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TH Alexander Wu

Associate Professor

 https://orcid.org/0000-0002-0178-6530
  • 1927 Citations
  • 24 h-Index
20032020

Research output per year

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Personal profile

Education

  • 2005 Ph.D. (Anatomy and Cell Biology), Queen's University, Kingston, Ontario, Canada
  • 1997 B.S.(Biochemistry), Queen's University, Kingston, Ontario, Canada

Experience

  • 2019- Associate Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
  • 2013- Associate Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University
  • 2012-2013 Assistant Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University
  • 2008-2012 Assoistant Professor, Department of Radiology, Taipei Medical University
  • 2010 Visiting scholar to Dr. Andrew Kung’s lab at Dana Farber Cancer Institute

Research Interests

  • Molecular Biology
  • Preclinical mouse tumor models
  • Small animal imaging
  • Cancer stem cell research
  • Translational medicine

URL

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Projects

The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells (I)

Yen, Y., Cheng, T. & Wu, T. A.

8/1/15 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

Study of Expression and Functional Mechanisms of Histamine N-Methyltransferase (HNMT) in Tumorigenesis and Correlation with Progression in Lung Cancer

Wang, L., Lee, W., Ho, Y. & Wu, T. A.

8/1/15 → 7/31/16

Project: A - Government Institution › b - Ministry of Science and Technology

臨床前FGFR抑制劑對於抗藥性胰臟癌療效之評估

Wu, T. A.

5/1/15 → 4/30/16

Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

探討LncRNA MALAT1 在惡性乳癌幹細胞生成之角色以及pterostilbene 對於透過抑制MALAT1而抑制乳癌幹細胞功能之研究

Wu, T. A.

6/1/14 → 5/31/15

Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

探討樟芝萃取物antrocin在抑制大直腸癌細胞轉移的效用及機制

Wu, T. A.

3/1/13 → 2/28/14

Project: C - Project of Alliance › o - Chi Mei Medical Center

Research Output

  • 1927 Citations
  • 24 h-Index
  • 85 Article
  • 2 Comment/debate
  • 1 Review article

Assessment of Predictive Scoring System for 90-Day Mortality Among Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Who Have Completed Concurrent Chemoradiotherapy

Lin, K. C., Chen, T. M., Yuan, K. S. P., Wu, A. T. H. & Wu, S. Y., Mar 2 2020, In : JAMA network open. 3, 3, p. e1920671

Research output: Contribution to journal › Article

Open Access

    • Outcomes of adjuvant oral versus intravenous fluoropyrimidines for high-risk stage II or stage III colon adenocarcinoma: A propensity score-matched, nationwide, population-based cohort study

    Zhang, J., Yen, Y. C., Qin, L., Chang, C. L., Yuan, K. S. P., Wu, A. T. H. & Wu, S. Y., Jan 1 2020, In : Journal of Cancer. 11, 14, p. 4157-4165 9 p.

    Research output: Contribution to journal › Article

    Open Access

    • Ovatodiolide, isolated from Anisomeles indica, suppresses bladder carcinogenesis through suppression of mTOR/β-catenin/CDK6 and exosomal miR-21 derived from M2 tumor-associated macrophages

    Wu, A. T. H., Srivastava, P., Yadav, V. K., Tzeng, D. T. W., Iamsaard, S., Su, E. C. Y., Hsiao, M. & Liu, M. C., Aug 15 2020, In : Toxicology and Applied Pharmacology. 401, 115109.

    Research output: Contribution to journal › Article

    • Ovatodiolide suppresses oral cancer malignancy by down-regulating exosomal mir-21/STAT3/β-catenin cargo and preventing oncogenic transformation of normal gingival fibroblasts

    Chen, J. H., Wu, A. T. H., Bamodu, O. A., Yadav, V. K., Chao, T. Y., Tzeng, Y. M., Mukhopadhyay, D., Hsiao, M. & Lee, J. C., Jan 2020, In : Cancers. 12, 1, 56.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Citation (Scopus)

    Preclinical evaluation of the novel small-molecule msi-n1014 for treating drug-resistant colon cancer via the lgr5/β-catenin/mir-142-3p network and reducing cancer-associated fibroblast transformation

    Yadav, V. K., Huang, Y. J., George, T. A., Wei, P. L., Sumitra, M. R., Ho, C. L., Chang, T. H., Wu, A. T. H. & Huang, H. S., Jun 2020, In : Cancers. 12, 6, p. 1-15 15 p., 1590.

    Research output: Contribution to journal › Article

    Open Access