Projects per year
Personal profile
Education
- 2000-2005 Ph.D., Graduate Institute of Medical Sciences, Taipei Medical University
- 1998-2000 M.S., School of Medical Laboratory Science and Biotechnology, Taipei Medical University
- 1994-1998 B.S., School of Medical Laboratory and Biotechnology, Chung Shan Medical University
Experience
- 2021.08- Vice Dean, Office of Research and Development, Taipei Medical University
- 2020.08- Distinguished Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.02- Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2013.02-2016.01 Associate Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2010.02-2013.01 Assitant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2009.11- Medical research fellow, Department of Education and Research, Wan Fang Hospital, Taipei Medical University
- 2005.09-2009.09 Postdoctoral associate, Laboratory of Molecular and Cellular Toxicology, Institute of Toxicology, College of Medicine and Angiogenesis Research Center, National Taiwan University
Research Interests
- Molecular Oncology
- Anti-cancer Drug Development
- Translational Laboratory Science
Awards
- 2020年 台灣藥理學會李鎮源教授傑出研究獎
- 2020年 臺北醫學大學年度研究成就獎
- 2020年 臺北醫學大學國際頂尖期刊論文獎
- 2020年 臺北醫學大學研究論文傑出獎
- 2015-2018年 臺北醫學大學研究論文優良獎
Fingerprint
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Network
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Projects
- 18 Finished
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探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(1/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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探討第一型內皮細胞分子與上皮細胞生長因子受體之相互調控在非小細胞肺癌進程之角色(3/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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探討第一型內皮細胞分子胃癌進程之角色及相關調控機制
3/1/20 → 2/1/21
Project: C - Project of Alliance › n - Yuan's General Hospital
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The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
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利用全基因定序尋找肝癌其體細胞突變基因和基因多型性與環境因子之關聯-聚焦於長鏈非編碼核糖核酸MALAT1之基因多型性探討
3/1/19 → 2/1/20
Project: C - Project of Alliance › n - Yuan's General Hospital
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Direct interaction of β-catenin with nuclear ESM1 supports stemness of metastatic prostate cancer
Pan, K. F., Lee, W. J., Chou, C. C., Yang, Y. C., Chang, Y. C., Chien, M. H., Hsiao, M. & Hua, K. T., Feb 15 2021, In: EMBO Journal. 40, 4, e105450.Research output: Contribution to journal › Article › peer-review
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Histone methyltransferase g9a-promoted progression of hepatocellular carcinoma is targeted by liver-specific hsa-mir-122
Yuan, L. T., Lee, W. J., Yang, Y. C., Chen, B. R., Yang, C. Y., Chen, M. W., Chen, J. Q., Hsiao, M., Chien, M. H. & Hua, K. T., May 2 2021, In: Cancers. 13, 10, 2376.Research output: Contribution to journal › Article › peer-review
Open Access -
Potential impacts of interleukin-17a promoter polymorphisms on the egfr mutation status and progression of non-small cell lung cancer in Taiwan
Lee, K. L., Lai, T. C., Wang, Y. C., Shih, P. C., Yang, Y. C., Tsao, T. C. Y., Liu, T. C., Wen, Y. C., Chang, L. C., Yang, S. F. & Chien, M. H., Mar 2021, In: Genes. 12, 3, 427.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteomics-based identification of TMED9 is linked to vascular invasion and poor prognoses in patients with hepatocellular carcinoma
Yang, Y. C., Chien, M. H., Lai, T. C., Tung, M. C., Jan, Y. H., Chang, W. M., Jung, S. M., Chen, M. H., Yeh, C. N. & Hsiao, M., Dec 2021, In: Journal of Biomedical Science. 28, 1, 29.Research output: Contribution to journal › Article › peer-review
Open Access -
Associations of timp-3 genetic polymorphisms with egfr statuses and cancer clinicopathologic development in lung adenocarcinoma patients
Chang, J. H., Lai, T. C., Yang, P. J., Shih, P. C., Yang, Y. C., Lee, K. L., Liu, T. C., Chang-Yao Tsao, T., Yang, S. F. & Chien, M. H., Nov 1 2020, In: International journal of molecular sciences. 21, 21, p. 1-13 13 p., 8023.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Datasets
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Additional file 1: of Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
Chien, M. (Contributor), Lin, Y. (Contributor), Wen, Y. (Contributor), Yang, Y. (Contributor), Hsiao, M. (Contributor), Chang, J. (Contributor), Huang, H. (Contributor) & Lee, W. (Contributor), Unknown Publisher, Jun 10 2019
DOI: 10.6084/m9.figshare.8252111.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Targeting_the_SPOCK1-snail_slug_axis-mediated_epithelial-to-mesenchymal_transition_by_apigenin_contributes_to_repression_of_prostate_cancer_metastasis/8252111/1
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v2, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/2
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J. (Contributor), Hsieh, Y. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Hsieh, F. (Contributor), Yu, N. (Contributor), Chou, M. (Contributor), Cheng, C. (Contributor), Yang, S. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Jan 1 2015
DOI: 10.6084/m9.figshare.1568934.v3, https://tandf.figshare.com/articles/journal_contribution/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/3
Dataset
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CCDC 783608: Experimental Crystal Structure Determination
Chanda, K. (Contributor), Maiti, B. (Contributor), Yellol, G. S. (Contributor), Chien, M. (Contributor), Kuo, M. (Contributor) & Sun, C. (Contributor), Unknown Publisher, Jan 1 2011
DOI: 10.5517/ccv9dp6, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccv9dp6&sid=DataCite
Dataset
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Additional file 1: of Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses
Wu, S. (Contributor), Wen, Y. (Contributor), Ku, C. (Contributor), Yang, Y. (Contributor), Chow, J. (Contributor), Yang, S. (Contributor), Lee, W. (Contributor) & Chien, M. (Contributor), Unknown Publisher, Aug 31 2019
DOI: 10.6084/m9.figshare.9756398.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Penfluridol_triggers_cytoprotective_autophagy_and_cellular_apoptosis_through_ROS_induction_and_activation_of_the_PP2A-modulated_MAPK_pathway_in_acute_myeloid_leukemia_with_different_FLT3_statuses/9756398/1
Dataset