Projects per year
Personal profile
Education
- 2000-2005 Ph.D., Graduate Institute of Medical Sciences, Taipei Medical University
- 1998-2000 M.S., School of Medical Laboratory Science and Biotechnology, Taipei Medical University
- 1994-1998 B.S., School of Medical Laboratory and Biotechnology, Chung Shan Medical University
Experience
- 2021.08- Vice Dean, Office of Research and Development, Taipei Medical University
- 2020.08- Distinguished Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.02- Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2013.02-2016.01 Associate Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2010.02-2013.01 Assitant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2009.11- Medical research fellow, Department of Education and Research, Wan Fang Hospital, Taipei Medical University
- 2005.09-2009.09 Postdoctoral associate, Laboratory of Molecular and Cellular Toxicology, Institute of Toxicology, College of Medicine and Angiogenesis Research Center, National Taiwan University
Research Interests
- Molecular Oncology
- Anti-cancer Drug Development
- Translational Laboratory Science
Awards
- 2020年 台灣藥理學會李鎮源教授傑出研究獎
- 2020年 臺北醫學大學年度研究成就獎
- 2020年 臺北醫學大學國際頂尖期刊論文獎
- 2020年 臺北醫學大學研究論文傑出獎
- 2015-2018年 臺北醫學大學研究論文優良獎
Fingerprint
Dive into the research topics where Ming-Hsien Chien is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(2/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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探討第一型內皮細胞分子與上皮細胞生長因子受體之相互調控在非小細胞肺癌進程之角色(3/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(1/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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探討第一型內皮細胞分子胃癌進程之角色及相關調控機制
3/1/20 → 2/1/21
Project: C - Project of Alliance › n - Yuan's General Hospital
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The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
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Proteoglycan Endocan: A multifaceted therapeutic target in Cancer
Pan, K. F., Yang, Y. C., Lee, W. J., Hua, K. T. & Chien, M. H., Jan 2022, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1877, 1, 188672.Research output: Contribution to journal › Review article › peer-review
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Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis
Tung, M. C., Lin, Y. W., Lee, W. J., Wen, Y. C., Liu, Y. C., Chen, J. Q., Hsiao, M., Yang, Y. C. & Chien, M. H., Apr 2022, In: Cell Death and Disease. 13, 4, 400.Research output: Contribution to journal › Article › peer-review
Open Access -
Blocking MMP-12-modulated epithelial-mesenchymal transition by repurposing penfluridol restrains lung adenocarcinoma metastasis via uPA/uPAR/TGF-β/Akt pathway
Hung, W. Y., Lee, W. J., Cheng, G. Z., Tsai, C. H., Yang, Y. C., Lai, T. C., Chen, J. Q., Chung, C. L., Chang, J. H. & Chien, M. H., Oct 2021, In: Cellular Oncology. 44, 5, p. 1087-1103 17 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Combined Impacts of Genetic Variants of Long Non-Coding RNA MALAT1 and the Environmental Carcinogen on the Susceptibility to and Progression of Oral Squamous Cell Carcinoma
Ding, Y. F., Wen, Y. C., Chuang, C. Y., Lin, C. W., Yang, Y. C., Liu, Y. F., Chang, W. M., Chang, L. C., Yang, S. F. & Chien, M. H., Jun 2021, In: Frontiers in Oncology. 11, 684941.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Direct interaction of β-catenin with nuclear ESM1 supports stemness of metastatic prostate cancer
Pan, K. F., Lee, W. J., Chou, C. C., Yang, Y. C., Chang, Y. C., Chien, M. H., Hsiao, M. & Hua, K. T., Feb 15 2021, In: EMBO Journal. 40, 4, e105450.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)
Datasets
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v3, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/3
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v2, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/2
Dataset
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CCDC 783608: Experimental Crystal Structure Determination
Chanda, K. (Contributor), Maiti, B. (Contributor), Yellol, G. S. (Contributor), Chien, M. (Contributor), Kuo, M. (Contributor) & Sun, C. (Contributor), Unknown Publisher, Jan 1 2011
DOI: 10.5517/ccv9dp6, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccv9dp6&sid=DataCite
Dataset
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Additional file 1: of Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses
Chang, J. (Contributor), Cheng, C. (Contributor), Yang, Y. (Contributor), Chen, W. (Contributor), Hung, W. (Contributor), Chow, J. (Contributor), Chen, P. (Contributor), Hsiao, M. (Contributor), Lee, W. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Aug 22 2018
DOI: 10.6084/m9.figshare.6999656.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Downregulating_CD26_DPPIV_by_apigenin_modulates_the_interplay_between_Akt_and_Snail_Slug_signaling_to_restrain_metastasis_of_lung_cancer_with_multiple_EGFR_statuses/6999656/1
Dataset
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Additional file 1: of Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses
Wu, S. (Contributor), Wen, Y. (Contributor), Ku, C. (Contributor), Yang, Y. (Contributor), Chow, J. (Contributor), Yang, S. (Contributor), Lee, W. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Aug 31 2019
DOI: 10.6084/m9.figshare.9756398.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Penfluridol_triggers_cytoprotective_autophagy_and_cellular_apoptosis_through_ROS_induction_and_activation_of_the_PP2A-modulated_MAPK_pathway_in_acute_myeloid_leukemia_with_different_FLT3_statuses/9756398/1
Dataset