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Research Output 1986 2019

  • 3127 Citations
  • 30 h-Index
  • 164 Article
  • 1 Conference contribution
  • 1 Comment/debate
  • 1 Patent
2019
2 Citations (Scopus)

Development of Decellularized Cornea by Organic Acid Treatment for Corneal Regeneration

Lin, H. J., Wang, T. J., Li, T. W., Chang, Y. Y., Sheu, M. T., Huang, Y. Y. & Liu, D. Z., Apr 1 2019, In : Tissue Engineering - Part A. 25, 7-8, p. 652-662 11 p.

Research output: Contribution to journalArticle

Organic acids
Scaffolds
Cornea
Regeneration
Swine
2 Citations (Scopus)

In situ chemically crosslinked injectable hydrogels for the subcutaneous delivery of trastuzumab to treat breast cancer

Lo, Y. W., Sheu, M. T., Chiang, W. H., Chiu, Y. L., Tu, C. M., Wang, W. Y., Wu, M. H., Wang, Y. C., Lu, M. & Ho, H. O., Mar 1 2019, In : Acta Biomaterialia. 86, p. 280-290 11 p.

Research output: Contribution to journalArticle

Hydrogels
Hydrogel
Breast Neoplasms
Injections
Antibodies
2018
4 Citations (Scopus)
docetaxel
Bispecific Antibodies
Lecithins
Drug Delivery Systems
Neoplasms
3 Citations (Scopus)
10 Citations (Scopus)
docetaxel
Lecithins
Drug Delivery Systems
Therapeutics
Neoplasms
docetaxel
Ultrafiltration
Pharmacokinetics
1 Citation (Scopus)
Lecithins
Quercetin
Micelles
Therapeutic Uses
Doxorubicin
2 Citations (Scopus)

Measurement of solid solubility of warfarin in supercritical carbon dioxide and recrystallization study using supercritical antisolvent process

Ciou, J. M., Wang, B. C., Su, C. S., Liu, J. J. & Sheu, M. T., Jan 1 2018, (Accepted/In press) In : Advanced Powder Technology.

Research output: Contribution to journalArticle

Warfarin
Carbon Dioxide
Carbon dioxide
Solubility
Flow rate
6 Citations (Scopus)
docetaxel
Poloxamer
Lecithins
Ovarian Neoplasms
Cisplatin
4 Citations (Scopus)
Clustered Regularly Interspaced Short Palindromic Repeats
Polyethyleneimine
Cell death
Serum Albumin
Immunotherapy
2017
3 Citations (Scopus)

Application of two-level factorial design to investigate the effect of process parameters on the sonocrystallization of sulfathiazole

Kuo, P. H., Zhang, B. C., Su, C. S., Liu, J. J. & Sheu, M. T., Aug 1 2017, In : Journal of Crystal Growth. 471, p. 8-14 7 p.

Research output: Contribution to journalArticle

factorial design
Sonication
habits
solid state
analysis of variance
2 Citations (Scopus)
docetaxel
Pharmacokinetics
Ultrafiltration
Plasmas
Micelles
5 Citations (Scopus)

Physical and Pharmacokinetic Characterizations of trans-Resveratrol (t-Rev) Encapsulated with Self-Assembling Lecithin-based Mixed Polymeric Micelles (saLMPMs)

Li, T. P., Wong, W. P., Chen, L. C., Su, C. Y., Chen, L. G., Liu, D. Z., Ho, H. O. & Sheu, M. T., Dec 1 2017, In : Scientific Reports. 7, 1, 10674.

Research output: Contribution to journalArticle

Lecithins
Micelles
Pharmacokinetics
Biological Availability
resveratrol
19 Citations (Scopus)

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for in Vivo Gene Silencing in Leukemia

Lee, D. J., Kessel, E., Lehto, T., Liu, X., Yoshinaga, N., Padari, K., Chen, Y. C., Kempter, S., Uchida, S., Rädler, J. O., Pooga, M., Sheu, M. T., Kataoka, K. & Wagner, E., Sep 20 2017, In : Bioconjugate Chemistry. 28, 9, p. 2393-2409 17 p.

Research output: Contribution to journalArticle

Gene Silencing
RNA
Small Interfering RNA
Polyethylene glycols
Leukemia
2016
24 Citations (Scopus)

Codelivery of doxorubicin-containing thermosensitive hydrogels incorporated with docetaxel-loaded mixed micelles enhances local cancer therapy

Sheu, M. T., Jhan, H. J., Su, C. Y., Chen, L. C., Chang, C. E., Liu, D. Z. & Ho, H. O., Jul 1 2016, In : Colloids and Surfaces B: Biointerfaces. 143, p. 260-270 11 p.

Research output: Contribution to journalArticle

docetaxel
Hydrogels
Micelles
Doxorubicin
Tumors
11 Citations (Scopus)

Development and Characterization of Lecithin-based Self-assembling Mixed Polymeric Micellar (saMPMs) Drug Delivery Systems for Curcumin

Chen, L. C., Chen, Y-C., Su, C. Y., Wong, W. P., Sheu, M-T. & Ho, H-O., Nov 16 2016, In : Scientific Reports. 6, 37122.

Research output: Contribution to journalArticle

Curcumin
Lecithins
Drug Delivery Systems
Micelles
Biological Availability
16 Citations (Scopus)
Lecithin
Pharmacokinetics
Oncology
Lecithins
Quercetin
12 Citations (Scopus)

Improving the stability of astaxanthin by microencapsulation in calcium alginate beads

Lin, S. F., Chen, Y. C., Chen, R. N., Chen, L. C., Ho, H. O., Tsung, Y. H., Sheu, M. T. & Liu, D. Z., Apr 1 2016, In : PLoS One. 11, 4, e0153685.

Research output: Contribution to journalArticle

Microencapsulation
calcium alginate
microencapsulation
Drug Compounding
astaxanthin
16 Citations (Scopus)
Platelet-Rich Plasma
Recovery of Function
Platelets
Rats
Plasmas
5 Citations (Scopus)

Rapid-Onset Sildenafil Sublingual Drug Delivery Systems: In Vitro Evaluation and In Vivo Pharmacokinetic Studies in Rabbits

Sheu, M. T., Hsieh, C. M., Chen, R. N., Chou, P. Y. & Ho, H. O., Sep 1 2016, In : Journal of Pharmaceutical Sciences. 105, 9, p. 2774-2781 8 p.

Research output: Contribution to journalArticle

Drug Delivery Systems
Pharmacokinetics
Rabbits
Propylene Glycol
Polymethyl Methacrylate
4 Downloads (Pure)

Thermosenstive injectable hydrogel for drug delivery

Jhan, H. J., Ho, H-O., Sheu, M-T., Shen, S-C., Ho, Y-S. & Liu, J-J., Jun 14 2016, Patent No. US 9,364,545 B2 , Jun 19 2014, Priority date Jun 19 2014

Research output: Patent

Hydrogel
Patents and inventions
Drug delivery
Polypropylene oxides
Copolymers
2015
38 Citations (Scopus)

Development and Characterization of Acellular Extracellular Matrix Scaffolds from Porcine Menisci for Use in Cartilage Tissue Engineering

Chen, Y. C., Chen, R. N., Jhan, H. J., Liu, D. Z., Ho, H. O., Mao, Y., Kohn, J. & Sheu, M. T., Sep 1 2015, In : Tissue Engineering - Part C: Methods. 21, 9, p. 971-986 16 p.

Research output: Contribution to journalArticle

Cartilage
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Scaffolds
24 Citations (Scopus)
Antrodia
Complementary Therapies
Doxorubicin
Curcumin
Antioxidants
7 Citations (Scopus)

Formulation and process optimization of multiparticulate pulsatile system delivered by osmotic pressure-activated rupturable membrane

Hung, S. F., Hsieh, C. M., Chen, Y. C., Lin, C. M., Ho, H. O. & Sheu, M. T., Mar 1 2015, In : International Journal of Pharmaceutics. 480, 1-2, p. 15-26 12 p.

Research output: Contribution to journalArticle

Osmotic Pressure
Omeprazole
Solubility
Membranes
Propranolol
1 Citation (Scopus)

Mycelial mattress from a sporangia formation-delayed mutant of Rhizopus stoloniferas wound healing-enhancing biomaterial

Chien, M. Y., Chen, L. C., Chen, Y. C., Sheu, M. T., Tsai, Y. C., Ho, H. O., Su, C. H. & Liu, D. Z., Aug 14 2015, In : PLoS One. 10, 8, e0134090.

Research output: Contribution to journalArticle

Sporangia
Rhizopus
Trifluoroacetic Acid
Sodium Hydroxide
biocompatible materials
17 Citations (Scopus)

Novel injectable thermosensitive hydrogels for delivering hyaluronic acid-doxorubicin nanocomplexes to locally treat tumors

Jhan, H. J., Liu, J. J., Chen, Y. C., Liu, D. Z., Sheu, M. T. & Ho, H. O., Apr 1 2015, In : Nanomedicine. 10, 8, p. 1263-1274 12 p.

Research output: Contribution to journalArticle

Hyaluronic acid
Hydrogels
Hyaluronic Acid
tumor
Doxorubicin
14 Citations (Scopus)

Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles

Chen, Y. C., Su, C. Y., Jhan, H. J., Ho, H. O. & Sheu, M. T., Dec 2 2015, In : International Journal of Nanomedicine. 10, p. 7265-7274 10 p.

Research output: Contribution to journalArticle

Lecithin
Pharmacokinetics
Lecithins
Micelles
Amphotericin B
8 Citations (Scopus)
dissolving
Dissolution
solid state
habits
acids
14 Citations (Scopus)
drug delivery systems
Carboxymethylcellulose Sodium
carboxymethylcellulose
Drug Delivery Systems
Cellulose
2014
9 Citations (Scopus)
Chemical modification
Hyaluronic Acid
Oral Administration
Molecular Weight
Molecular weight
10 Citations (Scopus)
drug delivery systems
Drug Delivery Systems
Polymer films
films (materials)
Plasticizers
5 Citations (Scopus)

Dried fruit of the Luffa sponge as a source of chitin for applications as skin substitutes

Jiang, P. L., Chien, M. Y., Sheu, M. T., Huang, Y. Y., Chen, M. H., Su, C-H. & Liu, D. Z., 2014, In : BioMed Research International. 2014, 458287.

Research output: Contribution to journalArticle

Luffa
Artificial Skin
Chitin
Porifera
Fruits
11 Citations (Scopus)
Vitamin E
Hot Temperature
Hardness
Excipients
Pharmaceutical Preparations
2013
39 Citations (Scopus)

Analysis of the enhanced oral bioavailability of fenofibrate lipid formulations in fasted humans using an in vitro-in silico-in vivo approach

Fei, Y., Kostewicz, E. S., Sheu, M. T. & Dressman, J. B., Nov 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 PART B, p. 1274-1284 11 p.

Research output: Contribution to journalArticle

Fenofibrate
Computer Simulation
Biological Availability
Drug Delivery Systems
Lipids
7 Citations (Scopus)
Alendronate
Dosage Forms
Chitosan
Cellulose
Tablets
2 Citations (Scopus)
Freeze Drying
Drying
Fenofibrate
Water
Particle Size
Chronotherapy
propranolol
Propranolol
pellets
extrusion
17 Citations (Scopus)

Injectable hyaluronic-acid-doxycycline hydrogel therapy in experimental rabbit osteoarthritis

Lu, H-T., Sheu, M. T., Lin, Y. F., Lan, J., Chin, Y. P., Hsieh, M-S., Cheng, C. W. & Chen, C. H., Apr 10 2013, In : BMC Veterinary Research. 9, 68.

Research output: Contribution to journalArticle

hyaluronic acid
Investigational Therapies
doxycycline
Doxycycline
Hydrogel
29 Citations (Scopus)
Chitosan
Drug Delivery Systems
Sodium Bicarbonate
Losartan
Viscosity
8 Citations (Scopus)

Taiwanofungus camphoratus (Syn Antrodia camphorata) extract and amphotericin B exert adjuvant effects via mitochondrial apoptotic pathway

Chen, L. Y., Sheu, M. T., Liao, C. K., Tsai, F-C., Kao, W. Y. & Su, C-H., Mar 2013, In : Integrative Cancer Therapies. 12, 2, p. 153-164 12 p.

Research output: Contribution to journalArticle

Antrodia
Amphotericin B
Apoptosis Regulatory Proteins
Cell Line
Neoplasms
2012
Glycerophospholipids
sphingolipids
Sphingolipids
Electrospray Ionization Mass Spectrometry
cerebrospinal fluid
12 Citations (Scopus)

Characterizations of chondrocyte attachment and proliferation on electrospun biodegradable scaffolds of PLLA and PBSA for use in cartilage tissue engineering

Wei, J. D., Tseng, H., Chen, E. T. H., Hung, C. H., Liang, Y-C., Sheu, M-T. & Chen, C-H., May 2012, In : Journal of Biomaterials Applications. 26, 8, p. 963-985 23 p.

Research output: Contribution to journalArticle

Cartilage
Lactic acid
Tissue engineering
Scaffolds
Lactic Acid
3 Citations (Scopus)
Pyrrolidinones
Polyethyleneimine
Hydrogels
Hydrogel
Fibrin Foam
35 Citations (Scopus)

Development of terbinafine solid lipid nanoparticles as a topical delivery system

Chen, Y. C., Liu, D. Z., Liu, J. J., Chang, T. W., Ho, H. O. & Sheu, M. T., 2012, In : International Journal of Nanomedicine. 7, p. 4409-4418 10 p.

Research output: Contribution to journalArticle

terbinafine
Nanoparticles
Lipids
Skin
Antifungal agents
2 Citations (Scopus)

Established HPLC fraction analysis to predict furanocoumarin-based herb-drug metabolic interactions

Sheu, M. T., Lin, Y. K., Huang, C. H. & Ho, H. O., Jun 2012, In : Phytotherapy Research. 26, 6, p. 865-877 13 p.

Research output: Contribution to journalArticle

Herb-Drug Interactions
Cytochrome P-450 CYP3A
High Pressure Liquid Chromatography
Reverse-Phase Chromatography
Chinese Traditional Medicine
6 Citations (Scopus)
Drug Delivery Systems
Gastrointestinal Tract
Polymers
Gases
Water
29 Citations (Scopus)
Cartilage
Scaffolds (biology)
Platelets
Fibrin
Tissue engineering
30 Citations (Scopus)

The Neuroprotective Effect of Platelet-rich Plasma on Erectile Function in Bilateral Cavernous Nerve Injury Rat Model

Wu, C. C., Wu, Y. N., Ho, H. O., Chen, K. C., Sheu, M. T. & Chiang, H-S., Nov 2012, In : Journal of Sexual Medicine. 9, 11, p. 2838-2848 11 p.

Research output: Contribution to journalArticle

Platelet-Rich Plasma
Neuroprotective Agents
Wounds and Injuries
Injections
Nerve Crush
4 Citations (Scopus)

Thermal analysis and dissolution characteristics of nifedipine solid dispersions

Wu, J. Y., Ho, H. O., Chen, Y. C., Chen, C. C. & Sheu, M. T., Mar 2012, In : Journal of Food and Drug Analysis. 20, 1

Research output: Contribution to journalArticle

thermal analysis
melting point
Nifedipine
crystallization
Hot Temperature
5 Citations (Scopus)

Wound-healing effect of micronized sacchachitin (mSC) nanogel on corneal epithelium

Chen, R. N., Lee, L. W., Chen, L. C., Ho, H. O., Lui, S. C., Sheu, M. T. & Su, C-H., 2012, In : International Journal of Nanomedicine. 7, p. 4697-4706 10 p.

Research output: Contribution to journalArticle

Corneal Epithelium
Cell proliferation
Wound Healing
Cell Proliferation
Proteolysis