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Research Output 1995 2019

  • 1128 Citations
  • 19 h-Index
  • 41 Article
  • 1 Comment/debate
  • 1 Review article
2019
2 Citations (Scopus)

A double-virally-inactivated (Intercept–solvent/detergent) human platelet lysate for in vitro expansion of human mesenchymal stromal cells

Barro, L., Su, Y. T., Nebie, O., Wu, Y. W., Huang, Y. H., Koh, M. B. C., Knutson, F. & Burnouf, T., Jan 1 2019, In : Transfusion.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Detergents
Blood Platelets
Serum
In Vitro Techniques
2018
7 Citations (Scopus)

IGF-1R Promotes Symmetric Self-Renewal and Migration of Alkaline Phosphatase+ Germ Stem Cells through HIF-2α-OCT4/CXCR4 Loop under Hypoxia

Kuo, Y. C., Au, H. K., Hsu, J. L., Wang, H. F., Lee, C. J., Peng, S. W., Lai, S. C., Wu, Y. C., Ho, H. N. & Huang, Y. H., Feb 13 2018, In : Stem Cell Reports. 10, 2, p. 524-537 14 p.

Research output: Contribution to journalArticle

Stem cells
Germ Cells
Alkaline Phosphatase
Stem Cells
Insulin-Like Growth Factor I
2017

Correction: Inflammation promotes expression of stemness-related properties in hbv-related hepatocellular carcinoma (PLoS ONE (2016)11:2 (e0149897) DOI: 10.1371/journal.pone.0149897)

Chang, T. S., Chen, C. L., Wu, Y. C., Liu, J. J., Kuo, Y. C., Lee, K. F., Lin, S. Y., Lin, S. E., Tung, S. Y., Kuo, L. M., Tsai, Y. H. & Huang, Y. H., Jan 1 2017, In : PLoS One. 12, 1, e0171176.

Research output: Contribution to journalComment/debate

Organized Financing
hepatoma
funding
Hepatocellular Carcinoma
inflammation
29 Citations (Scopus)

Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer

Ling, H. H., Kuo, C. C., Lin, B. X., Huang, Y. H. & Lin, C. W., Jan 1 2017, In : Experimental Cell Research. 350, 1, p. 218-225 8 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Colorectal Neoplasms
Neoplasms
Proteins
Neoplasm Metastasis
19 Citations (Scopus)

Fluorescent nanodiamonds enable quantitative tracking of human mesenchymal stem cells in miniature pigs

Su, L. J., Wu, M. S., Hui, Y. Y., Chang, B. M., Pan, L., Hsu, P. C., Chen, Y. T., Ho, H. N., Huang, Y. H., Ling, T. Y., Hsu, H. H. & Chang, H. C., Mar 30 2017, In : Scientific Reports. 7, 45607.

Research output: Contribution to journalArticle

Nanodiamonds
Mesenchymal Stromal Cells
Swine
Placenta
Stem Cells
12 Citations (Scopus)

Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ

Lee, W. Y., Chen, P. C., Wu, W. S., Wu, H. C., Lan, C. H., Huang, Y. H., Cheng, C. H., Chen, K. C. & Lin, C. W., 2017, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Histone Deacetylase Inhibitors
gefitinib
panobinostat
2016
15 Citations (Scopus)

Inflammation promotes expression of stemness-related properties in HBV-related hepatocellular carcinoma

Chang, T. S., Chen, C. L., Wu, Y. C., Liu, J. J., Kuo, Y. C., Lee, K. F., Lin, S. Y., Lin, S-E., Tung, S. Y., Kuo, L. M., Tsai, Y. H. & Huang, Y. H., Feb 1 2016, In : PLoS One. 11, 2, e0149897.

Research output: Contribution to journalArticle

Octamer Transcription Factors
hepatoma
Viruses
Hepatitis B virus
Hepatocellular Carcinoma
2015
46 Citations (Scopus)

Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression

Chang, T. S., Wu, Y. C., Chi, C. C., Su, W. C., Chang, P. J., Lee, K. F., Tung, T. H., Wang, J., Liu, J-J., Tung, S. Y., Kuo, L. M., Ho, H. N., Ling, T. Y. & Huang, Y-H., Jan 1 2015, In : Clinical Cancer Research. 21, 1, p. 201-210 10 p.

Research output: Contribution to journalArticle

IGF Type 1 Receptor
Hepatitis B virus
Hepatocellular Carcinoma
Interleukin-6
RNA Interference
43 Citations (Scopus)

Alpha-fetoprotein measurement benefits hepatocellular carcinoma surveillance in patients with cirrhosis

Chang, T. S., Wu, Y. C., Tung, S. Y., Wei, K. L., Hsieh, Y. Y., Huang, H. C., Chen, W. M., Shen, C. H., Lu, C. H., Wu, C. S., Tsai, Y. H. & Huang, Y. H., Jun 10 2015, In : American Journal of Gastroenterology. 110, 6, p. 836-844 9 p.

Research output: Contribution to journalArticle

alpha-Fetoproteins
Hepatocellular Carcinoma
Fibrosis
Fetal Proteins
Liver Cirrhosis

Response to Braillon

Chang, T. S., Wu, Y. C., Tsai, Y. H. & Huang, Y. H., Nov 1 2015, In : American Journal of Gastroenterology. 110, 11, p. 1625-1627 3 p.

Research output: Contribution to journalArticle

alpha-Fetoproteins
Liver Neoplasms
Tumor Biomarkers
Early Detection of Cancer
Liver Cirrhosis
19 Citations (Scopus)

TGF-βI regulates cell migration through pluripotent transcription factor OCT4 in endometriosis

Au, H. K., Chang, J. H., Wu, Y. C., Kuo, Y. C., Chen, Y. H., Lee, W. C., Chang, T. S., Lan, P. C., Kuo, H. C., Lee, K. L., Lee, M. T., Tzeng, C. R. & Huang, Y. H., Dec 1 2015, In : PLoS One. 10, 12, e0145256.

Research output: Contribution to journalArticle

transforming growth factors
Transforming Growth Factors
Endometriosis
cell movement
Cell Movement
2014
25 Citations (Scopus)

DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells

Liao, H. F., Chen, W. S. C., Chen, Y. H., Kao, T. H., Tseng, Y. T., Lee, C. Y., Chiu, Y. C., Lee, P. L., Lin, Q. J., Ching, Y. H., Hata, K., Cheng, W. T. K., Tsai, M. H., Sasaki, H., Ho, H. N., Wu, S. C., Huang, Y-H., Yen, P. & Lin, S. P., 2014, In : Development. 141, 12, p. 2402-2413 12 p.

Research output: Contribution to journalArticle

Methyltransferases
Stem Cells
DNA
Zinc Fingers
Leukemia
3 Citations (Scopus)
Bicuspid
Tooth
Elastic Modulus
Cell Count
10 Citations (Scopus)

Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells

Huang, Y-H., Lin, M-H., Wang, P. C., Wu, Y. C., Chiang, H. L., Wang, Y. L., Chang, J. H., Huang, Y. K., Gu, S. Y., Ho, H. N. & Ling, T. Y., 2014, In : Molecular Human Reproduction. 20, 6, p. 526-537 12 p., gau016.

Research output: Contribution to journalArticle

Somatomedin Receptors
Stem Cells
Germ Cells
IGF Type 1 Receptor
Maintenance
2013
31 Citations (Scopus)

Expression of the pluripotent transcription factor OCT4 promotes cell migration in endometriosis

Chang, J. H., Au, H. K., Lee, W. C., Chi, C. C., Ling, T. Y., Wang, L. M., Kao, S. H., Huang, Y. H. & Tzeng, C. R., Apr 2013, In : Fertility and Sterility. 99, 5, p. 1332-1339 8 p.

Research output: Contribution to journalArticle

Endometriosis
Endometrium
Cell Movement
Transcription Factors
Choristoma
2012
3 Citations (Scopus)
Fertility Preservation
Germ Cells
Transgenic Mice
Cell Transplantation
Transplantation
25 Citations (Scopus)

Chemotherapeutic sensitivity of testicular germ cell tumors under hypoxic conditions is negatively regulated by SENP1-controlled sumoylation of OCT4

Wu, Y. C., Ling, T. Y., Lu, S. H., Kuo, H. C., Ho, H. N., Yeh, S. D., Shen, C. N. & Huang, Y. H., Oct 1 2012, In : Cancer Research. 72, 19, p. 4963-4973 11 p.

Research output: Contribution to journalArticle

Sumoylation
Drug Resistance
Embryonal Carcinoma Stem Cells
Protein Stability
Bleomycin
7 Citations (Scopus)

Determination of cryoprotectant for magnetic cryopreservation of dental pulp tissue

Lee, S. Y. S., Sun, C. H. B., Kuo, T. F., Huang, Y. H., Jeng, J. H., Yang, J. C. & Yang, W. C. V., Jun 1 2012, In : Tissue Engineering - Part C: Methods. 18, 6, p. 397-407 11 p.

Research output: Contribution to journalArticle

Dental Pulp
Cryopreservation
Pulp
Tooth
Tissue
35 Citations (Scopus)

Magnetic cryopreservation for dental pulp stem cells

Lee, S. Y., Huang, G. W., Shiung, J. N., Huang, Y. H., Jeng, J. H., Kuo, T. F., Yang, J. C. & Yang, W. C. V., Jun 2012, In : Cells Tissues Organs. 196, 1, p. 23-33 11 p.

Research output: Contribution to journalArticle

Dental Pulp
Cryopreservation
Stem Cells
Dimethyl Sulfoxide
Mesenchymal Stromal Cells
36 Citations (Scopus)

Meiotic competent human germ cell-like cells derived from human embryonic stem cells induced by BMP4/WNT3A signaling and OCT4/EpCAM (epithelial cell adhesion molecule) selection

Chuang, C. Y., Lin, K. I., Hsiao, M., Stone, L., Chen, H. F., Huang, Y-H., Lin, S. P., Ho, N. N. & Kuo, H. C., Apr 27 2012, In : Journal of Biological Chemistry. 287, 18, p. 14389-14401 13 p.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Stem cells
Germ Cells
Cells
Epithelial Cells
12 Citations (Scopus)

The cancer marker neutrophil gelatinase-associated lipocalin is highly expressed in human endometrial hyperplasia

Liao, C. J., Huang, Y. H., Au, H. K., Wang, L. M. & Chu, S. T., Feb 2012, In : Molecular Biology Reports. 39, 2, p. 1029-1036 8 p.

Research output: Contribution to journalArticle

Endometrial Hyperplasia
Adenomyosis
Catenins
Vimentin
Cadherins
2011
5 Citations (Scopus)
Dental Pulp
Cryopreservation
Incisor
Tooth
Odontoblasts
2010
5 Citations (Scopus)

Capacitation suppression by mouse seminal vesicle autoantigen involves a decrease in plasma membrane Ca2+-ATPase (PMCA)-mediated intracellular calcium

Lu, S. H., Yen, Y. K., Ling, T. Y., Cheng, K. T., Shu, J. A., Au, H. K. & Huang, Y. H., Dec 1 2010, In : Journal of Cellular Biochemistry. 111, 5, p. 1188-1198 11 p.

Research output: Contribution to journalArticle

Calcium-Transporting ATPases
Cell membranes
Cell Membrane
Calcium
Sphingomyelins
8 Citations (Scopus)

Characterization of a novel cell-surface protein expressed on human sperm

Yang, R. B., Au, H. K., Tzeng, C. R., Tsai, M. T., Wu, P., Wu, Y. C., Ling, T. Y. & Huang, Y. H., Jan 2010, In : Human Reproduction. 25, 1, p. 42-51 10 p.

Research output: Contribution to journalArticle

Spermatozoa
Membrane Proteins
Sperm-Ovum Interactions
Oocytes
Testis
12 Citations (Scopus)

Dental Stem Cells and Tooth Banking for Regenerative Medicine

Huang, Y-H., Yang, J-C., Wang, C. W. & Lee, S-Y., Jun 2010, In : Journal of Experimental and Clinical Medicine(Taiwan). 2, 3, p. 111-117 7 p.

Research output: Contribution to journalReview article

Regenerative Medicine
Tooth
Stem Cells
Dental Pulp
Dental Sac
7 Citations (Scopus)

Tracking the rejection and survival of mouse ovarian iso- and allografts in vivo with bioluminescent imaging

Chen, C. H., Yeh, Y. C., Wu, G. J., Huang, Y. H., Lai, W-F., Liu, J. Y. & Tzeng, C. R., 2010, In : Reproduction. 140, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

Isografts
Allografts
Luciferases
Transplants
Cyclosporine
2009
79 Citations (Scopus)

Pluripotency of mouse spermatogonial stem cells maintained by IGF-1- Dependent pathway

Huang, Y-H., Chin, C. C., Ho, N. N., Chou, C. K., Shen, C. N., Kuo, H. C., Wu, T. J., Wu, Y. C., Hung, Y. C., Chang, C. C. & Ling, T. Y., Jul 2009, In : FASEB Journal. 23, 7, p. 2076-2087 12 p.

Research output: Contribution to journalArticle

Somatomedins
Stem cells
Stem Cells
Alkaline Phosphatase
Leydig Cells
2008
22 Citations (Scopus)

Anemonin is a natural bioactive compound that can regulate tyrosinase-related proteins and mRNA in human melanocytes

Huang, Y. H., Lee, T. H., Chan, K. J., Hsu, F. L., Wu, Y. C. & Lee, M. H., Feb 2008, In : Journal of Dermatological Science. 49, 2, p. 115-123 9 p.

Research output: Contribution to journalArticle

Monophenol Monooxygenase
Melanocytes
Messenger RNA
Melanins
Proteins
2007
19 Citations (Scopus)

Aberrant expression and distribution of the OCT-4 transcription factor in seminomas

Cheng, C. J., Wu, Y. C., Shu, J. A., Ling, T. Y., Kuo, H. C., Wu, J. Y., Chang, E-E., Chang, S. C. & Huang, Y. H., Nov 2007, In : Journal of Biomedical Science. 14, 6, p. 797-807 11 p.

Research output: Contribution to journalArticle

Seminoma
Transcription Factors
Cells
Tumors
Stem cells
12 Citations (Scopus)

Suppression effect of seminal vesicle autoantigen on platelet-activating factor-induced mouse sperm capacitation

Huang, Y. H., Chen, Y. H., Lin, C. M., Ciou, Y. Y., Kuo, S. P., Chen, C. T., Shih, C. M. & Chang, E-E., Mar 1 2007, In : Journal of Cellular Biochemistry. 100, 4, p. 941-951 11 p.

Research output: Contribution to journalArticle

Sperm Capacitation
Platelet Activating Factor
Spermatozoa
Phosphorylation
Tyrosine
2006
138 Citations (Scopus)

Cosmetic applications of selected traditional Chinese herbal medicines

Wang, K-H., Lin, R. D., Hsu, F-L., Huang, Y-H., Chang, H. C., Huang, C. Y. & Lee, M-H., Jul 19 2006, In : Journal of Ethnopharmacology. 106, 3, p. 353-359 7 p.

Research output: Contribution to journalArticle

Herbal Medicine
Monophenol Monooxygenase
Cosmetics
Sophora
Skin
2 Citations (Scopus)

Down-regulation of fatty acid synthase is associated with decreased Akt activation in lovastatin induced apoptosis cells

Chang, Y. C., Huang, Y. H., Shih, C. M., Wu, J. Y., Liu, C. L., Wang, S. H. & Lin, C. M., Dec 2006, In : Journal of Food and Drug Analysis. 14, 4, p. 340-345 6 p.

Research output: Contribution to journalArticle

lovastatin
Lovastatin
Fatty Acid Synthases
fatty-acid synthase
Down-Regulation
69 Citations (Scopus)

Effects of cadmium on structure and enzymatic activity of Cu,Zn-SOD and oxidative status in neural cells

Huang, Y-H., Shih, C-M., Huang, C. J., Lin, C-M., Chou, C-M., Tsai, M. L., Liu, T. P., Chiu, J. F. & Chen, C-T., Jun 1 2006, In : Journal of Cellular Biochemistry. 98, 3, p. 577-589 13 p.

Research output: Contribution to journalArticle

Cadmium
Proteins
Enzyme activity
Amyotrophic Lateral Sclerosis
Enzymes
104 Citations (Scopus)

Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro

Ling, T. Y., Kuo, M. D., Li, C. L., Yu, A. L., Huang, Y. H., Wu, T. J., Lin, Y. C., Chen, S. H. & Yu, J., Jun 20 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 25, p. 9530-9535 6 p.

Research output: Contribution to journalArticle

Octamer Transcription Factors
Coronavirus Infections
SARS Virus
Stem Cells
Lung
14 Citations (Scopus)

Localization and characterization of an orphan receptor, guanylyl cyclase-G, in mouse testis and sperm

Huang, Y. H., Wei, C. C., Su, Y. H., Wu, B. T., Ciou, Y. Y., Tu, C. F., Cooper, T. G., Yeung, C. H., Chu, S. T., Tsai, M. T. & Yang, R. B., 2006, In : Endocrinology. 147, 10, p. 4792-4800 9 p.

Research output: Contribution to journalArticle

Spermatozoa
Testis
Neutralizing Antibodies
Guanylate Cyclase-Coupled Receptors
Sperm Transport
2005
19 Citations (Scopus)

Signals of seminal vesicle autoantigen suppresses bovine serum albumin-induced capacitation in mouse sperm

Huang, Y. H., Kuo, S. P., Lin, M. H., Shih, C. M., Chu, S. T., Wei, C. C., Wu, T. J. & Chen, Y. H., Dec 23 2005, In : Biochemical and Biophysical Research Communications. 338, 3, p. 1564-1571 8 p.

Research output: Contribution to journalArticle

Bovine Serum Albumin
Spermatozoa
Sperm Capacitation
Phosphorylation
Tyrosine
2004
10 Citations (Scopus)

Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1

Ling, T. Y., Chen, C. L., Huang, Y. H., Liu, I. H., Huang, S. S. & Huang, J. S., Sep 10 2004, In : Journal of Biological Chemistry. 279, 37, p. 38736-38748 13 p.

Research output: Contribution to journalArticle

Annexin A6
Low Density Lipoprotein Receptor-Related Protein-1
Binding Sites
Ligands
Growth
2003
113 Citations (Scopus)

Cellular growth inhibition by IGFBP-3 and TGF-β1 requires LRP-1

Huang, S. S., Ling, T. Y., Tseng, W. F., Huang, Y. H., Tang, F. M., Leal, S. M. & Huang, J. S., Nov 2003, In : FASEB Journal. 17, 14, p. 2068-2081 14 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 3
insulin-like growth factor binding proteins
growth retardation
Growth
receptors
17 Citations (Scopus)

Cloning, Expression, Characterization, and Role in Autocrine Cell Growth of Cell Surface Retention Sequence Binding Protein-1

Huang, S. S., Tang, F. M., Huang, Y. H., Liu, I. H., Hsu, S. C., Chen, S. T. & Huang, J. S., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43855-43869 15 p.

Research output: Contribution to journalArticle

Cloning
Cell growth
Organism Cloning
Carrier Proteins
Cells
9 Citations (Scopus)

Fatty acids modulate transforming growth factor-beta activity and plasma clearance.

Ling, T. Y., Huang, Y. H., Lai, M. C., Huang, S. S. & Huang, J. S., 2003, In : FASEB Journal. 17, 11, p. 1559-1561 3 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta
alpha-Macroglobulins
Fatty Acids
Thermodynamic properties
Plasmas
2000
43 Citations (Scopus)

A seminal vesicle autoantigen of mouse is able to suppress sperm capacitation-related events stimulated by serum albumin

Huang, Y. H., Chu, S. T. & Chen, Y. H., 2000, In : Biology of Reproduction. 63, 5, p. 1562-1566 5 p.

Research output: Contribution to journalArticle

Sperm Capacitation
Serum Albumin
Spermatozoa
Tyrosine
Phosphorylation
1999
29 Citations (Scopus)
Seminal Vesicles
Sperm Motility
Phospholipids
Carrier Proteins
Epithelium
1995
13 Citations (Scopus)

The protein conformation and a zinc-binding domain of an autoantigen from mouse seminal vesicle

Huang, Y. H., Luo, C. W., Yu, L. C., Chu, S. T. & Chen, Y. H., 1995, In : Biophysical Journal. 69, 5, p. 2084-2089 6 p.

Research output: Contribution to journalArticle

Protein Conformation
Zinc
Fluorescence
Circular Dichroism
Proteins