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Research Output 1997 2019

  • 1636 Citations
  • 22 h-Index
  • 105 Article
  • 1 Chapter
2019
1 Citation (Scopus)

Antidepressants Reduced Risk of Mortality in Patients With Diabetes Mellitus: A Population-Based Cohort Study in Taiwan

Chen, H. M., Yang, Y. H., Chen, K. J., Lee, Y., McIntyre, R. S., Lu, M. L., Lee, Y. C., Hsieh, M. C. & Chen, V. C. H., Oct 1 2019, In : The Journal of clinical endocrinology and metabolism. 104, 10, p. 4619-4625 7 p.

Research output: Contribution to journalArticle

Medical problems
Taiwan
Antidepressive Agents
Hazards
Diabetes Mellitus

Antidepressant use and hepatocellular carcinoma in patients with hepatitis C who had received interferon therapy: A population-based cohort study

Chen, V. C. H., Lu, M. L., Yang, Y. H., Weng, J. C. & Chang, C. C., Jun 15 2019, In : Journal of Affective Disorders. 253, p. 147-153 7 p.

Research output: Contribution to journalArticle

Hepatitis C
Interferons
Antidepressive Agents
Hepatocellular Carcinoma
Cohort Studies
1 Citation (Scopus)

Antipsychotic use is inversely associated with gastric cancer risk: A nationwide population-based nested case-control study

Hsieh, Y. H., Chan, H. L., Lin, C. F., Liang, S. H. Y., Lu, M. L., McIntyre, R. S., Lee, Y., Lin, T. C., Chiu, W. C. & Chen, V. C. H., Aug 1 2019, In : Cancer Medicine. 8, 9, p. 4484-4496 13 p.

Research output: Contribution to journalArticle

Open Access
Antipsychotic Agents
Stomach Neoplasms
Case-Control Studies
Population
olanzapine

Attention-Deficit/Hyperactivity Disorder and Mortality Risk in Taiwan

Chen, V. C. H., Chan, H. L., Wu, S. I., Lee, M., Lu, M. L., Liang, H. Y., Dewey, M. E., Stewart, R. & Lee, C. T. C., Aug 7 2019, In : JAMA network open. 2, 8, e198714.

Research output: Contribution to journalArticle

Open Access
Attention Deficit Disorder with Hyperactivity
Taiwan
Mortality
Homicide
Wounds and Injuries
2 Citations (Scopus)

Exploration of microbiota targets for major depressive disorder and mood related traits

Chung, Y. C. E., Chen, H. C., Chou, H. C. L., Chen, I. M., Lee, M. S., Chuang, L. C., Liu, Y. W., Lu, M. L., Chen, C. H., Wu, C. H., Huang, M. C., Liao, S. C., Ni, Y. H., Lai, M. S., Shih, W. L. & Kuo, P. H., Apr 1 2019, In : Journal of Psychiatric Research. 111, p. 74-82 9 p.

Research output: Contribution to journalArticle

Microbiota
Major Depressive Disorder
Depression
Anxiety
Fats

Homocysteine, rather than age of onset, is a better predictor for cognitive function in older adults with bipolar disorder

Chen, P-H., Liu, H-C., Lu, M-L., Chen, C-H., Chang, C-J., Chiu, W-C., Sun, I-W., Liu, S-I., Tsai, S-Y., Chiu, C-C. & Stewart, R., May 21 2019, In : International Journal of Geriatric Psychiatry.

Research output: Contribution to journalArticle

Homocysteine
Bipolar Disorder
Age of Onset
Cognition
Blood Vessels
1 Citation (Scopus)
Treatment-Resistant Depressive Disorder
Depressive Disorder
Meta-Analysis
Safety
Depression

New use for old drugs: The protective effect of atypical antipsychotics on hepatocellular carcinoma

Chen, V. C. H., Chan, H. L., Hsu, T. C., Lu, M. L., Lee, Y. C., Lee, Y., Siow, J. Y., McIntyre, R. S., Zhou, A. J., Tzang, B. S. & Lee, C. T. C., 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Protective Agents
Antipsychotic Agents
Hepatocellular Carcinoma
Risperidone
Clozapine
1 Citation (Scopus)
olanzapine
Psychopathology
Schizophrenia
Quality of Life
Pharmacology

Orexin-A Levels in Relation to the Risk of Metabolic Syndrome in Patients with Schizophrenia Taking Antipsychotics

Chen, P-Y., Chen, C-H., Chang, C-K., Kao, C-F., Lu, M-L., Lin, S-K., Huang, M-C., Hwang, L-L. & Mondelli, V., Jan 1 2019, In : International Journal of Neuropsychopharmacology. 22, 1, p. 28-36 9 p.

Research output: Contribution to journalArticle

Antipsychotic Agents
Schizophrenia
Clozapine
Metabolome
Odds Ratio

Relationship between metabolic syndrome and acylated/desacylated ghrelin ratio in patients with schizophrenia under olanzapine medication

Wu, T. H., Chiu, C. C., Goh, K. K., Chen, P. Y., Huang, M. C., Chen, C. H. & Lu, M. L., Jan 1 2019, (Accepted/In press) In : Journal of Psychopharmacology.

Research output: Contribution to journalArticle

Open Access
olanzapine
Ghrelin
Schizophrenia
Homeostasis
1 Citation (Scopus)

Risk of schizophrenia among people with obsessive-compulsive disorder: A nationwide population-based cohort study

Cheng, Y. F., Chen, V. C. H., Yang, Y. H., Chen, K. J., Lee, Y. C. & Lu, M. L., Jan 1 2019, In : Schizophrenia Research.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Schizophrenia
Cohort Studies
Population
Comorbidity

The association between the sedative loads and clinical severity indicators in the first-onset major depressive disorder

Wang, Y. C., Lin, H. T., Lu, M. L., Huang, M. C., Chen, C. H., Wu, T. H., Wang, S., Mao, W. C., Kuo, P. H. & Chen, H. C., Jan 1 2019, In : Frontiers in Psychiatry. 10, MAR, p. 129 129.

Research output: Contribution to journalArticle

Open Access
Major Depressive Disorder
Hypnotics and Sedatives
Antidepressive Agents
Lorazepam
Anxiety Disorders

Transcriptome changes in relation to manic episode

Lee, Y. C., Chao, Y. L., Chang, C. E., Hsieh, M. H., Liu, K. T., Chen, H. C., Lu, M. L., Chen, W. Y., Chen, C. H., Tsai, M. H., Lu, T. P., Huang, M. C. & Kuo, P. H., Jan 1 2019, In : Frontiers in Psychiatry. 10, MAY, 280.

Research output: Contribution to journalArticle

Open Access
Bipolar Disorder
Transcriptome
Genes
RNA Sequence Analysis
Long Noncoding RNA
2018
8 Citations (Scopus)
olanzapine
Schizophrenia
Drug Monitoring
C-Peptide
Waist Circumference

Association between enterovirus infection and speech and language impairments: A nationwide population-based study

Hung, T. H., Chen, V. C. H., Yang, Y. H., Tsai, C. S., Lu, M. L., McIntyre, R. S., Lee, Y. & Huang, K. Y., Jun 1 2018, In : Research in Developmental Disabilities. 77, p. 76-86 11 p.

Research output: Contribution to journalArticle

Enterovirus Infections
Language
Population
Taiwan
Hospitalization
2 Citations (Scopus)

Diseases of the pancreas and suicide mortality: A nationwide nested case-control study among patients with mental health disorders in Taiwan

Chen, H. M., Chen, V. C. H., Wang, T. N., Lu, M. L., Huang, Y. C., Dewey, M. E., Lee, J. K. W. & Tsai, C. P., Jan 1 2018, In : General Hospital Psychiatry. 50, p. 45-50 6 p.

Research output: Contribution to journalArticle

Taiwan
Mental Disorders
Suicide
Case-Control Studies
Pancreas
9 Citations (Scopus)
Fluvoxamine
compound A 12
Clozapine
Psychopathology
Schizophrenia
8 Citations (Scopus)

Leptin/Adiponectin ratio as a potential biomarker for metabolic syndrome in patients with schizophrenia

Chen, V. C. H., Chen, C. H., Chiu, Y. H., Lin, T. Y., Li, F. C. & Lu, M. L., Jun 1 2018, In : Psychoneuroendocrinology. 92, p. 34-40 7 p.

Research output: Contribution to journalArticle

Adiponectin
Leptin
Schizophrenia
Biomarkers
olanzapine

Prostate cancer and antidepressants: A nationwide population-based nested case-control study

Lin, W. Y., Chen, V. C. H., Chiu, W. C., Yim, S. J., Ho, P. T., McIntyre, R. S., Lu, M. L. & Wu, S. I., Feb 1 2018, In : Journal of Affective Disorders. 227, p. 834-839 6 p.

Research output: Contribution to journalArticle

Antidepressive Agents
Case-Control Studies
Prostatic Neoplasms
Population
Logistic Models
5 Citations (Scopus)

Risk profiles of personality traits for suicidality among mood disorder patients and community controls

Su, M. H., Chen, H. C., Lu, M. L., Feng, J., Chen, I. M., Wu, C. S., Chang, S. W. & Kuo, P. H., Jan 1 2018, In : Acta Psychiatrica Scandinavica. 137, 1, p. 30-38 9 p.

Research output: Contribution to journalArticle

Mood Disorders
Personality
Suicidal Ideation
Suicide
Logistic Models
4 Citations (Scopus)
Antipsychotic Agents
Weight Gain
Meta-Analysis
Schizophrenia
Randomized Controlled Trials
1 Citation (Scopus)

‘Cool’ and ‘Hot’ executive functions in suicide attempters with major depressive disorder

Ho, M. C., Hsu, Y. C., Lu, M. L., Gossop, M. & Chen, V. C. H., Aug 1 2018, In : Journal of Affective Disorders. 235, p. 332-340 9 p.

Research output: Contribution to journalArticle

Executive Function
Major Depressive Disorder
Suicide
Depression
Suicidal Ideation
2017
7 Citations (Scopus)

Assessment of brain functional connectome alternations and correlation with depression and anxiety in major depressive disorders

Chen, V. C. H., Shen, C. Y., Liang, S. H. Y., Li, Z. H., Hsieh, M. H., Tyan, Y. S., Lu, M. L., Lee, Y., McIntyre, R. S. & Weng, J. C., Jan 1 2017, In : PeerJ. 2017, 11, e3147.

Research output: Contribution to journalArticle

Connectome
amygdala
rating scales
Major Depressive Disorder
anxiety
6 Citations (Scopus)

Asthma, corticosteroid use and schizophrenia: A nationwide populationbased study in Taiwan

Wang, W. C., Lu, M. L., Chen, V. C. H., Ng, M. H., Huang, K. Y., Hsieh, M. H., Hsieh, M. J., Mcintyre, R. S., Lee, Y. & Lee, C. T. C., Mar 1 2017, In : PLoS One. 12, 3, e0173063.

Research output: Contribution to journalArticle

national surveys
asthma
adrenal cortex hormones
Taiwan
Schizophrenia
4 Citations (Scopus)

Bipolar disorder and the risk of fracture: A nationwide population-based cohort study

Su, J. A., Cheng, B. H., Huang, Y. C., Lee, C. P., Yang, Y. H., Lu, M. L., Hsu, C. Y., Lee, Y., McIntyre, R. S., Chin Lin, T. & Chin-Hung Chen, V., Aug 15 2017, In : Journal of Affective Disorders. 218, p. 246-252 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Cohort Studies
Population
Antipsychotic Agents
Bone Fractures
3 Citations (Scopus)

Evaluation of the interaction between genetic variants of GAD1 and miRNA in bipolar disorders

Chung, Y-C. E., Chen, S-C., Chuang, L-C., Shih, W-L., Chiu, Y-H., Lu, M-L., Chen, H-C. & Kuo, P-H., Jul 10 2017, In : Journal of Affective Disorders. 223, p. 1-7 7 p.

Research output: Contribution to journalArticle

MicroRNAs
Bipolar Disorder
Glutamic Acid
Oxidoreductases
Single Nucleotide Polymorphism
1 Citation (Scopus)

Factors affecting lumbar surgery outcome: A nation-wide, population-based retrospective study

Chin-Hung Chen, V., Yang, Y. H., Chen, P. Y., Yang, J. T., Chen, C. P. C., Chen, C. J., Lu, M. L., Lee, Y., McIntyre, R. S. & Huang, Y. C., Nov 1 2017, In : Journal of Affective Disorders. 222, p. 98-102 5 p.

Research output: Contribution to journalArticle

Analgesics
Retrospective Studies
Low Back Pain
Asthma
Anxiety

Methionine synthase 2756AA polymorphism is associated with the risk of cognitive impairment in patients with late-life depression

Yang, Y. H., Chiu, C. C., Teng, H. W., Chu, C. P., Chang, C. J., Chiu, W. C., Chen, C. H., Lu, M. L., Liu, S. I., Huang, S. Y., Liu, H. C. & Sun, I. W., Mar 1 2017, In : Asia-Pacific Psychiatry. 9, 1

Research output: Contribution to journalArticle

5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Apolipoprotein E4
Alleles
Depression
Genotype

The association between Mycoplasma pneumoniae infection and speech and language impairment: A nationwide population-based study in Taiwan

Tsai, C. S., Chen, V. C. H., Yang, Y. H., Hung, T. H., Lu, M. L., Huang, K. Y. & Gossop, M., Jul 1 2017, In : PLoS One. 12, 7, e0180402.

Research output: Contribution to journalArticle

Mycoplasma pneumoniae
Taiwan
Language
Hazards
Infection
2016
9 Citations (Scopus)

Application of plasma levels of olanzapine and N-desmethyl-olanzapine to monitor clinical efficacy in patients with schizophrenia

Lu, M. L., Wu, Y. X., Chen, C. H., Kuo, P. T., Chen, Y. H., Lin, C. H. & Wu, T. H., Feb 1 2016, In : PLoS One. 11, 2, e0148539.

Research output: Contribution to journalArticle

olanzapine
Schizophrenia
Plasmas
monitoring
dosage
2 Citations (Scopus)

Clinically significant interactions with antipsychotics

Lu, M. L. & Lane, H. Y., Jan 1 2016, Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents. Springer International Publishing, p. 397-421 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Antipsychotic Agents
Pharmacokinetics
Drug Interactions
Pharmaceutical Preparations
Social Adjustment
1 Citation (Scopus)

Effects of low dose metformin on metabolic traits in clozapine-treated schizophrenia patients: An exploratory twelve-week randomized, double-blind, placebo-controlled study

Chiu, C. C., Lu, M-L., Huang, M. C., Chen, P. Y., Lin, Y-K., Lin, S. K. & Chen, C-H., Dec 1 2016, In : PLoS One. 11, 12, e0168347.

Research output: Contribution to journalArticle

metformin
Clozapine
Metformin
placebos
Schizophrenia
2015
19 Citations (Scopus)

Differential effects of olanzapine and clozapine on plasma levels of adipocytokines and total ghrelin

Lu, M. L., Wang, T. N., Lin, T. Y., Shao, W. C., Chang, S. H., Chou, J. Y., Ho, Y. F., Liao, Y. T. & Chen, V. C. H., Apr 3 2015, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 58, p. 47-50 4 p.

Research output: Contribution to journalArticle

olanzapine
Ghrelin
Adipokines
Clozapine
Adiponectin
20 Citations (Scopus)

Investigation of associations between NR1D1, RORA and RORB genes and bipolar disorder

Lai, Y. C., Kao, C. F., Lu, M. L., Chen, H. C., Chen, P. Y., Chen, C. H., Shen, W. W., Wu, J. Y., Lu, R. B. & Kuo, P. H., Mar 19 2015, In : PLoS One. 10, 3, e0121245.

Research output: Contribution to journalArticle

Bipolar Disorder
Genes
genes
sampling
Association reactions
11 Citations (Scopus)

Ovarian cancer and antidepressants

Wu, C. S., Lu, M. L., Liao, Y. T., Lee, C. T. C. & Chen, V. C. H., May 1 2015, In : Psycho-Oncology. 24, 5, p. 579-584 6 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Antidepressive Agents
Logistic Models
National Health Programs
Taiwan
6 Citations (Scopus)

Survival analysis of the use of first and second generation antipsychotics among patients suffering schizophrenia: A nationwide population-based cohort study

Chen, V. C. H., Liao, Y. T., Lai, T. J., Lane, H. Y., Shao, W. C., Dewey, M., Lee, C. T. C. & Lu, M. L., Dec 1 2015, In : Schizophrenia Research. 169, 1-3, p. 406-411 6 p.

Research output: Contribution to journalArticle

Survival Analysis
Antipsychotic Agents
Schizophrenia
Cohort Studies
Population
2 Citations (Scopus)

The Relationships of Obesity-Related Genetic Variants with Metabolic Profiles and Response to Metformin in Clozapine-Treated Patients with Schizophrenia

Chen, P. Y., Lu, M. L., Huang, M. C., Kao, C. F., Kuo, P. H., Chiu, C. C., Lin, S. K. & Chen, C. H., Oct 12 2015, In : Journal of Clinical Psychopharmacology. 35, 5, p. 574-578 5 p.

Research output: Contribution to journalArticle

Metabolome
Clozapine
Metformin
Schizophrenia
Obesity
6 Citations (Scopus)

Tramadol-related psychosis in a patient with bipolar i disorder

Chen, K. J., Lu, M. L. & Shen, W. W., 2015, In : Acta Neuropsychiatrica. 27, 2, p. 126-128 3 p.

Research output: Contribution to journalArticle

Tramadol
Bipolar Disorder
Psychotic Disorders
Lithium
Delusions
2014
6 Citations (Scopus)

Hepatotoxicity induced by clozapine: A case report and review of literature

Wu Chou, A. I., Lu, M. L. & Shen, W. W., Aug 26 2014, In : Neuropsychiatric Disease and Treatment. 10, p. 1585-1587 3 p.

Research output: Contribution to journalArticle

Clozapine
Liver Function Tests
Acute Liver Failure
Liver
Transaminases
3 Citations (Scopus)

The genetic association of fto variants with metabolic traits in patients with schizophrenia may be modified by antipsychotics

Huang, M. C., Kao, C. F., Chiu, C. C., Kuo, P. H., Chen, P. Y., Lu, M. L. & Chen, C. H., Feb 2014, In : Journal of Clinical Psychopharmacology. 34, 1, p. 162-165 4 p.

Research output: Contribution to journalArticle

Schizophrenic Psychology
Genetic Predisposition to Disease
Antipsychotic Agents
Weight Gain
Blood Glucose
2013
15 Citations (Scopus)

CYP1A2 genetic polymorphisms are associated with early antidepressant escitalopram metabolism and adverse reactions

Kuo, H. W., Liu, S. C., Tsou, H. H., Liu, S. W., Lin, K. M., Lu, S. C., Hsiao, M. C., Hsiao, C. F., Liu, C. Y., Chen, C. H., Lu, M. L., Shen, W. W., Tang, H. S., Liu, S. I., Chang, L. H., Wu, H. Y., Chang, Y. S., Yeh, T. K., Chen, A. C. & Liu, Y. L., 2013, In : Pharmacogenomics. 14, 10, p. 1191-1201 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP1A2
Citalopram
Genetic Polymorphisms
Antidepressive Agents
Single Nucleotide Polymorphism
13 Citations (Scopus)
olanzapine
reversed-phase high performance liquid chromatography
High Pressure Liquid Chromatography
Plasmas
homocysteine
41 Citations (Scopus)
Clozapine
Metformin
Schizophrenia
Placebos
Body Weight
2012
23 Citations (Scopus)

Associations between n-3 PUFA concentrations and cognitive function after recovery from late-life depression

Chiu, C. C., Frangou, S., Chang, C. J., Chiu, W. C., Liu, H. C., Sun, I. W., Liu, S. I., Lu, M. L., Chen, C. H., Huang, S. Y., Dewey, M. E. & Stewart, R., Feb 1 2012, In : American Journal of Clinical Nutrition. 95, 2, p. 420-427 8 p.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Cognition
Depression
Erythrocyte Membrane
alpha-Linolenic Acid
17 Citations (Scopus)

Associations of polyunsaturated fatty acids with residual depression or anxiety in older people with major depression

Jadoon, A., Chiu, C. C., McDermott, L., Cunningham, P., Frangou, S., Chang, C. J., Sun, I. W., Liu, S. I., Lu, M. L., Su, K. P., Huang, S. Y. & Stewart, R., Feb 2012, In : Journal of Affective Disorders. 136, 3, p. 918-925 8 p.

Research output: Contribution to journalArticle

Unsaturated Fatty Acids
Anxiety
Depression
Omega-3 Fatty Acids
Linoleic Acid
2 Citations (Scopus)

Combined therapy with thioridazine decreases plasma levels of quetiapine in taiwanese schizophrenic patients

Chang, S. C., Lu, M. L., Wang, Y. C., Lin, F. W., Huang, S. H., Kuo, P. H., Ho, H. O. & Wu, T. H., Jun 2012, In : Therapeutic Drug Monitoring. 34, 3, p. 345-348 4 p.

Research output: Contribution to journalArticle

Thioridazine
Therapeutics
Schizophrenia
Quetiapine Fumarate
Pharmacokinetics
10 Citations (Scopus)

Metabolic and cardiovascular adverse effects associated with treatment with antipsychotic drugs

Chang, S. C. & Lu, M. L., Apr 2012, In : Journal of Experimental and Clinical Medicine(Taiwan). 4, 2, p. 103-107 5 p.

Research output: Contribution to journalArticle

Antipsychotic Agents
Weight Gain
Therapeutics
Serotonin
Cardiovascular Diseases
5 Citations (Scopus)

Pityriasis Rosea-like eruption associated with Clozapine: A case report

Lai, Y. W., Chou, C. Y., Shen, W. W. & Lu, M. L., Nov 2012, In : General Hospital Psychiatry. 34, 6

Research output: Contribution to journalArticle

Pityriasis Rosea
Clozapine
Drug-Related Side Effects and Adverse Reactions
Skin
Antipsychotic Agents
8 Citations (Scopus)

The relationship between serum uric acid concentration and metabolic syndrome in patients with schizophrenia or schizoaffective disorder

Chiu, C. C., Chen, C. H., Huang, M. C., Chen, P. Y., Tsai, C. J. & Lu, M. L., Oct 2012, In : Journal of Clinical Psychopharmacology. 32, 5, p. 585-592 8 p.

Research output: Contribution to journalArticle

Uric Acid
Psychotic Disorders
Schizophrenia
Serum
Social Adjustment