ShuMei Chen

Visiting staff

Taipei Municipal Wanfang Hospital

Email99318@w.tmu.edu.tw

112 Citations
6 h-Index

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Personal profile

Education

2001 Taipei Medical University

Experience

2001-2010 Chang Gung Memorial Hospital
2010- Wangfang Hospital

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Inhibitor of Apoptosis Proteins Medicine & Life Sciences

Medulloblastoma Medicine & Life Sciences

zoledronic acid Medicine & Life Sciences

Glioblastoma Medicine & Life Sciences

Neoplasm Transplantation Medicine & Life Sciences

Drug Dose Response Relationship Medicine & Life Sciences

Neoplasm Invasiveness Medicine & Life Sciences

Lung Neoplasms Medicine & Life Sciences

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Research Output 2012 2018

112 Citations
6 h-Index
11 Article
1 Review article

Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21

Chen, S. M., Lin, T. K., Tseng, Y. Y., Tu, C. H., Lui, T. N., Huang, S. F., Hsieh, L. L. & Li, Y. Y., Jan 1 2018, (Accepted/In press) In : Cancer Medicine.

Research output: Contribution to journal › Article

Inhibitor of Apoptosis Proteins

Medulloblastoma

G2 Phase

Cell Division

Cell Proliferation

7 Citations (Scopus)

Autophagic mechanism in anti-cancer immunity: Its pros and cons for cancer therapy

Li, Y. Y., Feun, L. G., Thongkum, A., Tu, C. H., Chen, S. M., Wangpaichitr, M., Wu, C., Kuo, M. T. & Savaraj, N., Jun 19 2017, In : International Journal of Molecular Sciences. 18, 6, 1297.

Research output: Contribution to journal › Review article

Open Access

1 Citation (Scopus)

Degradation of AMPK-α1 sensitizes BRAF inhibitor-resistant melanoma cells to arginine deprivation

Li, Y. Y., Wu, C., Shah, S. S., Chen, S. M., Wangpaichitr, M., Kuo, M. T., Feun, L. G., Han, X., Suarez, M., Prince, J. & Savaraj, N., Dec 1 2017, In : Molecular Oncology. 11, 12, p. 1806-1825 20 p.

Research output: Contribution to journal › Article

Open Access

AMP-Activated Protein Kinases

Ubiquitin-Protein Ligases

Autophagy

Arginine

Melanoma

13 Citations (Scopus)

Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer

Wangpaichitr, M., Wu, C., Li, Y. Y., Nguyen, D. J. M., Kandemir, H., Shah, S., Chen, S., Feun, L. G., Prince, J. S., Kuo, M. T. & Savaraj, N., Jan 1 2017, In : Oncotarget. 8, 30, p. 49275-49292 18 p.

Research output: Contribution to journal › Article

Riluzole

Cisplatin

Reactive Oxygen Species

Lung Neoplasms

Glutamine

9 Citations (Scopus)

Blockade of inhibitors of apoptosis proteins in combination with conventional chemotherapy leads to synergistic antitumor activity in medulloblastoma and cancer stem-like cells

Chen, S. M., Li, Y. Y., Tu, C. H., Salazar, N., Tseng, Y. Y., Huang, S. F., Hsieh, L. L. & Lui, T. N., Aug 1 2016, In : PLoS One. 11, 8, e0161299.

Research output: Contribution to journal › Article

Inhibitor of Apoptosis Proteins

Medulloblastoma

Chemotherapy

Neoplastic Stem Cells

drug therapy