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Personal profile

Education

  • 2009 PhD, Graduate Institute of Life Sciences, National Defence Medical Center
  • 2002 Master, Department of Life Science, National Tsing-Hua University

Experience

  • 2020- Assistant Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
  • 2020- Jointly Appointed Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University
  • 2016-2020 Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University.
  • 2017-2020 Jointly Appointed Assistant Professor, Ph.D Program in Biotechnology Research and Development, Taipei Medical University.
  • 2011-2016 Postdoctoral Fellow, BRIC, University of Copenhagen.
  • 2009-2011 Postdoctoral Fellow, Genomics Research Center, Academia Sinica.

Research Interests

  • Drug discovery, Genomic instability, Chromatin replication

Fingerprint Dive into the research topics where Sung-Bau Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Projects

Discovery of Agents Disturbing Genome Stability during Chromatin Replication

Lee, S.

8/1/197/31/20

Project: A - Government Institutionb - Ministry of Science and Technology

Targeting replication stress in cancer therapy (I)

Lee, S.

7/1/196/30/20

Project: B - Project of TMUi - Other (Funded by TMU)

Targeting replication stress in cancer therapy(II)

Lee, S.

7/1/206/30/21

Project: B - Project of TMUi - Other (Funded by TMU)

Tlk Function and Regulation in Chromatin Replication (2nd Years)

Lee, S.

8/1/187/1/19

Project: A - Government Institutionb - Ministry of Science and Technology

Tlk Function and Regulation in Chromatin Replication

Lee, S.

8/1/177/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output

  • 483 Citations
  • 7 h-Index
  • 10 Article
  • 1 Short survey
  • Endocytosis-dependent lysosomal degradation of Src induced by protease-activated receptor 1

    Tsai, C. C., Kuo, F. T., Lee, S. B., Chang, Y. T. & Fu, H. W., Mar 1 2019, In : FEBS Letters. 593, 5, p. 504-517 14 p.

    Research output: Contribution to journalArticle

  • Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors

    Lee, S. B., Segura-Bayona, S., Villamor-Payà, M., Saredi, G., Todd, M. A. M., Attolini, C. S. O., Chang, T. Y., Stracker, T. H. & Groth, A., Aug 8 2018, In : Science advances. 4, 8, eaat4985.

    Research output: Contribution to journalArticle

  • 7 Citations (Scopus)

    BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

    Feng, Y., Vlassis, A., Roques, C., Lalonde, M. E., González-Aguilera, C., Lambert, J. P., Lee, S. B., Zhao, X., Alabert, C., Johansen, J. V., Paquet, E., Yang, X. J., Gingras, A. C., Côté, J. & Groth, A., Jan 1 2016, In : EMBO Journal. 35, 2, p. 176-192 17 p.

    Research output: Contribution to journalArticle

  • 40 Citations (Scopus)

    Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

    Alabert, C., Bukowski-Wills, J-C., Lee, S-B., Kustatscher, G., Nakamura, K., de Lima Alves, F., Menard, P., Mejlvang, J., Rappsilber, J. & Groth, A., Feb 23 2014, In : Nature Cell Biology. 16, 3, p. 281-93 13 p.

    Research output: Contribution to journalArticle

  • 161 Citations (Scopus)