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Research Output

  • 1799 Citations
  • 24 h-Index
  • 50 Article
  • 2 Book
  • 1 Comment/debate
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Article
2020

In vitro and in vivo evaluation of the neuroprotective activity of Uncaria hirsuta Haviland

Lin, C. M., Lin, Y. T., Lee, T. L., Imtiyaz, Z., Hou, W. C. & Lee, M. H., Jan 2020, In : Journal of Food and Drug Analysis. 28, 1, p. 147-158 12 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2019

Isolated compounds from turpinia formosana nakai induce ossification

Imtiyaz, Z., Wang, Y. F., Lin, Y. T., Liu, H. K. & Lee, M. H., Jul 1 2019, In : International Journal of Molecular Sciences. 20, 13, 3119.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Liposomal irinotecan for treatment of colorectal cancer in a preclinical model

Huang, J. R., Lee, M. H., Li, W. S. & Wu, H. C., Mar 1 2019, In : Cancers. 11, 3, 281.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Genomic Alterations of Extrectra Cellular Genes as Diagnosis Markers for Head and Neck Squamous Cell Carcinoma

Yang, C-H., Lin, R-D., Lee, M-H., Tsai, M-H. & Su, L-J., 2018, In : International Journal of Head and Neck Science. 2, 1, p. 21-24 4 p.

Research output: Contribution to journalArticle

2017
6 Citations (Scopus)
2016

An in vivo molecular response analysis of colorectal cancer treated with Astragalus membranaceus extract

Tseng, A., Yang, C. H., Chen, C. H., Chen, C. H., Hsu, S. L., Lee, M. H., Lee, H. C. & Su, L. J., Feb 1 2016, In : Oncology Reports. 35, 2, p. 659-668 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2015
15 Citations (Scopus)

New whitening constituents from taiwan-native Pyracantha koidzumii: Structures and tyrosinase inhibitory analysis in human epidermalmelanocytes

Lin, R. D., Chen, M. C., Liu, Y. L., Lin, Y. T., Lu, M. K., Hsu, F-L. & Lee, M. H., Dec 2 2015, In : International Journal of Molecular Sciences. 16, 12, p. 28598-28613 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Pb2+ induces gastrin gene expression by extracellular signal-regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells

Chan, C. P., Tsai, Y. T., Chen, Y. L., Hsu, Y. W., Tseng, J. T., Chuang, H. Y., Shiurba, R., Lee, M. H., Wang, J. Y. & Chang, W. C., Feb 1 2015, In : Environmental Toxicology. 30, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2014

Stimulation of osteogenic activity in human osteoblast cells by edible Uraria crinita

Mao, Y. W., Lin, R. D., Hung, H. C. & Lee, M. H., Jun 18 2014, In : Journal of Agricultural and Food Chemistry. 62, 24, p. 5581-5588 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013

Chemical and pharmacological investigation of micropropagated Hygrophila pogonocalyx produced from leaf explants

Ho, C. W., Lin, R. D., Li, Z-H., Lin, C. H., Wen, C. L., Tseng, Y. T. & Lee, M. H., 2013, In : Botanical Studies. 54, 1, 51.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization

Guo, Y. C., Chang, C. M., Hsu, W. L., Chiu, S. J., Tsai, Y. T., Chou, Y. H., Hou, M. F., Wang, J. Y., Lee, M. H., Tsai, K. L. & Chang, W. C., Jun 2013, In : Molecules. 18, 6, p. 6584-6596 13 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2012

Chemical and biological evaluation of nephrocizin in protecting nerve growth factor-differentiated PC12 cells by 6-hydroxydopamine-induced neurotoxicity

Lin, Y. P., Chen, T. Y., Tseng, H. W., Lee, M. H. & Chen, S. T., Dec 2012, In : Phytochemistry. 84, p. 102-115 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
20 Citations (Scopus)
2011

Anti-inflammatory and free radial scavenging activities of the constituents isolated from machilus zuihoensis

Mao, Y. W., Tseng, H. W., Liang, W. L., Chen, I. S., Chen, S. T. & Lee, M. H., Nov 2011, In : Molecules. 16, 11, p. 9451-9466 16 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The immuno-regulatory effects of Schisandra chinensis and its constituents on human monocytic leukemia cells

Lin, R. D., Mao, Y. W., Leu, S. J., Huang, C. Y. & Lee, M. H., Jun 2011, In : Molecules. 16, 6, p. 4836-4849 14 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2010

Neurocytoprotective effects of the bioactive constituents of Pueraria thomsonii in 6-hydroxydopamine (6-OHDA)-treated nerve growth factor (NGF)-differentiated PC12 cells

Lin, C. M., Lin, R. D., Chen, S. T., Lin, Y. P., Chiu, W. T., Lin, J. W., Hsu, F. L. & Lee, M. H., Dec 2010, In : Phytochemistry. 71, 17-18, p. 2147-2156 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Regulation of cytokine production by treating with Chinese tonic herbs in human peripheral blood mononuclear and human acute monocytic leukemia cells

Shin, H. Y., Kuo, Y. C., Hsu, F-L., Mao, Y. W. & Lee, M. H., Dec 2010, In : Journal of Food and Drug Analysis. 18, 6, p. 414-424 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2009

Active constituents from Sophora japonica exhibiting cellular tyrosinase inhibition in human epidermal melanocytes

Lo, Y. H., Lin, R. D., Lin, Y. P., Liu, Y. L. & Lee, M. H., Jul 30 2009, In : Journal of Ethnopharmacology. 124, 3, p. 625-629 5 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Neural cell protective compounds isolated from Phoenix hanceana var. formosana

Lin, Y. P., Chen, T. Y., Tseng, H. W., Lee, M. H. & Chen, S. T., Jun 2009, In : Phytochemistry. 70, 9, p. 1173-1181 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Taiwanese native plants inhibit matrix metalloproteinase-9 activity after ultraviolet B irradiation

Lee, Y. L., Lee, M. H., Chang, H. J., Huang, P. Y., Huang, I. J., Cheng, K. T. & Leu, S. J., Mar 2009, In : Molecules. 14, 3, p. 1062-1071 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2008

Anemonin is a natural bioactive compound that can regulate tyrosinase-related proteins and mRNA in human melanocytes

Huang, Y. H., Lee, T. H., Chan, K. J., Hsu, F. L., Wu, Y. C. & Lee, M. H., Feb 2008, In : Journal of Dermatological Science. 49, 2, p. 115-123 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The effect of Chinese herbal medicines on TNF-α induced matrix metalloproteinase-1, -9 activities and interleukin-8 secretion

Lee, M. H., Yang, Y. Y., Tsai, Y-H., Lee, Y. L., Huang, P. Y., Huang, I. J., Cheng, K. T. & Leu, S. J., Oct 2008, In : Botanical Studies. 49, 4, p. 301-309 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
20 Citations (Scopus)
2007

Constituents from the Formosan apple reduce tyrosinase activity in human epidermal melanocytes

Lin, Y. P., Hsu, F-L., Chen, C. S., Chern, J. W. & Lee, M. H., Apr 2007, In : Phytochemistry. 68, 8, p. 1189-1199 11 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Corrigendum to "Constituents from the Formosan apple reduce tyrosinase activity in human epidermal melanocytes" [Phytochemistry 68 (2007) 1189-1199] (DOI: 10.1016/j.phytochem.2007.02.001)

Lin, Y. P., Hsu, F. L., Chen, C. S., Chern, J. W. & Lee, M. H., Oct 2007, In : Phytochemistry. 68, 19, p. 2498 1 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2006

Antioxidant and heme oxygenase-1 (HO-1)-induced effects of selected Taiwanese plants

Lee, M. H., Jiang, C. B., Juan, S. H., Lin, R. D. & Hou, W. C., Feb 2006, In : Fitoterapia. 77, 2, p. 109-115 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Bioactive constituents of Spatholobus suberectus in regulating tyrosinase-related proteins and mRNA in HEMn cells

Lee, M. H., Lin, Y. P., Hsu, F-L., Zhan, G. R. & Yen, K. Y., Jun 2006, In : Phytochemistry. 67, 12, p. 1262-1270 9 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

Cosmetic applications of selected traditional Chinese herbal medicines

Wang, K-H., Lin, R. D., Hsu, F-L., Huang, Y-H., Chang, H. C., Huang, C. Y. & Lee, M-H., Jul 19 2006, In : Journal of Ethnopharmacology. 106, 3, p. 353-359 7 p.

Research output: Contribution to journalArticle

144 Citations (Scopus)

Natural products of cosmetics: Analysis of extracts of plants endemic to Taiwan for the presence of tyrosinase-inhibitory, melanin-reducing, and free radical scavenging activities

Jiang, C. B., Chang, M. J., Wen, C. L., Lin, Y. P., Hsu, F-L. & Lee, M. H., Dec 2006, In : Journal of Food and Drug Analysis. 14, 4, p. 346-352 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Phenolic constituents of Malus doumeri var. formosana in the field of skin care

Leu, S. J., Lin, Y. P., Lin, R. D., Wen, C. L., Cheng, K. T., Hsu, F-L. & Lee, M. H., Apr 2006, In : Biological and Pharmaceutical Bulletin. 29, 4, p. 740-745 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2005
41 Citations (Scopus)

Monoamine oxidase B (MAO-B) inhibition by active principles from Uncaria rhynchophylla

Hou, W. C., Lin, R. D., Chen, C. T. & Lee, M. H., Aug 22 2005, In : Journal of Ethnopharmacology. 100, 1-2, p. 216-220 5 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

The phenolic constituent and free radical scavenging activities of Gynura formosona Kiamnra

Hou, W. C., Lin, R. D., Li, Z-H., Huang, Y. H., Hsu, F-L. & Lee, M. H., Mar 2005, In : Journal of the Science of Food and Agriculture. 85, 4, p. 615-621 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
2003

Free radical-scavenging activity of Taiwanese native plants

Hou, W. C., Lin, R. D., Cheng, K. T., Hung, Y. T., Cho, C. H., Chen, C. H., Hwang, S. Y. & Lee, M. H., Mar 2003, In : Phytomedicine. 10, 2-3, p. 170-175 6 p.

Research output: Contribution to journalArticle

138 Citations (Scopus)

Inhibition of monoamine oxidase B (MAO-B) by Chinese herbal medicines

Lin, R. D., Hou, W. C., Yen, K. Y. & Lee, M. H., Nov 2003, In : Phytomedicine. 10, 8, p. 650-656 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
16 Citations (Scopus)

Patatin, the tuber storage protein of potato (Solanum tuberosum L.), exhibits antioxidant activity in vitro

Liu, Y. W., Han, C. H., Lee, M. H., Hsu, F-L. & Hou, W. C., Jul 16 2003, In : Journal of Agricultural and Food Chemistry. 51, 15, p. 4389-4393 5 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

The mucilage of yam (Dioscorea batatas Decne) tuber exhibited angiotensin converting enzyme inhibitory activities

Lee, M. H., Lin, Y. S., Lin, Y. H., Hsu, F-L. & Hou, W. C., Oct 2003, In : Botanical Bulletin of Academia Sinica. 44, 4, p. 267-273 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2002

Activity staining of plasma amine oxidase after polyacrylamide gel electrophoresis and its application to natural inhibiro screening

Lee, M. H., Chuang, M. T. & Hou, W. C., Aug 2002, In : Electrophoresis. 23, 15, p. 2369-2372 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
87 Citations (Scopus)

Yam (Dioscorea batatas) tuber mucilage exhibited antioxidant activities in vitro

Hou, W. C., Hsu, F-L. & Lee, M. H., Dec 1 2002, In : Planta Medica. 68, 12, p. 1072-1076 5 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)
2001

Activity staining of isocitrate lyase after electrophoresis on either native or sodium dodecyl sulfate polyacrylamide gels

Hou, W. C., Chen, H. J., Lin, Y. H., Chen, Y. C., Yang, L-L. & Lee, M. H., 2001, In : Electrophoresis. 22, 13, p. 2653-2655 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Antioxidant activities of dioscorin, the storage protein of yam (Dioscorea batatas Decne) tuber

Hou, W. C., Lee, M. H., Chen, H. J., Liang, W. L., Han, C. H., Liu, Y. W. & Lin, Y. H., 2001, In : Journal of Agricultural and Food Chemistry. 49, 10, p. 4956-4960 5 p.

Research output: Contribution to journalArticle

155 Citations (Scopus)
73 Citations (Scopus)

Monoamine oxidase B and free radical scavenging activities of natural flavonoids in Melastoma candidum D. Don

Lee, M. H., Lin, R. D., Shen, L. Y., Yang, L-L., Yen, K. Y. & Hou, W. C., 2001, In : Journal of Agricultural and Food Chemistry. 49, 11, p. 5551-5555 5 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
2000

EBV DNA polymerase inhibition of tannins from Eugenia uniflora

Lee, M. H., Chiou, J. F., Yen, K. Y. & Yang, L-L., Jun 30 2000, In : Cancer Letters. 154, 2, p. 131-136 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
1999

Pharmacokinetic study of paeoniflorin in mice after oral administration of Paeoniae radix extract

Chen, L. C., Lee, M. H., Chou, M. H., Lin, M. F. & Yang, L-L., Nov 26 1999, In : Journal of Chromatography B: Biomedical Sciences and Applications. 735, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
1997

Two macrocyclic hydrolysable tannin dimers from Eugenia uniflora

Lee, M. H., Nishimoto, S., Yang, L-L., Yen, K. Y., Hatano, T., Yoshida, T. & Okuda, T., Apr 1997, In : Phytochemistry. 44, 7, p. 1343-1349 7 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)