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Research Output 1991 2019

  • 2309 Citations
  • 28 h-Index
  • 110 Article
  • 2 Meeting Abstract
  • 1 Letter
  • 1 Review article
2019

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide

Lee, C. C., Chang, W. H., Chang, Y. S., Yang, J. M., Chang, C. S., Hsu, K. C., Chen, Y. T., Liu, T. Y., Chen, Y. C., Lin, S. Y., Wu, Y. C. & Chang, J. G., Jan 1 2019, In : Molecular Oncology.

Research output: Contribution to journalArticle

Open Access
Pyrazines
Amiloride
Alternative Splicing
Neoplasms
RNA Sequence Analysis

Deep Intronic Variant c.5999-277G>A of F8 Gene May Be a Hot-Spot Mutation for Mild Hemophilia A Patients Without Mutation in Exonic DNA

Chang, C-Y., Perng, C-L., Cheng, S-N., Hu, S-H., Wu, T-Y., Lin, S-Y. & Chen, Y-C., May 7 2019, In : European Journal of Haematology.

Research output: Contribution to journalArticle

Hemophilia A
Mutation
DNA
Exons
Genes

Simply Mixing Poly Protein G with Detection Antibodies Enhances the Detection Limit and Sensitivity of Immunoassays

Chen, Y. J., Chen, M., Cheng, T. L., Roffler, S. R., Lin, S. Y., Hsu, H. L., Wang, C. H., Chen, C. Y., Kao, A. P., Cheng, J. J. & Chuang, K. H., Jan 1 2019, In : Analytical Chemistry.

Research output: Contribution to journalArticle

Antibodies
Proteins
Flow cytometry
Molecules
Interferons
2018
Dioscorea
Glucose Intolerance
dipeptides
Dipeptides
yams
4 Citations (Scopus)
docetaxel
Bispecific Antibodies
Lecithins
Drug Delivery Systems
Neoplasms
1 Citation (Scopus)

MCPIP3 as a potential metastasis suppressor gene in human colorectal cancer

Suk, F. M., Chang, C. C., Lin, R. J., Lin, S. Y., Chen, Y. T. & Liang, Y. C., May 3 2018, In : International Journal of Molecular Sciences. 19, 5, 1350.

Research output: Contribution to journalArticle

Monocyte Chemoattractant Proteins
monocytes
suppressors
metastasis
Tumor Suppressor Genes
2 Citations (Scopus)

Surface assembly of poly(I:C) on polyethyleneimine-modified gelatin nanoparticles as immunostimulatory carriers for mucosal antigen delivery

Lin, S. F., Jiang, P. L., Tsai, J. S., Huang, Y. Y., Lin, S. Y., Lin, J. H. & Liu, D. Z., Jan 1 2018, (Accepted/In press) In : Journal of Biomedical Materials Research - Part B Applied Biomaterials.

Research output: Contribution to journalArticle

Polyethyleneimine
Poly I-C
Gelatin
Antigens
Ovalbumin
2 Citations (Scopus)

ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner

Suk, F-M., Chang, C-C., Lin, R-J., Lin, S-Y., Liu, S-C., Jau, C-F. & Liang, Y-C., Feb 9 2018, In : Scientific Reports. 8, 1, p. 2742

Research output: Contribution to journalArticle

Cyclin D
Cell Proliferation
Zinc Fingers
HCT116 Cells
Cyclin B
2017
2 Citations (Scopus)

Hot-Water Extracts from Roots of Vitis thunbergii var. taiwaniana and Identified ε-Viniferin Improve Obesity in High-Fat Diet-Induced Mice

Lu, Y. L., Lin, S. Y., Fang, S. U., Hsieh, Y. Y., Chen, C. R., Wen, C. L., Chang, C. I. & Hou, W. C., Mar 29 2017, In : Journal of Agricultural and Food Chemistry. 65, 12, p. 2521-2529 9 p.

Research output: Contribution to journalArticle

viniferins
Vitis
High Fat Diet
high fat diet
Nutrition
4 Citations (Scopus)

Modulation the alternative splicing of GLA (IVS4+919G>A) in Fabry disease

Chang, W. H., Niu, D. M., Lu, C. Y., Lin, S. Y., Liu, T. C. & Chang, J. G., Apr 1 2017, In : PLoS One. 12, 4, e0175929.

Research output: Contribution to journalArticle

Fabry Disease
Amiloride
alternative splicing
Alternative Splicing
Histone Code
5 Citations (Scopus)

Prevalence and severity by age and other clinical correlates of haemophilic arthropathy of the elbow, knee and ankle among Taiwanese patients with haemophilia

Chang, C. Y., Li, T. Y., Cheng, S. N., Pan, R. Y., Wang, H-J., Lin, S. Y. & Chen, Y. C., Mar 1 2017, In : Haemophilia. 23, 2, p. 284-291 8 p.

Research output: Contribution to journalArticle

Joint Diseases
Hemophilia A
Elbow
Ankle
Knee
1 Citation (Scopus)

Primary Sjogren's syndrome and the risk of acute pancreatitis: A nationwide cohort study

Chang, C. C., Chang, Y. S., Wang, S. H., Lin, S. Y., Chen, Y. H. & Chen, J. H., Aug 1 2017, In : BMJ Open. 7, 8, e014807.

Research output: Contribution to journalArticle

Sjogren's Syndrome
Pancreatitis
Cohort Studies
Taiwan
Population
2016
5 Citations (Scopus)

Protective Effects of Minor Components of Curcuminoids on Hydrogen Peroxide-Treated Human HaCaT Keratinocytes

Liu, Y. H., Lin, Y. S., Huang, Y. W., Fang, S. U., Lin, S. Y. & Hou, W. C., May 11 2016, In : Journal of Agricultural and Food Chemistry. 64, 18, p. 3598-3608 11 p.

Research output: Contribution to journalArticle

keratinocytes
Keratinocytes
Hydrogen Peroxide
protective effect
hydrogen peroxide
1 Citation (Scopus)

Successful multivessel percutaneous coronary intervention for acute coronary syndrome in a HIV-positive severe haemophiliac

Chang, C. Y., Lin, S. Y., Tsai, J. R., Tsai, C. H. & Chen, Y. C., Sep 1 2016, In : Haemophilia. 22, 5, p. e481-e484

Research output: Contribution to journalLetter

Percutaneous Coronary Intervention
Acute Coronary Syndrome
HIV
5 Citations (Scopus)
Dioscorea
Dipeptidyl Peptidase 4
yams
glucose tolerance
Glucose Tolerance Test
2015
7 Citations (Scopus)

Bortezomib inhibits Burkitt's lymphoma cell proliferation by downregulating sumoylated hnRNP K and c-Myc expression

Suk, F. M., Lin, S. Y., Lin, R-J., Hsine, Y. H., Liao, Y. J., Fang, S. U. & Liang, Y. C., 2015, In : Oncotarget. 6, 28, p. 25988-26001 14 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein K
Burkitt Lymphoma
Down-Regulation
Cell Proliferation
Molecular Weight
11 Citations (Scopus)
Macrophage Colony-Stimulating Factor
Extracellular Signal-Regulated MAP Kinases
Cytoplasmic and Nuclear Receptors
Osteogenesis
RANK Ligand

CanMEDS角色與醫學生臨床情境認知之相容性探究

Translated title of the contribution: CanMEDS roles as framework for analyzing Taiwanese medical students’ reflective journals: an exploratory research for cross-cultural compatibility唐功培, 康以諾, 何建志, 曾櫻枝, 林宗達, 林時宜 & 陳建宇, 2015, In : 中榮醫教. 18, p. 21-28 8 p.

Research output: Contribution to journalArticle

role expectation
medical student
scenario
communicator
incompatibility

Correction: Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array

Chang, C. C., Chen, L. Y., Yang, K. H., Chen, Q. Y., Liang, Y. C., Lin, S. Y. & Liu, Y. C., Aug 12 2015, In : RSC Advances. 5, 86, p. 70501 1 p.

Research output: Contribution to journalArticle

Silver
Raman scattering
Masks
Nanoparticles
14 Citations (Scopus)

Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface

Cheng, T. C., Tu, S. H., Chen, L. C., Chen, M. Y., Chen, W. Y., Lin, Y-K., Ho, C. T., Lin, S. Y., Wu, C. H. & Ho, Y. S., 2015, In : Oncotarget. 6, 25, p. 21283-21300 18 p.

Research output: Contribution to journalArticle

alpha-L-Fucosidase
Triple Negative Breast Neoplasms
Glycosylation
Down-Regulation
Survival
6 Citations (Scopus)
Ganoderma lucidum
solid state fermentation
feed additives
prebiotics
broiler chickens
7 Citations (Scopus)

Effects of yam dioscorin interventions on improvements of the metabolic syndrome in high-fat diet-induced obese rats

Shih, S-L., Lin, Y-S., Lin, S-Y. & Hou, W-C., 2015, In : Botanical Studies. 56, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Glycine hydroxamate inhibits tyrosinase activity and melanin contents through downregulating cAMP/PKA signaling pathways

Lin, Y. S., Wu, W. C., Lin, S. Y. & Hou, W. C., 2015, In : Amino Acids. 47, 3, p. 617-625 9 p.

Research output: Contribution to journalArticle

Monophenol Monooxygenase
Melanins
Glycine
Down-Regulation
Agaricales
20 Citations (Scopus)

High anti-dengue virus activity of the OAS gene family is associated with increased severity of dengue

Simon-Loriere, E., Lin, R-J., Kalayanarooj, S. M., Chuansumrit, A., Casademont, I., Lin, S. Y., Yu, H. P., Lert-Itthiporn, W., Chaiyaratana, W., Tangthawornchaikul, N., Tangnararatchakit, K., Vasanawathana, S., Chang, B. L., Suriyaphol, P., Yoksan, S., Malasit, P., Despres, P., Paul, R., Lin, Y. L. & Sakuntabhai, A., 2015, In : Journal of Infectious Diseases. 212, 12, p. 2011-2020 10 p.

Research output: Contribution to journalArticle

Dengue Virus
Dengue
Genes
Virus Diseases
Antiviral Agents
17 Citations (Scopus)
Critical Care
Methicillin-Resistant Staphylococcus aureus
Intensive Care Units
Costs and Cost Analysis
Mortality
9 Citations (Scopus)

Increased risk of hepatocellular carcinoma in chronic hepatitis C patients with new onset diabetes: A nation-wide cohort study

Huang, Y. W., Wang, T. C., Yang, S. S., Lin, S. Y., Fu, S. C., Hu, J. T., Liu, C. J., Kao, J. H. & Chen, D. S., Oct 1 2015, In : Alimentary Pharmacology and Therapeutics. 42, 7, p. 902-911 10 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Hepatocellular Carcinoma
Cohort Studies
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Mortality
7 Citations (Scopus)

N-hydroxycinnamide derivatives of osthole ameliorate hyperglycemia through activation of AMPK and p38 MAPK

Lee, W. H., Wu, H. H., Huang, W. J., Li, Y. N., Lin, R-J., Lin, S. Y. & Liang, Y. C., Mar 1 2015, In : Molecules. 20, 3, p. 4516-4529 14 p.

Research output: Contribution to journalArticle

hyperglycemia
AMP-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
glucose
Hyperglycemia
2 Citations (Scopus)

Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array

Chang, C. C., Chen, L. Y., Yang, K. H., Chen, Q. Y., Liang, Y. C., Lin, S. Y. & Liu, Y. C., Jul 23 2015, In : RSC Advances. 5, 81, p. 66096-66103 8 p.

Research output: Contribution to journalArticle

Silver
Raman scattering
Masks
Nanoparticles
Calcium
3 Citations (Scopus)

Vitis thunbergii var. taiwaniana Extracts and Purified Compounds Ameliorate Obesity in High-Fat Diet-Induced Obese Mice

Lin, S. Y., Huang, G. C., Hsieh, Y. Y., Lin, Y. S., Han, C. H., Wen, C. L., Chang, C. I. & Hou, W. C., Oct 28 2015, In : Journal of Agricultural and Food Chemistry. 63, 42, p. 9286-9294 9 p.

Research output: Contribution to journalArticle

Obese Mice
Vitis
High Fat Diet
high fat diet
Nutrition
2014
19 Citations (Scopus)
Dioscorea
dipeptides
Dipeptides
yams
Computer Simulation
19 Citations (Scopus)
Dioscorea
yams
Galactose
galactose
tubers
27 Citations (Scopus)

MCPIP1 suppresses hepatitis C virus replication and negatively regulates virus-induced proinflammatory cytokine responses

Lin, R-J., Chu, J. S., Chien, H. L., Tseng, C. H., Ko, P. C., Mei, Y. Y., Tang, W. C., Kao, Y. T., Cheng, H. Y., Liang, Y. C. & Lin, S. Y., Oct 15 2014, In : Journal of Immunology. 193, 8, p. 4159-4168 10 p.

Research output: Contribution to journalArticle

Virus Replication
Hepacivirus
Cytokines
Viruses
Virus Diseases
11 Citations (Scopus)
Cell Movement
Transforming Growth Factors
Adenocarcinoma
Derivatives
Phosphorylation
6 Citations (Scopus)

Trends in the epidemiology, diagnosed age and mortality rate of haemophiliacs in Taiwan: A population-based study, 1997-2009

Chang, C. Y., Yeh, G-C., Lin, S-Y., Tseng, I. J., Tsai, C. H. & Lee, Y-W., 2014, In : Haemophilia. 20, 4, p. 535-540 6 p.

Research output: Contribution to journalArticle

Taiwan
Epidemiology
Hemophilia A
Mortality
Population
2013
17 Citations (Scopus)

15,16-dihydrotanshinone i-induced apoptosis in human colorectal cancer cells: Involvement of ATF3

Suk, F. M., Jou, W. J., Lin, R-J., Lin, S. Y., Tzeng, F. Y. & Liang, Y. C., Aug 2013, In : Anticancer Research. 33, 8, p. 3225-3232 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Apoptosis
Activating Transcription Factor 3
Salvia miltiorrhiza
Medicinal Plants
7 Citations (Scopus)

Characteristics of patients with Clostridium difficile infection in Taiwan

Lin, Y. C., Huang, Y. T., Lee, T. F., Lee, N. Y., Liao, C. H., Lin, S. Y., Ko, W. C. & Hsueh, P. R., Oct 2013, In : Epidemiology and Infection. 141, 10, p. 2031-2038 8 p.

Research output: Contribution to journalArticle

Clostridium Infections
Clostridium difficile
Taiwan
Genes
Mortality
10 Citations (Scopus)

Cytotoxicity of (-)-vitisin B in human leukemia cells

Wu, S. S., Chen, L. G., Lin, R-J., Lin, S. Y., Lo, Y. E. & Liang, Y. C., Jul 2013, In : Drug and Chemical Toxicology. 36, 3, p. 313-319 7 p.

Research output: Contribution to journalArticle

Resveratrol
Cell death
Cytotoxicity
Leukemia
Cell proliferation
59 Citations (Scopus)

MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation

Lin, R-J., Chien, H. L., Lin, S. Y., Chang, B. L., Yu, H. P., Tang, W. C. & Lin, Y. L., Mar 2013, In : Nucleic Acids Research. 41, 5, p. 3314-3326 13 p.

Research output: Contribution to journalArticle

Chemokine CCL2
RNA Stability
Viral RNA
Ribonucleases
Antiviral Agents
9 Citations (Scopus)
Cytotoxicity
Colon
Adenocarcinoma
Derivatives
Phosphorylation
20 Citations (Scopus)

Postoperative adverse outcomes after non-hepatic surgery in patients with liver cirrhosis

Lin, C-S., Lin, S-Y., Chang, C-C., Wang, H. H., Liao, C-C. & Chen, T-L., Dec 2013, In : British Journal of Surgery. 100, 13, p. 1784-1790 7 p.

Research output: Contribution to journalArticle

Liver Cirrhosis
Odds Ratio
Mortality
Fibrosis
Confidence Intervals
2012
19 Citations (Scopus)

Effects of nicotinic acid derivatives on tyrosinase inhibitory and antioxidant activities

Lin, Y. S., Chen, S-H., Huang, W. J., Chen, C. H., Chien, M. Y., Lin, S. Y. & Hou, W. C., Jun 15 2012, In : Food Chemistry. 132, 4, p. 2074-2080 7 p.

Research output: Contribution to journalArticle

Monophenol Monooxygenase
Niacin
niacin
catechol oxidase
Antioxidants
10 Citations (Scopus)

Esomeprazole alone compared with esomeprazole plus aspirin for the treatment of aspirin-related peptic ulcers

Liu, C. P., Chen, W. C., Lai, K. H., Mar, G. Y., Lin, S. Y., Ger, L. P. & Hsu, P. I., Jul 2012, In : American Journal of Gastroenterology. 107, 7, p. 1022-1029 8 p.

Research output: Contribution to journalArticle

Esomeprazole
Peptic Ulcer
Aspirin
Ulcer
Confidence Intervals
28 Citations (Scopus)

Folic acid inhibits endothelial cell proliferation through activating the cSrc/ERK 2/NF-jB/p53 pathway mediated by folic acid receptor

Lin, S. Y., Lee, W. R., Su, Y. F., Hsu, S. P., Lin, H. C., Ho, P. Y., Hou, T. C., Chou, Y. P., Kuo, C. T. & Lee, W. S., 2012, In : Angiogenesis. 15, 4, p. 671-683 13 p.

Research output: Contribution to journalArticle

Endothelial cells
Cell proliferation
Folic Acid
Endothelial Cells
Cell Proliferation
1 Citation (Scopus)

The antinociceptive and anti-inflammatory activities of Petasites formosanus Kitamura extract

Lin, S. Y., Teng, H. L., Tseng, S. H., Chen, L. G. & Wang, C. C., Oct 2012, In : Botanical Studies. 53, 4, p. 431-438 8 p.

Research output: Contribution to journalArticle

Petasites
anti-inflammatory activity
leaf extracts
carrageenan
edema
2011
20 Citations (Scopus)
Salvia miltiorrhiza
Prostate
Apoptosis
Carcinoma
Transcription Factor CHOP
37 Citations (Scopus)

Antimicrobial susceptibilities and molecular epidemiology of clinical isolates of Clostridium difficile in Taiwan

Lin, Y. C., Huang, Y. T., Tsai, P. J., Lee, T. F., Lee, N. Y., Liao, C. H., Lin, S. Y., Ko, W. C. & Hsueh, P. R., Apr 2011, In : Antimicrobial Agents and Chemotherapy. 55, 4, p. 1701-1705 5 p.

Research output: Contribution to journalArticle

Molecular Epidemiology
Clostridium difficile
Taiwan
Ribotyping
Polymerase Chain Reaction
5 Citations (Scopus)
Colorectal Neoplasms
Epidemiology
Smoking
Microsatellite Instability
Neoplasms

Concurrence of classic type Ehlers-Danlos syndrome and moderate hemophilia A in a Taiwanese: a case report

Chang, C-Y., Tsai, C-H., Tsai, J-R., Yeh, G-C., Lin, S-Y. & Tseng, I. J., Jul 31 2011, In : Journal of Thrombosis and Haemostasis. 9, s2, p. 475 1 p., P-TU-530.

Research output: Contribution to journalMeeting Abstract

45 Citations (Scopus)

Concurrence of type II von Willebrand disease and severe hemophilia B in a Taiwanese: a case report and review of literature

Chang, C-Y., Tsai, C. H., Tsai, J. R., Yeh, G-C., Lin, S-Y. & Tseng, I. J., Jul 31 2011, In : Journal of Thrombosis and Haemostasis. 9, s2, p. 450 1 p., P-TU-452.

Research output: Contribution to journalMeeting Abstract

34 Citations (Scopus)

Osthole enhances glucose uptake through activation of AMP-activated protein kinase in skeletal muscle cells

Lee, W. H., Lin, R-J., Lin, S. Y., Chen, Y. C., Lin, H. M. & Liang, Y. C., Dec 28 2011, In : Journal of Agricultural and Food Chemistry. 59, 24, p. 12874-12881 8 p.

Research output: Contribution to journalArticle

AMP-activated protein kinase
AMP-Activated Protein Kinases
myocytes
Muscle Cells
Muscle