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Research Output

  • 1211 Citations
  • 19 h-Index
  • 43 Article
  • 3 Review article
  • 2 Comment/debate
2020
Open Access

Limited effects of antibiotic prophylaxis in patients with Child–Pugh class A/B cirrhosis and upper gastrointestinal bleeding

Chang, T. S., Tsai, Y. H., Lin, Y. H., Chen, C. H., Lu, C. K., Huang, W. S., Yang, Y. H., Chen, W. M., Hsieh, Y. Y., Wu, Y. C., Tung, S. Y. & Huang, Y. H., Jan 1 2020, In : PLoS ONE. 15, 2, e0229101.

Research output: Contribution to journalArticle

Open Access
2019

A double-virally-inactivated (Intercept–solvent/detergent) human platelet lysate for in vitro expansion of human mesenchymal stromal cells

Barro, L., Su, Y. T., Nebie, O., Wu, Y. W., Huang, Y. H., Koh, M. B. C., Knutson, F. & Burnouf, T., Jun 2019, In : Transfusion. 59, 6, p. 2061-2073 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Conceptual development of immunotherapeutic approaches to gastrointestinal cancer

Abolarinwa, B. A., Ibrahim, R. B. & Huang, Y. H., Sep 2 2019, In : International Journal of Molecular Sciences. 20, 18, 4624.

Research output: Contribution to journalReview article

Open Access

DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation

Lai, S. C., Su, Y. T., Chi, C. C., Kuo, Y. C., Lee, K. F., Wu, Y. C., Lan, P. C., Yang, M. H., Chang, T. S. & Huang, Y. H., Nov 26 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 474.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Triple-negative breast cancer: Current understanding and future therapeutic breakthrough targeting cancer stemness

Lee, K. L., Kuo, Y. C., Ho, Y. S. & Huang, Y. H., Sep 2019, In : Cancers. 11, 9, 1334.

Research output: Contribution to journalReview article

Open Access
12 Citations (Scopus)
2018

IGF-1R Promotes Symmetric Self-Renewal and Migration of Alkaline Phosphatase+ Germ Stem Cells through HIF-2α-OCT4/CXCR4 Loop under Hypoxia

Kuo, Y. C., Au, H. K., Hsu, J. L., Wang, H. F., Lee, C. J., Peng, S. W., Lai, S. C., Wu, Y. C., Ho, H. N. & Huang, Y. H., Feb 13 2018, In : Stem Cell Reports. 10, 2, p. 524-537 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2017

Correction: Inflammation promotes expression of stemness-related properties in hbv-related hepatocellular carcinoma (PLoS ONE (2016)11:2 (e0149897) DOI: 10.1371/journal.pone.0149897)

Chang, T. S., Chen, C. L., Wu, Y. C., Liu, J. J., Kuo, Y. C., Lee, K. F., Lin, S. Y., Lin, S. E., Tung, S. Y., Kuo, L. M., Tsai, Y. H. & Huang, Y. H., Jan 1 2017, In : PLoS One. 12, 1, e0171176.

Research output: Contribution to journalComment/debate

Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer

Ling, H. H., Kuo, C. C., Lin, B. X., Huang, Y. H. & Lin, C. W., Jan 1 2017, In : Experimental Cell Research. 350, 1, p. 218-225 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Fluorescent nanodiamonds enable quantitative tracking of human mesenchymal stem cells in miniature pigs

Su, L. J., Wu, M. S., Hui, Y. Y., Chang, B. M., Pan, L., Hsu, P. C., Chen, Y. T., Ho, H. N., Huang, Y. H., Ling, T. Y., Hsu, H. H. & Chang, H. C., Mar 30 2017, In : Scientific Reports. 7, 45607.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ

Lee, W. Y., Chen, P. C., Wu, W. S., Wu, H. C., Lan, C. H., Huang, Y. H., Cheng, C. H., Chen, K. C. & Lin, C. W., 2017, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2016

Inflammation promotes expression of stemness-related properties in HBV-related hepatocellular carcinoma

Chang, T. S., Chen, C. L., Wu, Y. C., Liu, J. J., Kuo, Y. C., Lee, K. F., Lin, S. Y., Lin, S-E., Tung, S. Y., Kuo, L. M., Tsai, Y. H. & Huang, Y. H., Feb 1 2016, In : PLoS One. 11, 2, e0149897.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2015

Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression

Chang, T. S., Wu, Y. C., Chi, C. C., Su, W. C., Chang, P. J., Lee, K. F., Tung, T. H., Wang, J., Liu, J-J., Tung, S. Y., Kuo, L. M., Ho, H. N., Ling, T. Y. & Huang, Y-H., Jan 1 2015, In : Clinical Cancer Research. 21, 1, p. 201-210 10 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Alpha-fetoprotein measurement benefits hepatocellular carcinoma surveillance in patients with cirrhosis

Chang, T. S., Wu, Y. C., Tung, S. Y., Wei, K. L., Hsieh, Y. Y., Huang, H. C., Chen, W. M., Shen, C. H., Lu, C. H., Wu, C. S., Tsai, Y. H. & Huang, Y. H., Jun 10 2015, In : American Journal of Gastroenterology. 110, 6, p. 836-844 9 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Response to Braillon

Chang, T. S., Wu, Y. C., Tsai, Y. H. & Huang, Y. H., Nov 1 2015, In : American Journal of Gastroenterology. 110, 11, p. 1625-1627 3 p.

Research output: Contribution to journalArticle

TGF-βI regulates cell migration through pluripotent transcription factor OCT4 in endometriosis

Au, H. K., Chang, J. H., Wu, Y. C., Kuo, Y. C., Chen, Y. H., Lee, W. C., Chang, T. S., Lan, P. C., Kuo, H. C., Lee, K. L., Lee, M. T., Tzeng, C. R. & Huang, Y. H., Dec 1 2015, In : PLoS One. 10, 12, e0145256.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2014

DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells

Liao, H. F., Chen, W. S. C., Chen, Y. H., Kao, T. H., Tseng, Y. T., Lee, C. Y., Chiu, Y. C., Lee, P. L., Lin, Q. J., Ching, Y. H., Hata, K., Cheng, W. T. K., Tsai, M. H., Sasaki, H., Ho, H. N., Wu, S. C., Huang, Y-H., Yen, P. & Lin, S. P., 2014, In : Development. 141, 12, p. 2402-2413 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
4 Citations (Scopus)

Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells

Huang, Y-H., Lin, M-H., Wang, P. C., Wu, Y. C., Chiang, H. L., Wang, Y. L., Chang, J. H., Huang, Y. K., Gu, S. Y., Ho, H. N. & Ling, T. Y., 2014, In : Molecular Human Reproduction. 20, 6, p. 526-537 12 p., gau016.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013

Expression of the pluripotent transcription factor OCT4 promotes cell migration in endometriosis

Chang, J. H., Au, H. K., Lee, W. C., Chi, C. C., Ling, T. Y., Wang, L. M., Kao, S. H., Huang, Y. H. & Tzeng, C. R., Apr 2013, In : Fertility and Sterility. 99, 5, p. 1332-1339 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2012
4 Citations (Scopus)

Chemotherapeutic sensitivity of testicular germ cell tumors under hypoxic conditions is negatively regulated by SENP1-controlled sumoylation of OCT4

Wu, Y. C., Ling, T. Y., Lu, S. H., Kuo, H. C., Ho, H. N., Yeh, S. D., Shen, C. N. & Huang, Y. H., Oct 1 2012, In : Cancer Research. 72, 19, p. 4963-4973 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Determination of cryoprotectant for magnetic cryopreservation of dental pulp tissue

Lee, S. Y. S., Sun, C. H. B., Kuo, T. F., Huang, Y. H., Jeng, J. H., Yang, J. C. & Yang, W. C. V., Jun 1 2012, In : Tissue Engineering - Part C: Methods. 18, 6, p. 397-407 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Magnetic cryopreservation for dental pulp stem cells

Lee, S. Y., Huang, G. W., Shiung, J. N., Huang, Y. H., Jeng, J. H., Kuo, T. F., Yang, J. C. & Yang, W. C. V., Jun 2012, In : Cells Tissues Organs. 196, 1, p. 23-33 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Meiotic competent human germ cell-like cells derived from human embryonic stem cells induced by BMP4/WNT3A signaling and OCT4/EpCAM (epithelial cell adhesion molecule) selection

Chuang, C. Y., Lin, K. I., Hsiao, M., Stone, L., Chen, H. F., Huang, Y-H., Lin, S. P., Ho, N. N. & Kuo, H. C., Apr 27 2012, In : Journal of Biological Chemistry. 287, 18, p. 14389-14401 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

The cancer marker neutrophil gelatinase-associated lipocalin is highly expressed in human endometrial hyperplasia

Liao, C. J., Huang, Y. H., Au, H. K., Wang, L. M. & Chu, S. T., Feb 2012, In : Molecular Biology Reports. 39, 2, p. 1029-1036 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2011
5 Citations (Scopus)
2010

Capacitation suppression by mouse seminal vesicle autoantigen involves a decrease in plasma membrane Ca2+-ATPase (PMCA)-mediated intracellular calcium

Lu, S. H., Yen, Y. K., Ling, T. Y., Cheng, K. T., Shu, J. A., Au, H. K. & Huang, Y. H., Dec 1 2010, In : Journal of Cellular Biochemistry. 111, 5, p. 1188-1198 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Characterization of a novel cell-surface protein expressed on human sperm

Yang, R. B., Au, H. K., Tzeng, C. R., Tsai, M. T., Wu, P., Wu, Y. C., Ling, T. Y. & Huang, Y. H., Jan 2010, In : Human Reproduction. 25, 1, p. 42-51 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Dental Stem Cells and Tooth Banking for Regenerative Medicine

Huang, Y-H., Yang, J-C., Wang, C. W. & Lee, S-Y., Jun 2010, In : Journal of Experimental and Clinical Medicine(Taiwan). 2, 3, p. 111-117 7 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)

Tracking the rejection and survival of mouse ovarian iso- and allografts in vivo with bioluminescent imaging

Chen, C. H., Yeh, Y. C., Wu, G. J., Huang, Y. H., Lai, W-F., Liu, J. Y. & Tzeng, C. R., 2010, In : Reproduction. 140, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2009

Pluripotency of mouse spermatogonial stem cells maintained by IGF-1- Dependent pathway

Huang, Y-H., Chin, C. C., Ho, N. N., Chou, C. K., Shen, C. N., Kuo, H. C., Wu, T. J., Wu, Y. C., Hung, Y. C., Chang, C. C. & Ling, T. Y., Jul 2009, In : FASEB Journal. 23, 7, p. 2076-2087 12 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)
2008

Anemonin is a natural bioactive compound that can regulate tyrosinase-related proteins and mRNA in human melanocytes

Huang, Y. H., Lee, T. H., Chan, K. J., Hsu, F. L., Wu, Y. C. & Lee, M. H., Feb 2008, In : Journal of Dermatological Science. 49, 2, p. 115-123 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2007

Aberrant expression and distribution of the OCT-4 transcription factor in seminomas

Cheng, C. J., Wu, Y. C., Shu, J. A., Ling, T. Y., Kuo, H. C., Wu, J. Y., Chang, E-E., Chang, S. C. & Huang, Y. H., Nov 2007, In : Journal of Biomedical Science. 14, 6, p. 797-807 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Suppression effect of seminal vesicle autoantigen on platelet-activating factor-induced mouse sperm capacitation

Huang, Y. H., Chen, Y. H., Lin, C. M., Ciou, Y. Y., Kuo, S. P., Chen, C. T., Shih, C. M. & Chang, E-E., Mar 1 2007, In : Journal of Cellular Biochemistry. 100, 4, p. 941-951 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2006

Cosmetic applications of selected traditional Chinese herbal medicines

Wang, K-H., Lin, R. D., Hsu, F-L., Huang, Y-H., Chang, H. C., Huang, C. Y. & Lee, M-H., Jul 19 2006, In : Journal of Ethnopharmacology. 106, 3, p. 353-359 7 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

Down-regulation of fatty acid synthase is associated with decreased Akt activation in lovastatin induced apoptosis cells

Chang, Y. C., Huang, Y. H., Shih, C. M., Wu, J. Y., Liu, C. L., Wang, S. H. & Lin, C. M., Dec 2006, In : Journal of Food and Drug Analysis. 14, 4, p. 340-345 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Effects of cadmium on structure and enzymatic activity of Cu,Zn-SOD and oxidative status in neural cells

Huang, Y-H., Shih, C-M., Huang, C. J., Lin, C-M., Chou, C-M., Tsai, M. L., Liu, T. P., Chiu, J. F. & Chen, C-T., Jun 1 2006, In : Journal of Cellular Biochemistry. 98, 3, p. 577-589 13 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro

Ling, T. Y., Kuo, M. D., Li, C. L., Yu, A. L., Huang, Y. H., Wu, T. J., Lin, Y. C., Chen, S. H. & Yu, J., Jun 20 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 25, p. 9530-9535 6 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

Localization and characterization of an orphan receptor, guanylyl cyclase-G, in mouse testis and sperm

Huang, Y. H., Wei, C. C., Su, Y. H., Wu, B. T., Ciou, Y. Y., Tu, C. F., Cooper, T. G., Yeung, C. H., Chu, S. T., Tsai, M. T. & Yang, R. B., 2006, In : Endocrinology. 147, 10, p. 4792-4800 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2005

Signals of seminal vesicle autoantigen suppresses bovine serum albumin-induced capacitation in mouse sperm

Huang, Y. H., Kuo, S. P., Lin, M. H., Shih, C. M., Chu, S. T., Wei, C. C., Wu, T. J. & Chen, Y. H., Dec 23 2005, In : Biochemical and Biophysical Research Communications. 338, 3, p. 1564-1571 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2004

Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1

Ling, T. Y., Chen, C. L., Huang, Y. H., Liu, I. H., Huang, S. S. & Huang, J. S., Sep 10 2004, In : Journal of Biological Chemistry. 279, 37, p. 38736-38748 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2003

Cellular growth inhibition by IGFBP-3 and TGF-β1 requires LRP-1

Huang, S. S., Ling, T. Y., Tseng, W. F., Huang, Y. H., Tang, F. M., Leal, S. M. & Huang, J. S., Nov 2003, In : FASEB Journal. 17, 14, p. 2068-2081 14 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)

Cloning, Expression, Characterization, and Role in Autocrine Cell Growth of Cell Surface Retention Sequence Binding Protein-1

Huang, S. S., Tang, F. M., Huang, Y. H., Liu, I. H., Hsu, S. C., Chen, S. T. & Huang, J. S., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43855-43869 15 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Fatty acids modulate transforming growth factor-beta activity and plasma clearance.

Ling, T. Y., Huang, Y. H., Lai, M. C., Huang, S. S. & Huang, J. S., 2003, In : FASEB Journal. 17, 11, p. 1559-1561 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2000

A seminal vesicle autoantigen of mouse is able to suppress sperm capacitation-related events stimulated by serum albumin

Huang, Y. H., Chu, S. T. & Chen, Y. H., 2000, In : Biology of Reproduction. 63, 5, p. 1562-1566 5 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
1999
29 Citations (Scopus)
1995

The protein conformation and a zinc-binding domain of an autoantigen from mouse seminal vesicle

Huang, Y. H., Luo, C. W., Yu, L. C., Chu, S. T. & Chen, Y. H., 1995, In : Biophysical Journal. 69, 5, p. 2084-2089 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)