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Personal profile


  • 2009 PhD, Graduate Institute of Life Sciences, National Defence Medical Center
  • 2002 Master, Department of Life Science, National Tsing-Hua University


  • 2016- Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University.
  • 2017- Jointly Appointed Assistant Professor, Ph.D Program in Biotechnology Research and Development, Taipei Medical University.
  • 2011-2016 Postdoctoral Fellow, BRIC, University of Copenhagen.
  • 2009-2011 Postdoctoral Fellow, Genomics Research Center, Academia Sinica.

Research Interests

  • Chromatin Replication, Genome Stability

Fingerprint Dive into the research topics where Sung-Bau Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Chromatin Medicine & Life Sciences
Chromatin Assembly Factor-1 Medicine & Life Sciences
Histones Medicine & Life Sciences
Cytomegalovirus Medicine & Life Sciences
Methyltransferases Medicine & Life Sciences
Transcriptional Activation Medicine & Life Sciences
DNA Replication Medicine & Life Sciences
Chemical activation Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2017 2020


Lee, S.


Project: A - Government Institutionb - Ministry of Science and Technology

TLK於染色質複製之功能及調控 (第二年)

Lee, S.


Project: A - Government Institutionb - Ministry of Science and Technology


Lee, S.


Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 2009 2019

  • 454 Citations
  • 6 h-Index
  • 9 Article
  • 1 Short survey

Endocytosis-dependent lysosomal degradation of Src induced by protease-activated receptor 1

Tsai, C. C., Kuo, F. T., Lee, S. B., Chang, Y. T. & Fu, H. W., Mar 1 2019, In : FEBS Letters. 593, 5, p. 504-517 14 p.

Research output: Contribution to journalArticle

PAR-1 Receptor
Chemical activation
5 Citations (Scopus)

Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors

Lee, S. B., Segura-Bayona, S., Villamor-Payà, M., Saredi, G., Todd, M. A. M., Attolini, C. S. O., Chang, T. Y., Stracker, T. H. & Groth, A., Aug 8 2018, In : Science advances. 4, 8, eaat4985.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
DNA Replication
34 Citations (Scopus)

BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

Feng, Y., Vlassis, A., Roques, C., Lalonde, M. E., González-Aguilera, C., Lambert, J. P., Lee, S. B., Zhao, X., Alabert, C., Johansen, J. V., Paquet, E., Yang, X. J., Gingras, A. C., Côté, J. & Groth, A., Jan 1 2016, In : EMBO Journal. 35, 2, p. 176-192 17 p.

Research output: Contribution to journalArticle

Replication Origin
Chemical activation
152 Citations (Scopus)

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

Alabert, C., Bukowski-Wills, J-C., Lee, S-B., Kustatscher, G., Nakamura, K., de Lima Alves, F., Menard, P., Mejlvang, J., Rappsilber, J. & Groth, A., Feb 23 2014, In : Nature Cell Biology. 16, 3, p. 281-93 13 p.

Research output: Contribution to journalArticle

DNA Replication
Genomic Instability
Proliferating Cell Nuclear Antigen

H3K56me1 Marks a Spot for PCNA

Lee, S. B., Jasencakova, Z. & Groth, A., Apr 13 2012, In : Molecular Cell. 46, 1, p. 1-2 2 p.

Research output: Contribution to journalShort survey

Proliferating Cell Nuclear Antigen