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Research Output 2006 2019

  • 657 Citations
  • 16 h-Index
  • 43 Article
  • 4 Review article
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Article
2019
2 Citations (Scopus)
Open Access
Coix
Stigmasterol
smooth muscle
hormones
Leiomyoma
1 Citation (Scopus)

Arecoline-regulated ataxia telangiectasia mutated expression level in oral cancer progression

Tu, H. F., Chen, M. Y., Lai, J. C. Y., Chen, Y. L., Wong, Y. W., Yang, C. C., Chen, H. Y., Hsia, S. M., Shih, Y. H. & Shieh, T. M., Jan 1 2019, In : Head and Neck.

Research output: Contribution to journalArticle

Arecoline
Ataxia Telangiectasia
Mouth Neoplasms
Squamous Cell Carcinoma
DNA Repair

Dietary glycotoxins, advanced glycation end products, inhibit cell proliferation and progesterone secretion in ovarian granulosa cells and mimic PCOS-like symptoms

Lin, P. H., Chang, C. C., Wu, K. H., Shih, C. K., Chiang, W., Chen, H. Y., Shih, Y. H., Wang, K. L., Hong, Y. H., Shieh, T. M. & Hsia, S. M., Aug 1 2019, In : Biomolecules. 9, 8, 327.

Research output: Contribution to journalArticle

Open Access
Advanced Glycosylation End Products
Granulosa Cells
Polycystic Ovary Syndrome
Cell proliferation
Progesterone
1 Citation (Scopus)

Effects of mineral trioxide aggregate and bioceramics on macrophage differentiation and polarization in vitro

Tu, M. G., Sun, K. T., Wang, T. H., He, Y. Z., Hsia, S. M., Tsai, B. H., Shih, Y. H. & Shieh, T. M., Jan 1 2019, In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Open Access
Pemetrexed
Macrophages
Autophagy
Cell Proliferation
Osteogenesis
1 Citation (Scopus)

Isoliquiritigenin suppresses E2-induced uterine leiomyoma growth through the modulation of cell death program and the repression of ECM accumulation

Lin, P. H., Kung, H. L., Chen, H. Y., Huang, K. C. & Hsia, S. M., Aug 1 2019, In : Cancers. 11, 8, 1131.

Research output: Contribution to journalArticle

Open Access
Leiomyoma
Extracellular Matrix
Cell Death
Myometrium
Growth
4 Citations (Scopus)

Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo

Chen, H-Y., Lin, P-H., Shih, Y-H., Wang, K-L., Hong, Y-H., Shieh, T-M., Huang, T-C. & Hsia, S-M., Apr 12 2019, In : Antioxidants. 8, 4

Research output: Contribution to journalArticle

Leiomyoma
Cell growth
Extracellular Matrix
Antioxidants
Growth

Preventive effects of fucoidan and fucoxanthin on hyperuricemic rats induced by potassium oxonate

Chau, Y. T., Chen, H. Y., Lin, P. H. & Hsia, S. M., Jun 10 2019, In : Marine Drugs. 17, 6, 343.

Research output: Contribution to journalArticle

Open Access
Hyperuricemia
Xanthine Oxidase
Uric Acid
Hypoxanthine
Control Groups

Salivary LDOC1 is a gender-difference biomarker of oral squamous cell carcinoma

Liu, C-J., Chen, J-H., Hsia, S-M., Liao, C-C., Chang, H-W., Shieh, T-M. & Shih, Y-H., 2019, In : PeerJ. 7, p. e6732

Research output: Contribution to journalArticle

squamous cell carcinoma
Biomarkers
gender differences
Squamous Cell Carcinoma
mouth
5 Citations (Scopus)

Slug mediates myofibroblastic differentiation to promote fibrogenesis in buccal mucosa

Fang, C. Y., Hsia, S. M., Hsieh, P. L., Liao, Y. W., Peng, C. Y., Wu, C. Z., Lin, K. C., Tsai, L. L. & Yu, C. C., 2019, In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Arecoline
Gastropoda
Mouth Mucosa
Collagen Type I
Myofibroblasts
2018
4 Citations (Scopus)

Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression

Chen, H. Y., Huang, T. C., Lin, L. C., Shieh, T. M., Wu, C. H., Wang, K. L., Hong, Y. H. & Hsia, S. M., Oct 1 2018, In : Cellular Physiology and Biochemistry. 49, 5, p. 1970-1986 17 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
Leiomyoma
Cell Proliferation
Heterografts
Neoplasms
2 Citations (Scopus)
Coix
Uterine Neoplasms
Hexanes
Sarcoma
Doxorubicin
5 Citations (Scopus)

Manzamine a exerts anticancer activity against human colorectal cancer cells

Lin, L. C., Kuo, T. T., Chang, H. Y., Liu, W. S., Hsia, S. M. & Huang, T. C., Jul 29 2018, In : Marine Drugs. 16, 8, 252.

Research output: Contribution to journalArticle

Human Activities
Colorectal Neoplasms
Porifera
HCT116 Cells
Carbolines
8 Citations (Scopus)

Protective Effect of Melatonin against Oxidative Stress-Induced Apoptosis and Enhanced Autophagy in Human Retinal Pigment Epithelium Cells

Chang, C. C., Huang, T. Y., Chen, H. Y., Huang, T. C., Lin, L. C., Chang, Y. J. & Hsia, S. M., Jan 1 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 9015765.

Research output: Contribution to journalArticle

Oxidative stress
Retinal Pigments
Retinal Pigment Epithelium
Autophagy
Melatonin
2017

Effects of Adlay Hull and Testa Ethanolic Extracts on the Growth of Uterine Leiomyoma Cells

Hsia, S-M., Lin, K-H., Chiang, W., Wu, C-H., Shieh, T-M., Huang, T-C., Chen, H-Y. & Lin, L-C., 2017, In : 調適醫學. 9, 2, p. 85-96 12 p.

Research output: Contribution to journalArticle

Leiomyoma
Growth
Quercetin
G2 Phase
Health
10 Citations (Scopus)

Insulin induction instigates cell proliferation and metastasis in human colorectal cancer cells

Lu, C. C., Chu, P. Y., Hsia, S. M., Wu, C. H., Tung, Y. T. & Yen, G. C., Feb 1 2017, In : International Journal of Oncology. 50, 2, p. 736-744 9 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Cell Proliferation
Insulin
Neoplasm Metastasis
HCT116 Cells
11 Citations (Scopus)

Isoliquiritigenin induces autophagy and inhibits ovarian cancer cell growth

Chen, H. Y., Huang, T. C., Shieh, T. M., Wu, C. H., Lin, L. C. & Hsia, S. M., Oct 1 2017, In : International Journal of Molecular Sciences. 18, 10, 2025.

Research output: Contribution to journalArticle

Autophagy
Cell growth
Ovarian Neoplasms
cancer
Fluorescence
11 Citations (Scopus)

Melatonin suppresses hepatocellular carcinoma progression via lncRNA-CPS1-IT-mediated HIF-1α inactivation

Wang, T. H., Wu, C. H., Yeh, C. T., Su, S. C., Hsia, S. M., Liang, K. H., Chen, C. C., Hsueh, C. & Chen, C. Y., 2017, In : Oncotarget. 8, 47, p. 82280-82293 14 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Melatonin
Hepatocellular Carcinoma
Epithelial-Mesenchymal Transition
Neoplasms
13 Citations (Scopus)

The hepatoprotective effect of Phyllanthus emblica L. fruit on high fat diet-induced non-alcoholic fatty liver disease (NAFLD) in SD rats

Huang, C. Z., Tung, Y. T., Hsia, S. M., Wu, C. H. & Yen, G. C., Feb 1 2017, In : Food and Function. 8, 2, p. 842-850 9 p.

Research output: Contribution to journalArticle

Phyllanthus emblica
hepatoprotective effect
fatty liver
High Fat Diet
high fat diet
8 Citations (Scopus)
Glycyrrhiza
licorice
doxorubicin
autophagy
Autophagy
2016
4 Citations (Scopus)

Capsaicin, an active ingredient from chilli peppers, attenuates glycative stress and restores sRAGE levels in diabetic rats

Hsia, S. M., Lee, W. H., Yen, G. C. & Wu, C. H., Mar 1 2016, In : Journal of Functional Foods. 21, p. 406-417 12 p.

Research output: Contribution to journalArticle

Capsicum
capsaicin
hot peppers
Capsaicin
active ingredients
13 Citations (Scopus)

Evaluation of the antibacterial potential of liquid and vapor phase phenolic essential oil compounds against oral microorganisms

Wang, T. H., Hsia, S-M., Wu, C-H., Ko, S. Y., Yuanchien Chen, M., Shih, Y. H., Shieh, T. M., Chuang, L. C. & Wu, Y. C., Sep 1 2016, In : PLoS One. 11, 9, e0163147.

Research output: Contribution to journalArticle

thymol
Thymol
Volatile Oils
vapors
Microorganisms
17 Citations (Scopus)

Inhibitory effects of Phyllanthus emblica L. on hepatic steatosis and liver fibrosis in vitro

Lu, C. C., Yang, S. H., Hsia, S. M., Wu, C. H. & Yen, G. C., Jan 1 2016, In : Journal of Functional Foods. 20, p. 20-30 11 p.

Research output: Contribution to journalArticle

Phyllanthus emblica
liver cirrhosis
fatty liver
Fatty Liver
Liver Cirrhosis
24 Citations (Scopus)

Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma

Hsia, S. M., Yu, C. C., Shih, Y. H., Yuanchien Chen, M., Wang, T. H., Huang, Y. T. & Shieh, T. M., 2016, In : Head and Neck.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
G2 Phase
Cell Division
DNA Damage
Squamous Cell Carcinoma
25 Citations (Scopus)

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

Wu, C-H., Chen, H. Y., Wang, C-W., Shieh, T. M., Huang, T-C., Lin, L. C., Wang, K. L. & Hsia, S-M., 2016, In : Oncotarget. 7, 45, p. 73432-73447 16 p.

Research output: Contribution to journalArticle

Autophagy
Endometrial Neoplasms
Apoptosis
Growth
Neoplasms
8 Citations (Scopus)

Resveratrol inhibits proliferation of myometrial and leiomyoma cells and decreases extracellular matrix-associated protein expression

Wu, C. H., Shieh, T. M., Wei, L. H., Cheng, T. F., Chen, H. Y., Huang, T. C., Wang, K. L. & Hsia, S. M., May 1 2016, In : Journal of Functional Foods. 23, p. 241-252 12 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
resveratrol
Leiomyoma
extracellular matrix
smooth muscle
2015
6 Citations (Scopus)
Long Noncoding RNA
Palmitic Acid
palmitic acid
stem cells
Stem Cells
2 Citations (Scopus)

Quercetin, a main flavonoid in onion, inhibits the PGF-induced uterine contraction in vitro and in vivo

Wu, C. H., Shieh, T. M., Wang, K. L., Huang, T. C. & Hsia, S. M., Dec 1 2015, In : Journal of Functional Foods. 19, p. 495-504 10 p., 1300.

Research output: Contribution to journalArticle

uterine contraction
Uterine Contraction
Dinoprost
Onions
Quercetin
2014
11 Citations (Scopus)

Application of the solvent extraction technique to investigation of the anti-inflammatory activity of adlay bran

Huang, D. W., Wu, C. H., Shih, C. K., Liu, C. Y., Shih, P. H., Shieh, T. M., Lin, C. I., Chiang, W. & Hsia, S. M., 2014, In : Food Chemistry. 145, p. 445-453 9 p.

Research output: Contribution to journalArticle

Coix lacryma-jobi
bran
Solvent extraction
anti-inflammatory activity
Anti-Inflammatory Agents
32 Citations (Scopus)

Evaluation physical characteristics and comparison antimicrobial and anti-inflammation potentials of dental root canal sealers containing hinokitiol in vitro

Shih, Y. H., Lin, D. J., Chang, K. W., Hsia, S. M., Ko, S. Y., Lee, S. Y., Hsue, S. S., Wang, T. H., Chen, Y. L. & Shieh, T. M., Jun 10 2014, In : PLoS One. 9, 6, e94941.

Research output: Contribution to journalArticle

Tooth Root
Dental Pulp Cavity
teeth
anti-infective agents
inflammation
4 Citations (Scopus)

Potential benefits of adlay on hyperandrogenism in human chorionic gonadotropin-treated theca cells and a rodent model of polycystic ovary syndrome

Wu, C. H., Chen, M. J., Shieh, T. M., Wang, K. L., Wu, Y. T., Hsia, S. M. & Chiang, W., 2014, In : Journal of Functional Foods. 11, C, p. 393-406 14 p.

Research output: Contribution to journalArticle

polycystic ovary syndrome
Coix lacryma-jobi
Theca Cells
Hyperandrogenism
androstenedione
2013
29 Citations (Scopus)

Anti-Proliferative Effects of Evodiamine on Human Breast Cancer Cells

Wang, K. L., Hsia, S. M., Yeh, J. Y., Cheng, S. C., Wang, P. S. & Wang, S. W., Jun 26 2013, In : PLoS One. 8, 6, e67297.

Research output: Contribution to journalArticle

breast neoplasms
Cells
Breast Neoplasms
estrogens
tamoxifen
49 Citations (Scopus)

Inhibitory effects of isoliquiritigenin on the migration and invasion of human breast cancer cells

Wang, K. L., Hsia, S. M., Chan, C. J., Chang, F. Y., Huang, C. Y., Bau, D. T. & Wang, P. S., Apr 2013, In : Expert Opinion on Therapeutic Targets. 17, 4, p. 337-349 13 p.

Research output: Contribution to journalArticle

Cells
Breast Neoplasms
Vascular Endothelial Growth Factor A
Assays
Matrix Metalloproteinases
36 Citations (Scopus)

In vitro antimicrobial and anticancer potential of hinokitiol against oral pathogens and oral cancer cell lines

Shih, Y. H., Chang, K. W., Hsia, S. M., Yu, C. C., Fuh, L. J., Chi, T. Y. & Shieh, T. M., Jun 12 2013, In : Microbiological Research. 168, 5, p. 254-262 9 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Cell Line
Aggregatibacter actinomycetemcomitans
Streptococcus mutans
Methicillin-Resistant Staphylococcus aureus
22 Citations (Scopus)

Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma

Shih, Y. H., Chang, K. W., Chen, M. Y., Yu, C. C., Lin, D. J., Hsia, S. M., Huang, H. L. & Shieh, T. M., Feb 2013, In : Head and Neck. 35, 2, p. 250-256 7 p.

Research output: Contribution to journalArticle

Protein-Lysine 6-Oxidase
Squamous Cell Carcinoma
Cell Proliferation
Neoplasms
Copper
2011
12 Citations (Scopus)

Effects of polybrominated diphenyl ethers on steroidogenesis in rat Leydig cells

Wang, K. L., Hsia, S. M., Mao, I. F., Chen, M. L., Wang, S. W. & Wang, P. S., Aug 2011, In : Human Reproduction. 26, 8, p. 2209-2217 9 p.

Research output: Contribution to journalArticle

Halogenated Diphenyl Ethers
Leydig Cells
Testosterone
Pregnenolone
Nuclear Proteins
20 Citations (Scopus)

Effects of resveratrol, a grape polyphenol, on uterine contraction and Ca2+ mobilization in rats in vivo and in vitro

Hsia, S. M., Wang, K. L. & Wang, P. S., May 2011, In : Endocrinology. 152, 5, p. 2090-2099 10 p.

Research output: Contribution to journalArticle

Uterine Contraction
Vitis
Polyphenols
Dinoprost
Myometrium
37 Citations (Scopus)

Gastroprotective activities of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) on the growth of the stomach cancer ags cell line and indomethacin-induced gastric ulcers

Chung, C. P., Hsia, S. M., Lee, M. Y., Chen, H. J., Cheng, F., Chan, L. C., Kuo, Y. H., Lin, Y. L. & Chiang, W., Jun 8 2011, In : Journal of Agricultural and Food Chemistry. 59, 11, p. 6025-6033 9 p.

Research output: Contribution to journalArticle

Coix
Coix lacryma-jobi
stomach ulcers
Endosperm
stomach neoplasms
2010

Effects of Oral Nonylphenol on Testosterone Production in Rat Leydig Cells

Wu, J-J., Wang, K-L., Mao, I-F., Chen, M-L., Hsia, S-M. & Wang, P. S., 2010, In : 調適醫學. 2, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

2009
13 Citations (Scopus)

Effect of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) hull extracts on testosterone release from rat leydig cells

Hsia, S. M., Tseng, Y. W., Wang, S. W., Kuo, Y. H., Huang, D. W., Wang, P. S. & Chiang, W., May 2009, In : Phytotherapy Research. 23, 5, p. 687-695 9 p.

Research output: Contribution to journalArticle

Coix
Leydig Cells
Testosterone
Luteinizing Hormone
Gonadotropin-Releasing Hormone
2008
17 Citations (Scopus)

Effects of adlay hull extracts on uterine contraction and Ca2+ mobilization in the rat

Hsia, S. M., Kuo, Y. H., Chiang, W. & Wang, P. S., Sep 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 3

Research output: Contribution to journalArticle

Uterine Contraction
Dinoprost
Dysmenorrhea
Muscle Contraction
Smooth Muscle
2007
27 Citations (Scopus)

Effects of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) hull extracts on the secretion of progesterone and estradiol in vivo and in vitro

Hsia, S. M., Yeh, C. L., Kuo, Y. H., Wang, P. S. & Chiang, W., Oct 2007, In : Experimental Biology and Medicine. 232, 9, p. 1181-1194 14 p.

Research output: Contribution to journalArticle

Coix
Progesterone
Estradiol
Cyclic AMP-Dependent Protein Kinases
Enzymes
2006
22 Citations (Scopus)

Downregulation of progesterone biosynthesis in rat granulosa cells by adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) bran extracts

Hsia, S. M., Chiang, W., Kuo, Y. H. & Wang, P. S., May 2006, In : International Journal of Impotence Research. 18, 3, p. 264-274 11 p.

Research output: Contribution to journalArticle

Coix
Granulosa Cells
Progesterone
Down-Regulation
Enzymes
6 Citations (Scopus)

Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells

Chang, L. L., Wun, A. W. S., Hung, C. T., Hsia, S. M., Chiang, W. & Wang, P. S., Nov 2006, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 374, 2, p. 141-152 12 p.

Research output: Contribution to journalArticle

Zona Reticularis
Zona Fasciculata
Corticosterone
Acetone
Pregnenolone