If you made any changes in Pure these will be visible here soon.

Research Output 1989 2018

  • 1870 Citations
  • 23 h-Index
  • 79 Article
Article
6 Citations (Scopus)

AMPK-dependent and independent actions of P2X7 in regulation of mitochondrial and lysosomal functions in microglia

Sekar, P., Huang, D. Y., Hsieh, S. L., Chang, S. F. & Lin, W. W., Nov 20 2018, In : Cell Communication and Signaling. 16, 1, 83.

Research output: Contribution to journalArticle

Mitochondrial Degradation
AMP-Activated Protein Kinases
Microglia
Mitochondrial Dynamics
Chemical activation
5 Citations (Scopus)

Analysis of the CYP21A2 gene with intergenic recombination and multiple gene deletions in the RCCX module

Chang, S. F. & Lee, H. H., Jan 1 2011, In : Genetic Testing and Molecular Biomarkers. 15, 1-2, p. 35-42 8 p.

Research output: Contribution to journalArticle

Gene Deletion
Genetic Recombination
Southern Blotting
Mutation
Genes

A Novel Nonsense Mutation at the Human PTCH Gene in a Patient with Nevoid Basal Cell Carcinoma

Cheng, K-L., Chang, S-F., Hu, C-H. & Lee, W-R., 2000, In : Dermatologica Sinica. 18, 3, p. 255-259 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A novel role for Oct-2 in the lipopolysaccharide-mediated induction of resistin gene expression in RAW264.7 cells

Lu, S. C., Chang, S. F., Chen, H. L., Chou, Y. Y., Lan, Y. H., Chuang, C. Y., Yu, W. H. & Chen, C. L., Mar 1 2007, In : Biochemical Journal. 402, 2, p. 387-395 9 p.

Research output: Contribution to journalArticle

Resistin
Gene expression
Lipopolysaccharides
Gene Expression
Macrophages
3 Citations (Scopus)

Anti-apoptotic gene delivery with cyclo-(D-Trp-Tyr) peptide nanotube via eye drop following corneal epithelial debridement

Lee, Y. H., Chang, S. F. & Liaw, J., Jul 17 2015, In : Pharmaceutics. 7, 3, p. 122-136 15 p.

Research output: Contribution to journalArticle

tryptophyltyrosine
Peptide Nanotubes
Ophthalmic Solutions
Debridement
Genes
21 Citations (Scopus)

Arctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes

Tsai, W. J., Chang, C. T., Wang, G. J., Li, Z-H., Chang, S. F., Lu, S. C. & Kuo, Y. C., Mar 25 2011, In : Chinese Medicine. 6, 12.

Research output: Contribution to journalArticle

Arctium
Interferons
Interleukin-2
T-Lymphocytes
Gene Expression
33 Citations (Scopus)

Aspirin protects human coronary artery endothelial cells against atherogenic electronegative LDL via an epigenetic mechanism: A novel cytoprotective role of aspirin in acute myocardial infarction

Chang, P. Y., Chen, Y. J., Chang, F. H., Lu, J., Huang, W. H., Yang, T. C., Lee, Y. T., Chang, S. F., Lu, S. C. & Chen, C. H., Jul 1 2013, In : Cardiovascular Research. 99, 1, p. 137-145 9 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Epigenomics
Aspirin
Coronary Vessels
Endothelial Cells
72 Citations (Scopus)

Assaying for structural variation in the parvovirus capsid and its role in infection

Weichert, W. S., Parker, J. S. L., Wahid, A. T. M., Chang, S. F., Meier, E. & Parrish, C. R., Oct 10 1998, In : Virology. 250, 1, p. 106-117 12 p.

Research output: Contribution to journalArticle

Parvovirus
Capsid
Infection
Canine Parvovirus
Subtilisin
13 Citations (Scopus)

Bcl-2 gene family expression in the brain of rat offspring after gestational and lactational dioxin exposure

Chang, S. F., Sun, Y. Y., Yang, L. Y., Hu, S. Y., Tsai, S-Y., Lee, W. S. & Lee, Y-H., 2005, In : Annals of the New York Academy of Sciences. 1042, p. 471-480 10 p.

Research output: Contribution to journalArticle

bcl-2 Genes
Dioxins
Rats
Brain
Genes
19 Citations (Scopus)

Bioavailability effect of methylprednisolone by polymeric micelles

Chen, C. L., Chang, S. F., Lee, D., Yang, L. Y., Lee, Y-H., Hsu, C-Y., Lin, S. J. & Liaw, J., Jan 2008, In : Pharmaceutical Research. 25, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Methylprednisolone
Micelles
Biological Availability
Spinal Cord
Plasmas

Biotransformation of dihydroisosteviol and the effects of transformed products on steroidogenic gene expressions

Chang, S. F., Yang, L. M., Huang, T. J., Chen, C. Y., Sheu, S. Y., Liu, P. C. & Lin, S. J., Nov 2013, In : Phytochemistry. 95, p. 268-276 9 p.

Research output: Contribution to journalArticle

Biotransformation
biotransformation
Gene expression
Steroidogenic Factor 1
Gene Expression
11 Citations (Scopus)

Biotransformation of gallic acid by Beauveria sulfurescens ATCC 7159

Hsu, F-L., Yang, L. M., Chang, S. F., Wang, L. H., Hsu, C-Y., Liu, P. C. & Lin, S. J., Mar 2007, In : Applied Microbiology and Biotechnology. 74, 3, p. 659-666 8 p.

Research output: Contribution to journalArticle

Beauveria
Gallic Acid
Biotransformation
Metabolites
Pyrans
15 Citations (Scopus)

Chymase mediates paraquat-induced collagen production in human lung fibroblasts

Lang, Y. D., Chang, S. F., Wang, L-F. & Chen, C. M., Mar 1 2010, In : Toxicology Letters. 193, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

Chymases
Paraquat
Fibroblasts
Collagen
Lung

Clinical performance of multiplex high-risk e6 mrna expression in comparison with hpv dna subtypes for the identification of women at risk of cervical cancer

Ho, C. M., Pan, K. Y., Chen, Y. Y., Huang, C. Y., Chen, Y. L. & Chang, S. F., Aug 1 2015, In : Journal of Medical Virology. 87, 8, p. 1404-1412 9 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
RNA
DNA
Odds Ratio
Confidence Intervals
3 Citations (Scopus)

Clinical significance of signal pattern of high-risk human papillomavirus using a novel fluorescence in situ hybridization assay in cervical cytology

Ho, C. M., Lee, B. H., Chang, S. F., Chien, T. Y., Huang, S. H., Yan, C. C. & Cheng, W. F., Mar 2011, In : Clinical Microbiology and Infection. 17, 3, p. 386-394 9 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Cell Biology
Cervical Intraepithelial Neoplasia
Polymerase Chain Reaction
Human papillomavirus 18
3 Citations (Scopus)

Coordinate effects of P2X7 and extracellular acidification in microglial cells

Sekar, P., Huang, D. Y., Chang, S. F. & Lin, W. W., Jan 1 2018, In : Oncotarget. 9, 16, p. 12718-12731 14 p.

Research output: Contribution to journalArticle

Adenosine Triphosphate
Reactive Oxygen Species
Nigericin
Mitochondrial Dynamics
Inflammation
22 Citations (Scopus)

Deletion of the C4-CYP21 repeat module leading to the formation of a chimeric CYP21P/CYP21 gene in a 9.3-kb fragment as a cause of steroid 21-hydroxylase deficiency

Lee, H. H., Chang, S. F., Lee, Y. J., Raskin, S., Lin, S. J., Chao, M. C., Lo, F. S. & Lin, C. Y., Feb 1 2003, In : Clinical Chemistry. 49, 2, p. 319-322 4 p.

Research output: Contribution to journalArticle

Steroid 21-Hydroxylase
Nucleic Acid Repetitive Sequences
Gene Deletion
Southern Blotting
Genetic Recombination
3 Citations (Scopus)

Demethylation of HIN-1 reverses paclitaxel-resistance of ovarian clear cell carcinoma through the AKT-mTOR signaling pathway

Ho, C. M., Huang, C. J., Huang, S. H., Chang, S. F. & Cheng, W. F., Oct 24 2015, In : BMC Cancer. 15, 1, 789.

Research output: Contribution to journalArticle

Paclitaxel
Carcinoma
Methylation
Cell Line
decitabine
29 Citations (Scopus)

Detection and quantitation of human papillomavirus type 16, 18 and 52 DNA in the peripheral blood of cervical cancer patients

Ho, C. M., Yang, S. S., Chien, T. Y., Huang, S. H., Jeng, C. J. & Chang, S. F., Dec 2005, In : Gynecologic Oncology. 99, 3, p. 615-621 7 p.

Research output: Contribution to journalArticle

Human papillomavirus 18
Human papillomavirus 16
Uterine Cervical Neoplasms
Cervical Intraepithelial Neoplasia
DNA
64 Citations (Scopus)

Difference in transcriptional activity of two homologous CYP21A genes

Chang, S. F. & Chung, B. C., 1995, In : Molecular Endocrinology. 9, 10, p. 1330-1336 7 p.

Research output: Contribution to journalArticle

Genes
Nucleotides
Sp1 Transcription Factor
Steroid 21-Hydroxylase
Congenital Adrenal Hyperplasia
108 Citations (Scopus)

Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death

Lee, H. H., Yang, L-L., Wang, C. C., Hu, S. Y., Chang, S. F. & Lee, Y-H., Oct 3 2003, In : Brain Research. 986, 1-2, p. 103-113 11 p.

Research output: Contribution to journalArticle

Polyphenols
Glutamic Acid
L-Lactate Dehydrogenase
Neurons
Glucose
6 Citations (Scopus)

Duplication of 111 bases in exon 1 of the CYP21 gene is combined with deletion of CYP21P-C4B genes in steroid 21-hydroxylase deficiency

Lee, H. H., Chang, S. F., Lo, F. S., Chao, H. T. & Lin, C. Y., Jul 1 2003, In : Molecular Genetics and Metabolism. 79, 3, p. 214-220 7 p.

Research output: Contribution to journalArticle

Steroid 21-Hydroxylase
Exons
Genes
Congenital Adrenal Hyperplasia
Codon
5 Citations (Scopus)

Electronegative LDL is linked to high-fat, high-cholesterol diet-induced nonalcoholic steatohepatitis in hamsters

Lai, Y. S., Yang, T. C., Chang, P. Y., Chang, S. F., Ho, S. L., Chen, H. L. & Lu, S. C., Apr 1 2016, In : Journal of Nutritional Biochemistry. 30, p. 44-52 9 p.

Research output: Contribution to journalArticle

High Fat Diet
Nutrition
Cricetinae
Fats
Cholesterol
12 Citations (Scopus)
Toxocara canis
Nitric Oxide Synthase Type II
Hepatitis
Larva
Leukocytes
5 Citations (Scopus)
Cefazolin
Agglutination
Polysaccharides
Erythrocytes
Escherichia coli
16 Citations (Scopus)

Ethanol enhanced in vivo gene delivery with non-ionic polymeric micelles inhalation

Chao, Y. C., Chang, S. F., Lu, S. C., Hwang, T. C., Hsieh, W. H. & Liaw, J., Mar 12 2007, In : Journal of Controlled Release. 118, 1, p. 105-117 13 p.

Research output: Contribution to journalArticle

Micelles
Inhalation
Ethanol
Genes
Cystic Fibrosis
169 Citations (Scopus)

Evolution of the feline-subgroup parvoviruses and the control of canine host range in vivo

Truyen, U., Gruenberg, A., Chang, S. F., Obermaier, B., Veijalainen, P. & Parrish, C. R., 1995, In : Journal of Virology. 69, 8, p. 4702-4710 9 p.

Research output: Contribution to journalArticle

Parvoviridae
Feline Panleukopenia Virus
Host Specificity
host range
Canidae
5 Citations (Scopus)

Extracellular signal-regulated kinase 2 mediates the expression of granulocyte colony-stimulating factor in invasive cancer cells

Lee, C. H., Lin, S. H., Chang, S. F., Chang, P. Y., Yang, Z. P. & Lu, S. C., Jul 2013, In : Oncology Reports. 30, 1, p. 419-424 6 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 1
Granulocyte Colony-Stimulating Factor
Neoplasms
Tumor Necrosis Factor-alpha
Blood Circulation
48 Citations (Scopus)

Eye drop delivery of nano-polymeric micelle formulated genes with cornea-specific promoters

Tong, Y. C., Chang, S. F., Liu, C. Y., Kao, W. W. Y., Huang, C. H. & Liaw, J., Nov 2007, In : Journal of Gene Medicine. 9, 11, p. 956-966 11 p.

Research output: Contribution to journalArticle

Ophthalmic Solutions
Micelles
Cornea
Genes
Keratin-12
17 Citations (Scopus)

Fungal transformation of isosteviol lactone and its biological evaluation for inhibiting the AP-1 transcription factor

Chou, B. H., Yang, L. M., Chang, S. F., Hsu, F. L., Lo, C. H., Lin, W. K., Wang, L. H., Liu, P. C. & Lin, S. J., Apr 2009, In : Phytochemistry. 70, 6, p. 759-764 6 p.

Research output: Contribution to journalArticle

Aspergillus niger
Diterpenes
Macrophages
Aspergillus
Transcription Factor AP-1
3 Citations (Scopus)

Gene expression and behavior analysis of PC12 cells grown on biodegradable nano-fibrous membranes

Chang, S. F., Yang, C. P., Tai, C. C. & Tseng, H., Dec 2011, In : Current Nanoscience. 7, 6, p. 886-892 7 p.

Research output: Contribution to journalArticle

Fibrous membranes
PC12 Cells
Gene expression
Cells
Membranes
2 Citations (Scopus)

Gene expression and behavior analysis of PC12 cells grown on synthetic biodegradable fibrous membranes coated with natural biopolymers

Tsai, T. H., Tai, C. C., Wu, Y. H. S., Hung, S. H., Chang, S. F., Yang, C. P. & Tseng, H., 2014, In : Current Nanoscience. 10, 2, p. 235-242 8 p.

Research output: Contribution to journalArticle

Fibrous membranes
Biopolymers
PC12 Cells
Gene expression
Cells
4 Citations (Scopus)

Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis

Ho, C. M., Shih, T-B., Hsiao, C. C., Huang, S. H., Chang, S-F. & Cheng, W. F., Nov 23 2015, In : Journal of Translational Medicine. 13, 1, 367.

Research output: Contribution to journalArticle

Methylation
Stromal Cells
Tumors
Carcinogenesis
Stem Cells
70 Citations (Scopus)

Homocysteine inhibits arterial endothelial cell growth through transcriptional downregulation of fibroblast growth factor-2 involving G protein and DNA methylation

Chang, P. Y., Lu, S. C., Lee, C. M., Chen, Y. J., Dugan, T. A., Huang, W. H., Chang, S. F., Liao, W. S. L., Chen, C. H. & Lee, Y. T., Apr 2008, In : Circulation Research. 102, 8, p. 933-941 9 p.

Research output: Contribution to journalArticle

Homocysteine
Fibroblast Growth Factor 2
DNA Methylation
GTP-Binding Proteins
Down-Regulation
27 Citations (Scopus)

Human papillomaviral load changes in low-grade squamous intraepithelial lesions of the uterine cervix

Ho, C. M., Cheng, W. F., Chu, T. Y., Chen, C. A., Chuang, M. H., Chang, S. F. & Hsieh, C. Y., Nov 20 2006, In : British Journal of Cancer. 95, 10, p. 1384-1389 6 p.

Research output: Contribution to journalArticle

Cervix Uteri
Viral Load
Papillomavirus Infections
Human papillomavirus 16
DNA
8 Citations (Scopus)

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method

Lee, H. H., Chang, S. F., Tseng, Y. T. & Lee, Y. J., Oct 1 2006, In : Analytical Biochemistry. 357, 1, p. 122-127 6 p.

Research output: Contribution to journalArticle

Polymerase chain reaction
Amplification
Epitopes
Genes
Polymerase Chain Reaction
Congenital Adrenal Hyperplasia
Genome
Genes
Mutation
Androgens
25 Citations (Scopus)

Inflammatory mediators of cerebrospinal fluid from patients with spinal cord injury

Tsai, M. C., Wei, C. P., Lee, D. Y., Tseng, Y. T., Tsai, M. D., Shih, Y. L., Lee, Y-H., Chang, S. F. & Leu, S. J., Dec 2008, In : Surgical Neurology. 70, SUPPL. 1

Research output: Contribution to journalArticle

Spinal Cord Injuries
Cerebrospinal Fluid
Therapeutics
Cytokines
Tissue Inhibitor of Metalloproteinase-1
35 Citations (Scopus)
GAP-43 Protein
Janus Kinases
STAT3 Transcription Factor
Spinal Ganglia
Neurites
67 Citations (Scopus)

Integrated human papillomavirus types 52 and 58 are infrequently found in cervical cancer, and high viral loads predict risk of cervical cancer

Ho, C. M., Chien, T. Y., Huang, S. H., Lee, B. H. & Chang, S. F., Jul 2006, In : Gynecologic Oncology. 102, 1, p. 54-60 7 p.

Research output: Contribution to journalArticle

Viral Load
Uterine Cervical Neoplasms
DNA
Human papillomavirus 18
Cervical Intraepithelial Neoplasia
23 Citations (Scopus)

Integration of human papillomavirus correlates with high levels of viral oncogene transcripts in cervical carcinogenesis

Ho, C. M., Lee, B. H., Chang, S. F., Chien, T. Y., Huang, S. H., Yan, C. C. & Cheng, W. F., Nov 2011, In : Virus Research. 161, 2, p. 124-130 7 p.

Research output: Contribution to journalArticle

Human papillomavirus 16
Oncogenes
Uterine Cervical Neoplasms
Cell Biology
Real-Time Polymerase Chain Reaction
2 Citations (Scopus)

In vitro and in vivo assessment of delivery of hydrophobic molecules and plasmid DNAs with PEO-PPO-PEO polymeric micelles on cornea

Hsiao, F., Huang, P. Y., Aoyagi, T., Chang, S. F. & Liaw, J., Apr 2018, In : Journal of Food and Drug Analysis. 26, 2, p. 869-878

Research output: Contribution to journalArticle

rhodamine B
Energy Transfer
Micelles
cornea
micelles
94 Citations (Scopus)
Ophthalmic Solutions
Micelles
Genes
Gene Expression
DNA
35 Citations (Scopus)

Isolation and characterization of stromal progenitor cells from ascites of patients with epithelial ovarian adenocarcinoma

Ho, C. M., Chang, S-F., Hsiao, C. C., Chien, T. Y. & Shih, T-B., 2012, In : Journal of Biomedical Science. 19, 1, 23.

Research output: Contribution to journalArticle

Stromal Cells
Ascites
Adenocarcinoma
Stem Cells
Cells
7 Citations (Scopus)

LPS-induced G-CSF expression in macrophages is mediated by ERK2, but not ERK1

Chang, S. F., Lin, S. S., Yang, H. C., Chou, Y. Y., Gao, J. I. & Lu, S. C., Jun 26 2015, In : PLoS One. 10, 6, e0129685.

Research output: Contribution to journalArticle

granulocyte colony-stimulating factor
Macrophages
Granulocyte Colony-Stimulating Factor
lipopolysaccharides
Lipopolysaccharides
20 Citations (Scopus)

Malondialdehyde mediates oxidized LDL-induced coronary toxicity through the Akt-FGF2 pathway via DNA methylation

Yang, T. C., Chen, Y. J., Chang, S. F., Chen, C. H., Chang, P. Y. & Lu, S. C., Feb 3 2014, In : Journal of Biomedical Science. 21, 1, 11.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
DNA Methylation
Malondialdehyde
Toxicity
Endothelial cells
16 Citations (Scopus)

Microbial metabolism of steviol and steviol-16α,17-epoxide

Yang, L. M., Hsu, F-L., Chang, S. F., Cheng, J. T., Hsu, J. Y., Hsu, C-Y., Liu, P. C. & Lin, S. J., Feb 2007, In : Phytochemistry. 68, 4, p. 562-570 9 p.

Research output: Contribution to journalArticle

steviol
Epoxy Compounds
epoxides
Metabolism
Acids
31 Citations (Scopus)
response elements
Response Elements
Metabolites
glucocorticoids
androgens
13 Citations (Scopus)

Microbial transformation of isosteviol lactone and evaluation of the transformation products on androgen response element

Chou, B. H., Yang, L. M., Chang, S. F., Hsu, F-L., Lo, C. H., Liaw, J. H., Liu, P. C. & Lin, S. J., Apr 2008, In : Journal of Natural Products. 71, 4, p. 602-607 6 p.

Research output: Contribution to journalArticle

Aspergillus niger
response elements
Response Elements
Metabolites
androgens
21 Citations (Scopus)

Microbial transformation of isosteviol oxime and the inhibitory effects on NF-κB and AP-1 activation in LPS-stimulated macrophages

Chang, S. F., Chou, B. H., Yang, L. M., Hsu, F. L., Lin, W. K., Ho, Y. & Lin, S. J., Sep 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 17, p. 6348-6353 6 p.

Research output: Contribution to journalArticle

Oximes
Macrophages
Transcription Factor AP-1
Chemical activation
Acids