TH Alexander Wu

Personal profile

Education

2005 Ph.D. (Anatomy and Cell Biology), Queen's University, Kingston, Ontario, Canada

Experience

2013- Associate Professor, Taipei Medical University
2008-2013 Assoistant Professor, Taipei Medical University
2010 Visiting scholar to Dr. Andrew Kung’s lab at Dana Farber Cancer Institute

Research Interests

Molecular Biology
Preclinical mouse tumor models
Small animal imaging
Cancer stem cell research
Translational medicine

URL

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Neoplastic Stem Cells Medicine & Life Sciences

Neoplasms Medicine & Life Sciences

Catenins Medicine & Life Sciences

Antrodia Medicine & Life Sciences

Carcinogenesis Medicine & Life Sciences

MicroRNAs Medicine & Life Sciences

Lung Neoplasms Medicine & Life Sciences

Neoplasm Metastasis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2010 2016

13 Finished

The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells (I)

Yen, Y., Cheng, T. & Wu, T. A.

8/1/15 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

Study of Expression and Functional Mechanisms of Histamine N-Methyltransferase (HNMT) in Tumorigenesis and Correlation with Progression in Lung Cancer

Wang, L., Lee, W., Ho, Y. & Wu, T. A.

8/1/15 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

臨床前FGFR抑制劑對於抗藥性胰臟癌療效之評估

Wu, T. A.

5/1/15 → 4/30/16

Project: C - Project of Alliance › t - Taipei Medical University Shuang Ho Hospital

探討LncRNA MALAT1 在惡性乳癌幹細胞生成之角色以及pterostilbene 對於透過抑制MALAT1而抑制乳癌幹細胞功能之研究

Wu, T. A.

6/1/14 → 5/31/15

Project: C - Project of Alliance › t - Taipei Medical University Shuang Ho Hospital

探討樟芝萃取物antrocin在抑制大直腸癌細胞轉移的效用及機制

Wu, T. A.

3/1/13 → 2/28/14

Project: C - Project of Alliance › n - Chi Mei Medical Center

Research Output 2003 2019

1582 Citations
21 h-Index
76 Article
2 Comment/debate
1 Review article

A novel multi-target small molecule, LCC-09, inhibits stemness and therapy-resistant phenotypes of glioblastoma cells by increasing MIR-34a and deregulating the DRD4/AKT/MTOR signaling axis

Wen, Y. T., Wu, A. T., Bamodu, O. A., Wei, L., Lin, C. M., Yen, Y., Chao, T. Y., Mukhopadhyay, D., Hsiao, M. & Huang, H. S., Oct 1 2019, In : Cancers. 11, 10, 1442.

Research output: Contribution to journal › Article

Open Access

temozolomide

Glioblastoma

Phenotype

Glioma

Stem Cells

1 Citation (Scopus)

Antrocin, a bioactive component from Antrodia cinnamomea, suppresses breast carcinogenesis and stemness via downregulation of β-catenin/Notch1/Akt signaling

Chen, J. H., T.H Wu, A., T.W Tzeng, D., Huang, C. C., Tzeng, Y. M. & Chao, T. Y., Jan 1 2019, In : Phytomedicine. 52, p. 70-78 9 p.

Research output: Contribution to journal › Article

Antrodia

Catenins

Carcinogenesis

Breast

Down-Regulation

1 Citation (Scopus)

Antrodia cinnamomea enhances chemo-sensitivity of 5-fu and suppresses colon tumorigenesis and cancer stemness via up-regulation of tumor suppressor miR-142-3p

Huang, Y. J., Yadav, V. K., Srivastava, P., Wu, A. T. H., Huynh, T. T., Wei, P. L., Huang, C. Y. F. & Huang, T. H., Aug 1 2019, In : Biomolecules. 9, 8, 306.

Research output: Contribution to journal › Article

Open Access

Antrodia

Fluorouracil

Colonic Neoplasms

Tumors

Carcinogenesis

1 Citation (Scopus)

Astragalus polysaccharides (PG2) Enhances the M1 Polarization of Macrophages, Functional Maturation of Dendritic Cells, and T Cell-Mediated Anticancer Immune Responses in Patients with Lung Cancer

Bamodu, O. A., Kuo, K. T., Wang, C. H., Huang, W. C., Wu, A. T. H., Tsai, J. T., Lee, K. Y., Yeh, C. T. & Wang, L. S., Sep 20 2019, In : Nutrients. 11, 10

Research output: Contribution to journal › Article

Open Access

Astragalus

dendritic cells

lung neoplasms

Dendritic Cells

Polysaccharides

ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients

Huang, Y-J., Jan, Y-H., Chang, Y-C., Tsai, H-F., Wu, A. T., Chen, C-L. & Hsiao, M., Jul 21 2019, In : Journal of Clinical Medicine. 8, 7

Research output: Contribution to journal › Article

AMP-Activated Protein Kinases

Epithelial-Mesenchymal Transition

Hypoxia-Inducible Factor 1

Colonic Neoplasms

Colorectal Neoplasms