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Research Output 1989 2019

  • 1556 Citations
  • 20 h-Index
  • 76 Article
  • 2 Comment/debate
  • 1 Book
  • 1 Erratum
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Article
2019
Single-Chain Antibodies
Epitopes
Escherichia coli
Amino Acids
OMPA outer membrane proteins

Cardamonin Induces Cell Cycle Arrest, Apoptosis and Alters Apoptosis Associated Gene Expression in WEHI-3 Mouse Leukemia Cells

Liao, N-C., Shih, Y-L., Chou, J-S., Chen, K-W., Chen, Y-L., Lee, M-H., Peng, S-F., Leu, S-J. & Chung, J-G., Apr 25 2019, In : The American journal of Chinese medicine. p. 1-22 22 p.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Leukemia
Apoptosis
Gene Expression
Apoptosis Regulatory Proteins
2018
11 Citations (Scopus)

A comparison study of SiO2/nano metal oxide composite sphere for antibacterial application

Hou, Y. X., Abdullah, H., Kuo, D. H., Leu, S. J., Gultom, N. S. & Su, C. H., Jan 15 2018, In : Composites Part B: Engineering. 133, p. 166-176 11 p.

Research output: Contribution to journalArticle

Oxides
Metals
Composite materials
Nanoparticles
Light emitting diodes

Characterization of chicken-derived single chain antibody fragments against venom of Naja naja atra

Lee, C. H., Leu, S. J., Lee, Y. C., Liu, C. I., Lin, L. T., Mwale, P. F., Chiang, J. R., Tsai, B. Y., Chen, C. C., Hung, C. S. & Yang, Y. Y., Oct 1 2018, In : Toxins. 10, 10, 383.

Research output: Contribution to journalArticle

Cobra Venoms
Elapidae
Single-Chain Antibodies
Immunoglobulin Fragments
Venoms
3 Citations (Scopus)
Anti-Allergic Agents
Dendritic Cells
Asthma
Ligands
Th1 Cells
2017

Effects of Porphyromonas gingivalis on Titanium Surface by Different Clinical Treatment

Batsukh, N., Feng, S. W., Lee, W. F., Leu, S. J., Tsai, P. Y., Ho, K. N., Lin, C. T., Su, C. H. & Chang, W. J., Feb 1 2017, In : Journal of Medical and Biological Engineering. 37, 1, p. 35-44 10 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Titanium
Chlorhexidine
Biofilms
Lasers
8 Citations (Scopus)

Metal oxide composite thin films made by magnetron sputtering for bactericidal application

Chuang, K. T., Abdullah, H., Leu, S. J., Cheng, K. B., Kuo, D. H., Chen, H. C., Chien, J. H. & Hu, W. T., Mar 15 2017, In : Journal of Photochemistry and Photobiology A: Chemistry. 337, p. 151-164 14 p.

Research output: Contribution to journalArticle

Composite films
Magnetron sputtering
Oxides
metal oxides
magnetron sputtering
4 Citations (Scopus)

Single chain antibody fragment against venom from the snake Daboia russelii formosensis

Lee, C. H., Lee, Y. C., Lee, Y. L., Leu, S. J., Lin, L. T., Chen, C. C., Chiang, J. R., Fellow, P., Tsai, B. Y., Hung, C. S. & Yang, Y. Y., Nov 1 2017, In : Toxins. 9, 11, 347.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Immunoglobulin Fragments
Snake Venoms
Venoms
Bacteriophages
10 Citations (Scopus)

Valproic Acid and Lithium Meditate Anti-Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

Leu, S. J., Yang, Y. Y., Liu, H. C., Cheng, C. Y., Wu, Y. C., Huang, M. C., Lee, Y. L., Chen, C. C., Shen, W. W. & Liu, K. J., May 1 2017, In : Journal of Cellular Physiology. 232, 5, p. 1176-1186 11 p.

Research output: Contribution to journalArticle

Valproic Acid
Lithium
Dendritic Cells
Cell Differentiation
Anti-Inflammatory Agents
2016
11 Citations (Scopus)

Antibodies against venom of the snake Deinagkistrodon acutus

Lee, C. H., Lee, Y. C., Liang, M. H., Leu, S. J., Lin, L. T., Chiang, J. R. & Yang, Y. Y., 2016, In : Applied and Environmental Microbiology. 82, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

venom
Snake Venoms
venoms
snake
snakes
11 Citations (Scopus)

Cordyceps militaris treatment preserves renal function in type 2 diabetic nephropathy mice

Yu, S. H., Dubey, N. K., Li, W. S., Liu, M. C., Chiang, H. S., Leu, S. J., Shieh, Y. H., Tsai, F. C. & Deng, W. P., Nov 1 2016, In : PLoS One. 11, 11, e0166342.

Research output: Contribution to journalArticle

Cordyceps militaris
Cordyceps
diabetic nephropathy
Diabetic Nephropathies
renal function
9 Citations (Scopus)

Production and characterization of neutralizing antibodies against Bungarus multicinctus snake venom

Lee, C. H., Lee, Y-C., Leu, S-J., Lin, L-T., Chiang, J. R., Hsu, W. J. & Yang, Y-Y., 2016, In : Applied and Environmental Microbiology. 82, 23, p. 6973-6982 10 p.

Research output: Contribution to journalArticle

Bungarus
venom
Single-Chain Antibodies
Snake Venoms
venoms
2015
12 Citations (Scopus)
ferulic acid
Dendritic Cells
Inflammation
Cytokines
Anti-Allergic Agents
9 Citations (Scopus)

Hypoglycemic Activity through a Novel Combination of Fruiting Body and Mycelia of Cordyceps militaris in High-Fat Diet-Induced Type 2 Diabetes Mellitus Mice

Yu, S. H., Chen, S. Y. T., Li, W. S., Dubey, N. K., Chen, W. H., Chuu, J. J., Leu, S. J. & Deng, W. P., 2015, In : Journal of Diabetes Research. 2015, 723190.

Research output: Contribution to journalArticle

Cordyceps
Mycelium
High Fat Diet
Hypoglycemic Agents
Type 2 Diabetes Mellitus
10 Citations (Scopus)

Phage display - Mediated discovery of novel tyrosinase-targeting tetrapeptide inhibitors reveals the significance of N-terminal preference of cysteine residues and their functional sulfur atom

Lee, Y-C., Hsiao, N-W., Tseng, T-S., Chen, W-C., Lin, H-H., Leu, S. J., Yang, E-W. & Tsai, K-C., Jan 1 2015, In : Molecular Pharmacology. 87, 2, p. 218-230 13 p., A8.

Research output: Contribution to journalArticle

Monophenol Monooxygenase
Sulfur
Bacteriophages
Cysteine
Agaricales
2 Citations (Scopus)

Single chain antibody fragment with serine protease inhibitory property capable of neutralizing toxicity of Trimeresurus mucrosquamatus venom

Lee, Y. C., Chen, W. C., Liang, M. H., Lee, C. H., Tsai, K. C., Chiang, J. R., Chiang, L. C., Chen, C. C., Chang, C. Y., Lee, C. H., Leu, S. J. & Yang, Y. Y., May 1 2015, In : Biochemical and Biophysical Research Communications. 460, 2, p. 170-176 7 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Immunoglobulin Fragments
Serine Proteases
Toxicity
Snake Bites
2013
9 Citations (Scopus)

Associations between genetic polymorphisms of paraoxonase genes and coronary artery disease in a Taiwanese population

Chen, C. C., Chen, C. C., Tu, J. D., Wu, Y. L. & Leu, S. J., Nov 2013, In : Clinical Biochemistry. 46, 16-17, p. 1664-1667 4 p.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Genetic Polymorphisms
Polymorphism
Coronary Artery Disease
Genes
4 Citations (Scopus)

Isolation, characterization, and molecular modeling of a rheumatoid factor from a hepatitis C virus infected patient with sjögren's syndrome

Lee, Y. C., Tsai, K. C., Leu, S. J., Wang, T. J., Liu, C. Y. & Yang, Y. Y., 2013, In : Scientific World Journal. 2013, 516516.

Research output: Contribution to journalArticle

hepatitis
Molecular modeling
Rheumatoid Factor
complementarity
Viruses
9 Citations (Scopus)

Notch Ligand Delta-Like 4-Pretreated Dendritic Cells Alleviate Allergic Airway Responses by Enhancing IL-10 Production

Huang, H. M., Hsiao, G., Fan, C. K., Lin, C. L., Leu, S. J., Chiang, B. L. & Lee, Y. L., May 16 2013, In : PLoS One. 8, 5, e63613.

Research output: Contribution to journalArticle

dendritic cells
interleukin-10
Interleukin-10
Dendritic Cells
ovalbumin
12 Citations (Scopus)
Regulatory T-Lymphocytes
Immunosuppressive Agents
Blood Platelets
Asthma
T-Lymphocytes
2012
18 Citations (Scopus)

Diverse effects of type II collagen on osteogenic and adipogenic differentiation of mesenchymal stem cells

Chiu, L. H., Tsai, T-S., Huang, H. M., Leu, S. J., Yang, C. B. & Tsai, Y-H., Jun 2012, In : Journal of Cellular Physiology. 227, 6, p. 2412-2420 9 p.

Research output: Contribution to journalArticle

Collagen Type II
Stem cells
Mesenchymal Stromal Cells
Integrins
Adipogenesis
6 Citations (Scopus)

Roles of Glycogen Synthase Kinase-3 in Alzheimer's Disease: From Pathology to Treatment Target

Liu, H. C., Leu, S. J. & Chuang, D. M., Jun 2012, In : Journal of Experimental and Clinical Medicine(Taiwan). 4, 3, p. 135-139 5 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Alzheimer Disease
Pathology
Neurofibrillary Tangles
Amyloid
2011
7 Citations (Scopus)

Carbon tetrachloride-induced hepatotoxicity and its amelioration by Agaricus blazei Murrill extract in a mouse model

Chang, J. B., Wu, M. F., Yang, Y. Y., Leu, S. J., Chen, Y. L., Yu, C. S., Yu, C. C., Chang, S. J., Lu, H. F. & Chung, J. G., Nov 2011, In : In Vivo. 25, 6, p. 971-976 6 p.

Research output: Contribution to journalArticle

Agaricus
Carbon Tetrachloride
Aspartate Aminotransferases
Alanine Transaminase
Glutathione Peroxidase
33 Citations (Scopus)
Alcohol Withdrawal Delirium
Brain-Derived Neurotrophic Factor
Alcoholics
Alcohols
Serum
14 Citations (Scopus)

Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer

Charoenfuprasert, S., Yang, Y. Y., Lee, Y. C., Chao, K. C., Chu, P. Y., Lai, C. R., Hsu, K. F., Chang, K. C., Chen, Y. C., Chen, L. T., Chang, J. Y., Leu, S. J. & Shih, N. Y., Aug 18 2011, In : Oncogene. 30, 33, p. 3570-3584 15 p.

Research output: Contribution to journalArticle

Neoplasm Antigens
Ovarian Neoplasms
Carcinogenesis
Phosphotransferases
Salts
20 Citations (Scopus)

Modulation of the development of human monocyte-derived dendritic cells by lithium chloride

Liu, K. J., Lee, Y. L., Yang, Y. Y., Shih, N. Y., Ho, C. C., Wu, Y. C., Huang, T. S., Huang, M. C., Liu, H. C., Shen, W. W. & Leu, S. J., Feb 2011, In : Journal of Cellular Physiology. 226, 2, p. 424-433 10 p.

Research output: Contribution to journalArticle

Lithium Chloride
Human Development
Dendritic Cells
Monocytes
Modulation
8 Citations (Scopus)
Monocytes
Protein Isoforms
Acetates
Chemical activation
Apoptosis
14 Citations (Scopus)

The immuno-regulatory effects of Schisandra chinensis and its constituents on human monocytic leukemia cells

Lin, R. D., Mao, Y. W., Leu, S. J., Huang, C. Y. & Lee, M. H., Jun 2011, In : Molecules. 16, 6, p. 4836-4849 14 p.

Research output: Contribution to journalArticle

Schisandra
Macrophage Inflammatory Proteins
macrophages
leukemias
Granulocyte-Macrophage Colony-Stimulating Factor
2010
17 Citations (Scopus)

Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma

Liu, K. J., Leu, S. J., Su, C. H., Chiang, B. L., Chen, Y. L. & Lee, Y. L., Mar 2010, In : Immunology. 129, 3, p. 351-362 12 p.

Research output: Contribution to journalArticle

Antrodia
Ovalbumin
Allergens
Dendritic Cells
Polysaccharides
16 Citations (Scopus)

CC-chemokine ligand 18/pulmonary activation-regulated chemokine expression in the CNS with special reference to traumatic brain injuries and neoplastic disorders

Chang, C. Y., Lee, Y. H., Leu, S. J., Wang, C. Y., Wei, C. P., Hung, K. S., Pai, M. H., Tsai, M. D. & Wu, C. H., Feb 17 2010, In : Neuroscience. 165, 4, p. 1233-1243 11 p.

Research output: Contribution to journalArticle

CC Chemokines
Chemokines
Ligands
Lung
Glioblastoma
13 Citations (Scopus)

Cytokine gene-modulated dendritic cells protect against allergic airway inflammation by inducing IL-10+ IFN-γ CD4+ T cells

Hsu, C. Y., Leu, S. J., Chiang, B. L., Liu, H. E., Su, H. C. & Lee, Y. L., Aug 2010, In : Gene Therapy. 17, 8, p. 1011-1021 11 p.

Research output: Contribution to journalArticle

Interleukin-10
Dendritic Cells
Interferons
Cytokines
Inflammation
9 Citations (Scopus)

Generation and characterization of anti-α-enolase single-chain antibodies in chicken

Leu, S. J., Lee, Y. C., Shih, N. Y., Huang, I. J., Liu, K. J., Lu, H. F., Huang, S. Y. & Yang, Y. Y., Oct 2010, In : Veterinary Immunology and Immunopathology. 137, 3-4, p. 251-260 10 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
phosphopyruvate hydratase
Phosphopyruvate Hydratase
Chickens
chickens
3 Citations (Scopus)

Identification of a new peptide for fibrosarcoma tumor targeting and imaging in vivo

Wu, C. C., Lin, E. H., Lee, Y. C., Tai, C. J., Kuo, T. H., Wang, H. E., Luo, T. Y., Fu, Y. K., Chen, H. J., Sun, M. D., Wu, C. H., Wu, C. W., Leu, S. J. & Deng, W. P., 2010, In : Journal of Biomedicine and Biotechnology. 2010, 167045.

Research output: Contribution to journalArticle

Fibrosarcoma
Tumors
Bacteriophages
Imaging techniques
Peptides
58 Citations (Scopus)

Increased expression of enolase α in human breast cancer confers tamoxifen resistance in human breast cancer cells

Tu, S. H., Chang, C. C., Chen, C. S., Tam, K. W., Wang, Y. J., Lee, C. H., Lin, H. W., Cheng, T. C., Huang, C. S., Chu, J. S., Shih, N. Y., Chen, L. C., Leu, S. J., Ho, Y. S. & Wu, C. H., Jun 2010, In : Breast Cancer Research and Treatment. 121, 3, p. 539-553 15 p.

Research output: Contribution to journalArticle

Phosphopyruvate Hydratase
Tamoxifen
Breast Neoplasms
Neoplasms
Messenger RNA
16 Citations (Scopus)

MBP-1 is efficiently encoded by an alternative transcript of the ENO1 gene but post-translationally regulated by proteasome-dependent protein turnover

Lung, J., Liu, K. J., Chang, J. Y., Leu, S. J. & Shih, N. Y., 2010, In : FEBS Journal. 277, 20, p. 4308-4321 14 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Carrier Proteins
Genes
Proteins
Cell Fractionation
47 Citations (Scopus)

Reduced expression of circadian clock genes in male alcoholic patients

Huang, M. C., Ho, C. W., Chen, C. H., Liu, S. C., Chen, C. C. & Leu, S. J., Nov 2010, In : Alcoholism: Clinical and Experimental Research. 34, 11, p. 1899-1904 6 p.

Research output: Contribution to journalArticle

Circadian Clocks
Alcoholics
Clocks
Alcohol Withdrawal Delirium
Alcoholism
11 Citations (Scopus)
Therapeutic Uses
Interleukin-12
Adenoviridae
Genetic Therapy
Interleukin-10
2009
14 Citations (Scopus)

OmpA is the critical component for escherichia coli invasion-induced astrocyte activation

Wu, H. H., Yang, Y. Y., Hsieh, W. S., Lee, C. H., Leu, S. J. C. & Chen, M. R., Jun 2009, In : Journal of Neuropathology and Experimental Neurology. 68, 6, p. 677-690 14 p.

Research output: Contribution to journalArticle

Astrocytes
Escherichia coli
Escherichia coli Meningitis
OMPA outer membrane proteins
1-Phosphatidylinositol 4-Kinase
8 Citations (Scopus)

Reduction of monocyte chemoattractant protein-1 and interleukin-8 levels by ticlopidine in TNF-α stimulated human umbilical vein endothelial cells

Hu, C. J., Lee, Y. L., Shih, N. Y., Yang, Y. Y., Charoenfuprasert, S., Dai, Y. S., Chang, S. M., Tsai, Y-H., Tseng, H., Liu, C. Y. & Leu, S. J., 2009, In : Journal of Biomedicine and Biotechnology. 2009, 917837.

Research output: Contribution to journalArticle

Ticlopidine
Chemokine CCL2
Endothelial cells
Human Umbilical Vein Endothelial Cells
Interleukin-8
11 Citations (Scopus)

Taiwanese native plants inhibit matrix metalloproteinase-9 activity after ultraviolet B irradiation

Lee, Y. L., Lee, M. H., Chang, H. J., Huang, P. Y., Huang, I. J., Cheng, K. T. & Leu, S. J., Mar 2009, In : Molecules. 14, 3, p. 1062-1071 10 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Vitis
Irradiation
irradiation
matrices
2008
43 Citations (Scopus)

Alterations of serum brain-derived neurotrophic factor levels in early alcohol withdrawal

Huang, M. C., Chen, C. H., Chen, C. H., Liu, S. C., Ho, C. J., Shen, W. W. & Leu, S. J., May 2008, In : Alcohol and Alcoholism. 43, 3, p. 241-245 5 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Alcohols
Serum
Alcoholics
Immunosorbents
16 Citations (Scopus)

Defective functions of circulating CD4+CD25+ and CD4+CD25- T cells in patients with chronic ordinary urticaria

Chen, W. C., Chiang, B. L., Liu, H. E., Leu, S. J. & Lee, Y. L., Aug 2008, In : Journal of Dermatological Science. 51, 2, p. 121-130 10 p.

Research output: Contribution to journalArticle

T-cells
Urticaria
T-Lymphocytes
Regulatory T-Lymphocytes
Blood
23 Citations (Scopus)

Inflammatory mediators of cerebrospinal fluid from patients with spinal cord injury

Tsai, M. C., Wei, C. P., Lee, D. Y., Tseng, Y. T., Tsai, M. D., Shih, Y. L., Lee, Y-H., Chang, S. F. & Leu, S. J., Dec 2008, In : Surgical Neurology. 70, SUPPL. 1

Research output: Contribution to journalArticle

Spinal Cord Injuries
Cerebrospinal Fluid
Therapeutics
Cytokines
Tissue Inhibitor of Metalloproteinase-1
5 Citations (Scopus)

The effect of Chinese herbal medicines on TNF-α induced matrix metalloproteinase-1, -9 activities and interleukin-8 secretion

Lee, M. H., Yang, Y. Y., Tsai, Y-H., Lee, Y. L., Huang, P. Y., Huang, I. J., Cheng, K. T. & Leu, S. J., Oct 2008, In : Botanical Studies. 49, 4, p. 301-309 9 p.

Research output: Contribution to journalArticle

interstitial collagenase
herbal medicines
interleukin-8
skin (animal)
secretion
2007
13 Citations (Scopus)

A dominant antigenic epitope on SARS-CoV spike protein identified by an avian single-chain variable fragment (scFv)-expressing phage

Lee, Y. C., Leu, S. J. C., Hung, H. C., Wu, H. H., Huang, I. J., Hsieh, W. S., Chiu, W. T., Hsieh, M. S., Cheng, T. F. & Yang, Y. Y., May 15 2007, In : Veterinary Immunology and Immunopathology. 117, 1-2, p. 75-85 11 p.

Research output: Contribution to journalArticle

Avian Proteins
Severe Acute Respiratory Syndrome
Single-Chain Antibodies
bacteriophages
Bacteriophages
3 Citations (Scopus)

Characterization of novel transforming growth factor-beta type I receptors found in malignant pleural effusion tumor cells

Chen, K. L., Liu, W. H., Yang, Y. Y., Leu, S. J. C. & Shih, N. Y., Aug 17 2007, In : BMC Molecular Biology. 8, 72.

Research output: Contribution to journalArticle

Malignant Pleural Effusion
Tumors
Protein Sorting Signals
Cells
Neoplasms
8 Citations (Scopus)

Chicken single-chain variable fragments against the SARS-CoV spike protein

Lee, Y. C., Leu, S. J. C., Hu, C. J., Shih, N. Y., Huang, I. J., Wu, H. H., Hsieh, W. S., Chiang, B. L., Chiu, W. T. & Yang, Y. Y., Dec 2007, In : Journal of Virological Methods. 146, 1-2, p. 104-111 8 p.

Research output: Contribution to journalArticle

Severe Acute Respiratory Syndrome
Single-Chain Antibodies
Chickens
Proteins
Bacteriophages
34 Citations (Scopus)
GAP-43 Protein
Janus Kinases
STAT3 Transcription Factor
Spinal Ganglia
Neurites
18 Citations (Scopus)
Macrophages
Granulocyte-Macrophage Colony-Stimulating Factor
Dendritic Cells
Monocytes
Interleukin-4
2006
9 Citations (Scopus)

Anti-heat shock protein 90 is increased in acute mania

Shen, W. W., Liu, H. C., Yang, Y. Y., Lin, C. Y., Chen, K. P., Tsai, T-S. & Leu, S. J., Aug 2006, In : Australian and New Zealand Journal of Psychiatry. 40, 8, p. 712-716 5 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Bipolar Disorder
Autoantibodies
Serum
Chaperonin 60