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Research Output 1986 2019

  • 3072 Citations
  • 30 h-Index
  • 164 Article
  • 1 Conference contribution
  • 1 Comment/debate
  • 1 Patent
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Article
2011
15 Citations (Scopus)

Pretreatment with an ethanolic extract of Taiwanofungus camphoratus (Antrodia camphorata) enhances the cytotoxic effects of amphotericin B

Chen, L. Y., Sheu, M. T., Liu, D. Z., Liao, C. K., Ho, H. O., Kao, W. Y., Ho, Y. S., Lee, W. S. & Su, C-H., Oct 26 2011, In : Journal of Agricultural and Food Chemistry. 59, 20, p. 11255-11263 9 p.

Research output: Contribution to journalArticle

Antrodia
Taiwanofungus camphoratus
amphotericin B
Amphotericin B
cytotoxicity
12 Citations (Scopus)

Rapid-onset sildenafil nasal spray carried by microemulsion systems: In vitro evaluation and in vivo pharmacokinetic studies in rabbits

Lu, H-T., Chen, R. N., Sheu, M. T., Chang, C. C., Chou, P. Y. & Ho, H. O., Jul 2011, In : Xenobiotica. 41, 7, p. 567-577 11 p.

Research output: Contribution to journalArticle

Nasal Sprays
Pharmacokinetics
Microemulsions
Polysorbates
Rabbits
2010
16 Citations (Scopus)

Anticancer Effects of Taiwanofungus camphoratus Extracts, Isolated Compounds and its Combinational use

Chen, Y. C., Ho, H. O., Su, C. H. & Sheu, M. T., Dec 2010, In : Journal of Experimental and Clinical Medicine(Taiwan). 2, 6, p. 274-281 8 p.

Research output: Contribution to journalArticle

Taiwan
trichostatin A
Succinates
Lovastatin
Agaricales
28 Citations (Scopus)

A quantitative structure - Activity relationship for the modulation effects of flavonoids on P-glycoprotein-mediated transport

Sheu, M. T., Liou, Y. B., Kao, Y. H., Lin, Y. K. & Ho, H. O., Sep 2010, In : Chemical and Pharmaceutical Bulletin. 58, 9, p. 1187-1194 8 p.

Research output: Contribution to journalArticle

Quantitative Structure-Activity Relationship
P-Glycoprotein
Flavonoids
Modulation
fexofenadine
16 Citations (Scopus)

Characterisation of fenofibrate dissolution delivered by a self-microemulsifying drug-delivery system

Wei, J. D., Ho, H. O., Chen, C. H., Ke, W. T., Chen, E. T. H. & Sheu, M. T., Dec 2010, In : Journal of Pharmacy and Pharmacology. 62, 12, p. 1685-1696 12 p.

Research output: Contribution to journalArticle

Fenofibrate
Drug Delivery Systems
Polysorbates
Water
Surface-Active Agents
41 Citations (Scopus)
Loratadine
Cyclodextrins
Curve fitting
Fourier Analysis
Fourier transforms
48 Citations (Scopus)
Carboxymethylcellulose Sodium
Losartan
Drug Delivery Systems
Cellulose
Healthy Volunteers
2 Citations (Scopus)
Chondrosarcoma
Glucosamine
Interleukin-1
Matrix Metalloproteinases
Facilitative Glucose Transport Proteins
4 Citations (Scopus)
Atmospheric Pressure
Ceramides
Liquid chromatography
Nude Mice
Liquid Chromatography
1 Citation (Scopus)

Self-microemulsifying premicroemulsion systems (SMEPMSs) as the template for preparing nanodrugs and Nanoparticles

Chen, Y. C., Huang, W. Y., Ho, H. O. & Sheu, M. T., Nov 2010, In : European Cells and Materials. 20, SUPPL.3, p. 40 1 p.

Research output: Contribution to journalArticle

Nanoparticles
2009
16 Citations (Scopus)

Construction of a quantitative structure-permeability relationship (QSPR) for the transdermal delivery of NSAIDs

Liou, Y. B., Ho, H. O., Yang, C. J., Lin, Y. K. & Sheu, M. T., Sep 15 2009, In : Journal of Controlled Release. 138, 3, p. 260-267 8 p.

Research output: Contribution to journalArticle

Permeability
Anti-Inflammatory Agents
Pharmaceutical Preparations
Skin
Elasticity
16 Citations (Scopus)
Citrus fruits
Fruit juices
Liquids
Water
Ficusin
31 Citations (Scopus)
Esomeprazole
Gastric Acid
Genotype
Pharmacokinetics
Cytochrome P-450 CYP2C19
13 Citations (Scopus)

TGF- βinhibits IL-1β-activated PAR-2 expression through multiple pathways in human primary synovial cells

Tsai, S. H., Sheu, M. T., Liang, Y. C., Cheng, H. T., Fang, S. S. & Chen, C. H., 2009, In : Journal of Biomedical Science. 16, 1, 97.

Research output: Contribution to journalArticle

PAR-2 Receptor
Interleukin-1
Connective Tissue Growth Factor
Osteoarthritis
Matrix Metalloproteinase 13
2008

Biotransformation of sildenafil in the male rat: Evaluation of drug interactions with testosterone and carbamazepine

Lin, Y. K., Sheu, M. T., Tzen, T. Z. & Ho, H. O., Nov 2008, In : Drug Development and Industrial Pharmacy. 34, 11, p. 1219-1226 8 p.

Research output: Contribution to journalArticle

Drug interactions
Carbamazepine
Biotransformation
Drug Interactions
Testosterone
19 Citations (Scopus)

Chondroprotective effects of glucosamine involving the p38 MAPK and Akt signaling pathways

Lin, Y. C., Liang, Y. C., Sheu, M. T., Lin, Y. C., Hsieh, M-S., Chen, T-F. & Chen, C. H., Aug 2008, In : Rheumatology International. 28, 10, p. 1009-1016 8 p.

Research output: Contribution to journalArticle

Glucosamine
p38 Mitogen-Activated Protein Kinases
Interleukin-1
Matrix Metalloproteinase 3
Transcription Factor AP-1
13 Citations (Scopus)
Glucosamine
Metalloproteases
Fibroblasts
Matrix Metalloproteinases
Interleukin-1
Dextromethorphan
Metabolites
Silicon Dioxide
Dextrorphan
Amines
6 Citations (Scopus)

Process and formulation characterizations of the thermal adhesion granulation (TAG) process for improving granular properties

Lin, H. L., Ho, H. O., Chen, C. C., Yeh, T. S. & Sheu, M. T., Jun 5 2008, In : International Journal of Pharmaceutics. 357, 1-2, p. 206-212 7 p.

Research output: Contribution to journalArticle

Polyvinyls
Pyrrolidinones
Hot Temperature
Excipients
Ethanol
19 Citations (Scopus)
Osmotic Pressure
Drug Delivery Systems
Tablets
Rupture
Membranes
11 Citations (Scopus)

SP1-regulated p27/Kip1 gene expression is involved in terbinafine-induced human A431 cancer cell differentiation: An in vitro and in vivo study

Huang, C. S., Ho, W. L., Lee, W. S., Sheu, M. T., Wang, Y. J., Tu, S. H., Chen, R. J., Chu, J. S., Chen, L. C., Lee, C. H., Tseng, H., Ho, Y. S. & Wu, C. H., May 1 2008, In : Biochemical Pharmacology. 75, 9, p. 1783-1796 14 p.

Research output: Contribution to journalArticle

terbinafine
Gene expression
Tumors
Cell Differentiation
Cells
8 Citations (Scopus)

Structure and anti-proliferation function of 5,5-diphenyl-2-thiohydantoin (DPTH) derivatives in vascular endothelial cells

Cheng, C. K., Wu, J., Liu, Y., Lee, T. S., Kang, S. J., Sheu, M. T. & Lee, W. S., Feb 2008, In : Vascular Pharmacology. 48, 2-3, p. 138-142 5 p.

Research output: Contribution to journalArticle

Umbilicus
Endothelial Cells
Phenytoin
Cell Cycle
Cyclin-Dependent Kinase 2
2007
6 Citations (Scopus)

Intra-articular injection of hyaluronate and indomethacin in rabbits with antigen-induced arthritis

Lo, Y. J., Sheu, M. T., Tsai, W. C., Lin, Y. H., Li, J. L., Liang, Y. C., Chang, C. C., Hsieh, M-S. & Chen, C. H., Oct 2007, In : Rheumatology International. 27, 12, p. 1099-1111 13 p.

Research output: Contribution to journalArticle

Intra-Articular Injections
Matrix Metalloproteinase 3
Indomethacin
C-Reactive Protein
Arthritis
34 Citations (Scopus)

Release characteristics of lidocaine from local implant of polyanionic and polycationic hydrogels

Liu, D. Z., Sheu, M. T., Chen, C. H., Yang, Y. R. & Ho, H. O., Apr 23 2007, In : Journal of Controlled Release. 118, 3, p. 333-339 7 p.

Research output: Contribution to journalArticle

Hydrogels
Lidocaine
Chitosan
Hydrogel
Salts
27 Citations (Scopus)
Dextromethorphan
Plasma (human)
Metabolites
Dextrorphan
High Pressure Liquid Chromatography
2006
140 Citations (Scopus)

Development of N,O-(carboxymethyl)chitosan/collagen matrixes as a wound dressing

Chen, R. N., Wang, G. M., Chen, C. H., Ho, H. O. & Sheu, M. T., Apr 2006, In : Biomacromolecules. 7, 4, p. 1058-1064 7 p.

Research output: Contribution to journalArticle

Bandages
Chitosan
Collagen
Acellular Dermis
Wounds and Injuries
4 Citations (Scopus)

Drug release from hydroxypropyl cellulose and polyethylene oxide capsules: In vitro and in vivo assessment

Lee, C. Y., Chen, G. L., Sheu, M. T. & Liu, C. H., Feb 2006, In : Chinese Pharmaceutical Journal. 58, 1, p. 57-65 9 p.

Research output: Contribution to journalArticle

Polyethylene oxides
Capsules
Cellulose
Pharmaceutical Preparations
Pharmacokinetics
8 Citations (Scopus)
Minoxidil
Succinic Acid
Ethanol
Water
Solubility
10 Citations (Scopus)

Novel design of osmotic chitosan capsules characterized by asymmetric membrane structure for in situ formation of delivery orifice

Wang, G. M., Chen, C. H., Ho, H. O., Wang, S. S. & Sheu, M. T., Aug 17 2006, In : International Journal of Pharmaceutics. 319, 1-2, p. 71-81 11 p.

Research output: Contribution to journalArticle

Chitosan
Capsules
Membranes
Sodium Dodecyl Sulfate
Felodipine

Physical characterization and drug release profiling for hard capsules prepared with hydroxypropylcellulose or polyethylene oxide

Lee, C. Y., Chen, G. L., Sheu, M. T. & Liu, C. H., Apr 2006, In : Chinese Pharmaceutical Journal. 58, 2-6, p. 75-84 10 p.

Research output: Contribution to journalArticle

Polyethylene oxides
Capsules
Dissolution
Salts
Pharmaceutical Preparations
88 Citations (Scopus)

Suppression of endotoxin-induced proinflammatory responses by citrus pectin through blocking LPS signaling pathways

Chen, C. H., Sheu, M. T., Chen, T-F., Wang, Y. C., Hou, W. C., Liu, D. Z., Chung, T-C. & Liang, Y. C., Oct 16 2006, In : Biochemical Pharmacology. 72, 8, p. 1001-1009 9 p.

Research output: Contribution to journalArticle

Endotoxins
Lipopolysaccharides
Nitric Oxide Synthase Type II
Cyclooxygenase 2
Macrophages
2005
43 Citations (Scopus)

Asymmetric membrane capsules for delivery of poorly water-soluble drugs by osmotic effects

Wang, C. Y., Ho, H. O., Lin, L. H., Lin, Y. K. & Sheu, M. T., Jun 13 2005, In : International Journal of Pharmaceutics. 297, 1-2, p. 89-97 9 p.

Research output: Contribution to journalArticle

Capsules
Felodipine
Sodium Dodecyl Sulfate
Nifedipine
Membranes
81 Citations (Scopus)

Characterization of collagen matrices crosslinked using microbial transglutaminase

Chen, R. N., Ho, H. O. & Sheu, M. T., Jul 2005, In : Biomaterials. 26, 20, p. 4229-4235 7 p.

Research output: Contribution to journalArticle

Transglutaminases
Collagen
Crosslinking
Cross-Linking Reagents
Denaturation
31 Citations (Scopus)

Characterization of cortical neuron outgrowth in two- and three-dimensional culture systems

Lin, P. W., Wu, C-C., Chen, C. H., Ho, H. O., Chen, Y. C. & Sheu, M. T., Oct 2005, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 75, 1, p. 146-157 12 p.

Research output: Contribution to journalArticle

Collagen
Neurons
Biocompatible Materials
Fibrin
Biomaterials
6 Citations (Scopus)
Artificial Skin
Matrix Metalloproteinases
Skin
Membranes
Tissue
68 Citations (Scopus)
Succinic Acid
Surface-Active Agents
Polysorbates
Pharmaceutical Preparations
Proteins
11 Citations (Scopus)
Minoxidil
Hair
Growth
Sulfotransferases
poly(ethylene succinate)
2004
12 Citations (Scopus)
Endothelial cells
Cell Cycle Checkpoints
Endothelial Cells
Cells
Cyclin-Dependent Kinase 2
14 Citations (Scopus)

Anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH) in human vascular endothelial cells

Shih, C. R., Wu, J., Liu, Y., Liang, Y. C., Lin, S. Y., Sheu, M. T. & Lee, W. S., Jan 1 2004, In : Biochemical Pharmacology. 67, 1, p. 67-75 9 p.

Research output: Contribution to journalArticle

Endothelial cells
Human Umbilical Vein Endothelial Cells
Endothelial Cells
Phosphotransferases
Thymidine
7 Citations (Scopus)
Silicon Dioxide
Acetic Acid
Liquids
Ionization
Ion Exchange
3 Citations (Scopus)

Photolysis of NSAIDs. Part 3: Structural elucidation of photoproducts of tolmetin in methanol

Sheu, M. T., Wu, J., Chen, C. J., Chao, S. H. & Wu, A-B., Oct 18 2004, In : Tetrahedron Letters. 45, 43, p. 8107-8109 3 p.

Research output: Contribution to journalArticle

Tolmetin
Photolysis
Non-Steroidal Anti-Inflammatory Agents
Methanol
Decarboxylation
154 Citations (Scopus)

Process development of an acellular dermal matrix (ADM) for biomedical applications

Chen, R. N., Ho, H. O., Tsai, Y. T. & Sheu, M. T., Jun 2004, In : Biomaterials. 25, 13, p. 2679-2686 8 p.

Research output: Contribution to journalArticle

Acellular Dermis
Collagen
Skin
Sodium dodecyl sulfate
Sodium Dodecyl Sulfate
24 Citations (Scopus)

Production of the chemokine eotaxin-1 in osteoarthritis and its role in cartilage degradation

Hsu, Y. H., Hsieh, M-S., Liang, Y. C., Li, C. Y., Sheu, M. T., Chou, D. T., Chen, T-F. & Chen, C. H., 2004, In : Journal of Cellular Biochemistry. 93, 5, p. 929-939 11 p.

Research output: Contribution to journalArticle

Chemokine CCL11
Cartilage
Chemokines
Osteoarthritis
Degradation
4 Citations (Scopus)

Viscoelastic characterizations of acellular dermal matrix (ADM) preparations for use as injectable implants

Ho, H. O., Tsai, Y. T., Chen, R. N. & Sheu, M. T., Jul 1 2004, In : Journal of Biomedical Materials Research - Part A. 70, 1, p. 83-96 14 p.

Research output: Contribution to journalArticle

Glutaral
glycolic acid
Elastic moduli
Hyaluronic acid
Acids
2003
18 Citations (Scopus)

Analysis of pharmacokinetic parameters for assessment of dextromethorphan metabolic phenotypes

Yeh, G. C., Tao, P. L., Ho, H. O., Lee, Y. J., Chen, Y-R. & Sheu, M. T., 2003, In : Journal of Biomedical Science. 10, 5, p. 552-564 13 p.

Research output: Contribution to journalArticle

Dextromethorphan
Pharmacokinetics
Phenotype
Caves
Plasmas
11 Citations (Scopus)

Correlation of in vivo and in vitro measurements of sun protection factor

Sheu, M. T., Lin, C. W., Huang, M. C., Shen, C. H. & Ho, H. O., Jun 2003, In : Journal of Food and Drug Analysis. 11, 2, p. 128-132 5 p.

Research output: Contribution to journalArticle

Sun Protection Factor
Sunscreening Agents
testing
transmittance
Xenon
48 Citations (Scopus)
Liquids
High Pressure Liquid Chromatography
Plasmas
Healthy Volunteers
Biological Availability
52 Citations (Scopus)
Micelles
Solubility
Estradiol
Alcohols
poly(ethylene succinate)
10 Citations (Scopus)

Photolysis of NSAIDS. I. Photodegradation products of carprofen determined by LC-ESI-MS

Sheu, M. T., Ho, H. O., Wang, P. Y., Liou, Y. B. & Wu, A-B., Apr 2003, In : Journal of Chromatographic Science. 41, 4, p. 200-204 5 p.

Research output: Contribution to journalArticle

Electrospray ionization
Electrospray Ionization Mass Spectrometry
Photolysis
Liquid chromatography
Photodegradation