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Research Output

  • 835 Citations
  • 18 h-Index
  • 50 Article
  • 4 Review article
  • 1 Erratum
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Article
2020

Dietary compound isoliquiritigenin, an antioxidant from licorice, suppresses triple-negative breast tumor growth via apoptotic death program activation in cell and xenograft animal models

Lin, P. H., Chiang, Y. F., Shieh, T. M., Chen, H. Y., Shih, C. K., Wang, T. H., Wang, K. L., Huang, T. C., Hong, Y. H., Li, S. C. & Hsia, S. M., Mar 10 2020, In : Antioxidants. 9, 3, 228.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Disturbed Gastrointestinal Contractility in a Polycystic Ovary Syndrome Rat Model

Wang, K. L., Hsia, S. M., Wang, P. S. & Lin, P. H., Jan 1 2020, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Downregulation of testosterone production through luteinizing hormone receptor regulation in male rats exposed to 17α-ethynylestradiol

Lin, P. H., Kuo, T. H., Chen, C. C., Jian, C. Y., Chen, C. W., Wang, K. L., Kuo, Y. C., Shen, H. Y., Hsia, S. M., Wang, P. S., Lieu, F. K. & Wang, S. W., Jan 31 2020, In : Scientific Reports. 10, 1, p. 1576 1576.

Research output: Contribution to journalArticle

Open Access

Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation

Lin, P. H., Tung, Y. T., Chen, H. Y., Chiang, Y. F., Hong, H. C., Huang, K. C., Hsu, S. P., Huang, T. C. & Hsia, S. M., Jan 1 2020, In : Journal of Pineal Research. 68, 1, p. e12620 e12620.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Synbiotic combination of djulis (Chenopodium formosanum) and lactobacillus acidophilus inhibits colon carcinogenesis in rats

Lee, C. W., Chen, H. J., Chien, Y. H., Hsia, S. M., Chen, J. H. & Shih, C. K., Jan 2020, In : Nutrients. 12, 1, 103.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

The effects of isoliquiritigenin on endometriosis in vivo and in vitro study

Hsu, Y. W., Chen, H. Y., Chiang, Y. F., Chang, L. C., Lin, P. H. & Hsia, S. M., Oct 2020, In : Phytomedicine. 77, 153214.

Research output: Contribution to journalArticle

2019
Open Access
3 Citations (Scopus)

Arecoline-regulated ataxia telangiectasia mutated expression level in oral cancer progression

Tu, H. F., Chen, M. Y., Lai, J. C. Y., Chen, Y. L., Wong, Y. W., Yang, C. C., Chen, H. Y., Hsia, S. M., Shih, Y. H. & Shieh, T. M., Aug 2019, In : Head and Neck. 41, 8, p. 2525-2537 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Dietary antioxidant trans-cinnamaldehyde reduced visfatin-induced breast cancer progression: In vivo and in vitro study

Chiang, Y. F., Chen, H. Y., Huang, K. C., Lin, P. H. & Hsia, S. M., Dec 2019, In : Antioxidants. 8, 12, 625.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Dietary glycotoxins, advanced glycation end products, inhibit cell proliferation and progesterone secretion in ovarian granulosa cells and mimic PCOS-like symptoms

Lin, P. H., Chang, C. C., Wu, K. H., Shih, C. K., Chiang, W., Chen, H. Y., Shih, Y. H., Wang, K. L., Hong, Y. H., Shieh, T. M. & Hsia, S. M., Aug 1 2019, In : Biomolecules. 9, 8, 327.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Effects of mineral trioxide aggregate and bioceramics on macrophage differentiation and polarization in vitro

Tu, M. G., Sun, K. T., Wang, T. H., He, Y. Z., Hsia, S. M., Tsai, B. H., Shih, Y. H. & Shieh, T. M., Jan 1 2019, In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Isoliquiritigenin suppresses E2-induced uterine leiomyoma growth through the modulation of cell death program and the repression of ECM accumulation

Lin, P. H., Kung, H. L., Chen, H. Y., Huang, K. C. & Hsia, S. M., Aug 1 2019, In : Cancers. 11, 8, 1131.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo

Chen, H-Y., Lin, P-H., Shih, Y-H., Wang, K-L., Hong, Y-H., Shieh, T-M., Huang, T-C. & Hsia, S-M., Apr 1 2019, In : Antioxidants. 8, 4, 99.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Preventive effects of fucoidan and fucoxanthin on hyperuricemic rats induced by potassium oxonate

Chau, Y. T., Chen, H. Y., Lin, P. H. & Hsia, S. M., Jun 10 2019, In : Marine Drugs. 17, 6, 343.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Salivary LDOC1 is a gender-difference biomarker of oral squamous cell carcinoma

Liu, C-J., Chen, J-H., Hsia, S-M., Liao, C-C., Chang, H-W., Shieh, T-M. & Shih, Y-H., Jan 1 2019, In : PeerJ. 2019, 4, p. e6732 e6732.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Slug mediates myofibroblastic differentiation to promote fibrogenesis in buccal mucosa

Fang, C. Y., Hsia, S. M., Hsieh, P. L., Liao, Y. W., Peng, C. Y., Wu, C. Z., Lin, K. C., Tsai, L. L. & Yu, C. C., May 2019, In : Journal of Cellular Physiology. 234, 5, p. 6721-6730 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2018

Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression

Chen, H. Y., Huang, T. C., Lin, L. C., Shieh, T. M., Wu, C. H., Wang, K. L., Hong, Y. H. & Hsia, S. M., Oct 1 2018, In : Cellular Physiology and Biochemistry. 49, 5, p. 1970-1986 17 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
3 Citations (Scopus)

Manzamine a exerts anticancer activity against human colorectal cancer cells

Lin, L. C., Kuo, T. T., Chang, H. Y., Liu, W. S., Hsia, S. M. & Huang, T. C., Jul 29 2018, In : Marine Drugs. 16, 8, 252.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Protective Effect of Melatonin against Oxidative Stress-Induced Apoptosis and Enhanced Autophagy in Human Retinal Pigment Epithelium Cells

Chang, C. C., Huang, T. Y., Chen, H. Y., Huang, T. C., Lin, L. C., Chang, Y. J. & Hsia, S. M., Jan 1 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 9015765.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2017

Effects of Adlay Hull and Testa Ethanolic Extracts on the Growth of Uterine Leiomyoma Cells

Hsia, S-M., Lin, K-H., Chiang, W., Wu, C-H., Shieh, T-M., Huang, T-C., Chen, H-Y. & Lin, L-C., 2017, In : 調適醫學. 9, 2, p. 85-96 12 p.

Research output: Contribution to journalArticle

Insulin induction instigates cell proliferation and metastasis in human colorectal cancer cells

Lu, C. C., Chu, P. Y., Hsia, S. M., Wu, C. H., Tung, Y. T. & Yen, G. C., Feb 1 2017, In : International Journal of Oncology. 50, 2, p. 736-744 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Isoliquiritigenin induces autophagy and inhibits ovarian cancer cell growth

Chen, H. Y., Huang, T. C., Shieh, T. M., Wu, C. H., Lin, L. C. & Hsia, S. M., Oct 1 2017, In : International Journal of Molecular Sciences. 18, 10, 2025.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Melatonin suppresses hepatocellular carcinoma progression via lncRNA-CPS1-IT-mediated HIF-1α inactivation

Wang, T. H., Wu, C. H., Yeh, C. T., Su, S. C., Hsia, S. M., Liang, K. H., Chen, C. C., Hsueh, C. & Chen, C. Y., 2017, In : Oncotarget. 8, 47, p. 82280-82293 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The hepatoprotective effect of Phyllanthus emblica L. fruit on high fat diet-induced non-alcoholic fatty liver disease (NAFLD) in SD rats

Huang, C. Z., Tung, Y. T., Hsia, S. M., Wu, C. H. & Yen, G. C., Feb 1 2017, In : Food and Function. 8, 2, p. 842-850 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
10 Citations (Scopus)
2016

Capsaicin, an active ingredient from chilli peppers, attenuates glycative stress and restores sRAGE levels in diabetic rats

Hsia, S. M., Lee, W. H., Yen, G. C. & Wu, C. H., Mar 1 2016, In : Journal of Functional Foods. 21, p. 406-417 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Evaluation of the antibacterial potential of liquid and vapor phase phenolic essential oil compounds against oral microorganisms

Wang, T. H., Hsia, S-M., Wu, C-H., Ko, S. Y., Yuanchien Chen, M., Shih, Y. H., Shieh, T. M., Chuang, L. C. & Wu, Y. C., Sep 1 2016, In : PLoS One. 11, 9, e0163147.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Inhibitory effects of Phyllanthus emblica L. on hepatic steatosis and liver fibrosis in vitro

Lu, C. C., Yang, S. H., Hsia, S. M., Wu, C. H. & Yen, G. C., Jan 1 2016, In : Journal of Functional Foods. 20, p. 20-30 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma

Hsia, S. M., Yu, C. C., Shih, Y. H., Yuanchien Chen, M., Wang, T. H., Huang, Y. T. & Shieh, T. M., 2016, In : Head and Neck.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

Wu, C-H., Chen, H. Y., Wang, C-W., Shieh, T. M., Huang, T-C., Lin, L. C., Wang, K. L. & Hsia, S-M., 2016, In : Oncotarget. 7, 45, p. 73432-73447 16 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Resveratrol inhibits proliferation of myometrial and leiomyoma cells and decreases extracellular matrix-associated protein expression

Wu, C. H., Shieh, T. M., Wei, L. H., Cheng, T. F., Chen, H. Y., Huang, T. C., Wang, K. L. & Hsia, S. M., May 1 2016, In : Journal of Functional Foods. 23, p. 241-252 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015
9 Citations (Scopus)

Quercetin, a main flavonoid in onion, inhibits the PGF-induced uterine contraction in vitro and in vivo

Wu, C. H., Shieh, T. M., Wang, K. L., Huang, T. C. & Hsia, S. M., Dec 1 2015, In : Journal of Functional Foods. 19, p. 495-504 10 p., 1300.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

Application of the solvent extraction technique to investigation of the anti-inflammatory activity of adlay bran

Huang, D. W., Wu, C. H., Shih, C. K., Liu, C. Y., Shih, P. H., Shieh, T. M., Lin, C. I., Chiang, W. & Hsia, S. M., 2014, In : Food Chemistry. 145, p. 445-453 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Evaluation physical characteristics and comparison antimicrobial and anti-inflammation potentials of dental root canal sealers containing hinokitiol in vitro

Shih, Y. H., Lin, D. J., Chang, K. W., Hsia, S. M., Ko, S. Y., Lee, S. Y., Hsue, S. S., Wang, T. H., Chen, Y. L. & Shieh, T. M., Jun 10 2014, In : PLoS One. 9, 6, e94941.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Potential benefits of adlay on hyperandrogenism in human chorionic gonadotropin-treated theca cells and a rodent model of polycystic ovary syndrome

Wu, C. H., Chen, M. J., Shieh, T. M., Wang, K. L., Wu, Y. T., Hsia, S. M. & Chiang, W., 2014, In : Journal of Functional Foods. 11, C, p. 393-406 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2013

Anti-Proliferative Effects of Evodiamine on Human Breast Cancer Cells

Wang, K. L., Hsia, S. M., Yeh, J. Y., Cheng, S. C., Wang, P. S. & Wang, S. W., Jun 26 2013, In : PLoS One. 8, 6, e67297.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Inhibitory effects of isoliquiritigenin on the migration and invasion of human breast cancer cells

Wang, K. L., Hsia, S. M., Chan, C. J., Chang, F. Y., Huang, C. Y., Bau, D. T. & Wang, P. S., Apr 2013, In : Expert Opinion on Therapeutic Targets. 17, 4, p. 337-349 13 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

In vitro antimicrobial and anticancer potential of hinokitiol against oral pathogens and oral cancer cell lines

Shih, Y. H., Chang, K. W., Hsia, S. M., Yu, C. C., Fuh, L. J., Chi, T. Y. & Shieh, T. M., Jun 12 2013, In : Microbiological Research. 168, 5, p. 254-262 9 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma

Shih, Y. H., Chang, K. W., Chen, M. Y., Yu, C. C., Lin, D. J., Hsia, S. M., Huang, H. L. & Shieh, T. M., Feb 2013, In : Head and Neck. 35, 2, p. 250-256 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2011

Effects of polybrominated diphenyl ethers on steroidogenesis in rat Leydig cells

Wang, K. L., Hsia, S. M., Mao, I. F., Chen, M. L., Wang, S. W. & Wang, P. S., Aug 2011, In : Human Reproduction. 26, 8, p. 2209-2217 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Effects of resveratrol, a grape polyphenol, on uterine contraction and Ca2+ mobilization in rats in vivo and in vitro

Hsia, S. M., Wang, K. L. & Wang, P. S., May 2011, In : Endocrinology. 152, 5, p. 2090-2099 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Gastroprotective activities of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) on the growth of the stomach cancer ags cell line and indomethacin-induced gastric ulcers

Chung, C. P., Hsia, S. M., Lee, M. Y., Chen, H. J., Cheng, F., Chan, L. C., Kuo, Y. H., Lin, Y. L. & Chiang, W., Jun 8 2011, In : Journal of Agricultural and Food Chemistry. 59, 11, p. 6025-6033 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2010

Effects of Oral Nonylphenol on Testosterone Production in Rat Leydig Cells

Wu, J-J., Wang, K-L., Mao, I-F., Chen, M-L., Hsia, S-M. & Wang, P. S., 2010, In : 調適醫學. 2, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

2009

Effect of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) hull extracts on testosterone release from rat leydig cells

Hsia, S. M., Tseng, Y. W., Wang, S. W., Kuo, Y. H., Huang, D. W., Wang, P. S. & Chiang, W., May 2009, In : Phytotherapy Research. 23, 5, p. 687-695 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2008

Effects of adlay hull extracts on uterine contraction and Ca2+ mobilization in the rat

Hsia, S. M., Kuo, Y. H., Chiang, W. & Wang, P. S., Sep 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 3

Research output: Contribution to journalArticle

20 Citations (Scopus)
2007

Effects of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) hull extracts on the secretion of progesterone and estradiol in vivo and in vitro

Hsia, S. M., Yeh, C. L., Kuo, Y. H., Wang, P. S. & Chiang, W., Oct 2007, In : Experimental Biology and Medicine. 232, 9, p. 1181-1194 14 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2006

Downregulation of progesterone biosynthesis in rat granulosa cells by adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) bran extracts

Hsia, S. M., Chiang, W., Kuo, Y. H. & Wang, P. S., May 2006, In : International Journal of Impotence Research. 18, 3, p. 264-274 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells

Chang, L. L., Wun, A. W. S., Hung, C. T., Hsia, S. M., Chiang, W. & Wang, P. S., Nov 2006, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 374, 2, p. 141-152 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)