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Research Output 2000 2019

  • 2383 Citations
  • 23 h-Index
  • 100 Article
  • 1 Book
  • 1 Chapter
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Article
2019

A high linoleic acid diet exacerbates metabolic responses and gut microbiota dysbiosis in obese rats with diabetes mellitus

Lee, H. C., Yu, S. C., Lo, Y. C., Lin, I. H., Tung, T. H. & Huang, S. Y., Feb 1 2019, In : Food and Function. 10, 2, p. 786-798 13 p.

Research output: Contribution to journalArticle

Dysbiosis
Linoleic Acid
diabetes mellitus
intestinal microorganisms
linoleic acid
2 Citations (Scopus)

Causal relationships between adiposity and childhood asthma: bi-directional Mendelian Randomization analysis

Chen, Y. C., Fan, H. Y., Huang, Y. T., Huang, S. Y., Liou, T. H. & Lee, Y. L., Jan 1 2019, In : International Journal of Obesity. 43, 1, p. 73-81

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Adiposity
Asthma
Body Mass Index
Single Nucleotide Polymorphism

Clinical association between the metabolite of healthy gut microbiota, 3-indolepropionic acid and chronic kidney disease

Sun, C. Y., Lin, C. J., Pan, H. C., Lee, C. C., Lu, S. C., Hsieh, Y. T., Huang, S. Y. & Huang, H. Y., 2019, In : Clinical Nutrition.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Indican
Kidney
Healthy Volunteers
Metabolome
Caloric Restriction
Blood Proteins
Proteins
Complement C4b-Binding Protein
alpha-Macroglobulins
Reducing Diet
Haptoglobins
Phenotype
Waist Circumference
Abdominal Obesity

Lactobacillus paracasei PS23 decelerated age-related muscle loss by ensuring mitochondrial function in SAMP8 mice

Chen, L. H., Huang, S. Y., Huang, K. C., Hsu, C. C., Yang, K. C., Li, L. A., Chan, C. H. & Huang, H. Y., Jan 1 2019, In : Aging. 11, 2, p. 756-770 15 p.

Research output: Contribution to journalArticle

Sarcopenia
Muscles
Reactive Oxygen Species
Muscle Strength
Control Groups

Melatonergic agonist regulates circadian clock genes and peripheral inflammatory and neuroplasticity markers in patients with depression and anxiety

Kumaran Satyanarayanan, S., Chien, Y-C., Pei-Chen Chang, J., Huang, S-Y., Guu, T-W., Su, H. & Su, K-P., Mar 6 2019, In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

Circadian Clocks
Neuronal Plasticity
Anxiety
Depression
Genes
2018
1 Citation (Scopus)
Reducing Diet
Fish Oils
fish oils
interleukin-6
Weight Loss
5 Citations (Scopus)

Anti-Oxidative Effects of Melatonin Receptor Agonist and Omega-3 Polyunsaturated Fatty Acids in Neuronal SH-SY5Y Cells: Deciphering Synergic Effects on Anti-Depressant Mechanisms

Satyanarayanan, S. K., Shih, Y. H., Chien, Y. C., Huang, S. Y., Gałecki, P., Kasper, S., Chang, J. P. C. & Su, K. P., Feb 3 2018, (Accepted/In press) In : Molecular Neurobiology. p. 1-14 14 p.

Research output: Contribution to journalArticle

Melatonin Receptors
Omega-3 Fatty Acids
Unsaturated Fatty Acids
Eicosapentaenoic Acid
Fluoxetine
3 Citations (Scopus)

Effects of calorie restriction plus fish oil supplementation on abnormal metabolic characteristics and the iron status of middle-aged obese women

Utami, F. A., Lee, H. C., Su, C. T., Guo, Y. R., Tung, Y. T. & Huang, S. Y., Feb 1 2018, In : Food and Function. 9, 2, p. 1152-1162 11 p.

Research output: Contribution to journalArticle

middle-aged adults
Fish Oils
metabolic syndrome
fish oils
Iron
Methadone
Genetic Polymorphisms
Polymorphism
Fatty Acids
Fatty Acid Desaturases

Inhibitory effect of PDGF-BB and serum-stimulated responses in vascular smooth muscle cell proliferation by hinokitiol via up-regulation of p21 and p53

Li, J-Y., Liu, C-P., Shiao, W-C., Jayakumar, T., Li, Y-S., Chang, N-C., Huang, S-Y. & Hsieh, C-Y., Jan 1 2018, In : Archives of Medical Science. 14, 3, p. 579-587 9 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Up-Regulation
Cell Proliferation
Serum
3 Citations (Scopus)

Lactobacillus paracasei PS23 delays progression of age-related cognitive decline in senescence accelerated mouse prone 8 (SAMP8) mice

Huang, S. Y., Chen, L. H., Wang, M. F., Hsu, C. C., Chan, C. H., Li, J. X. & Huang, H. Y., Jul 12 2018, In : Nutrients. 10, 7, 894.

Research output: Contribution to journalArticle

Lactobacillus paracasei
mice
monoamines
Probiotics
probiotics
1 Citation (Scopus)
Omega-3 Fatty Acids
Cricetinae
9,10-Dimethyl-1,2-benzanthracene
Tumor Burden
Carcinoma
2 Citations (Scopus)

n-3 polyunsaturated fatty acids prevent d-galactose-induced cognitive deficits in prediabetic rats

Guo, Y. R., Lee, H. C., Lo, Y. C., Yu, S. C. & Huang, S. Y., Apr 25 2018, In : Food & function. 9, 4, p. 2228-2239 12 p.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Fish Oils
Galactose
galactose
omega-3 fatty acids
11 Citations (Scopus)

Polyunsaturated fatty acids and inflammatory markers in major depressive episodes during pregnancy

Chang, J. P. C., Lin, C. Y., Lin, P. Y., Shih, Y. H., Chiu, T. H., Ho, M., Yang, H. T., Huang, S. Y., Gałecki, P. & Su, K. P., Jan 3 2018, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 80, p. 273-278

Research output: Contribution to journalArticle

Unsaturated Fatty Acids
Omega-3 Fatty Acids
Depression
Pregnancy
Docosahexaenoic Acids
2017

Fatty acid components in Asian female patients with irritable bowel syndrome

Chua, C. S., Huang, S. Y., Cheng, C. W., Bai, C. H., Hsu, C. Y., Chiu, H. W. & Hsu, J. L., Dec 1 2017, In : Medicine (United States). 96, 49, e9094.

Research output: Contribution to journalArticle

Irritable Bowel Syndrome
Fatty Acids
Essential Fatty Acids
Abdominal Pain
Monounsaturated Fatty Acids

Methionine synthase 2756AA polymorphism is associated with the risk of cognitive impairment in patients with late-life depression

Yang, Y. H., Chiu, C. C., Teng, H. W., Chu, C. P., Chang, C. J., Chiu, W. C., Chen, C. H., Lu, M. L., Liu, S. I., Huang, S. Y., Liu, H. C. & Sun, I. W., Mar 1 2017, In : Asia-Pacific Psychiatry. 9, 1

Research output: Contribution to journalArticle

5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Apolipoprotein E4
Alleles
Depression
Genotype
13 Citations (Scopus)

Reproducibility and Repeatability of Computer Tomography-based Measurement of Abdominal Subcutaneous and Visceral Adipose Tissues

Lee, Y. H., Hsiao, H. F., Yang, H. T., Huang, S. Y. & Chan, W. P., Jan 10 2017, In : Scientific Reports. 7, 40389.

Research output: Contribution to journalArticle

tomography
reproducibility
repeatability
adipose tissue
X-radiation
7 Citations (Scopus)

Transcription factor HBP1 is a direct anti-cancer target of transcription factor FOXO1 in invasive oral cancer

Chan, C. Y., Huang, S. Y., Sheu, J. J. C., Roth, M. M., Chou, I. T., Lien, C. H., Lee, M. F. & Huang, C. Y., 2017, In : Oncotarget. 8, 9, p. 14537-14548 12 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Transcription Factors
Binding Sites
Neoplasms
Phosphatidylinositol 3-Kinases

β-Glucan, but not Lactobacillus plantarum P-8, inhibits lipid accumulation through selected lipid metabolic enzymes in obese rats

Lee, H. C., Yu, W. T., Guo, Y. R. & Huang, S-Y., Feb 1 2017, In : Journal of Food Biochemistry. 41, 1, e12336.

Research output: Contribution to journalArticle

Lactobacillus plantarum
Glucans
glucans
White Adipose Tissue
white adipose tissue
2016
middle-aged adults
Fish Oils
fish oils
insulin resistance
Insulin Resistance
15 Citations (Scopus)

Prevention of arterial thrombosis by nobiletin: In vitro and in vivo studies

Lu, W-J., Lin, K. C., Liu, C. P., Lin, C. Y., Wu, H. C., Chou, D. S., Geraldine, P., Huang, S. Y., Hsieh, C. Y. & Sheu, J. R., Feb 1 2016, In : Journal of Nutritional Biochemistry. 28, p. 1-8 8 p.

Research output: Contribution to journalArticle

Platelets
Thrombosis
Platelet Aggregation
Platelet Activation
Blood Platelets
1 Citation (Scopus)

The efficacy of blueberry and grape seed extract combination on triple therapy for Helicobacter pylori eradication: A randomised controlled trial

Chua, C. S., Yang, K-C., Chen, J. H., Liu, Y. H., Hsu, Y. H., Lee, H. C. & Huang, S-Y., Jan 1 2016, In : International Journal of Food Sciences and Nutrition. 67, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

Grape Seed Extract
Blueberry Plants
grape seed extract
Helicobacter pylori
blueberries
2015
16 Citations (Scopus)
Fish Oils
Powders
Diet
Proteins
Meals
9 Citations (Scopus)

Effects of calorie restriction with n-3 long-chain polyunsaturated fatty acids on metabolic syndrome severity in obese subjects: A randomize-controlled trial

Lee, H. C., Cheng, W. Y., Hsu, Y. H., Su, H. Y., Huang, B. E. T. G., Lin, Y-K., Chan, W. P., Su, C-T. & Huang, S-Y., 2015, In : Journal of Functional Foods. 19, p. 929-940 12 p.

Research output: Contribution to journalArticle

long chain polyunsaturated fatty acids
Fish Oils
metabolic syndrome
Unsaturated Fatty Acids
fish oils
3 Citations (Scopus)

N-3 Polyunsaturated fatty acids ameliorate cognitive age-related impairments and depressive behaviour in unchallenged aged prediabetic rats

Guo, Y. R., Hsu, Y. H., Liang, A., Lu, W. J., Wu, C. H., Lee, H. C. & Huang, S. Y., Dec 1 2015, In : Journal of Functional Foods. 19, p. 522-536 15 p., 1300.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
omega-3 fatty acids
polyunsaturated fatty acids
rats
Oils
11 Citations (Scopus)

Serum ferritin levels and polycystic ovary syndrome in obese and nonobese women

Ko, P. C., Huang, S. Y., Hsieh, C. H., Hsu, M. I. & Hsu, C-S., Aug 1 2015, In : Taiwanese Journal of Obstetrics and Gynecology. 54, 4, p. 403-407 5 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Ferritins
Serum
Insulin Resistance
Hypertriglyceridemia
5 Citations (Scopus)

Xanthohumol from Humulus lupulus L. induces glioma cell autophagy via inhibiting Akt/mTOR/S6K pathway

Lu, W-J., Chang, C. C., Lien, L. M., Yen, T. L., Chiu, H. C., Huang, S. Y., Sheu, J. R. & Lin, K. H., Oct 1 2015, In : Journal of Functional Foods. 18, p. 538-549 12 p., 1255.

Research output: Contribution to journalArticle

Humulus lupulus
Humulus
autophagy
Autophagy
Glioma
2014
12 Citations (Scopus)

Antidepressant-like effects of Perilla frutescens seed oil during a forced swimming test

Lee, H. C., Ko, H. K., Huang, B. E. T. G., Chu, Y. H. & Huang, S. Y., 2014, In : Food and Function. 5, 5, p. 990-996 7 p.

Research output: Contribution to journalArticle

Perilla frutescens
antidepressants
seed oils
Antidepressive Agents
Brain-Derived Neurotrophic Factor
8 Citations (Scopus)

Anti-inflammatory and hypoglycemic efficacy of Poria cocos and Dioscorea opposita in prediabetes mellitus rats

Lee, H. C., Cheng, W. Y., Huang, B. E. T. G., Hsu, Y. H. & Huang, S. Y., 2014, In : RSC Advances. 4, 98, p. 55649-55657 9 p.

Research output: Contribution to journalArticle

Hypoglycemic Agents
Rats
Anti-Inflammatory Agents
Polyunsaturated fatty acids
Blood
10 Citations (Scopus)
Aminobutyrates
gamma-Aminobutyric Acid
Glycoproteins
Collagen
Blood Platelets
4 Citations (Scopus)

Clinical and biochemical characteristics of women with menstrual disturbance

Shen, S. Y., Huang, S. Y., Hsieh, C. H., Hsu, M. I., Cheng, C. Y. & Hsu, C-S., 2014, In : Taiwanese Journal of Obstetrics and Gynecology. 53, 2, p. 178-182 5 p.

Research output: Contribution to journalArticle

Prolactin
Amenorrhea
Oligomenorrhea
Insulin Resistance
Androgens
14 Citations (Scopus)

Multidrug resistance protein 4 (MRP4/ABCC4) regulates thrombus formation in vitro and in vivo

Lien, L. M., Chen, Z. C., Chung, C. L., Yen, T. L., Chiu, H. C., Chou, D. S., Huang, S. Y., Sheu, J. R., Lu, W-J. & Lin, K. H., Aug 15 2014, In : European Journal of Pharmacology. 737, p. 159-167 9 p.

Research output: Contribution to journalArticle

P-Glycoproteins
Thrombosis
Cyclic Nucleotides
Platelet Activation
Collagen
21 Citations (Scopus)

Role of a Janus kinase 2-dependent signaling pathway in platelet activation

Lu, W-J., Lin, K. C., Huang, S. Y., Thomas, P. A., Wu, Y. H., Wu, H. C., Lin, K. H. & Sheu, J. R., 2014, In : Thrombosis Research. 133, 6, p. 1088-1096 9 p.

Research output: Contribution to journalArticle

Janus Kinase 2
Platelet Activation
Collagen
Janus Kinases
Protein Kinase C
2013
26 Citations (Scopus)

Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo

Lin, K. H., Kuo, J. R., Lu, W-J., Chung, C. L., Chou, D. S., Huang, S. Y., Lee, H. C. & Sheu, J. R., May 15 2013, In : Biochemical Pharmacology. 85, 10, p. 1478-1485 8 p.

Research output: Contribution to journalArticle

Platelet Activation
Platelets
Thrombosis
Chemical activation
Platelet Aggregation
5 Citations (Scopus)
Hyperhomocysteinemia
Homocysteine
Polycystic Ovary Syndrome
Insulin Resistance
Hyperandrogenism
12 Citations (Scopus)
Fish Oils
Probiotics
Vegetables
Fruit
Asthma
2012
48 Citations (Scopus)

A meta-analytic review of polyunsaturated fatty acid compositions in dementia

Lin, P. Y., Chiu, C. C., Huang, S. Y. & Su, K. P., 2012, In : Journal of Clinical Psychiatry. 73, 9, p. 1245-1254 10 p.

Research output: Contribution to journalArticle

Eicosapentaenoic Acid
Unsaturated Fatty Acids
Docosahexaenoic Acids
Dementia
Omega-3 Fatty Acids
22 Citations (Scopus)

Associations between n-3 PUFA concentrations and cognitive function after recovery from late-life depression

Chiu, C. C., Frangou, S., Chang, C. J., Chiu, W. C., Liu, H. C., Sun, I. W., Liu, S. I., Lu, M. L., Chen, C. H., Huang, S. Y., Dewey, M. E. & Stewart, R., Feb 1 2012, In : American Journal of Clinical Nutrition. 95, 2, p. 420-427 8 p.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Cognition
Depression
Erythrocyte Membrane
alpha-Linolenic Acid
17 Citations (Scopus)

Associations of polyunsaturated fatty acids with residual depression or anxiety in older people with major depression

Jadoon, A., Chiu, C. C., McDermott, L., Cunningham, P., Frangou, S., Chang, C. J., Sun, I. W., Liu, S. I., Lu, M. L., Su, K. P., Huang, S. Y. & Stewart, R., Feb 2012, In : Journal of Affective Disorders. 136, 3, p. 918-925 8 p.

Research output: Contribution to journalArticle

Unsaturated Fatty Acids
Anxiety
Depression
Omega-3 Fatty Acids
Linoleic Acid
27 Citations (Scopus)

Early enteral nutrition and clinical outcomes of severe traumatic brain injury patients in acute stage: A multi-center cohort study

Chiang, Y-H., Chao, D. P., Chu, S. F., Lin, H. W., Huang, S-Y., Yeh, Y. S., Lui, T-N., Binns, C. W. & Chiu, W-T., Jan 1 2012, In : Journal of Neurotrauma. 29, 1, p. 75-80 6 p.

Research output: Contribution to journalArticle

Glasgow Coma Scale
Enteral Nutrition
Cohort Studies
Wounds and Injuries
Traumatic Brain Injury
18 Citations (Scopus)

Fractional carbon dioxide laser treatment to enhance skin permeation of ascorbic acid 2-glucoside with minimal skin disruption

Hsiao, C. Y., Huang, C. H., Hu, S., Ko, Y. S., Sung, H. C., Chen, C. C. & Huang, S. Y., Aug 2012, In : Dermatologic Surgery. 38, 8, p. 1284-1293 10 p.

Research output: Contribution to journalArticle

Gas Lasers
Lasers
Skin
Carbon Monoxide
Therapeutics
13 Citations (Scopus)

Transculturalization of a diabetes-specific nutrition algorithm: Asian application

Su, H. Y., Tsang, M. W., Huang, S-Y., Mechanick, J. I., Sheu, W. H. H. & Marchetti, A., Apr 2012, In : Current Diabetes Reports. 12, 2, p. 213-219 7 p.

Research output: Contribution to journalArticle

Nutrition Therapy
Practice Guidelines
Advisory Committees
Delivery of Health Care
Type 2 Diabetes Mellitus
2011
10 Citations (Scopus)

A novel role for tamoxifen in the inhibition of human platelets

Chang, Y., Lee, J. J., Chen, W. F., Chou, D. S., Huang, S. Y. & Sheu, J. R., Feb 2011, In : Translational Research. 157, 2, p. 81-91 11 p.

Research output: Contribution to journalArticle

Tamoxifen
Platelets
Blood Platelets
Platelet Activation
Chemical activation
27 Citations (Scopus)

A novel role of sesamol in inhibiting NF-B-mediated signaling in platelet activation

Chang, C. C., Lu, W-J., Ong, E. T., Chiang, C-W., Lin, S-C., Huang, S. Y. & Sheu, J. R., 2011, In : Journal of Biomedical Science. 18, 1, 93.

Research output: Contribution to journalArticle

Platelet Activation
Platelets
Chemical activation
Platelet Aggregation
Phosphorylation
21 Citations (Scopus)

Skin pretreatment with lasers promotes the transdermal delivery of vitamin C derivatives

Hsiao, C. Y., Huang, C. H., Hu, S., Ko, Y. S., Sung, H. C. & Huang, S. Y., May 2011, In : Lasers in Medical Science. 26, 3, p. 369-376 8 p.

Research output: Contribution to journalArticle

Ascorbic Acid
Lasers
Skin
Solid-State Lasers
Carbon Monoxide
2010
14 Citations (Scopus)

A common variant in the adiponectin gene on weight loss and body composition under sibutramine therapy in obesity

Hsiao, T. J., Wu, L. S. H., Huang, S. Y. & Lin, E., 2010, In : Clinical Pharmacology: Advances and Applications. 2, 1, p. 105-110 6 p.

Research output: Contribution to journalArticle

sibutramine
Adiponectin
Body Composition
Weight Loss
Obesity
257 Citations (Scopus)

A meta-analytic review of polyunsaturated fatty acid compositions in patients with depression

Lin, P. Y., Huang, S. Y. & Su, K. P., Jul 15 2010, In : Biological Psychiatry. 68, 2, p. 140-147 8 p.

Research output: Contribution to journalArticle

Unsaturated Fatty Acids
Omega-3 Fatty Acids
Depression
Eicosapentaenoic Acid
Docosahexaenoic Acids
Polycystic Ovary Syndrome
Apnea
Sleep
Heart Rate
C-Reactive Protein