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Research Output 1989 2018

  • 1869 Citations
  • 23 h-Index
  • 79 Article
1989
1 Citation (Scopus)

The subtypes, distribution and location of human papillomavirus DNA in Genital warts and Genital Bowen's disease - a study using in situ DNA.DNA hybridization

Jee, S. H., Chen, Y., Chang, S. F., Ho, S. W., Wu, Y. C., Wen, W. N. & Lu, Y. C., 1989, In : Chinese Journal of Microbiology and Immunology. 22, 4, p. 267-277 11 p.

Research output: Contribution to journalArticle

Bowen's Disease
Human papillomavirus 6
Condylomata Acuminata
Human papillomavirus 11
Human papillomavirus 18
1992
154 Citations (Scopus)
Canine Parvovirus
Carnivore protoparvovirus 1
capsid
Capsid
Host Specificity
70 Citations (Scopus)

Mutations adjacent to the dimple of the canine parvovirus capsid structure affect sialic acid binding

Barbis, D. P., Chang, S. F. & Parrish, C. R., 1992, In : Virology. 191, 1, p. 301-308 8 p.

Research output: Contribution to journalArticle

Canine Parvovirus
Capsid
N-Acetylneuraminic Acid
Erythrocytes
Virus Attachment
1995
64 Citations (Scopus)

Difference in transcriptional activity of two homologous CYP21A genes

Chang, S. F. & Chung, B. C., 1995, In : Molecular Endocrinology. 9, 10, p. 1330-1336 7 p.

Research output: Contribution to journalArticle

Genes
Nucleotides
Sp1 Transcription Factor
Steroid 21-Hydroxylase
Congenital Adrenal Hyperplasia
169 Citations (Scopus)

Evolution of the feline-subgroup parvoviruses and the control of canine host range in vivo

Truyen, U., Gruenberg, A., Chang, S. F., Obermaier, B., Veijalainen, P. & Parrish, C. R., 1995, In : Journal of Virology. 69, 8, p. 4702-4710 9 p.

Research output: Contribution to journalArticle

Parvoviridae
Feline Panleukopenia Virus
Host Specificity
host range
Canidae
1996
31 Citations (Scopus)

The common I172N mutation causes conformational change of cytochrome P450c21 revealed by systematic mutation, kinetic, and structural studies

Hsu, L. C., Hsu, N. C., Guzova, J. A., Guzov, V. M., Chang, S. F. & Chung, B. C., Feb 9 1996, In : Journal of Biological Chemistry. 271, 6, p. 3306-3310 5 p.

Research output: Contribution to journalArticle

Steroid 21-Hydroxylase
Mutation
Kinetics
Proteins
Substitution reactions
1998
72 Citations (Scopus)

Assaying for structural variation in the parvovirus capsid and its role in infection

Weichert, W. S., Parker, J. S. L., Wahid, A. T. M., Chang, S. F., Meier, E. & Parrish, C. R., Oct 10 1998, In : Virology. 250, 1, p. 106-117 12 p.

Research output: Contribution to journalArticle

Parvovirus
Capsid
Infection
Canine Parvovirus
Subtilisin
13 Citations (Scopus)

The -104G nucleotide of the human CYP21 gene is important for CYP21 transcription activity and protein interaction

Chin, K. K. & Chang, S. F., Apr 15 1998, In : Nucleic Acids Research. 26, 8, p. 1959-1964 6 p.

Research output: Contribution to journalArticle

Nucleotides
Pseudogenes
Genes
Proteins
Nuclear Proteins
8 Citations (Scopus)
PC12 Cells
Opioid Receptors
Pheochromocytoma
Nerve Growth Factor
Naloxone
2 Citations (Scopus)

The suppression effect of DNA sequences within the C4A region on the transcription activity of human CYP21

Chang, S. F. & Cheng, C. L., 1998, In : Endocrine Research. 24, 3-4, p. 625-630 6 p.

Research output: Contribution to journalArticle

Human Activities
Genes
Leydig Cell Tumor
Complement C4
Pseudogenes
2000

A Novel Nonsense Mutation at the Human PTCH Gene in a Patient with Nevoid Basal Cell Carcinoma

Cheng, K-L., Chang, S-F., Hu, C-H. & Lee, W-R., 2000, In : Dermatologica Sinica. 18, 3, p. 255-259 5 p.

Research output: Contribution to journalArticle

2001
94 Citations (Scopus)
Ophthalmic Solutions
Micelles
Genes
Gene Expression
DNA
12 Citations (Scopus)
Introns
Exons
RNA Splice Sites
COS Cells
Mutation
6 Citations (Scopus)
delta Opioid Receptor
PC12 Cells
Pheochromocytoma
Nerve Growth Factor
Poisons
2003
22 Citations (Scopus)

Deletion of the C4-CYP21 repeat module leading to the formation of a chimeric CYP21P/CYP21 gene in a 9.3-kb fragment as a cause of steroid 21-hydroxylase deficiency

Lee, H. H., Chang, S. F., Lee, Y. J., Raskin, S., Lin, S. J., Chao, M. C., Lo, F. S. & Lin, C. Y., Feb 1 2003, In : Clinical Chemistry. 49, 2, p. 319-322 4 p.

Research output: Contribution to journalArticle

Steroid 21-Hydroxylase
Nucleic Acid Repetitive Sequences
Gene Deletion
Southern Blotting
Genetic Recombination
108 Citations (Scopus)

Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death

Lee, H. H., Yang, L-L., Wang, C. C., Hu, S. Y., Chang, S. F. & Lee, Y-H., Oct 3 2003, In : Brain Research. 986, 1-2, p. 103-113 11 p.

Research output: Contribution to journalArticle

Polyphenols
Glutamic Acid
L-Lactate Dehydrogenase
Neurons
Glucose
6 Citations (Scopus)

Duplication of 111 bases in exon 1 of the CYP21 gene is combined with deletion of CYP21P-C4B genes in steroid 21-hydroxylase deficiency

Lee, H. H., Chang, S. F., Lo, F. S., Chao, H. T. & Lin, C. Y., Jul 1 2003, In : Molecular Genetics and Metabolism. 79, 3, p. 214-220 7 p.

Research output: Contribution to journalArticle

Steroid 21-Hydroxylase
Exons
Genes
Congenital Adrenal Hyperplasia
Codon
15 Citations (Scopus)
Steroid 21-Hydroxylase
Genes
Mutation
Congenital Adrenal Hyperplasia
Haplotypes
2004
12 Citations (Scopus)
Toxocara canis
Nitric Oxide Synthase Type II
Hepatitis
Larva
Leukocytes
31 Citations (Scopus)

Nonionic polymeric micelles for oral gene delivery in vivo

Chang, S. F., Chang, H. Y., Tong, Y. C., Chen, S. H., Hsaio, F. C., Lu, S. C. & Liaw, J., May 2004, In : Human Gene Therapy. 15, 5, p. 481-493 13 p.

Research output: Contribution to journalArticle

Micelles
DNA
Genes
Lac Operon
Duodenum
2005
13 Citations (Scopus)

Bcl-2 gene family expression in the brain of rat offspring after gestational and lactational dioxin exposure

Chang, S. F., Sun, Y. Y., Yang, L. Y., Hu, S. Y., Tsai, S-Y., Lee, W. S. & Lee, Y-H., 2005, In : Annals of the New York Academy of Sciences. 1042, p. 471-480 10 p.

Research output: Contribution to journalArticle

bcl-2 Genes
Dioxins
Rats
Brain
Genes
29 Citations (Scopus)

Detection and quantitation of human papillomavirus type 16, 18 and 52 DNA in the peripheral blood of cervical cancer patients

Ho, C. M., Yang, S. S., Chien, T. Y., Huang, S. H., Jeng, C. J. & Chang, S. F., Dec 2005, In : Gynecologic Oncology. 99, 3, p. 615-621 7 p.

Research output: Contribution to journalArticle

Human papillomavirus 18
Human papillomavirus 16
Uterine Cervical Neoplasms
Cervical Intraepithelial Neoplasia
DNA
2006
27 Citations (Scopus)

Human papillomaviral load changes in low-grade squamous intraepithelial lesions of the uterine cervix

Ho, C. M., Cheng, W. F., Chu, T. Y., Chen, C. A., Chuang, M. H., Chang, S. F. & Hsieh, C. Y., Nov 20 2006, In : British Journal of Cancer. 95, 10, p. 1384-1389 6 p.

Research output: Contribution to journalArticle

Cervix Uteri
Viral Load
Papillomavirus Infections
Human papillomavirus 16
DNA
8 Citations (Scopus)

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method

Lee, H. H., Chang, S. F., Tseng, Y. T. & Lee, Y. J., Oct 1 2006, In : Analytical Biochemistry. 357, 1, p. 122-127 6 p.

Research output: Contribution to journalArticle

Polymerase chain reaction
Amplification
Epitopes
Genes
Polymerase Chain Reaction
67 Citations (Scopus)

Integrated human papillomavirus types 52 and 58 are infrequently found in cervical cancer, and high viral loads predict risk of cervical cancer

Ho, C. M., Chien, T. Y., Huang, S. H., Lee, B. H. & Chang, S. F., Jul 2006, In : Gynecologic Oncology. 102, 1, p. 54-60 7 p.

Research output: Contribution to journalArticle

Viral Load
Uterine Cervical Neoplasms
DNA
Human papillomavirus 18
Cervical Intraepithelial Neoplasia
16 Citations (Scopus)

Transformation of steviol-16α,17-epoxide by Streptomyces griseus and Cunninghamella bainieri

Chang, S. F., Yang, L. M., Hsu, F-L., Hsu, J. Y., Liaw, J. H. & Lin, S. J., Oct 2006, In : Journal of Natural Products. 69, 10, p. 1450-1455 6 p.

Research output: Contribution to journalArticle

Cunninghamella
steviol
Streptomyces griseus
Epoxy Compounds
Metabolites
2007
7 Citations (Scopus)

A novel role for Oct-2 in the lipopolysaccharide-mediated induction of resistin gene expression in RAW264.7 cells

Lu, S. C., Chang, S. F., Chen, H. L., Chou, Y. Y., Lan, Y. H., Chuang, C. Y., Yu, W. H. & Chen, C. L., Mar 1 2007, In : Biochemical Journal. 402, 2, p. 387-395 9 p.

Research output: Contribution to journalArticle

Resistin
Gene expression
Lipopolysaccharides
Gene Expression
Macrophages
11 Citations (Scopus)

Biotransformation of gallic acid by Beauveria sulfurescens ATCC 7159

Hsu, F-L., Yang, L. M., Chang, S. F., Wang, L. H., Hsu, C-Y., Liu, P. C. & Lin, S. J., Mar 2007, In : Applied Microbiology and Biotechnology. 74, 3, p. 659-666 8 p.

Research output: Contribution to journalArticle

Beauveria
Gallic Acid
Biotransformation
Metabolites
Pyrans
16 Citations (Scopus)

Ethanol enhanced in vivo gene delivery with non-ionic polymeric micelles inhalation

Chao, Y. C., Chang, S. F., Lu, S. C., Hwang, T. C., Hsieh, W. H. & Liaw, J., Mar 12 2007, In : Journal of Controlled Release. 118, 1, p. 105-117 13 p.

Research output: Contribution to journalArticle

Micelles
Inhalation
Ethanol
Genes
Cystic Fibrosis
48 Citations (Scopus)

Eye drop delivery of nano-polymeric micelle formulated genes with cornea-specific promoters

Tong, Y. C., Chang, S. F., Liu, C. Y., Kao, W. W. Y., Huang, C. H. & Liaw, J., Nov 2007, In : Journal of Gene Medicine. 9, 11, p. 956-966 11 p.

Research output: Contribution to journalArticle

Ophthalmic Solutions
Micelles
Cornea
Genes
Keratin-12
35 Citations (Scopus)
GAP-43 Protein
Janus Kinases
STAT3 Transcription Factor
Spinal Ganglia
Neurites
16 Citations (Scopus)

Microbial metabolism of steviol and steviol-16α,17-epoxide

Yang, L. M., Hsu, F-L., Chang, S. F., Cheng, J. T., Hsu, J. Y., Hsu, C-Y., Liu, P. C. & Lin, S. J., Feb 2007, In : Phytochemistry. 68, 4, p. 562-570 9 p.

Research output: Contribution to journalArticle

steviol
Epoxy Compounds
epoxides
Metabolism
Acids
2008
19 Citations (Scopus)

Bioavailability effect of methylprednisolone by polymeric micelles

Chen, C. L., Chang, S. F., Lee, D., Yang, L. Y., Lee, Y-H., Hsu, C-Y., Lin, S. J. & Liaw, J., Jan 2008, In : Pharmaceutical Research. 25, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Methylprednisolone
Micelles
Biological Availability
Spinal Cord
Plasmas
70 Citations (Scopus)

Homocysteine inhibits arterial endothelial cell growth through transcriptional downregulation of fibroblast growth factor-2 involving G protein and DNA methylation

Chang, P. Y., Lu, S. C., Lee, C. M., Chen, Y. J., Dugan, T. A., Huang, W. H., Chang, S. F., Liao, W. S. L., Chen, C. H. & Lee, Y. T., Apr 2008, In : Circulation Research. 102, 8, p. 933-941 9 p.

Research output: Contribution to journalArticle

Homocysteine
Fibroblast Growth Factor 2
DNA Methylation
GTP-Binding Proteins
Down-Regulation
25 Citations (Scopus)

Inflammatory mediators of cerebrospinal fluid from patients with spinal cord injury

Tsai, M. C., Wei, C. P., Lee, D. Y., Tseng, Y. T., Tsai, M. D., Shih, Y. L., Lee, Y-H., Chang, S. F. & Leu, S. J., Dec 2008, In : Surgical Neurology. 70, SUPPL. 1

Research output: Contribution to journalArticle

Spinal Cord Injuries
Cerebrospinal Fluid
Therapeutics
Cytokines
Tissue Inhibitor of Metalloproteinase-1
31 Citations (Scopus)
response elements
Response Elements
Metabolites
glucocorticoids
androgens
13 Citations (Scopus)

Microbial transformation of isosteviol lactone and evaluation of the transformation products on androgen response element

Chou, B. H., Yang, L. M., Chang, S. F., Hsu, F-L., Lo, C. H., Liaw, J. H., Liu, P. C. & Lin, S. J., Apr 2008, In : Journal of Natural Products. 71, 4, p. 602-607 6 p.

Research output: Contribution to journalArticle

Aspergillus niger
response elements
Response Elements
Metabolites
androgens
36 Citations (Scopus)

Neuronal activity enhances aryl hydrocarbon receptor-mediated gene expression and dioxin neurotoxicity in cortical neurons

Lin, C. H., Juan, S. H., Wang, C. Y., Sun, Y. Y., Chou, C. M., Chang, S. F., Hu, S. Y., Lee, W. S. & Lee, Y-H., Mar 2008, In : Journal of Neurochemistry. 104, 5, p. 1415-1429 15 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Dioxins
Gene expression
Neurons
Gene Expression
2009
17 Citations (Scopus)

Fungal transformation of isosteviol lactone and its biological evaluation for inhibiting the AP-1 transcription factor

Chou, B. H., Yang, L. M., Chang, S. F., Hsu, F. L., Lo, C. H., Lin, W. K., Wang, L. H., Liu, P. C. & Lin, S. J., Apr 2009, In : Phytochemistry. 70, 6, p. 759-764 6 p.

Research output: Contribution to journalArticle

Aspergillus niger
Diterpenes
Macrophages
Aspergillus
Transcription Factor AP-1
21 Citations (Scopus)

Microbial transformation of isosteviol oxime and the inhibitory effects on NF-κB and AP-1 activation in LPS-stimulated macrophages

Chang, S. F., Chou, B. H., Yang, L. M., Hsu, F. L., Lin, W. K., Ho, Y. & Lin, S. J., Sep 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 17, p. 6348-6353 6 p.

Research output: Contribution to journalArticle

Oximes
Macrophages
Transcription Factor AP-1
Chemical activation
Acids
8 Citations (Scopus)

Oral gene therapy for hypoparathyroidism: A rat model

Chou, F. F., Huang, S. C., Chang, S. F., Liaw, J. & Hung, P. H., Nov 1 2009, In : Human Gene Therapy. 20, 11, p. 1344-1350 7 p.

Research output: Contribution to journalArticle

Hypoparathyroidism
Parathyroid Hormone
Genetic Therapy
Complementary DNA
Edetic Acid
37 Citations (Scopus)

PTEN promoter methylation and LOH of 10q22-23 locus in PTEN expression of ovarian clear cell adenocarcinomas

Ho, C. M., Lin, M. C., Huang, S. H., Huang, C. J., Lai, H. C., Chien, T. Y. & Chang, S. F., Feb 2009, In : Gynecologic Oncology. 112, 2, p. 307-313 7 p.

Research output: Contribution to journalArticle

Clear Cell Adenocarcinoma
Loss of Heterozygosity
Phosphoric Monoester Hydrolases
Methylation
Tensins
14 Citations (Scopus)
trichostatin A
Nitric Oxide Synthase Type II
Lipopolysaccharides
Macrophages
Carrier Proteins
2010
15 Citations (Scopus)

Chymase mediates paraquat-induced collagen production in human lung fibroblasts

Lang, Y. D., Chang, S. F., Wang, L-F. & Chen, C. M., Mar 1 2010, In : Toxicology Letters. 193, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

Chymases
Paraquat
Fibroblasts
Collagen
Lung
18 Citations (Scopus)

Polymeric micelle gene delivery of bcl-xL via eye drop reduced corneal apoptosis following epithelial debridement

Tong, Y. C., Chang, S. F., Kao, W. W. Y., Liu, C. Y. & Liaw, J., Oct 2010, In : Journal of Controlled Release. 147, 1, p. 76-83 8 p.

Research output: Contribution to journalArticle

Ophthalmic Solutions
Micelles
Debridement
DNA Fragmentation
Apoptosis
16 Citations (Scopus)

Promoter methylation of sFRP5 in patients with ovarian clear cell adenocarcinomaARTICLE

Ho, C. M., Lai, H. C., Huang, S. H., Chien, T. Y., Lin, M. C. & Chang, S. F., Apr 2010, In : European Journal of Clinical Investigation. 40, 4, p. 310-318 9 p.

Research output: Contribution to journalArticle

Clear Cell Adenocarcinoma
Methylation
Genes
Tumor Suppressor Protein p14ARF
Cells
22 Citations (Scopus)

Type-specific human papillomavirus oncogene messenger RNA levels correlate with the severity of cervical neoplasia

Ho, C. M., Lee, B. H., Chang, S. F., Chien, T. Y., Huang, S. H., Yan, C. C. & Cheng, W. F., Aug 1 2010, In : International Journal of Cancer. 127, 3, p. 622-632 11 p.

Research output: Contribution to journalArticle

Oncogenes
Human papillomavirus 6
Messenger RNA
DNA
Real-Time Polymerase Chain Reaction
2011
5 Citations (Scopus)

Analysis of the CYP21A2 gene with intergenic recombination and multiple gene deletions in the RCCX module

Chang, S. F. & Lee, H. H., Jan 1 2011, In : Genetic Testing and Molecular Biomarkers. 15, 1-2, p. 35-42 8 p.

Research output: Contribution to journalArticle

Gene Deletion
Genetic Recombination
Southern Blotting
Mutation
Genes
21 Citations (Scopus)

Arctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes

Tsai, W. J., Chang, C. T., Wang, G. J., Li, Z-H., Chang, S. F., Lu, S. C. & Kuo, Y. C., Mar 25 2011, In : Chinese Medicine. 6, 12.

Research output: Contribution to journalArticle

Arctium
Interferons
Interleukin-2
T-Lymphocytes
Gene Expression
3 Citations (Scopus)

Clinical significance of signal pattern of high-risk human papillomavirus using a novel fluorescence in situ hybridization assay in cervical cytology

Ho, C. M., Lee, B. H., Chang, S. F., Chien, T. Y., Huang, S. H., Yan, C. C. & Cheng, W. F., Mar 2011, In : Clinical Microbiology and Infection. 17, 3, p. 386-394 9 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Cell Biology
Cervical Intraepithelial Neoplasia
Polymerase Chain Reaction
Human papillomavirus 18