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Fingerprint Dive into the research topics where Mei-Jung Lai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 15 Similar Profiles
Histone Deacetylase Inhibitors Medicine & Life Sciences
Histone Deacetylases Medicine & Life Sciences
Hydroxamic Acids Medicine & Life Sciences
Cells Chemical Compounds
Tubulin Medicine & Life Sciences
Heterografts Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences
Inhibitory Concentration 50 Medicine & Life Sciences

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Projects 2014 2019

Design and Synthesis of Biaryl and Biphenylamino Sulfonamides as Novel Anticancer Agents

Lai, M.

8/1/167/31/17

Project: A - Government Institutionb - Ministry of Science and Technology

設計與合成新穎苯甲醯胺與醯基羥胺取代之雜環化合物分別抑制微小管與組織蛋白去乙醯酉每6為抗癌藥物

Lai, M.

11/1/1410/31/15

Project: A - Government Institutionb - Ministry of Science and Technology

TMU103-AE1-B09

Lai, M.

11/1/1410/31/16

Project: B - Project of TMUg - Research Grants for Newly Hired Faculty

Research Output 2016 2020

  • 68 Citations
  • 5 h-Index
  • 10 Article

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111915.

Research output: Contribution to journalArticle

Azepines
Histone Deacetylase Inhibitors
Blood Vessels
Acetylation
Acrylamide
5 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
1 Citation (Scopus)
Growth Inhibitors
Amides
Prostatic Neoplasms
Cells
Lead compounds
2 Citations (Scopus)

Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

Chao, M. W., Chang, L. H., Tu, H. J., Chang, C. D., Lai, M. J., Chen, Y. Y., Liou, J. P., Teng, C. M. & Pan, S. L., May 29 2019, In : Clinical Epigenetics. 11, 1, 85.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylase Inhibitors
Mitogen-Activated Protein Kinase Kinases
Pancreatic Neoplasms
Epidermal Growth Factor Receptor
Heterografts
10 Citations (Scopus)

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., Apr 25 2018, In : European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.

Research output: Contribution to journalArticle

Hydroxamic Acids
Histone Deacetylase Inhibitors
Antineoplastic Agents
Protein Isoforms
Cells