• 1004 Citations
  • 16 h-Index
1990 …2020

Research output per year

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Research Output

  • 1004 Citations
  • 16 h-Index
  • 57 Article
  • 1 Conference contribution
  • 1 Review article
2019

A new histone deacetylase inhibitor enhances radiation sensitivity through the induction of misfolded protein aggregation and autophagy in triple-negative breast cancer

Chiu, H. W., Yeh, Y. L., Ho, S. Y., Wu, Y. H., Wang, B. J., Huang, W. J., Ho, Y. S., Wang, Y. J., Chen, L. C. & Tu, S. H., Nov 1 2019, In : Cancers. 11, 11, 1703.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

DNA primase polypeptide 1 (PRIM1) involves in estrogen-induced breast cancer formation through activation of the G2/M cell cycle checkpoint

Lee, W-H., Chen, L-C., Lee, C-J., Huang, C-C., Ho, Y-S., Yang, P-S., Ho, C-T., Chang, H-L., Lin, I-H., Chang, H-W., Liu, Y-R., Wu, C-H. & Tu, S-H., Feb 1 2019, In : International Journal of Cancer. 144, 3, p. 615-630 16 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Electrospun polylactic acid (PLLA) microtube array membrane (MTAM)-An advanced substrate for anticancer drug screening

Tseng, C. H., Huang, W. T., Chew, C. H., Lai, J. K., Tu, S. H., Wei, P. L., Lee, K. Y., Lai, G. M. & Chen, C. C., Feb 14 2019, In : Materials. 12, 4, 569.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3-induced mitophagy

Lee, W. J., Chen, L. C., Lin, J. H., Cheng, T. C., Kuo, C. C., Wu, C. H., Chang, H. W., Tu, S. H. & Ho, Y. S., Jan 1 2019, In : Cancer Medicine. 8, 10, p. 4821-4835 15 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Membrane protein-regulated networks across human cancers

Lin, C. Y., Lee, C. H., Chuang, Y. H., Lee, J. Y., Chiu, Y. Y., Wu Lee, Y. H., Jong, Y. J., Hwang, J. K., Huang, S. H., Chen, L. C., Wu, C. H., Tu, S. H., Ho, Y. S. & Yang, J. M., Dec 1 2019, In : Nature Communications. 10, 1, 3131.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Proteasome 26s subunit, non-atpase 3 (Psmd3) regulates breast cancer by stabilizing her2 from degradation

Fararjeh, A. S., Chen, L. C., Ho, Y. S., Cheng, T. C., Liu, Y. R., Chang, H. L., Chang, H. W., Wu, C. H. & Tu, S. H., Apr 1 2019, In : Cancers. 11, 4, 527.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Small G protein signalling modulator 2 (SGSM2) is involved in oestrogen receptor-positive breast cancer metastasis through enhancement of migratory cell adhesion via interaction with E-cadherin

Lin, J. H., Lee, W. J., Wu, H. C., Wu, C. H., Chen, L. C., Huang, C. C., Chang, H. L., Cheng, T. C., Chang, H. W., Ho, C. T., Tu, S. H. & Ho, Y. S., Jan 1 2019, In : Cell Adhesion and Migration.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The α9 nicotinic acetylcholine receptor mediates nicotine-induced pd-l1 expression and regulates melanoma cell proliferation and migration

Nguyen, H. D., Liao, Y. C., Ho, Y. S., Chen, L. C., Chang, H. W., Cheng, T. C., Liu, D., Lee, W. R., Shen, S. C., Wu, C. H. & Tu, S. H., Dec 2019, In : Cancers. 11, 12, 1991.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
Open Access
1 Citation (Scopus)
2018
3 Citations (Scopus)

Oestrogen receptor-regulated glutathione S-transferase mu 3 expression attenuates hydrogen peroxide-induced cytotoxicity, which confers tamoxifen resistance on breast cancer cells

Lin, J. H., Tu, S. H., Chen, L. C., Huang, C. C., Chang, H. L., Cheng, T. C., Chang, H. W., Wu, C. H., Wu, H. C. & Ho, Y. S., Jan 1 2018, (Accepted/In press) In : Breast Cancer Research and Treatment.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The impact of the effectiveness of GATA3 as a prognostic factor in breast cancer

Fararjeh, A-FS., Tu, S-H., Chen, L-C., Liu, Y-R., Lin, Y-K., Chang, H-L., Chang, H-W., Wu, C-H., Hwang-Verslues, W. W. & Ho, Y-S., 2018, In : Human Pathology. 80, p. 219-230 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

α-Tocopherol succinate enhances pterostilbene anti-tumor activity in human breast cancer cells in vivo and in vitro

Tam, K. W., Ho, C. T., Tu, S. H., Lee, W. J., Huang, C. S., Chen, C. S., Wu, C. H., Lee, C. H. & Ho, Y. S., 2018, In : Oncotarget. 9, 4, p. 4593-4606 14 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017

An apple a day to prevent cancer formation: Reducing cancer risk with flavonoids

Tu, S-H., Chen, L-C. & Ho, Y-S., Jan 1 2017, In : Journal of Food and Drug Analysis. 25, 1, p. 119-124 6 p.

Research output: Contribution to journalReview article

30 Citations (Scopus)

A polygenic risk score for breast cancer risk in a Taiwanese population

Hsieh, Y. C., Tu, S. H., Su, C. T., Cho, E. C., Wu, C. H., Hsieh, M. C., Lin, S. Y., Liu, Y. R., Hung, C. S. & Chiou, H. Y., May 1 2017, In : Breast Cancer Research and Treatment. 163, 1, p. 131-138 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

A rapid and quantitative method to detect human circulating tumor cells in a preclinical animal model

Tu, S. H., Hsieh, Y. C., Huang, L. C., Lin, C. Y., Hsu, K. W., Hsieh, W. S., Chi, W. M. & Lee, C. H., Jun 23 2017, In : BMC Cancer. 17, 1, 440.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Garcinol sensitizes breast cancer cells to Taxol through the suppression of caspase-3/iPLA2 and NF-κB/Twist1 signaling pathways in a mouse 4T1 breast tumor model

Tu, S. H., Chiou, Y. S., Kalyanam, N., Ho, C. T., Chen, L. C. & Pan, M. H., Mar 1 2017, In : Food and Function. 8, 3, p. 1067-1079 13 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Identification of genes and pathways related to lymphovascular invasion in breast cancer patients: A bioinformatics analysis of gene expression profiles

Klahan, S., Wong, H. S. C., Tu, S. H., Chou, W. H., Zhang, Y. F., Ho, T. F., Liu, C. Y., Yih, S. Y., Lu, H. F., Chen, S. C. C., Huang, C. C. & Chang, W. C., Jan 1 2017, In : Tumor Biology. 39, 6

Research output: Contribution to journalArticle

8 Citations (Scopus)
7 Citations (Scopus)

The learning curve of endoscopic total mastectomy in Taiwan: A multi-center study

Hung, C. S., Chang, S. W., Liao, L. M., Huang, C. C., Tu, S. H., Chen, S. T., Chen, D. R., Kuo, S. J., Lai, H. W., Chou, T. M. & Kuo, Y. L., Jun 1 2017, In : PLoS One. 12, 6, e0178251.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2016
31 Citations (Scopus)

Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylatedp53- induced signals

Tu, S-H., Lin, Y. C., Huang, C-C., Yang, P. S., Chang, H. W., Chang, C. H., Wu, C-H., Chen, L-C. & Ho, Y-S., 2016, In : Oncotarget. 7, 47, p. 77516-77531 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Pu-erh tea attenuates smoking-induced foam cell formation through inhibition of the α9-nicotinic-acetylcholine receptor expression in monocytes: An ex vivo study

Chen, L. C., Chen, M. Y., Tu, S. H., Pan, M. H., Lo, C. Y., Ho, C. T., Wu, C. H. & Ho, Y. S., Apr 1 2016, In : Journal of Functional Foods. 22, p. 132-144 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study

Tu, S. H., Chen, M. Y., Chen, L. C., Mao, Y. T., Ho, C. H., Lee, W. J., Lin, Y-K., Pan, M. H., Lo, C. Y., Chen, C. L., Yen, Y., Whang-Peng, J., Ho, C. T., Wu, C. H. & Ho, Y. S., Apr 27 2016, In : Journal of Agricultural and Food Chemistry. 64, 16, p. 3186-3195 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

Conceptual structure of the Taiwan Chinese version of the EORTC QLQ-C30

Huang, C. C., Tu, S. H., Lien, H. H., Huang, C. S., Wang, P. C. & Chie, W. C., Jan 6 2015, In : Quality of Life Research. 24, 8, p. 1999-2013 15 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface

Cheng, T. C., Tu, S. H., Chen, L. C., Chen, M. Y., Chen, W. Y., Lin, Y-K., Ho, C. T., Lin, S. Y., Wu, C. H. & Ho, Y. S., 2015, In : Oncotarget. 6, 25, p. 21283-21300 18 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1

Jin, G., Lee, S. W., Zhang, X., Cai, Z., Gao, Y., Chou, P. C., Rezaeian, A. H., Han, F., Wang, C. Y., Yao, J. C., Gong, Z., Chan, C. H., Huang, C. Y., Tsai, F. J., Tsai, C. H., Tu, S. H., Wu, C. H., Sarbassov, D. D., Ho, Y. S. & Lin, H. K., Jun 18 2015, In : Molecular Cell. 58, 6, p. 989-1000 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2014

CHRNA9 polymorphisms and smoking exposure synergize to increase the risk of breast cancer in Taiwan

Hsieh, Y. C., Lee, C. H., Tu, S. H., Wu, C. H., Hung, C. S., Hsieh, M. C., Chuang, C. W., Ho, Y. S. & Chiou, H. Y., Nov 1 2014, In : Carcinogenesis. 35, 11, p. 2520-2525 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Estrogen receptor status prediction by gene component regression: A comparative study

Huang, C. C., Chuang, E. Y., Tu, S. H., Lien, H. H., Jeng, J. Y., Liu, J. S., Huang, C. S. & Lai, L. C., 2014, In : International Journal of Data Mining and Bioinformatics. 9, 2, p. 149-171 23 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Refinement of breast cancer risk prediction with concordant leading edge subsets from prognostic gene signatures

Huang, C. C., Tu, S. H., Lien, H. H., Huang, C. S., Huang, C. J., Lai, L. C., Tsai, M. H. & Chuang, E. Y., Sep 1 2014, In : Breast Cancer Research and Treatment. 147, 2, p. 353-370 18 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2013

Alteration of α-tocopherol-associated protein (TAP) expression in human breast epithelial cells during breast cancer development

Tam, K-W., Ho, C. T., Lee, W. J., Tu, S-H., Huang, C. S., Chen, C. S., Lee, C-H., Wu, C-H. & Ho, Y-S., Jun 1 2013, In : Food Chemistry. 138, 2-3, p. 1015-1021 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

A preliminary study of concurrent gains and losses across gene expression profiles and comparative genomic hybridization in Taiwanese breast cancer patients

Huang, C. C., Jeng, J. Y., Tu, S. H., Lien, H. H., Huang, C. S., Lai, L. C. & Chuang, E. Y., Feb 1 2013, In : Translational Cancer Research. 2, 1, p. 18-24 7 p.

Research output: Contribution to journalArticle

Concurrent Gene Signatures for Han Chinese Breast Cancers

Huang, C. C., Tu, S. H., Lien, H. H., Jeng, J. Y., Huang, C. S., Huang, C. J., Lai, L. C. & Chuang, E. Y., Oct 3 2013, In : PLoS One. 8, 10, e76421.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues

Huang, C. S., Ho, C. T., Tu, S. H., Pan, M. H., Chuang, C. H., Chang, H. W., Chang, C. H., Wu, C. H. & Ho, Y. S., May 8 2013, In : Journal of Agricultural and Food Chemistry. 61, 18, p. 4326-4335 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Luteolin sensitises drug-resistant human breast cancer cells to tamoxifen via the inhibition of cyclin E2 expression

Tu, S. H., Ho, C. T., Liu, M. F., Huang, C. S., Chang, H. W., Chang, C. H., Wu, C. H. & Ho, Y. S., 2013, In : Food Chemistry. 141, 2, p. 1553-1561 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Multiclass prediction with partial least square regression for gene expression data: Applications in breast cancer intrinsic taxonomy

Huang, C. C., Tu, S. H., Huang, C. S., Lien, H. H., Lai, L. C. & Chuang, E. Y., 2013, In : BioMed Research International. 2013, 248648.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2012

A novel HLA-A2-restricted CTL epitope of tumor-associated antigen L6 can inhibit tumor growth in vivo

Tu, S. H., Huang, H. I., Lin, S. I., Liu, H. Y., Sher, Y. P., Chiang, S. K., Chong, P., Roffler, S., Tseng, G. C., Chen, H. W. & Liu, S. J., Apr 2012, In : Journal of Immunotherapy. 35, 3, p. 235-244 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Changes in quality of life among newly diagnosed breast cancer patients in Taiwan

Cheng, S. Y., Lai, Y. H., Chen, S. C., Shun, S. C., Liao, Y. M., Tu, S. H., Chen, C. S., Hsiang, C. Y. & Chen, C. M., Jan 2012, In : Journal of Clinical Nursing. 21, 1-2, p. 70-79 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway

Chen, L. C., Tu, S. H., Huang, C. S., Chen, C. S., Ho, C. T., Lin, H. W., Lee, C. H., Chang, H. W., Chang, C. H., Wu, C. H., Lee, W. S. & Ho, Y. S., Aug 2012, In : Breast Cancer Research and Treatment. 134, 3, p. 989-1004 16 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
19 Citations (Scopus)

Prediction consistency and clinical presentations of breast cancer molecular subtypes for Han Chinese population.

Huang, C. C., Tu, S. H., Lien, H. H., Jeng, J. Y., Liu, J. S., Huang, C. S., Wu, Y. Y., Liu, C. Y., Lai, L. C. & Chuang, E. Y., Sep 19 2012, In : Journal of Translational Medicine. 10 Suppl 1, S10.

Research output: Contribution to journalArticle

4 Citations (Scopus)
15 Citations (Scopus)
2011

A model-based circular binary segmentation algorithm for the analysis of array CGH data

Hsu, F. H., Chen, H. I. H., Tsai, M. H., Lai, L. C., Huang, C. C., Tu, S. H., Chuang, E. Y. & Chen, Y., 2011, In : BMC Research Notes. 4, 394.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells

Lee, C. H., Chang, Y. C., Chen, C. S., Tu, S. H., Wang, Y. J., Chen, L. C., Chang, Y. J., Wei, P. L., Chang, H. W., Chang, C. H., Huang, C. S., Wu, C. H. & Ho, Y. S., Sep 2011, In : Breast Cancer Research and Treatment. 129, 2, p. 331-345 15 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins

Chen, C. S., Lee, C-H., Hsieh, C. D., Ho, C. T., Pan, M. H., Huang, C. S., Tu, S-H., Wang, Y. J., Chen, L-C., Chang, Y-J., Wei, P-L., Yang, Y-Y., Wu, C-H. & Ho, Y-S., Jan 2011, In : Breast Cancer Research and Treatment. 125, 1, p. 73-87 15 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells

Tu, S. H., Ku, C. Y., Ho, C. T., Chen, C. S., Huang, C. S., Lee, C. H., Chen, L. C., Pan, M. H., Chang, H. W., Chang, C. H., Chang, Y. J., Wei, P. L., Wu, C. H. & Ho, Y. S., Mar 2011, In : Molecular Nutrition and Food Research. 55, 3, p. 455-466 12 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
2010

Arm exercise promotion scale: Instrument validation

Cheng, S. Y., Tu, S. H., Yang, Y. L., Chen, C. S., Liao, Y. M., Hsiang, C. Y. & Chen, C. M., May 2010, In : Journal of Advanced Nursing. 66, 5, p. 1142-1150 9 p.

Research output: Contribution to journalArticle

Increased expression of enolase α in human breast cancer confers tamoxifen resistance in human breast cancer cells

Tu, S. H., Chang, C. C., Chen, C. S., Tam, K. W., Wang, Y. J., Lee, C. H., Lin, H. W., Cheng, T. C., Huang, C. S., Chu, J. S., Shih, N. Y., Chen, L. C., Leu, S. J., Ho, Y. S. & Wu, C. H., Jun 2010, In : Breast Cancer Research and Treatment. 121, 3, p. 539-553 15 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Long-term ethanol exposure causes human liver cancer cells to become resistant to mitomycin c treatment through the inactivation of bad-mediated apoptosis

Huang, C. S., Lee, Y. R., Chen, C. S., Tu, S. H., Wang, Y. J., Lee, C. H., Chen, L. C., Chang, H. W., Chang, C. H., Su, C-M., Wu, C. H. & Ho, Y. S., Aug 2010, In : Molecular Carcinogenesis. 49, 8, p. 728-738 11 p.

Research output: Contribution to journalArticle

Overexpression and activation of the α9-nicotinic receptor during tumorigenesis in human breast epithelial cells

Lee, C. H., Huang, C. S., Chen, C. S., Tu, S. H., Wang, Y. J., Chang, Y. J., Tam, K. W., Wei, P. L., Cheng, T. C., Chu, J. S., Chen, L. C., Wu, C. H. & Ho, Y. S., Sep 8 2010, In : Journal of the National Cancer Institute. 102, 17, p. 1322-1335 14 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)