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Personal profile


  • 2003, Ph.D. (Pharmacology), National Taiwan University


  • 2011, Associate Professor, Department of Pharmacology, School of Medicine, Taipei Medical University
  • 2007, Assistant Professor, Department of Pharmacology, School of Medicine, Taipei Medical University

Research Interests

  • Molecular Pharmacology, Angiogenesis, Signal transduction

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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p38 Mitogen-Activated Protein Kinases Medicine & Life Sciences
Protein Phosphatase 2 Medicine & Life Sciences
MAP Kinase Kinase Kinase 5 Medicine & Life Sciences

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Projects 2010 2019

Research Output 2000 2018

  • 1486 Citations
  • 26 h-Index
  • 59 Article

A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., Mar 1 2018, In : Frontiers in Pharmacology. 9, MAR, 167.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Cell Death
3 Citations

CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation

Sheu, J. R., Chen, Z. C., Hsu, M. J., Wang, S. H., Jung, K. W., Wu, W. F., Pan, S. H., Teng, R. D., Yang, C. H. & Hsieh, C. Y., Feb 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 2, p. 999-1013 15 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Nitric Oxide Synthase Type II
4 Citations

Ketamine, a clinically used anesthetic, inhibits vascular smooth muscle cell proliferation via PP2A-activated PI3K/Akt/ERK inhibition

Chang, Y., Li, J. Y., Jayakumar, T., Hung, S. H., Lee, W. C., Manubolu, M., Sheu, J. R. & Hsu, M. J., Dec 1 2017, In : International Journal of Molecular Sciences. 18, 12, 2545.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Enzyme inhibition
smooth muscle
Protein Phosphatase 2
2 Citations

WMJ-8-B, a novel hydroxamate derivative, induces MDA-MB-231 breast cancer cell death via the SHP-1-STAT3-survivin cascade

Chuang, Y. F., Huang, S. W., Hsu, Y. F., Yu, M. C., Ou, G., Huang, W. J. & Hsu, M. J., 2017, (Accepted/In press) In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Cell Death
Breast Neoplasms
Genetic Promoter Regions
17 Citations
Heme Oxygenase-1
Endothelial cells
p38 Mitogen-Activated Protein Kinases