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Personal profile

Education

  • 2009 PhD, Graduate Institute of Life Sciences, National Defence Medical Center
  • 2002 Master, Department of Life Science, National Tsing-Hua University

Education

  • 2016- Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University.
  • 2017- Jointly Appointed Assistant Professor, Ph.D Program in Biotechnology Research and Development, Taipei Medical University.
  • 2011-2016 Postdoctoral Fellow, BRIC, University of Copenhagen.
  • 2009-2011 Postdoctoral Fellow, Genomics Research Center, Academia Sinica.

Research Interests

  • Chromatin Replication, Genome Stability

Fingerprint Dive into the research topics where Sung-Bau Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Chromatin Medicine & Life Sciences
Chromatin Assembly Factor-1 Medicine & Life Sciences
Histones Medicine & Life Sciences
Cytomegalovirus Medicine & Life Sciences
Methyltransferases Medicine & Life Sciences
Transcriptional Activation Medicine & Life Sciences
DNA Replication Medicine & Life Sciences
Chemical activation Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2017 2020

發展干擾染色質複製時期基因體穩定性之藥劑

Lee, S.

8/1/197/1/20

Project: A - Government Institutionb - Ministry of Science and Technology

TLK於染色質複製之功能及調控 (第二年)

Lee, S.

8/1/187/1/19

Project: A - Government Institutionb - Ministry of Science and Technology

TLK於染色質複製及腫瘤抑制之功能及調控

Lee, S.

8/1/177/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 2009 2019

  • 436 Citations
  • 6 h-Index
  • 9 Article
  • 1 Short survey

Endocytosis-dependent lysosomal degradation of Src induced by protease-activated receptor 1

Tsai, C. C., Kuo, F. T., Lee, S. B., Chang, Y. T. & Fu, H. W., Mar 1 2019, In : FEBS Letters. 593, 5, p. 504-517 14 p.

Research output: Contribution to journalArticle

PAR-1 Receptor
Endocytosis
Degradation
Chemical activation
Dynamins
5 Citations (Scopus)

Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors

Lee, S. B., Segura-Bayona, S., Villamor-Payà, M., Saredi, G., Todd, M. A. M., Attolini, C. S. O., Chang, T. Y., Stracker, T. H. & Groth, A., Aug 8 2018, In : Science advances. 4, 8, eaat4985.

Research output: Contribution to journalArticle

Adenosine
Phosphotransferases
Chromatin Assembly and Disassembly
Nucleosomes
DNA Replication
30 Citations (Scopus)

BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

Feng, Y., Vlassis, A., Roques, C., Lalonde, M. E., González-Aguilera, C., Lambert, J. P., Lee, S. B., Zhao, X., Alabert, C., Johansen, J. V., Paquet, E., Yang, X. J., Gingras, A. C., Côté, J. & Groth, A., Jan 1 2016, In : EMBO Journal. 35, 2, p. 176-192 17 p.

Research output: Contribution to journalArticle

Acetylation
Replication Origin
Histones
Fingers
Chemical activation
147 Citations (Scopus)

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

Alabert, C., Bukowski-Wills, J-C., Lee, S-B., Kustatscher, G., Nakamura, K., de Lima Alves, F., Menard, P., Mejlvang, J., Rappsilber, J. & Groth, A., Feb 23 2014, In : Nature Cell Biology. 16, 3, p. 281-93 13 p.

Research output: Contribution to journalArticle

DNA Replication
Proteomics
Chromatin
Genomic Instability
Proliferating Cell Nuclear Antigen

H3K56me1 Marks a Spot for PCNA

Lee, S. B., Jasencakova, Z. & Groth, A., Apr 13 2012, In : Molecular Cell. 46, 1, p. 1-2 2 p.

Research output: Contribution to journalShort survey

Proliferating Cell Nuclear Antigen
Methyltransferases
Chromatin