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TH Alexander Wu

Associate Professor

 https://orcid.org/0000-0002-0178-6530
  • 1636 Citations
  • 21 h-Index
20032019
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Personal profile

Education

  • 2005 Ph.D. (Anatomy and Cell Biology), Queen's University, Kingston, Ontario, Canada

Experience

  • 2013- Associate Professor, Taipei Medical University
  • 2008-2013 Assoistant Professor, Taipei Medical University
  • 2010 Visiting scholar to Dr. Andrew Kung’s lab at Dana Farber Cancer Institute

Research Interests

  • Molecular Biology
  • Preclinical mouse tumor models
  • Small animal imaging
  • Cancer stem cell research
  • Translational medicine

URL

Fingerprint Dive into the research topics where TH Alexander Wu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 84 Similar Profiles
Neoplastic Stem Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Catenins Medicine & Life Sciences
Antrodia Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Lung Neoplasms Medicine & Life Sciences
Neoplasm Metastasis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2010 2016

The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells (I)

Yen, Y., Cheng, T. & Wu, T. A.

8/1/15 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

Study of Expression and Functional Mechanisms of Histamine N-Methyltransferase (HNMT) in Tumorigenesis and Correlation with Progression in Lung Cancer

Wang, L., Lee, W., Ho, Y. & Wu, T. A.

8/1/15 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

臨床前FGFR抑制劑對於抗藥性胰臟癌療效之評估

Wu, T. A.

5/1/15 → 4/30/16

Project: C - Project of Alliance › t - Taipei Medical University Shuang Ho Hospital

探討LncRNA MALAT1 在惡性乳癌幹細胞生成之角色以及pterostilbene 對於透過抑制MALAT1而抑制乳癌幹細胞功能之研究

Wu, T. A.

6/1/14 → 5/31/15

Project: C - Project of Alliance › t - Taipei Medical University Shuang Ho Hospital

探討樟芝萃取物antrocin在抑制大直腸癌細胞轉移的效用及機制

Wu, T. A.

3/1/13 → 2/28/14

Project: C - Project of Alliance › n - Chi Mei Medical Center

Research Output 2003 2019

  • 1636 Citations
  • 21 h-Index
  • 76 Article
  • 2 Comment/debate
  • 1 Review article

A novel multi-target small molecule, LCC-09, inhibits stemness and therapy-resistant phenotypes of glioblastoma cells by increasing MIR-34a and deregulating the DRD4/AKT/MTOR signaling axis

Wen, Y. T., Wu, A. T., Bamodu, O. A., Wei, L., Lin, C. M., Yen, Y., Chao, T. Y., Mukhopadhyay, D., Hsiao, M. & Huang, H. S., Oct 1 2019, In : Cancers. 11, 10, 1442.

Research output: Contribution to journal › Article

Open Access
temozolomide
Glioblastoma
Phenotype
Glioma
Stem Cells
1 Citation (Scopus)

Antrocin, a bioactive component from Antrodia cinnamomea, suppresses breast carcinogenesis and stemness via downregulation of β-catenin/Notch1/Akt signaling

Chen, J. H., T.H Wu, A., T.W Tzeng, D., Huang, C. C., Tzeng, Y. M. & Chao, T. Y., Jan 1 2019, In : Phytomedicine. 52, p. 70-78 9 p.

Research output: Contribution to journal › Article

Antrodia
Catenins
Carcinogenesis
Breast
Down-Regulation
1 Citation (Scopus)

Antrodia cinnamomea enhances chemo-sensitivity of 5-fu and suppresses colon tumorigenesis and cancer stemness via up-regulation of tumor suppressor miR-142-3p

Huang, Y. J., Yadav, V. K., Srivastava, P., Wu, A. T. H., Huynh, T. T., Wei, P. L., Huang, C. Y. F. & Huang, T. H., Aug 1 2019, In : Biomolecules. 9, 8, 306.

Research output: Contribution to journal › Article

Open Access
Antrodia
Fluorouracil
Colonic Neoplasms
Tumors
Carcinogenesis
1 Citation (Scopus)

Astragalus polysaccharides (PG2) Enhances the M1 Polarization of Macrophages, Functional Maturation of Dendritic Cells, and T Cell-Mediated Anticancer Immune Responses in Patients with Lung Cancer

Bamodu, O. A., Kuo, K. T., Wang, C. H., Huang, W. C., Wu, A. T. H., Tsai, J. T., Lee, K. Y., Yeh, C. T. & Wang, L. S., Sep 20 2019, In : Nutrients. 11, 10

Research output: Contribution to journal › Article

Open Access
Astragalus
dendritic cells
lung neoplasms
Dendritic Cells
Polysaccharides

ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients

Huang, Y-J., Jan, Y-H., Chang, Y-C., Tsai, H-F., Wu, A. T., Chen, C-L. & Hsiao, M., Jul 21 2019, In : Journal of Clinical Medicine. 8, 7

Research output: Contribution to journal › Article

AMP-Activated Protein Kinases
Epithelial-Mesenchymal Transition
Hypoxia-Inducible Factor 1
Colonic Neoplasms
Colorectal Neoplasms