• 3267 Citations
  • 32 h-Index
1986 …2020

Research output per year

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Research Output

  • 3267 Citations
  • 32 h-Index
  • 167 Article
  • 2 Comment/debate
  • 1 Conference contribution
  • 1 Patent
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Article
2012

Wound-healing effect of micronized sacchachitin (mSC) nanogel on corneal epithelium

Chen, R. N., Lee, L. W., Chen, L. C., Ho, H. O., Lui, S. C., Sheu, M. T. & Su, C-H., 2012, In : International Journal of Nanomedicine. 7, p. 4697-4706 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2011

Anti-Inflammatory mechanisms of the proteinase-activated receptor 2-inhibiting peptide in human synovial cells

Chen, T-L., Lin, Y-F., Cheng, C-W., Chen, S. Y., Sheu, M-T., Leung, T-K., Qin, C. H. & Chen, C-H., 2011, In : Journal of Biomedical Science. 18, 1, 43.

Research output: Contribution to journalArticle

4 Citations (Scopus)

In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate.

Lin, Y. M., Wu, J. Y., Chen, Y. C., Su, Y. D., Ke, W. T., Ho, H. O. & Sheu, M. T., 2011, In : International Journal of Nanomedicine. 6, p. 2445-2457 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Pretreatment with an ethanolic extract of Taiwanofungus camphoratus (Antrodia camphorata) enhances the cytotoxic effects of amphotericin B

Chen, L. Y., Sheu, M. T., Liu, D. Z., Liao, C. K., Ho, H. O., Kao, W. Y., Ho, Y. S., Lee, W. S. & Su, C-H., Oct 26 2011, In : Journal of Agricultural and Food Chemistry. 59, 20, p. 11255-11263 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Rapid-onset sildenafil nasal spray carried by microemulsion systems: In vitro evaluation and in vivo pharmacokinetic studies in rabbits

Lu, H-T., Chen, R. N., Sheu, M. T., Chang, C. C., Chou, P. Y. & Ho, H. O., Jul 2011, In : Xenobiotica. 41, 7, p. 567-577 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2010

Anticancer Effects of Taiwanofungus camphoratus Extracts, Isolated Compounds and its Combinational use

Chen, Y. C., Ho, H. O., Su, C. H. & Sheu, M. T., Dec 2010, In : Journal of Experimental and Clinical Medicine(Taiwan). 2, 6, p. 274-281 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A quantitative structure - Activity relationship for the modulation effects of flavonoids on P-glycoprotein-mediated transport

Sheu, M. T., Liou, Y. B., Kao, Y. H., Lin, Y. K. & Ho, H. O., Sep 2010, In : Chemical and Pharmaceutical Bulletin. 58, 9, p. 1187-1194 8 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Characterisation of fenofibrate dissolution delivered by a self-microemulsifying drug-delivery system

Wei, J. D., Ho, H. O., Chen, C. H., Ke, W. T., Chen, E. T. H. & Sheu, M. T., Dec 2010, In : Journal of Pharmacy and Pharmacology. 62, 12, p. 1685-1696 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
41 Citations (Scopus)
50 Citations (Scopus)
2 Citations (Scopus)
5 Citations (Scopus)

Self-microemulsifying premicroemulsion systems (SMEPMSs) as the template for preparing nanodrugs and Nanoparticles

Chen, Y. C., Huang, W. Y., Ho, H. O. & Sheu, M. T., Nov 2010, In : European Cells and Materials. 20, SUPPL.3, p. 40 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2009

Construction of a quantitative structure-permeability relationship (QSPR) for the transdermal delivery of NSAIDs

Liou, Y. B., Ho, H. O., Yang, C. J., Lin, Y. K. & Sheu, M. T., Sep 15 2009, In : Journal of Controlled Release. 138, 3, p. 260-267 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
17 Citations (Scopus)
32 Citations (Scopus)

TGF- βinhibits IL-1β-activated PAR-2 expression through multiple pathways in human primary synovial cells

Tsai, S. H., Sheu, M. T., Liang, Y. C., Cheng, H. T., Fang, S. S. & Chen, C. H., 2009, In : Journal of Biomedical Science. 16, 1, 97.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2008

Biotransformation of sildenafil in the male rat: Evaluation of drug interactions with testosterone and carbamazepine

Lin, Y. K., Sheu, M. T., Tzen, T. Z. & Ho, H. O., Nov 2008, In : Drug Development and Industrial Pharmacy. 34, 11, p. 1219-1226 8 p.

Research output: Contribution to journalArticle

Chondroprotective effects of glucosamine involving the p38 MAPK and Akt signaling pathways

Lin, Y. C., Liang, Y. C., Sheu, M. T., Lin, Y. C., Hsieh, M-S., Chen, T-F. & Chen, C. H., Aug 2008, In : Rheumatology International. 28, 10, p. 1009-1016 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
14 Citations (Scopus)

Process and formulation characterizations of the thermal adhesion granulation (TAG) process for improving granular properties

Lin, H. L., Ho, H. O., Chen, C. C., Yeh, T. S. & Sheu, M. T., Jun 5 2008, In : International Journal of Pharmaceutics. 357, 1-2, p. 206-212 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
19 Citations (Scopus)

SP1-regulated p27/Kip1 gene expression is involved in terbinafine-induced human A431 cancer cell differentiation: An in vitro and in vivo study

Huang, C. S., Ho, W. L., Lee, W. S., Sheu, M. T., Wang, Y. J., Tu, S. H., Chen, R. J., Chu, J. S., Chen, L. C., Lee, C. H., Tseng, H., Ho, Y. S. & Wu, C. H., May 1 2008, In : Biochemical Pharmacology. 75, 9, p. 1783-1796 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Structure and anti-proliferation function of 5,5-diphenyl-2-thiohydantoin (DPTH) derivatives in vascular endothelial cells

Cheng, C. K., Wu, J., Liu, Y., Lee, T. S., Kang, S. J., Sheu, M. T. & Lee, W. S., Feb 2008, In : Vascular Pharmacology. 48, 2-3, p. 138-142 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2007

Intra-articular injection of hyaluronate and indomethacin in rabbits with antigen-induced arthritis

Lo, Y. J., Sheu, M. T., Tsai, W. C., Lin, Y. H., Li, J. L., Liang, Y. C., Chang, C. C., Hsieh, M-S. & Chen, C. H., Oct 2007, In : Rheumatology International. 27, 12, p. 1099-1111 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Release characteristics of lidocaine from local implant of polyanionic and polycationic hydrogels

Liu, D. Z., Sheu, M. T., Chen, C. H., Yang, Y. R. & Ho, H. O., Apr 23 2007, In : Journal of Controlled Release. 118, 3, p. 333-339 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
28 Citations (Scopus)
2006

Development of N,O-(carboxymethyl)chitosan/collagen matrixes as a wound dressing

Chen, R. N., Wang, G. M., Chen, C. H., Ho, H. O. & Sheu, M. T., Apr 2006, In : Biomacromolecules. 7, 4, p. 1058-1064 7 p.

Research output: Contribution to journalArticle

144 Citations (Scopus)

Drug release from hydroxypropyl cellulose and polyethylene oxide capsules: In vitro and in vivo assessment

Lee, C. Y., Chen, G. L., Sheu, M. T. & Liu, C. H., Feb 2006, In : Chinese Pharmaceutical Journal. 58, 1, p. 57-65 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
8 Citations (Scopus)

Novel design of osmotic chitosan capsules characterized by asymmetric membrane structure for in situ formation of delivery orifice

Wang, G. M., Chen, C. H., Ho, H. O., Wang, S. S. & Sheu, M. T., Aug 17 2006, In : International Journal of Pharmaceutics. 319, 1-2, p. 71-81 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Physical characterization and drug release profiling for hard capsules prepared with hydroxypropylcellulose or polyethylene oxide

Lee, C. Y., Chen, G. L., Sheu, M. T. & Liu, C. H., Apr 2006, In : Chinese Pharmaceutical Journal. 58, 2-6, p. 75-84 10 p.

Research output: Contribution to journalArticle

Suppression of endotoxin-induced proinflammatory responses by citrus pectin through blocking LPS signaling pathways

Chen, C. H., Sheu, M. T., Chen, T-F., Wang, Y. C., Hou, W. C., Liu, D. Z., Chung, T-C. & Liang, Y. C., Oct 16 2006, In : Biochemical Pharmacology. 72, 8, p. 1001-1009 9 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)
2005

Asymmetric membrane capsules for delivery of poorly water-soluble drugs by osmotic effects

Wang, C. Y., Ho, H. O., Lin, L. H., Lin, Y. K. & Sheu, M. T., Jun 13 2005, In : International Journal of Pharmaceutics. 297, 1-2, p. 89-97 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Characterization of collagen matrices crosslinked using microbial transglutaminase

Chen, R. N., Ho, H. O. & Sheu, M. T., Jul 2005, In : Biomaterials. 26, 20, p. 4229-4235 7 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Characterization of cortical neuron outgrowth in two- and three-dimensional culture systems

Lin, P. W., Wu, C-C., Chen, C. H., Ho, H. O., Chen, Y. C. & Sheu, M. T., Oct 2005, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 75, 1, p. 146-157 12 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
11 Citations (Scopus)
71 Citations (Scopus)
12 Citations (Scopus)
2004
12 Citations (Scopus)

Anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH) in human vascular endothelial cells

Shih, C. R., Wu, J., Liu, Y., Liang, Y. C., Lin, S. Y., Sheu, M. T. & Lee, W. S., Jan 1 2004, In : Biochemical Pharmacology. 67, 1, p. 67-75 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
7 Citations (Scopus)

Photolysis of NSAIDs. Part 3: Structural elucidation of photoproducts of tolmetin in methanol

Sheu, M. T., Wu, J., Chen, C. J., Chao, S. H. & Wu, A-B., Oct 18 2004, In : Tetrahedron Letters. 45, 43, p. 8107-8109 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Process development of an acellular dermal matrix (ADM) for biomedical applications

Chen, R. N., Ho, H. O., Tsai, Y. T. & Sheu, M. T., Jun 2004, In : Biomaterials. 25, 13, p. 2679-2686 8 p.

Research output: Contribution to journalArticle

168 Citations (Scopus)

Production of the chemokine eotaxin-1 in osteoarthritis and its role in cartilage degradation

Hsu, Y. H., Hsieh, M-S., Liang, Y. C., Li, C. Y., Sheu, M. T., Chou, D. T., Chen, T-F. & Chen, C. H., 2004, In : Journal of Cellular Biochemistry. 93, 5, p. 929-939 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Viscoelastic characterizations of acellular dermal matrix (ADM) preparations for use as injectable implants

Ho, H. O., Tsai, Y. T., Chen, R. N. & Sheu, M. T., Jul 1 2004, In : Journal of Biomedical Materials Research - Part A. 70, 1, p. 83-96 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2003

Analysis of pharmacokinetic parameters for assessment of dextromethorphan metabolic phenotypes

Yeh, G. C., Tao, P. L., Ho, H. O., Lee, Y. J., Chen, Y-R. & Sheu, M. T., 2003, In : Journal of Biomedical Science. 10, 5, p. 552-564 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Correlation of in vivo and in vitro measurements of sun protection factor

Sheu, M. T., Lin, C. W., Huang, M. C., Shen, C. H. & Ho, H. O., Jun 2003, In : Journal of Food and Drug Analysis. 11, 2, p. 128-132 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)