Projects per year
Personal profile
Education
- 2000-2005 Ph.D., Graduate Institute of Medical Sciences, Taipei Medical University
- 1998-2000 M.S., School of Medical Laboratory Science and Biotechnology, Taipei Medical University
- 1994-1998 B.S., School of Medical Laboratory and Biotechnology, Chung Shan Medical University
Experience
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.02- Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2013.02-2016.01 Associate Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2010.02-2013.01 Assitant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2009.11- Medical research fellow, Department of Education and Research, Wan Fang Hospital, Taipei Medical University
- 2005.09-2009.09 Postdoctoral associate, Laboratory of Molecular and Cellular Toxicology, Institute of Toxicology, College of Medicine and Angiogenesis Research Center, National Taiwan University
Research Interests
- Molecular Oncology
- Anti-cancer Drug Development
- Translational Laboratory Science
Awards
- 2015國際轉譯醫學新知研討會：食品科學、環境毒理學和癌症生物學壁報論文獎(第二名)
- 2014年臺北醫學大學最具影響力論文獎
- 2014年臺北醫學大學師生聯合學術研究發表會優秀論文獎(第二名)
- 2013年臺北醫學大學最具影響力論文獎
- 2013年臺北醫學大學年輕學者研究獎
- 2012年台灣藥理學會杜聰明博士年輕學者獎
- 2012年臺北醫學大學研究論文優良獎
- 2012年萬芳醫學中心論文獎(第二名)
- 2012年萬芳醫學中心論文獎(第一名)
- 2011年臺北醫學大學年輕學者研究獎
- 2011年萬芳醫學中心論文獎(第三名)
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Projects
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探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(1/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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探討第一型內皮細胞分子與上皮細胞生長因子受體之相互調控在非小細胞肺癌進程之角色(3/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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探討第一型內皮細胞分子胃癌進程之角色及相關調控機制
3/1/20 → 2/1/21
Project: C - Project of Alliance › n - Yuan's General Hospital
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The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
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利用全基因定序尋找肝癌其體細胞突變基因和基因多型性與環境因子之關聯-聚焦於長鏈非編碼核糖核酸MALAT1之基因多型性探討
3/1/19 → 2/1/20
Project: C - Project of Alliance › n - Yuan's General Hospital
Research output
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Associations of timp-3 genetic polymorphisms with egfr statuses and cancer clinicopathologic development in lung adenocarcinoma patients
Chang, J. H., Lai, T. C., Yang, P. J., Shih, P. C., Yang, Y. C., Lee, K. L., Liu, T. C., Chang-Yao Tsao, T., Yang, S. F. & Chien, M. H., Nov 1 2020, In: International journal of molecular sciences. 21, 21, p. 1-13 13 p., 8023.Research output: Contribution to journal › Article › peer-review
Open Access -
Circulating proteoglycan endocan mediates EGFR-driven progression of non-small cell lung cancer
Yang, Y-C., Pan, K-F., Lee, W-J., Chang, J-H., Tan, P., Gu, C-C., Chang, W-M., Yang, S-F., Hsiao, M., Hua, K-T. & Chien, M-H., Jun 19 2020, (E-pub ahead of print) In: Cancer Research.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Correction to: Liu, h.w.; et al. enhanced hsa-mir-181d/p-stat3 and hsa-mir-181d/p-stat5a ratios mediate the anticancer effect of garcinol in stat3/5a-addicted glioblastoma. cancers 2019, 11, 1888
Liu, H. W., Lee, P. M., Bamodu, O. A., Su, Y. K., Fong, I. H., Yeh, C-T., Chien, M-H., Kan, I-H. & Lin, C-M., Oct 2020, In: Cancers. 12, 10, p. 1-4 4 p., 2846.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Dual targeting of the p38 MAPK‐HO‐1 axis and cIAP1/XIAP by demethoxycurcumin triggers caspase‐mediated apoptotic cell death in oral squamous cell carcinoma cells
Chien, M. H., Yang, W. E., Yang, Y. C., Ku, C. C., Lee, W. J., Tsai, M. Y., Lin, C. W. & Yang, S. F., Mar 2020, In: Cancers. 12, 3, 703.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Melatonin-triggered post-transcriptional and post-translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma
Wen, Y. C., Lin, Y. W., Chu, C. Y., Yang, Y. C., Yang, S. F., Liu, Y. F., Hsiao, M., Lee, W. J. & Chien, M. H., Sep 1 2020, In: Journal of Pineal Research. 69, 2, e12668.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)
Datasets
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v1, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/1
Dataset
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Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses
Wu, S. (Contributor), Wen, Y. (Contributor), Ku, C. (Contributor), Yang, Y. (Contributor), Chow, J. (Contributor), Yang, S. (Contributor), Lee, W. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Aug 31 2019
DOI: 10.6084/m9.figshare.c.4650602.v1, https://springernature.figshare.com/collections/Penfluridol_triggers_cytoprotective_autophagy_and_cellular_apoptosis_through_ROS_induction_and_activation_of_the_PP2A-modulated_MAPK_pathway_in_acute_myeloid_leukemia_with_different_FLT3_statuses/4650602/1
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v2, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/2
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v3, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/3
Dataset
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Additional file 1: of Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses
Wu, S. (Contributor), Wen, Y. (Contributor), Ku, C. (Contributor), Yang, Y. (Contributor), Chow, J. (Contributor), Yang, S. (Contributor), Lee, W. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Aug 31 2019
DOI: 10.6084/m9.figshare.9756398.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Penfluridol_triggers_cytoprotective_autophagy_and_cellular_apoptosis_through_ROS_induction_and_activation_of_the_PP2A-modulated_MAPK_pathway_in_acute_myeloid_leukemia_with_different_FLT3_statuses/9756398/1
Dataset