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Research Output 1989 2018

  • 1858 Citations
  • 23 h-Index
  • 79 Article
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Article
2018
5 Citations (Scopus)

AMPK-dependent and independent actions of P2X7 in regulation of mitochondrial and lysosomal functions in microglia

Sekar, P., Huang, D. Y., Hsieh, S. L., Chang, S. F. & Lin, W. W., Nov 20 2018, In : Cell Communication and Signaling. 16, 1, 83.

Research output: Contribution to journalArticle

Mitochondrial Degradation
AMP-Activated Protein Kinases
Microglia
Mitochondrial Dynamics
Chemical activation
3 Citations (Scopus)

Coordinate effects of P2X7 and extracellular acidification in microglial cells

Sekar, P., Huang, D. Y., Chang, S. F. & Lin, W. W., Jan 1 2018, In : Oncotarget. 9, 16, p. 12718-12731 14 p.

Research output: Contribution to journalArticle

Adenosine Triphosphate
Reactive Oxygen Species
Nigericin
Mitochondrial Dynamics
Inflammation
2 Citations (Scopus)

In vitro and in vivo assessment of delivery of hydrophobic molecules and plasmid DNAs with PEO-PPO-PEO polymeric micelles on cornea

Hsiao, F., Huang, P. Y., Aoyagi, T., Chang, S. F. & Liaw, J., Apr 2018, In : Journal of Food and Drug Analysis. 26, 2, p. 869-878

Research output: Contribution to journalArticle

rhodamine B
Energy Transfer
Micelles
cornea
micelles
4 Citations (Scopus)

The Mycobacterial Adjuvant Analogue TDB Attenuates Neuroinflammation via Mincle-Independent PLC-γ1/PKC/ERK Signaling and Microglial Polarization

Mohanraj, M., Sekar, P., Liou, H-H., Chang, S-F. & Lin, W-W., Jun 6 2018, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Kinase
Microglia
Cord Factors
AMP-Activated Protein Kinases
trehalose 6,6'-dibehenate
2016
5 Citations (Scopus)

Electronegative LDL is linked to high-fat, high-cholesterol diet-induced nonalcoholic steatohepatitis in hamsters

Lai, Y. S., Yang, T. C., Chang, P. Y., Chang, S. F., Ho, S. L., Chen, H. L. & Lu, S. C., Apr 1 2016, In : Journal of Nutritional Biochemistry. 30, p. 44-52 9 p.

Research output: Contribution to journalArticle

High Fat Diet
Nutrition
Cricetinae
Fats
Cholesterol
2 Citations (Scopus)

SB203580 increases G-CSF production via a stem-loop destabilizing element in the 3' untranslated region in macrophages independently of its effect on p38 MAPK activity

Chang, S. F., Li, H. C., Huang, Y. P., Tasi, W. J., Chou, Y. Y. & Lu, S. C., Jan 16 2016, In : Journal of Biomedical Science. 23, 1

Research output: Contribution to journalArticle

Macrophages
3' Untranslated Regions
p38 Mitogen-Activated Protein Kinases
Granulocyte Colony-Stimulating Factor
Messenger RNA
3 Citations (Scopus)

YC-1 induces lipid droplet formation in RAW 264.7 macrophages

Tsui, L., Chang, S. F., Huang, H. P., Fong, T. H. & Wang, I. J., Jan 15 2016, (Accepted/In press) In : Journal of Biomedical Science.

Research output: Contribution to journalArticle

Macrophages
Lipids
Foam Cells
Foams
Guanylate Cyclase
2015
3 Citations (Scopus)

Anti-apoptotic gene delivery with cyclo-(D-Trp-Tyr) peptide nanotube via eye drop following corneal epithelial debridement

Lee, Y. H., Chang, S. F. & Liaw, J., Jul 17 2015, In : Pharmaceutics. 7, 3, p. 122-136 15 p.

Research output: Contribution to journalArticle

tryptophyltyrosine
Peptide Nanotubes
Ophthalmic Solutions
Debridement
Genes

Clinical performance of multiplex high-risk e6 mrna expression in comparison with hpv dna subtypes for the identification of women at risk of cervical cancer

Ho, C. M., Pan, K. Y., Chen, Y. Y., Huang, C. Y., Chen, Y. L. & Chang, S. F., Aug 1 2015, In : Journal of Medical Virology. 87, 8, p. 1404-1412 9 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
RNA
DNA
Odds Ratio
Confidence Intervals
3 Citations (Scopus)

Demethylation of HIN-1 reverses paclitaxel-resistance of ovarian clear cell carcinoma through the AKT-mTOR signaling pathway

Ho, C. M., Huang, C. J., Huang, S. H., Chang, S. F. & Cheng, W. F., Oct 24 2015, In : BMC Cancer. 15, 1, 789.

Research output: Contribution to journalArticle

Paclitaxel
Carcinoma
Methylation
Cell Line
decitabine
4 Citations (Scopus)

Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis

Ho, C. M., Shih, T-B., Hsiao, C. C., Huang, S. H., Chang, S-F. & Cheng, W. F., Nov 23 2015, In : Journal of Translational Medicine. 13, 1, 367.

Research output: Contribution to journalArticle

Methylation
Stromal Cells
Tumors
Carcinogenesis
Stem Cells
7 Citations (Scopus)

LPS-induced G-CSF expression in macrophages is mediated by ERK2, but not ERK1

Chang, S. F., Lin, S. S., Yang, H. C., Chou, Y. Y., Gao, J. I. & Lu, S. C., Jun 26 2015, In : PLoS One. 10, 6, e0129685.

Research output: Contribution to journalArticle

granulocyte colony-stimulating factor
Macrophages
Granulocyte Colony-Stimulating Factor
lipopolysaccharides
Lipopolysaccharides
2014
5 Citations (Scopus)
Cefazolin
Agglutination
Polysaccharides
Erythrocytes
Escherichia coli
2 Citations (Scopus)

Gene expression and behavior analysis of PC12 cells grown on synthetic biodegradable fibrous membranes coated with natural biopolymers

Tsai, T. H., Tai, C. C., Wu, Y. H. S., Hung, S. H., Chang, S. F., Yang, C. P. & Tseng, H., 2014, In : Current Nanoscience. 10, 2, p. 235-242 8 p.

Research output: Contribution to journalArticle

Fibrous membranes
Biopolymers
PC12 Cells
Gene expression
Cells
19 Citations (Scopus)

Malondialdehyde mediates oxidized LDL-induced coronary toxicity through the Akt-FGF2 pathway via DNA methylation

Yang, T. C., Chen, Y. J., Chang, S. F., Chen, C. H., Chang, P. Y. & Lu, S. C., Feb 3 2014, In : Journal of Biomedical Science. 21, 1, 11.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
DNA Methylation
Malondialdehyde
Toxicity
Endothelial cells
48 Citations (Scopus)

The effect of type II collagen on MSC osteogenic differentiation and bone defect repair

Chiu, L. H., Lai, W. F. T., Chang, S. F., Wong, C. C., Fan, C. Y., Fang, C. L. & Tsai, Y-H., Mar 2014, In : Biomaterials. 35, 9, p. 2680-2691 12 p.

Research output: Contribution to journalArticle

Collagen Type II
Collagen
Bone
Repair
Bone and Bones
2013
33 Citations (Scopus)

Aspirin protects human coronary artery endothelial cells against atherogenic electronegative LDL via an epigenetic mechanism: A novel cytoprotective role of aspirin in acute myocardial infarction

Chang, P. Y., Chen, Y. J., Chang, F. H., Lu, J., Huang, W. H., Yang, T. C., Lee, Y. T., Chang, S. F., Lu, S. C. & Chen, C. H., Jul 1 2013, In : Cardiovascular Research. 99, 1, p. 137-145 9 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Epigenomics
Aspirin
Coronary Vessels
Endothelial Cells

Biotransformation of dihydroisosteviol and the effects of transformed products on steroidogenic gene expressions

Chang, S. F., Yang, L. M., Huang, T. J., Chen, C. Y., Sheu, S. Y., Liu, P. C. & Lin, S. J., Nov 2013, In : Phytochemistry. 95, p. 268-276 9 p.

Research output: Contribution to journalArticle

Biotransformation
biotransformation
Gene expression
Steroidogenic Factor 1
Gene Expression
5 Citations (Scopus)

Extracellular signal-regulated kinase 2 mediates the expression of granulocyte colony-stimulating factor in invasive cancer cells

Lee, C. H., Lin, S. H., Chang, S. F., Chang, P. Y., Yang, Z. P. & Lu, S. C., Jul 2013, In : Oncology Reports. 30, 1, p. 419-424 6 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 1
Granulocyte Colony-Stimulating Factor
Neoplasms
Tumor Necrosis Factor-alpha
Blood Circulation
2012
Congenital Adrenal Hyperplasia
Genome
Genes
Mutation
Androgens
35 Citations (Scopus)

Isolation and characterization of stromal progenitor cells from ascites of patients with epithelial ovarian adenocarcinoma

Ho, C. M., Chang, S-F., Hsiao, C. C., Chien, T. Y. & Shih, T-B., 2012, In : Journal of Biomedical Science. 19, 1, 23.

Research output: Contribution to journalArticle

Stromal Cells
Ascites
Adenocarcinoma
Stem Cells
Cells
8 Citations (Scopus)

Nanopolymeric micelle effect on the transdermal permeability, the bioavailability and gene expression of plasmid

Tong, Y. C., Yu, T. Y., Chang, S. F. & Liaw, J., Jan 1 2012, In : Molecular Pharmaceutics. 9, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

Micelles
Biological Availability
Permeability
Plasmids
Gene Expression
15 Citations (Scopus)

Oral gene delivery with cyclo -(d -Trp-Tyr) peptide nanotubes

Hsieh, W. H., Chang, S. F., Chen, H. M., Chen, J. H. & Liaw, J., May 7 2012, In : Molecular Pharmaceutics. 9, 5, p. 1231-1249 19 p.

Research output: Contribution to journalArticle

tryptophyltyrosine
Peptide Nanotubes
DNA
Genes
Deoxyribonuclease I
6 Citations (Scopus)

Oxygenated compounds from the bioconversion of isostevic acid and their inhibition of TNF-α and COX-2 expressions in LPS-stimulated RAW 264.7 cells

Yang, L. M., Chang, S. F., Lin, W. K., Chou, B. H., Wang, L. H., Liu, P. C. & Lin, S. J., Mar 2012, In : Phytochemistry. 75, p. 90-98 9 p.

Research output: Contribution to journalArticle

Bioconversion
prostaglandin synthase
dexamethasone
biotransformation
metabolites
19 Citations (Scopus)

Promoter Methylation status of HIN-1 associated with outcomes of ovarian clear cell adenocarcinoma

Ho, C. M., Huang, C. J., Huang, C. Y., Wu, Y. Y., Chang, S. F. & Cheng, W. F., Aug 8 2012, (Accepted/In press) In : Molecular Cancer. p. 53 1 p.

Research output: Contribution to journalArticle

Clear Cell Adenocarcinoma
Methylation
Genes
Multiplex Polymerase Chain Reaction
Paclitaxel
2011
4 Citations (Scopus)

Analysis of the CYP21A2 gene with intergenic recombination and multiple gene deletions in the RCCX module

Chang, S. F. & Lee, H. H., Jan 1 2011, In : Genetic Testing and Molecular Biomarkers. 15, 1-2, p. 35-42 8 p.

Research output: Contribution to journalArticle

Gene Deletion
Genetic Recombination
Southern Blotting
Mutation
Genes
21 Citations (Scopus)

Arctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes

Tsai, W. J., Chang, C. T., Wang, G. J., Li, Z-H., Chang, S. F., Lu, S. C. & Kuo, Y. C., Mar 25 2011, In : Chinese Medicine. 6, 12.

Research output: Contribution to journalArticle

Arctium
Interferons
Interleukin-2
T-Lymphocytes
Gene Expression
3 Citations (Scopus)

Clinical significance of signal pattern of high-risk human papillomavirus using a novel fluorescence in situ hybridization assay in cervical cytology

Ho, C. M., Lee, B. H., Chang, S. F., Chien, T. Y., Huang, S. H., Yan, C. C. & Cheng, W. F., Mar 2011, In : Clinical Microbiology and Infection. 17, 3, p. 386-394 9 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Cell Biology
Cervical Intraepithelial Neoplasia
Polymerase Chain Reaction
Human papillomavirus 18
3 Citations (Scopus)

Gene expression and behavior analysis of PC12 cells grown on biodegradable nano-fibrous membranes

Chang, S. F., Yang, C. P., Tai, C. C. & Tseng, H., Dec 2011, In : Current Nanoscience. 7, 6, p. 886-892 7 p.

Research output: Contribution to journalArticle

Fibrous membranes
PC12 Cells
Gene expression
Cells
Membranes
23 Citations (Scopus)

Integration of human papillomavirus correlates with high levels of viral oncogene transcripts in cervical carcinogenesis

Ho, C. M., Lee, B. H., Chang, S. F., Chien, T. Y., Huang, S. H., Yan, C. C. & Cheng, W. F., Nov 2011, In : Virus Research. 161, 2, p. 124-130 7 p.

Research output: Contribution to journalArticle

Human papillomavirus 16
Oncogenes
Uterine Cervical Neoplasms
Cell Biology
Real-Time Polymerase Chain Reaction
17 Citations (Scopus)
Macrophages
Nitric Oxide Synthase Type II
Granulocyte Colony-Stimulating Factor
Sirolimus
Lipopolysaccharides
12 Citations (Scopus)

Transformation of isosteviol lactam by Fungi and the suppressive effects of its transformed products on LPS-induced iNOS expression in macrophages

Chou, B. H., Yang, L. M., Chang, S. F., Hsu, F-L., Wang, L. H., Lin, W. K., Liu, P. C. & Lin, S. J., Jun 24 2011, In : Journal of Natural Products. 74, 6, p. 1379-1385 7 p.

Research output: Contribution to journalArticle

Lactams
Macrophages
Fungi
Aspergillus niger
Absidia
2010
15 Citations (Scopus)

Chymase mediates paraquat-induced collagen production in human lung fibroblasts

Lang, Y. D., Chang, S. F., Wang, L-F. & Chen, C. M., Mar 1 2010, In : Toxicology Letters. 193, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

Chymases
Paraquat
Fibroblasts
Collagen
Lung
18 Citations (Scopus)

Polymeric micelle gene delivery of bcl-xL via eye drop reduced corneal apoptosis following epithelial debridement

Tong, Y. C., Chang, S. F., Kao, W. W. Y., Liu, C. Y. & Liaw, J., Oct 2010, In : Journal of Controlled Release. 147, 1, p. 76-83 8 p.

Research output: Contribution to journalArticle

Ophthalmic Solutions
Micelles
Debridement
DNA Fragmentation
Apoptosis
16 Citations (Scopus)

Promoter methylation of sFRP5 in patients with ovarian clear cell adenocarcinomaARTICLE

Ho, C. M., Lai, H. C., Huang, S. H., Chien, T. Y., Lin, M. C. & Chang, S. F., Apr 2010, In : European Journal of Clinical Investigation. 40, 4, p. 310-318 9 p.

Research output: Contribution to journalArticle

Clear Cell Adenocarcinoma
Methylation
Genes
Tumor Suppressor Protein p14ARF
Cells
22 Citations (Scopus)

Type-specific human papillomavirus oncogene messenger RNA levels correlate with the severity of cervical neoplasia

Ho, C. M., Lee, B. H., Chang, S. F., Chien, T. Y., Huang, S. H., Yan, C. C. & Cheng, W. F., Aug 1 2010, In : International Journal of Cancer. 127, 3, p. 622-632 11 p.

Research output: Contribution to journalArticle

Oncogenes
Human papillomavirus 6
Messenger RNA
DNA
Real-Time Polymerase Chain Reaction
2009
17 Citations (Scopus)

Fungal transformation of isosteviol lactone and its biological evaluation for inhibiting the AP-1 transcription factor

Chou, B. H., Yang, L. M., Chang, S. F., Hsu, F. L., Lo, C. H., Lin, W. K., Wang, L. H., Liu, P. C. & Lin, S. J., Apr 2009, In : Phytochemistry. 70, 6, p. 759-764 6 p.

Research output: Contribution to journalArticle

Aspergillus niger
Diterpenes
Macrophages
Aspergillus
Transcription Factor AP-1
20 Citations (Scopus)

Microbial transformation of isosteviol oxime and the inhibitory effects on NF-κB and AP-1 activation in LPS-stimulated macrophages

Chang, S. F., Chou, B. H., Yang, L. M., Hsu, F. L., Lin, W. K., Ho, Y. & Lin, S. J., Sep 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 17, p. 6348-6353 6 p.

Research output: Contribution to journalArticle

Oximes
Macrophages
Transcription Factor AP-1
Chemical activation
Acids
8 Citations (Scopus)

Oral gene therapy for hypoparathyroidism: A rat model

Chou, F. F., Huang, S. C., Chang, S. F., Liaw, J. & Hung, P. H., Nov 1 2009, In : Human Gene Therapy. 20, 11, p. 1344-1350 7 p.

Research output: Contribution to journalArticle

Hypoparathyroidism
Parathyroid Hormone
Genetic Therapy
Complementary DNA
Edetic Acid
37 Citations (Scopus)

PTEN promoter methylation and LOH of 10q22-23 locus in PTEN expression of ovarian clear cell adenocarcinomas

Ho, C. M., Lin, M. C., Huang, S. H., Huang, C. J., Lai, H. C., Chien, T. Y. & Chang, S. F., Feb 2009, In : Gynecologic Oncology. 112, 2, p. 307-313 7 p.

Research output: Contribution to journalArticle

Clear Cell Adenocarcinoma
Loss of Heterozygosity
Phosphoric Monoester Hydrolases
Methylation
Tensins
14 Citations (Scopus)
trichostatin A
Nitric Oxide Synthase Type II
Lipopolysaccharides
Macrophages
Carrier Proteins
2008
19 Citations (Scopus)

Bioavailability effect of methylprednisolone by polymeric micelles

Chen, C. L., Chang, S. F., Lee, D., Yang, L. Y., Lee, Y-H., Hsu, C-Y., Lin, S. J. & Liaw, J., Jan 2008, In : Pharmaceutical Research. 25, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Methylprednisolone
Micelles
Biological Availability
Spinal Cord
Plasmas
70 Citations (Scopus)

Homocysteine inhibits arterial endothelial cell growth through transcriptional downregulation of fibroblast growth factor-2 involving G protein and DNA methylation

Chang, P. Y., Lu, S. C., Lee, C. M., Chen, Y. J., Dugan, T. A., Huang, W. H., Chang, S. F., Liao, W. S. L., Chen, C. H. & Lee, Y. T., Apr 2008, In : Circulation Research. 102, 8, p. 933-941 9 p.

Research output: Contribution to journalArticle

Homocysteine
Fibroblast Growth Factor 2
DNA Methylation
GTP-Binding Proteins
Down-Regulation
25 Citations (Scopus)

Inflammatory mediators of cerebrospinal fluid from patients with spinal cord injury

Tsai, M. C., Wei, C. P., Lee, D. Y., Tseng, Y. T., Tsai, M. D., Shih, Y. L., Lee, Y-H., Chang, S. F. & Leu, S. J., Dec 2008, In : Surgical Neurology. 70, SUPPL. 1

Research output: Contribution to journalArticle

Spinal Cord Injuries
Cerebrospinal Fluid
Therapeutics
Cytokines
Tissue Inhibitor of Metalloproteinase-1
31 Citations (Scopus)
response elements
Response Elements
Metabolites
glucocorticoids
androgens
12 Citations (Scopus)

Microbial transformation of isosteviol lactone and evaluation of the transformation products on androgen response element

Chou, B. H., Yang, L. M., Chang, S. F., Hsu, F-L., Lo, C. H., Liaw, J. H., Liu, P. C. & Lin, S. J., Apr 2008, In : Journal of Natural Products. 71, 4, p. 602-607 6 p.

Research output: Contribution to journalArticle

Aspergillus niger
response elements
Response Elements
Metabolites
androgens
34 Citations (Scopus)

Neuronal activity enhances aryl hydrocarbon receptor-mediated gene expression and dioxin neurotoxicity in cortical neurons

Lin, C. H., Juan, S. H., Wang, C. Y., Sun, Y. Y., Chou, C. M., Chang, S. F., Hu, S. Y., Lee, W. S. & Lee, Y-H., Mar 2008, In : Journal of Neurochemistry. 104, 5, p. 1415-1429 15 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Dioxins
Gene expression
Neurons
Gene Expression
2007
7 Citations (Scopus)

A novel role for Oct-2 in the lipopolysaccharide-mediated induction of resistin gene expression in RAW264.7 cells

Lu, S. C., Chang, S. F., Chen, H. L., Chou, Y. Y., Lan, Y. H., Chuang, C. Y., Yu, W. H. & Chen, C. L., Mar 1 2007, In : Biochemical Journal. 402, 2, p. 387-395 9 p.

Research output: Contribution to journalArticle

Resistin
Gene expression
Lipopolysaccharides
Gene Expression
Macrophages
11 Citations (Scopus)

Biotransformation of gallic acid by Beauveria sulfurescens ATCC 7159

Hsu, F-L., Yang, L. M., Chang, S. F., Wang, L. H., Hsu, C-Y., Liu, P. C. & Lin, S. J., Mar 2007, In : Applied Microbiology and Biotechnology. 74, 3, p. 659-666 8 p.

Research output: Contribution to journalArticle

Beauveria
Gallic Acid
Biotransformation
Metabolites
Pyrans
16 Citations (Scopus)

Ethanol enhanced in vivo gene delivery with non-ionic polymeric micelles inhalation

Chao, Y. C., Chang, S. F., Lu, S. C., Hwang, T. C., Hsieh, W. H. & Liaw, J., Mar 12 2007, In : Journal of Controlled Release. 118, 1, p. 105-117 13 p.

Research output: Contribution to journalArticle

Micelles
Inhalation
Ethanol
Genes
Cystic Fibrosis