Mei-Jung Lai

Associate Research Fellow, TMU Biomedical Commercialization Center
Joint-Appointment Associate Research Fellow, Ph.D. Program in Drug Discovery and Development Industry

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

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1 Active
4 Finished

合成可雙重抑制組織蛋白去乙醯酶6與熱休克蛋白90，並同時調節PD-L1之雜環類抗癌化合物
Lai, M.
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
組蛋白去乙醯酶在血管認知功能損傷中的作用-組蛋白去乙醯酶調節者在血管認知損傷動物可作為新的治療
Lai, M.
1/1/19 → 12/1/19
Project: A - Government Institution › d - Ministry of Education
Design and Synthesis of Biaryl and Biphenylamino Sulfonamides as Novel Anticancer Agents
Lai, M.
8/1/16 → 7/31/17
Project: A - Government Institution › b - Ministry of Science and Technology
TMU103-AE1-B09
Lai, M.
11/1/14 → 10/31/16
Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty
設計與合成新穎苯甲醯胺與醯基羥胺取代之雜環化合物分別抑制微小管與組織蛋白去乙醯酉每6為抗癌藥物
Lai, M.
11/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology

594 Citations
16 h-Index
41 Article
3 Comment/debate

CAP rigidification of MS-275 and chidamide leads to enhanced antiproliferative effects mediated through HDAC1, 2 and tubulin polymerization inhibition
Singh, A., Chang, T. Y., Kaur, N., Hsu, K. C., Yen, Y., Lin, T. E., Lai, M. J., Lee, S. B. & Liou, J. P., Apr 5 2021, In: European Journal of Medicinal Chemistry. 215, 113169.
Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)
Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms
Mehndiratta, S., Chen, M. C., Chao, Y. H., Lee, C. H., Liou, J. P., Lai, M. J. & Lee, H. Y., Dec 2021, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 74-84 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma
Nepali, K., Hsu, T. I., Hsieh, C. M., Lo, W. L., Lai, M. J., Hsu, K. C., Lin, T. E., Chuang, J. Y. & Liou, J. P., May 5 2021, In: European Journal of Medicinal Chemistry. 217, 113338.
Research output: Contribution to journal › Article › peer-review
Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as HSP90 inhibitors suppressing tumor growth in vitro and in vivo
Liu, Y. M., Tu, H. J., Wu, C. H., Lai, M. J., Yu, S. C., Chao, M. W., Wu, Y. W., Teng, C. M., Pan, S. L. & Liou, J. P., Jul 5 2021, In: European Journal of Medicinal Chemistry. 219, 113428.
Research output: Contribution to journal › Article › peer-review
Corrigendum to “1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma” [Eur. J. Med. Chem. 140 (2017) 84–91](S0223523417306931)(10.1016/j.ejmech.2017.09.011)
Liu, Y. M., HuangFu, W. C., Huang, H. L., Wu, W. C., Chen, Y. L., Yen, Y., Huang, H. L., Nien, C. Y., Lai, M. J., Pan, S. L. & Liou, J. P., Sep 15 2020, In: European Journal of Medicinal Chemistry. 202, 112633.
Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Additional file 5: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chao, M. (Contributor), Chang, L. (Contributor), Tu, H. (Contributor), Chang, C. (Contributor), Lai, M. (Contributor), Chen, Y. (Contributor), Liou, J. (Contributor), Teng, C. (Contributor) & Pan, S. (Contributor), Unknown Publisher, May 29 2019
DOI: 10.6084/m9.figshare.8202902.v1, https://springernature.figshare.com/articles/Additional_file_5_of_Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/8202902/1
Dataset
Additional file 3: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chao, M. (Contributor), Chang, L. (Contributor), Tu, H. (Contributor), Chang, C. (Contributor), Lai, M. (Contributor), Chen, Y. (Contributor), Liou, J. (Contributor), Teng, C. (Contributor) & Pan, S. (Contributor), Unknown Publisher, May 29 2019
DOI: 10.6084/m9.figshare.8202890.v1, https://springernature.figshare.com/articles/Additional_file_3_of_Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/8202890/1
Dataset
Additional file 4: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chao, M. (Contributor), Chang, L. (Contributor), Tu, H. (Contributor), Chang, C. (Contributor), Lai, M. (Contributor), Chen, Y. (Contributor), Liou, J. (Contributor), Teng, C. (Contributor) & Pan, S. (Contributor), Unknown Publisher, May 29 2019
DOI: 10.6084/m9.figshare.8202896.v1, https://springernature.figshare.com/articles/Additional_file_4_of_Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/8202896/1
Dataset
Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chao, M. (Contributor), Chang, L. (Contributor), Tu, H. (Contributor), Chang, C. (Contributor), Lai, M. (Contributor), Chen, Y. (Contributor), Liou, J. (Contributor), Teng, C. (Contributor) & Pan, S. (Contributor), Unknown Publisher, May 29 2019
DOI: 10.6084/m9.figshare.c.4522856.v1, https://doi.org/10.6084%2Fm9.figshare.c.4522856.v1
Dataset
Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms
Mehndiratta, S. (Contributor), Chen, M. (Contributor), Chao, Y. (Contributor), Lee, C. (Contributor), Liou, J. (Contributor), Lai, M. (Contributor) & Lee, H. (Contributor), Unknown Publisher, Jan 1 2020
DOI: 10.6084/m9.figshare.13207104.v1, https://tandf.figshare.com/articles/journal_contribution/Effect_of_3-subsitution_of_quinolinehydroxamic_acids_on_selectivity_of_histone_deacetylase_isoforms/13207104/1
Dataset