C. C., Huang, T. Y., Chen, H. Y., Huang, T. C., Lin, L. C., Chang, Y. J. & Hsia, S. M., Jan 1 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 9015765.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Roles of Fc domain and exudation in L2 antibody-mediated protection against human papillomavirus

Wang, J. W., Wu, W. H., Huang, T. C., Wong, M., Kwak, K., Ozato, K., Hung, C. F. & Roden, R. B. S., Aug 1 2018, In : Journal of Virology. 92, 15, e00572-18.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells

Huang, T. C., Lee, P. T., Wu, M. H., Huang, C. C., Ko, C. Y., Lee, Y. C., Lin, D. Y., Cheng, Y. W. & Lee, K. H., Aug 1 2017, In : PLoS One. 12, 8, e0181034.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Effects of Adlay Hull and Testa Ethanolic Extracts on the Growth of Uterine Leiomyoma Cells

Hsia, S-M., Lin, K-H., Chiang, W., Wu, C-H., Shieh, T-M., Huang, T-C., Chen, H-Y. & Lin, L-C., 2017, In : 調適醫學. 9, 2, p. 85-96 12 p.

Research output: Contribution to journalArticle

Isoliquiritigenin induces autophagy and inhibits ovarian cancer cell growth

Chen, H. Y., Huang, T. C., Shieh, T. M., Wu, C. H., Lin, L. C. & Hsia, S. M., Oct 1 2017, In : International Journal of Molecular Sciences. 18, 10, 2025.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Overexpression of miR-194 Reverses HMGA2-driven Signatures in Colorectal Cancer

Chang, H. Y., Ye, S. P., Pan, S. L., Kuo, T. T., Liu, B. C., Chen, Y. L. & Huang, T. C., 2017, In : Theranostics. 7, 16, p. 3889-3900 12 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Spontaneous and vaccine-induced clearance of Mus musculus papillomavirus 1 infection

Jiang, R. T., Wang, J. W., Peng, S., Huang, T. C., Wang, C., Cannella, F., Chang, Y. N., Viscidi, R. P., Best, S. R. A., Hung, C. F. & Roden, R. B. S., Aug 1 2017, In : Journal of Virology. 91, 15, e00699-17.

Research output: Contribution to journalArticle

13 Citations (Scopus)
10 Citations (Scopus)
2016

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

Wu, C-H., Chen, H. Y., Wang, C-W., Shieh, T. M., Huang, T-C., Lin, L. C., Wang, K. L. & Hsia, S-M., 2016, In : Oncotarget. 7, 45, p. 73432-73447 16 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Resveratrol inhibits proliferation of myometrial and leiomyoma cells and decreases extracellular matrix-associated protein expression

Wu, C. H., Shieh, T. M., Wei, L. H., Cheng, T. F., Chen, H. Y., Huang, T. C., Wang, K. L. & Hsia, S. M., May 1 2016, In : Journal of Functional Foods. 23, p. 241-252 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol

Sun, G., Cheng, Y. W., Lai, L., Huang, T. C., Wang, J., Wu, X., Wang, Y., Huang, Y., Wang, J., Zhang, K., Hu, S., Yang, J. R. & Yen, Y., 2016, In : Oncotarget. 7, 4, p. 3857-3872 16 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: Identification of functional disparities between azacytidine and decitabine

Hsieh, Y. Y., Huang, T. C., Lo, H. L., Jhan, J. Y., Chen, S. T. & Yang, P. M., May 10 2016, In : Oncotarget. 7, 19, p. 27363-27378 16 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2015

Quantitative proteomics reveals middle infrared radiation-interfered networks in breast cancer cells

Chang, H. Y., Li, M. H., Huang, T. C., Hsu, C. L., Tsai, S. R., Lee, S. C., Huang, H. C. & Juan, H. F., Feb 6 2015, In : Journal of Proteome Research. 14, 2, p. 1250-1262 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Quercetin, a main flavonoid in onion, inhibits the PGF-induced uterine contraction in vitro and in vivo

Wu, C. H., Shieh, T. M., Wang, K. L., Huang, T. C. & Hsia, S. M., Dec 1 2015, In : Journal of Functional Foods. 19, p. 495-504 10 p., 1300.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells

Chang, H. Y., Huang, T. C., Chen, N. N., Huang, H. C. & Juan, H. F., Jan 1 2014, In : Cell Death and Disease. 5, 11, e1540.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Radiation induces senescence and a bystander effect through metabolic alterations.

Liao, E. C., Hsu, Y. T., Chuah, Q. Y., Lee, Y. J., Hu, J. Y., Huang, T. C., Yang, P. M. & Chiu, S. J., 2014, In : Cell Death and Disease. 5

Research output: Contribution to journalArticle

41 Citations (Scopus)

The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS

Ting, C. H., Huang, H. N., Huang, T. C., Wu, C. J. & Chen, J. Y., Apr 2014, In : Biomaterials. 35, 11, p. 3627-3640 14 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2013

Flow Cytometric Detection of Mitochondrial Membrane Potential

Chang, H-Y., Huang, H-C., Huang, T-C., Yang, P-C., Wang, Y-C. & Juan, H-F., Jan 1 2013

Research output: Book/ReportBook

Flow Cytometric Detection of Reactive Oxygen Species

Chang, H-Y., Huang, H-C., Huang, T-C., Yang, P-C., Wang, Y-C. & Juan, H-F., Jan 1 2013

Research output: Book/ReportBook

20 Citations (Scopus)

Proteomic and functional analysis of zebrafish after administration of antimicrobial peptide epinecidin-1

Huang, T. C. & Chen, J. Y., Feb 2013, In : Fish and Shellfish Immunology. 34, 2, p. 593-598 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2012

Ectopic ATP synthase blockade suppresses lung adenocarcinoma growth by activating the unfolded protein response

Chang, H. Y., Huang, H. C., Huang, T. C., Yang, P. C., Wang, Y. C. & Juan, H. F., Sep 15 2012, In : Cancer Research. 72, 18, p. 4696-4706 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Erratum: Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR (FEBS Letters (2011) 585 (3582-3586))

Huang, T. C., Chang, H. Y., Chen, C. Y., Wu, P. Y., Lee, H., Liao, Y. F., Hsu, W. M., Huang, H. C. & Juan, H. F., Jan 2 2012, In : FEBS Letters. 586, 1, p. 107 1 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Pardaxin, a fish antimicrobial peptide, exhibits antitumor activity toward murine fibrosarcoma in Vitro and in Vivo

Wu, S. P., Huang, T. C., Lin, C. C., Hui, C. F., Lin, C. H. & Chen, J. Y., Aug 2012, In : Marine Drugs. 10, 8, p. 1852-1872 21 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Piscidin-1, an antimicrobial peptide from fish (Hybrid Striped Bass Morone saxatilis x M. chrysops), induces apoptotic and necrotic activity in HT1080 cells

Lin, H. J., Huang, T. C., Muthusamy, S., Lee, J. F., Duann, Y. F. & Lin, C. H., May 2012, In : Zoological Science. 29, 5, p. 327-332 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

耐受醇類之大腸桿菌及其製備方法

H, M., Chang, H-Y., Huang, H-C., Huang, T-C., Liao, J-C. & Juan, H-F., 2012

Research output: Patent

2011

Pardaxin, an antimicrobial peptide, triggers caspase-dependent and ROS-mediated apoptosis in HT-1080 cells

Huang, T. C., Lee, J. F. & Chen, J. Y., Oct 2011, In : Marine Drugs. 9, 10, p. 1995-2009 15 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR

Huang, T. C., Chang, H. Y., Chen, C. Y., Wu, P. Y., Lee, H., Liao, Y. F., Hsu, W. M., Huang, H. C. & Juan, H. F., Nov 16 2011, In : FEBS Letters. 585, 22, p. 3582-3586 5 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

The effect of narrow bandwidth infrared radiation on the growth of Escherichia coli

Tsai, S. R., Huang, T. C., Liang, C. M., Chang, H. Y., Chang, Y. T., Huang, H. C., Juan, H. F. & Lee, S. C., Oct 17 2011, In : Applied Physics Letters. 99, 16, 163704.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2008

Targeting therapy for breast carcinoma by ATP synthase inhibitor aurovertin b

Huang, T. C., Chang, H. Y., Hsu, C. H., Kuo, W. H., Chang, K. J. & Juan, H. F., Apr 2008, In : Journal of Proteome Research. 7, 4, p. 1433-1444 12 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)
2007

An apoptosis-related gene network induced by novel compound-cRGD in human breast cancer cells

Huang, T. C., Huang, H. C., Chang, C. C., Chang, H. Y., Ou, C. H., Hsu, C. H., Chen, S. T. & Juan, H. F., Jul 24 2007, In : FEBS Letters. 581, 18, p. 3517-3522 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2006

Proteomics analysis of a novel compound: Cyclic RGD in breast carcinoma cell line MCF-7

Juan, H. F., Wang, I. H., Huang, T. C., Li, J. J., Chen, S. T. & Huang, H. C., May 2006, In : Proteomics. 6, 10, p. 2991-3000 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)