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Personal profile


  • 2003 Ph.D. (Pharmacology), National Taiwan University


  • 2011 Associate Professor, Department of Pharmacology, School of Medicine, Taipei Medical University
  • 2007 Assistant Professor, Department of Pharmacology, School of Medicine, Taipei Medical University

Research Interests

  • Molecular Pharmacology, Angiogenesis, Signal transduction

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  • 9 Similar Profiles
Apoptosis Medicine & Life Sciences
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Cyclooxygenase 2 Medicine & Life Sciences
Smooth Muscle Myocytes Medicine & Life Sciences
p38 Mitogen-Activated Protein Kinases Medicine & Life Sciences
Protein Phosphatase 2 Medicine & Life Sciences
Endothelial cells Chemical Compounds

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Projects 2010 2019


Hsu, M.


Project: C - Project of Alliancen - Chi Mei Medical Center


Hsu, M.


Project: C - Project of Alliancen - Chi Mei Medical Center

Anti-Tumor Mechanisms of the Novel Series of Aliphatic Hydroxamate Derivatives, Wmj-J Compounds

Hsu, M.


Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 2000 2018

  • 1419 Citations
  • 25 h-Index
  • 56 Article
  • 1 Poster
  • 1 Review article

A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., Mar 1 2018, In : Frontiers in Pharmacology. 9, MAR, p. 1-17 17 p., 167.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Cell Death
4 Citations (Scopus)

CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation

Sheu, J. R., Chen, Z. C., Hsu, M. J., Wang, S. H., Jung, K. W., Wu, W. F., Pan, S. H., Teng, R. D., Yang, C. H. & Hsieh, C. Y., Feb 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 2, p. 999-1013 15 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Nitric Oxide Synthase Type II
4 Citations (Scopus)

Ketamine, a clinically used anesthetic, inhibits vascular smooth muscle cell proliferation via PP2A-activated PI3K/Akt/ERK inhibition

Chang, Y., Li, J. Y., Jayakumar, T., Hung, S. H., Lee, W. C., Manubolu, M., Sheu, J. R. & Hsu, M. J., Dec 1 2017, In : International Journal of Molecular Sciences. 18, 12, 2545.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Enzyme inhibition
smooth muscle
Protein Phosphatase 2
3 Citations (Scopus)

WMJ-8-B, a novel hydroxamate derivative, induces MDA-MB-231 breast cancer cell death via the SHP-1-STAT3-survivin cascade

Chuang, Y. F., Huang, S. W., Hsu, Y. F., Yu, M. C., Ou, G., Huang, W. J. & Hsu, M. J., 2017, (Accepted/In press) In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Cell Death
Breast Neoplasms
Genetic Promoter Regions
18 Citations (Scopus)
Heme Oxygenase-1
Endothelial cells
p38 Mitogen-Activated Protein Kinases