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Research Output

  • 2754 Citations
  • 29 h-Index
  • 112 Article
  • 2 Review article
  • 1 Comment/debate

3′UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma

Hua, K. T., Liu, Y. F., Hsu, C. L., Cheng, T. Y., Yang, C. Y., Chang, J. S., Lee, W. J., Hsiao, M., Juan, H. F., Chien, M. H. & Yang, S. F., Dec 1 2017, In : Scientific Reports. 7, 1, 4466.

Research output: Contribution to journalArticle

28 Citations (Scopus)
5 Citations (Scopus)

Antimetastatic effects of norcantharidin on hepatocellular carcinoma by transcriptional inhibition of MMP-9 through modulation of NF-Kb activity

Yeh, C. B., Hsieh, M. J., Hsieh, Y. H., Chien, M. H., Chiou, H. L. & Yang, S. F., Feb 7 2012, In : PLoS One. 7, 2, e31055.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Association of EGFR mutations and HMGB1 genetic polymorphisms in lung adenocarcinoma patients

Wu, Y. L., Chien, M. H., Chou, Y. E., Chang, J. H., Liu, T. C., Tsao, T. C. Y., Chou, M. C. & Yang, S. F., Jan 1 2019, In : Journal of Cancer. 10, 13, p. 2907-2914 8 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Associations of genetic variations of the endothelial nitric oxide synthase gene and environmental carcinogens with oral cancer susceptibility and development

Su, C. W., Chien, M. H., Lin, C. W., Chen, M. K., Chow, J. M., Chuang, C. Y., Chou, C. H., Liu, Y. C. & Yang, S. F., Sep 1 2018, In : Nitric Oxide - Biology and Chemistry. 79, p. 1-7 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Associations of VEGF-C genetic polymorphisms with urothelial cell carcinoma susceptibility differ between smokers and non-smokers in Taiwan

Tung, M. C., Hsieh, M. J., Wang, S. S., Yang, S. F., Chen, S. S., Wang, S. W., Lee, L. M., Lee, W. J. & Chien, M. H., Mar 7 2014, In : PLoS One. 9, 3, e91147.

Research output: Contribution to journalArticle

13 Citations (Scopus)
Open Access
1 Citation (Scopus)

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer

Wen, Y-C., Lee, W. J., Tan, P., Yang, S. F., Hsiao, M., Lee, L. M. & Chien, M. H., 2015, In : Oncotarget. 6, 25, p. 21120-21136 17 p.

Research output: Contribution to journalArticle

Open Access
46 Citations (Scopus)

Cantharidic acid induces apoptosis of human leukemic HL-60 cells via c-Jun N-terminal kinase-regulated caspase-8/-9/-3 activation pathway

Wang, S. C., Chow, J. M., Chien, M. H., Lin, C. W., Chen, H. Y., Hsiao, P. C. & Yang, S. F., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

16 Citations (Scopus)
3 Citations (Scopus)

Circulating level of lipocalin 2 as a predictor of severity in patients with community-acquired pneumonia

Yeh, Y. H., Chang, J. L., Hsiao, P. C., Tsao, S. M., Lin, C. H., Kao, S. J., Chou, M. C., Yang, S. F. & Chien, M. H., Jul 2013, In : Journal of Clinical Laboratory Analysis. 27, 4, p. 253-260 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Circulating proteoglycan endocan mediates EGFR-driven progression of non-small cell lung cancer

Yang, Y-C., Pan, K-F., Lee, W-J., Chang, J-H., Tan, P., Gu, C-C., Chang, W-M., Yang, S-F., Hsiao, M., Hua, K-T. & Chien, M-H., Jun 19 2020, In : Cancer Research.

Research output: Contribution to journalArticle

Clinical implications of aldo-keto reductase family 1 member C3 and its relationship with lipocalin 2 in cancer of the uterine cervix

Wu, C. H., Ko, J. L., Chen, S. C., Lin, Y. W., Han, C. P., Yang, T. Y., Chien, M. H. & Wang, P. H., Feb 2014, In : Gynecologic Oncology. 132, 2, p. 474-482 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Combined Effects of ICAM-1 Single-Nucleotide Polymorphisms and Environmental Carcinogens on Oral Cancer Susceptibility and Clinicopathologic Development

Lin, C. W., Chuang, C. Y., Tang, C. H., Chang, J. L., Lee, L-M., Lee, W-J., Chow, J-M., Yang, S. F. & Chien, M-H., Sep 12 2013, In : PLoS One. 8, 9, e72940.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Connective tissue growth factor induces collagen I expression in human lung fibroblasts through the Rac1/MLK3/JNK/AP-1 pathway

Lin, C. H., Yu, M. C., Tung, W. H., Chen, T. T., Yu, C. C., Weng, C. M., Tsai, Y. J., Bai, K. J., Hong, C. Y., Chien, M. H. & Chen, B. C., Dec 2013, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1833, 12, p. 2823-2833 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Correlation of chitinase 3-like 1 single nucleotide polymorphisms and haplotypes with uterine cervical cancer in Taiwanese women

Lin, Y. S., Liu, Y. F., Chou, Y. E., Yang, S. F., Chien, M. H., Wu, C. H., Chou, C. H., Cheng, C. W. & Wang, P. H., 2014, In : PLoS One. 9, 9, p. e104038

Research output: Contribution to journalArticle

10 Citations (Scopus)

Corrigendum to "Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells" [383 (2016) 282-294]

Kuo, T. C., Chen, C. K., Hua, K. T., Yu, P., Lee, W. J., Chen, M. W., Jeng, Y. M., Chien, M. H., Kuo, K. T., Hsiao, M. & Kuo, M. L., 2017, (Accepted/In press) In : Cancer Letters.

Research output: Contribution to journalArticle

CYR61 regulates BMP-2-dependent osteoblast differentiation through the αvβ3 integrin/integrin-linked kinase/ERK pathway

Su, J. L., Chiou, J., Tang, C. H., Zhao, M., Tsai, C. H., Chen, P. S., Chang, Y. W., Chien, M. H., Peng, C. Y., Hsiao, M., Kuo, M. L. & Yenk, M. L., Oct 8 2010, In : Journal of Biological Chemistry. 285, 41, p. 31325-31336 12 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 activity

Chien, M. H., Ying, T. H., Hsieh, Y. S., Chang, Y. C., Yeh, C. M., Ko, J. L., Lee, W. S., Chang, J. H. & Yang, S. F., Mar 2012, In : Food and Chemical Toxicology. 50, 3-4, p. 558-566 9 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Diversity-oriented synthesis of angular bis-benzimidazole derivatives under microwave irradiation

Chen, C. H., Chien, M. H., Kuo, M. L., Chou, C. T., Lai, J. J., Lin, S. F., Thummanagoti, S. & Sun, C. M., Nov 9 2009, In : Journal of Combinatorial Chemistry. 11, 6, p. 1038-1046 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Dopamine receptor D2 genetic variations is associated with the risk and clinicopathological variables of urothelial cell carcinoma in a taiwanese population

Tung, M. C., Wen, Y. C., Wang, S. S., Lin, Y. W., Liu, Y. C., Yang, S. F. & Chien, M. H., Jul 30 2018, In : International Journal of Medical Sciences. 15, 11, p. 1187-1193 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
16 Citations (Scopus)

Dual targeting of the p38 MAPK‐HO‐1 axis and cIAP1/XIAP by demethoxycurcumin triggers caspase‐mediated apoptotic cell death in oral squamous cell carcinoma cells

Chien, M. H., Yang, W. E., Yang, Y. C., Ku, C. C., Lee, W. J., Tsai, M. Y., Lin, C. W. & Yang, S. F., Mar 2020, In : Cancers. 12, 3, 703.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Effect of CC chemokine ligand 5 and CC chemokine receptor 5 genes polymorphisms on the risk and clinicopathological development of oral cancer

Weng, C. J., Chien, M. H., Lin, C. W., Chung, T. T., Zavras, A. I., Tsai, C. M., Chen, M. K. & Yang, S. F., Oct 2010, In : Oral Oncology. 46, 10, p. 767-772 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Effect of RECK gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathologic features

Chung, T. T., Yeh, C. B., Li, Y. C., Su, S. C., Chien, M. H., Yang, S. F. & Hsieh, Y. H., Mar 12 2012, In : PLoS One. 7, 3, e33517.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Effects of E-cadherin (CDH1) gene promoter polymorphisms on the risk and clinicopathological development of hepatocellular carcinoma

Chien, M. H., Yeh, K. T., Li, Y. C., Hsieh, Y. H., Lin, C-H., Weng, M. S., Kuo, W. H. & Yang, S. F., Sep 1 2011, In : Journal of Surgical Oncology. 104, 3, p. 299-304 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Effects of E-cadherin (CDH1) gene promoter polymorphisms on the risk and clinicopathologic development of oral cancer

Chien, M. H., Chou, L. S. S., Chung, T. T., Lin, C. H., Chou, M. Y., Weng, M. S., Yang, S. F. & Chen, M. K., Mar 2012, In : Head and Neck. 34, 3, p. 405-411 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Effects of metallothionein-1 genetic polymorphism and cigarette smoking on the development of hepatocellular carcinoma

Wong, R. H., Huang, C. H., Yeh, C. B., Lee, H. S., Chien, M. H. & Yang, S. F., Jun 2013, In : Annals of Surgical Oncology. 20, 6, p. 2088-2095 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Effects of NFKB1 and NFKBIA Gene Polymorphisms on Hepatocellular Carcinoma Susceptibility and Clinicopathological Features

Cheng, C. W., Su, J. L., Lin, C. W., Su, C. W., Shih, C. H., Yang, S. F. & Chien, M. H., Feb 14 2013, In : PLoS One. 8, 2, e56130.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Effects of NFKB1 and NFKBIA gene polymorphisms on susceptibility to environmental factors and the clinicopathologic development of oral cancer

Lin, C. W., Hsieh, Y. S., Hsin, C. H., Su, C. W., Lin, C-H., Wei, L. H., Yang, S. F. & Chien, M. H., 2012, In : PLoS One. 7, 4, e35078.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Elevated plasma matrix metalloproteinase-9 protein and its gene polymorphism in patients with community-acquired pneumonia

Chiang, T. Y., Shyu, L. Y., Tsao, T. C. Y., Chien, M. H., Tsao, S. M., Lee, Y. T. & Yang, S. F., Mar 1 2012, In : Clinical Chemistry and Laboratory Medicine. 50, 3, p. 449-454 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Expression of carbonic anhydrases I/II and the correlation to clinical aspects of oral squamous cell carcinoma analyzed using tissue microarray

Liu, C. M., Lin, Y. M., Yeh, K. T., Chen, M. K., Chang, J. H., Chen, C. J., Chou, M. Y., Yang, S. F. & Chien, M. H., Aug 2012, In : Journal of Oral Pathology and Medicine. 41, 7, p. 533-539 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Further Evidence for Expression and Function of the VEGF-C/VEGFR-3 Axis in Cancer Cells

Su, J. L., Chen, P. S., Chien, M. H., Chen, P. B., Chen, Y. H., Lai, C. C., Hung, M. C. & Kuo, M. L., Jun 10 2008, In : Cancer Cell. 13, 6, p. 557-560 4 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

G2/M cell cycle arrest and tumor selective apoptosis of acute leukemia cells by a promising benzophenone thiosemicarbazone compound

Cabrera, M., Gomez, N., Lenicov, F. R., Echeverría, E., Shayo, C., Moglioni, A., Fernández, N., Davio, C. & Chien, M. H., Sep 11 2015, In : PLoS One. 10, 9, 0136878.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2 Citations (Scopus)

Glabridin mediate caspases activation and induces apoptosis through JNK1/2 and p38 MAPK pathway in human promyelocytic leukemia cells

Huang, H. L., Hsieh, M. J., Chien, M. H., Chen, H. Y., Yang, S. F. & Hsiao, P. C., Jun 5 2014, In : PLoS One. 9, 6, e98943.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells

Kuo, T. C., Chen, C. K., Hua, K. T., Yu, P., Lee, W-J., Chen, M. W., Jeng, Y. M., Chien, M-H., Kuo, K., Hsiao, M. & Kuo, M. L., Dec 28 2016, In : Cancer Letters. 383, 2, p. 282-294 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM

Chen, M. W., Hua, K. T., Kao, H. J., Chi, C. C., Wei, L. H., Johansson, G., Shiah, S. G., Chen, P. S., Jeng, Y. M., Cheng, T. Y., Lai, T. C., Chang, J. S., Jan, Y. H., Chien, M. H., Yang, C. J., Huang, M. S., Hsiao, M. & Kuo, M. L., Oct 15 2010, In : Cancer Research. 70, 20, p. 7830-7840 11 p.

Research output: Contribution to journalArticle

216 Citations (Scopus)
33 Citations (Scopus)

Impact of interleukin-8 gene polymorphisms and environmental factors on oral cancer susceptibility in Taiwan

Liu, C. M., Yeh, C. J., Yu, C. C., Chou, M. Y., Lin, C-H., Wei, L. H., Lin, C. W., Yang, S. F. & Chien, M. H., Apr 2012, In : Oral Diseases. 18, 3, p. 307-314 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Impact of VEGF-C Gene Polymorphisms and Environmental Factors on Oral Cancer Susceptibility in Taiwan

Chien, M. H., Liu, Y. F., Hsin, C. H., Lin, C-H., Shih, C. H., Yang, S. F., Cheng, C. W. & Lin, C. W., Apr 4 2013, In : PLoS One. 8, 4, e60283.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Impacts of CA9 Gene Polymorphisms and Environmental Factors on Oral-Cancer Susceptibility and Clinicopathologic Characteristics in Taiwan

Chien, M. H., Yang, J. S., Chu, Y. H., Lin, C-H., Wei, L. H., Yang, S. F. & Lin, C. W., Dec 4 2012, In : PLoS One. 7, 12, e51051.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Impacts of microRNA gene polymorphisms on the susceptibility of environmental factors leading to carcinogenesis in oral cancer

Chu, Y. H., Tzeng, S. L., Lin, C. W., Chien, M. H., Chen, M. K. & Yang, S. F., Jun 28 2012, In : PLoS One. 7, 6, e39777.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Increased expression of carbonic anhydrase IX in oral submucous fibrosis and oral squamous cell carcinoma

Yang, J. S., Chen, M. K., Yang, S. F., Chang, Y. C., Su, S. C., Chiou, H. L., Chien, M. H. & Lin, C. W., Sep 1 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 9, p. 1367-1377 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Induction of p21Waf1/Cip1 by garcinol via downregulation of p38-MAPK signaling in p53-independent H1299 lung cancer

Yu, S. Y., Liao, C. H., Chien, M. H., Tsai, T. Y., Lin, J. K. & Weng, M. S., Mar 5 2014, In : Journal of Agricultural and Food Chemistry. 62, 9, p. 2085-2095 11 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
47 Citations (Scopus)

Inhibition of metastatic potential in breast carcinoma in vivo and in vitro through targeting VEGFRs and FGFRs

Chien, M. H., Lee, L. M., Hsiao, M., Wei, L. H., Chen, C. H., Lai, T. C., Hua, K. T., Chen, M. W., Sun, C. M. & Kuo, M. L., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 718380.

Research output: Contribution to journalArticle

7 Citations (Scopus)