Projects per year
Personal profile
Education
- 2009 PhD, Graduate Institute of Life Sciences, National Defence Medical Center
- 2002 Master, Department of Life Science, National Tsing-Hua University
Education
- 2016- Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University.
- 2017- Jointly Appointed Assistant Professor, Ph.D Program in Biotechnology Research and Development, Taipei Medical University.
- 2011-2016 Postdoctoral Fellow, BRIC, University of Copenhagen.
- 2009-2011 Postdoctoral Fellow, Genomics Research Center, Academia Sinica.
Research Interests
- Chromatin Replication, Genome Stability
Fingerprint Dive into the research topics where Sung-Bau Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 5 Similar Profiles
Chromatin
Medicine & Life Sciences
Chromatin Assembly Factor-1
Medicine & Life Sciences
Histones
Medicine & Life Sciences
Cytomegalovirus
Medicine & Life Sciences
Methyltransferases
Medicine & Life Sciences
Transcriptional Activation
Medicine & Life Sciences
DNA Replication
Medicine & Life Sciences
Chemical activation
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2017 2020
發展干擾染色質複製時期基因體穩定性之藥劑
8/1/19 → 7/1/20
Project: A - Government Institution › b - Ministry of Science and Technology
TLK於染色質複製之功能及調控 (第二年)
8/1/18 → 7/1/19
Project: A - Government Institution › b - Ministry of Science and Technology
TLK於染色質複製及腫瘤抑制之功能及調控
8/1/17 → 7/31/18
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output 2009 2019
Endocytosis-dependent lysosomal degradation of Src induced by protease-activated receptor 1
Tsai, C. C., Kuo, F. T., Lee, S. B., Chang, Y. T. & Fu, H. W., Mar 1 2019, In : FEBS Letters. 593, 5, p. 504-517 14 p.Research output: Contribution to journal › Article
PAR-1 Receptor
Endocytosis
Degradation
Chemical activation
Dynamins
5
Citations
(Scopus)
Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors
Lee, S. B., Segura-Bayona, S., Villamor-Payà, M., Saredi, G., Todd, M. A. M., Attolini, C. S. O., Chang, T. Y., Stracker, T. H. & Groth, A., Aug 8 2018, In : Science advances. 4, 8, eaat4985.Research output: Contribution to journal › Article
Adenosine
Phosphotransferases
Chromatin Assembly and Disassembly
Nucleosomes
DNA Replication
34
Citations
(Scopus)
BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation
Feng, Y., Vlassis, A., Roques, C., Lalonde, M. E., González-Aguilera, C., Lambert, J. P., Lee, S. B., Zhao, X., Alabert, C., Johansen, J. V., Paquet, E., Yang, X. J., Gingras, A. C., Côté, J. & Groth, A., Jan 1 2016, In : EMBO Journal. 35, 2, p. 176-192 17 p.Research output: Contribution to journal › Article
Acetylation
Replication Origin
Histones
Fingers
Chemical activation
152
Citations
(Scopus)
Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components
Alabert, C., Bukowski-Wills, J-C., Lee, S-B., Kustatscher, G., Nakamura, K., de Lima Alves, F., Menard, P., Mejlvang, J., Rappsilber, J. & Groth, A., Feb 23 2014, In : Nature Cell Biology. 16, 3, p. 281-93 13 p.Research output: Contribution to journal › Article
DNA Replication
Proteomics
Chromatin
Genomic Instability
Proliferating Cell Nuclear Antigen
H3K56me1 Marks a Spot for PCNA
Lee, S. B., Jasencakova, Z. & Groth, A., Apr 13 2012, In : Molecular Cell. 46, 1, p. 1-2 2 p.Research output: Contribution to journal › Short survey
Proliferating Cell Nuclear Antigen
Methyltransferases
Chromatin