• 4478 Citations
  • 26 h-Index
1988 …2020
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Research Output 1988 2019

  • 4478 Citations
  • 26 h-Index
  • 47 Article
  • 1 Letter
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Article
2019
1 Citation (Scopus)

IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling

Pidugu, V. K., Wu, M. M., Yen, A. H., Pidugu, H. B., Chang, K. W., Liu, C. J. & Lee, T. C., Apr 25 2019, In : Oncogene. 38, 17, p. 3232-3247 16 p.

Research output: Contribution to journalArticle

Recycling
Squamous Cell Carcinoma
Neoplasm Metastasis
Neoplasms
Epithelial-Mesenchymal Transition
2017
7 Citations (Scopus)
Arsenic
Taiwan
Chronic Renal Insufficiency
Drinking Water
Prospective Studies
4 Citations (Scopus)

Promoter hypermethylation of LGALS4 correlates with poor prognosis in patients with urothelial carcinoma

Wu, M. M., Li, C. F., Lin, L. F., Wang, A. S. S., Pu, Y. S., Wang, H. H., Mar, A. C., Chen, C. J. & Lee, T. C., Jan 1 2017, In : Oncotarget. 8, 14, p. 23787-23802 16 p.

Research output: Contribution to journalArticle

Galectin 4
Carcinoma
Methylation
Neoplasms
Gene Expression
2016
6 Citations (Scopus)

Cumulative arsenic exposure is associated with fungal infections: Two cohort studies based on southwestern and northeastern basins in Taiwan

Hsu, L. I., Cheng, Y. W., Chen, C. J., Wu, M-M., Hsu, K. H., Chiou, H. Y. & Lee, C. H., Nov 1 2016, In : Environment International. 96, p. 173-179 7 p.

Research output: Contribution to journalArticle

arsenic
basin
infection
exposure
diabetes
4 Citations (Scopus)

Effect of heme oxygenase-1 gene promoter polymorphism on cancer risk by histological subtype: A prospective study in arseniasis-endemic areas in Taiwan

Wu, M. M., Lee, C. H., Hsu, L. I., Cheng, W. F., Lee, T. C., Wang, Y. H., Chiou, H. Y. & Chen, C. J., Apr 15 2016, In : International Journal of Cancer. 138, 8, p. 1875-1886 12 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Taiwan
Prospective Studies
Arsenic
Genes
3 Citations (Scopus)

Effects of Arsenic in Drinking Water on Risk of Hepatitis or Cirrhosis in Persons With and Without Chronic Viral Hepatitis

Hsu, L. I., Wang, Y. H., Hsieh, F. I., Yang, T. Y., Wen-Juei Jeng, R., Liu, C. T., Chen, C. L., Hsu, K. H., Chiou, H. Y., Wu, M-M. & Chen, C. J., 2016, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Arsenic
Chronic Hepatitis
Drinking Water
Hepatitis
Fibrosis
2015
18 Citations (Scopus)

Association of environmental arsenic exposure, genetic polymorphisms of susceptible genes, and skin cancers in Taiwan

Hsu, L. I., Wu, M. M., Wang, Y. H., Lee, C. Y., Yang, T. Y., Hsiao, B. Y. & Chen, C. J., 2015, In : BioMed Research International. 2015, 892579.

Research output: Contribution to journalArticle

Environmental Exposure
Arsenic
Skin Neoplasms
Genetic Polymorphisms
Polymorphism
2014
14 Citations (Scopus)

A prospective study of gynecological cancer risk in relation to adiposity factors: Cumulative incidence and association with plasma adipokine levels

Wu, M. M., Chen, H. C., Chen, C. L., You, S. L., Cheng, W. F., Chen, C. A., Lee, T. C. & Chen, C. J., Aug 12 2014, In : PLoS One. 9, 8, e104630.

Research output: Contribution to journalArticle

adipokines
Adipokines
Adiposity
adiposity
Uterine Neoplasms
18 Citations (Scopus)

Comparison of genome-wide DNA methylation in urothelial carcinomas of patients with and without arsenic exposure

Yang, T. Y., Hsu, L. I., Chiu, A. W., Pu, Y. S., Wang, S. H., Liao, Y. T., Wu, M. M., Wang, Y. H., Chang, C. H., Lee, T. C. & Chen, C. J., Jan 1 2014, In : Environmental Research. 128, p. 57-63 7 p.

Research output: Contribution to journalArticle

methylation
Arsenic
DNA Methylation
arsenic
Methylation
14 Citations (Scopus)

Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation

Wang, H. H., Wu, M. M., Chan, M. W. Y., Pu, Y. S., Chen, C. J. & Lee, T. C., 2014, In : Archives of Toxicology. 88, 8, p. 1549-1559 11 p.

Research output: Contribution to journalArticle

Lipocalins
Arsenic
Methylation
decitabine
Gene expression
2013
27 Citations (Scopus)

Comparing the joint effect of arsenic exposure, cigarette smoking and risk genotypes of vascular endothelial growth factor on upper urinary tract urothelial carcinoma and bladder cancer

Wang, Y. H., Yeh, S. D., Wu, M. M., Liu, C. T., Shen, C. H., Shen, K. H., Pu, Y. S., Hsu, L. I., Chiou, H. Y. & Chen, C. J., Nov 15 2013, In : Journal of Hazardous Materials. 262, p. 1139-1146 8 p.

Research output: Contribution to journalArticle

Arsenic
smoking
Urinary Tract
Urinary Bladder Neoplasms
Tobacco Products
8 Citations (Scopus)

Epigenetic silencing of BLU through interfering apoptosis results in chemoresistance and poor prognosis of ovarian serous carcinoma patients

Chiang, Y. C., Chang, M. C., Chen, P. J., Wu, M. M., Hsieh, C-Y., Cheng, W. F. & Chen, C. A., Apr 2013, In : Endocrine-Related Cancer. 20, 2, p. 213-227 15 p.

Research output: Contribution to journalArticle

Epigenomics
Methylation
Apoptosis
Carcinoma
Ovarian Neoplasms
10 Citations (Scopus)

Lifetime risk of urothelial carcinoma and lung cancer in the arseniasis-endemic area of Northeastern Taiwan

Yang, T. Y., Hsu, L. I., Chen, H. C., Chiou, H. Y., Hsueh, Y. M., Wu, M. M., Chen, C. L., Wang, Y. H., Liao, Y. T. & Chen, C. J., Nov 5 2013, In : Journal of Asian Earth Sciences. 77, p. 332-337 6 p.

Research output: Contribution to journalArticle

cancer
arsenic
drinking water
smoking
exposure
3 Citations (Scopus)

The association of diabetes mellitus with subsequent internal cancers in the arsenic-exposed area of Taiwan

Hsu, L. I., Wang, Y. H., Chiou, H. Y., Wu, M. M., Yang, T. Y., Chen, Y. H., Tseng, C. H. & Chen, C. J., Sep 5 2013, In : Journal of Asian Earth Sciences. 73, p. 452-459 8 p.

Research output: Contribution to journalArticle

diabetes
arsenic
cancer
confidence interval
hazard
34 Citations (Scopus)

Urinary arsenic profiles and the risks of cancer mortality: A population-based 20-year follow-up study in arseniasis-endemic areas in Taiwan

Chung, C. J., Huang, Y. L., Huang, Y. K., Wu, M. M., Chen, S. Y., Hsueh, Y. M. & Chen, C. J., Apr 2013, In : Environmental Research. 122, p. 25-30 6 p.

Research output: Contribution to journalArticle

Arsenic
Taiwan
arsenic
cancer
mortality
29 Citations (Scopus)

Use of arsenic-induced palmoplantar hyperkeratosis and skin cancers to predict risk of subsequent internal malignancy

Hsu, L. I., Chen, G. S., Lee, C. H., Yang, T. Y., Chen, Y. H., Wang, Y. H., Hsueh, Y. M., Chiou, H. Y., Wu, M. M. & Chen, C. J., Feb 2013, In : American Journal of Epidemiology. 177, 3, p. 202-212 11 p.

Research output: Contribution to journalArticle

Arsenic
Skin Neoplasms
Confidence Intervals
Bowen's Disease
Lung Neoplasms
2011
20 Citations (Scopus)
Heme Oxygenase-1
Arsenic
Observation
Blood Pressure
Phenotype
24 Citations (Scopus)

Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of southwestern Taiwan

Hsu, L. I., Chen, W. P., Yang, T. Y., Chen, Y. H., Lo, W. C., Wang, Y. H., Liao, Y. T., Hsueh, Y. M., Chiou, H. Y., Wu, M. M. & Chen, C. J., 2011, In : Journal of Biomedical Science. 18, 1, 51.

Research output: Contribution to journalArticle

Arsenic
Genetic Polymorphisms
Glutathione Transferase
Polymorphism
Taiwan
39 Citations (Scopus)

Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes

Hsieh, Y-C., Lien, L-M., Chung, W. T., Hsieh, F-I., Hsieh, P. F., Wu, M. M., Tseng, H. P., Chiou, H-Y. & Chen, C. J., Aug 2011, In : Environmental Research. 111, 6, p. 804-810 7 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Arsenic
Polymorphism
Metabolism
arsenic
2010
80 Citations (Scopus)

Arsenic in drinking water and risk of urinary tract cancer: A follow-up study from Northeastern Taiwan

Chen, C. L., Chiou, H. Y., Hsu, L. I., Hsueh, Y. M., Wu, M. M., Wang, Y. H. & Chen, C. J., Jan 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 1, p. 101-110 10 p.

Research output: Contribution to journalArticle

Urologic Neoplasms
Arsenic
Taiwan
Drinking Water
Drinking
22 Citations (Scopus)

Arsenic-induced QT dispersion is associated with atherosclerotic diseases and predicts long-term cardiovascular mortality in subjects with previous exposure to arsenic: A 17-year follow-up study

Wang, C. H., Chen, C. L., Hsiao, C. K., Chiang, F. T., Hsu, L. I., Chiou, H. Y., Hsueh, Y. M., Wu, M. M. & Chen, C. J., Mar 2010, In : Cardiovascular Toxicology. 10, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Arsenic Poisoning
A 17
Arsenic
Mortality
Coronary Artery Disease
5 Citations (Scopus)

Association of estrogen receptor ± genotypes/ haplotypes with carotid intima-media thickness in taiwanese women

Wu, M. M., Hsieh, Y. C., Lien, L. M., Chen, W. H., Bai, C. H., Chiu, H. C., Chen, H. H., Chung, W. T., Lee, Y. C., Hsu, C. Y., Lin, H. W. & Chiou, H. Y., Jun 2010, In : Angiology. 61, 3, p. 275-282 8 p.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Estrogen Receptors
Haplotypes
Genotype
Single Nucleotide Polymorphism
24 Citations (Scopus)

GT-repeat polymorphism in the heme oxygenase-1 gene promoter and the risk of carotid atherosclerosis related to arsenic exposure

Wu, M. M., Chiou, H. Y., Lee, T. C., Chen, C. L., Hsu, L. I., Wang, Y. H., Huang, W. L., Hsieh, Y. C., Yang, T. Y., Lee, C. Y., Yip, P. K., Wang, C. H., Hsueh, Y. M. & Chen, C. J., 2010, In : Journal of Biomedical Science. 17, 1, 70.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Carotid Artery Diseases
Arsenic
Polymorphism
Genes
25 Citations (Scopus)
Heme Oxygenase-1
Arsenic
Polymorphism
Taiwan
Genes
70 Citations (Scopus)

Ingested arsenic, characteristics of well water consumption and risk of different histological types of lung cancer in northeastern Taiwan

Chen, C. L., Chiou, H. Y., Hsu, L. I., Hsueh, Y. M., Wu, M. M. & Chen Chien-Jen, C. J., Jul 2010, In : Environmental Research. 110, 5, p. 455-462 8 p.

Research output: Contribution to journalArticle

Arsenic
well water
Taiwan
Drinking
arsenic
2009
30 Citations (Scopus)

Increased risk of QT prolongation associated with atherosclerotic diseases in arseniasis-endemic area in southwestern coast of Taiwan

Wang, C. H., Chen, C. L., Hsiao, C. K., Chiang, F. T., Hsu, L. I., Chiou, H. Y., Hsueh, Y. M., Wu, M. M. & Chen, C. J., Sep 15 2009, In : Toxicology and Applied Pharmacology. 239, 3, p. 320-324 5 p.

Research output: Contribution to journalArticle

Arsenic
Taiwan
Coastal zones
Myocardial Ischemia
Carotid Artery Diseases
2008
106 Citations (Scopus)

Arsenic exposure, urinary arsenic speciation, and the incidence of urothelial carcinoma: A twelve-year follow-up study

Huang, Y. K., Huang, Y. L., Hsueh, Y. M., Yang, M. H., Wu, M. M., Chen, S. Y., Hsu, L. I. & Chen, C. J., Oct 2008, In : Cancer Causes and Control. 19, 8, p. 829-839 11 p.

Research output: Contribution to journalArticle

Arsenic
Carcinoma
Incidence
Taiwan
Cohort Studies
2007
159 Citations (Scopus)

A review of the epidemiologic literature on the role of environmental arsenic exposure and cardiovascular diseases

Wang, C. H., Hsiao, C. K., Chen, C. L., Hsu, L. I., Chiou, H. Y., Chen, S. Y., Hsueh, Y. M., Wu, M. M. & Chen, C. J., Aug 1 2007, In : Toxicology and Applied Pharmacology. 222, 3, p. 315-326 12 p.

Research output: Contribution to journalArticle

Environmental Exposure
Arsenic
Arsenic Poisoning
Cardiovascular Diseases
Mortality
117 Citations (Scopus)

Arsenic and diabetes and hypertension in human populations: A review

Chen, C. J., Wang, S. L., Chiou, J. M., Tseng, C. H., Chiou, H. Y., Hsueh, Y. M., Chen, S. Y., Wu, M. M. & Lai, M. S., Aug 1 2007, In : Toxicology and Applied Pharmacology. 222, 3, p. 298-304 7 p.

Research output: Contribution to journalArticle

Arsenic
Medical problems
Hypertension
Population
Drinking Water
45 Citations (Scopus)

Effects of arsenic exposure and genetic polymorphisms of p53, glutathione S-transferase M1, T1, and P1 on the risk of carotid atherosclerosis in Taiwan

Wang, Y-H., Wu, M. M., Hong, C. T., Lien, L-M., Hsieh, Y-C., Tseng, H. P., Chang, S. F., Su, C. L., Chiou, H-Y. & Chen, C. J., Jun 2007, In : Atherosclerosis. 192, 2, p. 305-312 8 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Arsenic
Genetic Polymorphisms
Taiwan
Genotype
2006
34 Citations (Scopus)

Association between chronic exposure to arsenic and slow nerve conduction velocity among adolescents in Taiwan

Tseng, H. P., Wang, Y. H., Wu, M. M., The, H. W., Chiou, H. Y. & Chen, C. J., Jun 2006, In : Journal of Health, Population and Nutrition. 24, 2, p. 182-189 8 p.

Research output: Contribution to journalArticle

Neural Conduction
Arsenic
chronic exposure
arsenic
Taiwan
54 Citations (Scopus)

Effect of plasma homocysteine level and urinary monomethylarsonic acid on the risk of arsenic-associated carotid atherosclerosis

Wu, M. M., Chiou, H. Y., Hsueh, Y. M., Hong, C. T., Su, C. L., Chang, S. F., Huang, W. L., Wang, H. T., Wang, Y. H., Hsieh, Y. C. & Chen, C. J., Oct 1 2006, In : Toxicology and Applied Pharmacology. 216, 1, p. 168-175 8 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Arsenic
Homocysteine
Plasmas
Atherosclerosis
2005
157 Citations (Scopus)

Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan

Chen, C. J., Hsu, L. I., Wang, C. H., Shih, W. L., Hsu, Y. H., Tseng, M. P., Lin, Y. C., Chou, W. L., Chen, C. Y., Lee, C. Y., Wang, L. H., Cheng, Y. C., Chen, C. L., Chen, S. Y., Wang, Y. H., Hsueh, Y. M., Chiou, H. Y. & Wu, M. M., Aug 15 2005, In : Toxicology and Applied Pharmacology. 206, 2, p. 198-206 9 p.

Research output: Contribution to journalArticle

Health hazards
Arsenic
Biomarkers
Taiwan
Health
2004
186 Citations (Scopus)

Ingested arsenic, cigarette smoking, and lung cancer risk: A follow-up study in arseniasis-endemic areas in Taiwan

Chen, C. L., Hsu, L. I., Chiou, H. Y., Hsueh, Y. M., Chen, S. Y., Wu, M. M. & Chen, C. J., Dec 22 2004, In : Journal of the American Medical Association. 292, 24, p. 2984-2990 7 p.

Research output: Contribution to journalArticle

Arsenic
Taiwan
Lung Neoplasms
Smoking
Tobacco Products
2003
162 Citations (Scopus)

Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects

Wu, M. M., Chiou, H. Y., Ho, I. C., Chen, C. J. & Lee, T. C., Aug 1 2003, In : Environmental Health Perspectives. 111, 11, p. 1429-1438 10 p.

Research output: Contribution to journalArticle

Lymphocytes
Arsenic
Gene expression
gene expression
arsenic
2002
195 Citations (Scopus)

Biological gradient between long-term arsenic exposure and carotid atherosclerosis

Wang, C. H., Jeng, J. S., Yip, P. K., Chen, C. L., Hsu, L. I., Hsueh, Y. M., Chiou, H. Y., Wu, M-M. & Chen, C. J., Apr 16 2002, In : Circulation. 105, 15, p. 1804-1809 6 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Arsenic
Water Wells
Water
Alcohol Drinking
2001
164 Citations (Scopus)

Association of blood arsenic levels with increased reactive oxidants and decreased antioxidant capacity in a human population of Northeastern Taiwan

Wu, M. M., Chiou, H. Y., Wang, T. W., Hsueh, Y. M., Wang, I. H., Chen, C. J. & Lee, T. C., 2001, In : Environmental Health Perspectives. 109, 10, p. 1011-1017 7 p.

Research output: Contribution to journalArticle

Arsenic
Taiwan
Oxidants
oxidant
antioxidant
2000
326 Citations (Scopus)

Risk of internal cancers from arsenic in drinking water

Morales, K. H., Ryan, L. M., Kuo, T. L., Wu, M. M. & Chen, C. J., 2000, In : Environmental Health Perspectives. 108, 7, p. 655-661 7 p.

Research output: Contribution to journalArticle

Arsenic
Drinking Water
arsenic
cancer
drinking water
1999

蘭陽盆地現在仍飲用含砷井水居民砷暴露及周邊淋巴球姊妹子染色體交換頻數之相關研究

Chiou, H-Y., 簡伊琇, Yeh, C-Y., 吳美滿, 王以潔, Hsueh, Y-M., 李德章 & Chen, C. J., Dec 1999, In : Taiwan Journal of Public Health. 18, 6a, p. 116-123 8 p.

Research output: Contribution to journalArticle

1994
267 Citations (Scopus)

Ingested inorganic arsenic and prevalence of diabetes mellitus

Lai, M. S., Hsueh, Y-M., Chen, C. J., Shyu, M. P., Chen, S. Y., Kuo, T. L., Wu, M. M. & Tai, T-Y., Mar 1 1994, In : American Journal of Epidemiology. 139, 5, p. 484-492 9 p.

Research output: Contribution to journalArticle

Arsenic
Diabetes Mellitus
Taiwan
Body Mass Index
Water Wells
1992

1979及1989兩年台灣地區十大死因之潛在生命損失與累積死亡率之比較

Translated title of the contribution: Comparison of Potential Life Lost and Cumulative Mortality Rates for 10 Leading Causes of Death in 1979 and 1989 of the Taiwan AreaLin, M-R., Wu, M. M. & Wang, J. D., 1992, In : 中華民國公共衛生學會雜誌. 11, 2, p. 140-149 10 p.

Research output: Contribution to journalArticle

cause of death
mortality
accident
comparison
cancer
616 Citations (Scopus)

Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water

Chen, C. J., Chen, C. W., Wu, M. M. & Kuo, T. L., 1992, In : British Journal of Cancer. 66, 5, p. 888-892 5 p.

Research output: Contribution to journalArticle

Arsenic
Drinking Water
Kidney Neoplasms
Urinary Bladder
Kidney
23 Citations (Scopus)

Relationship between fatty liver, alanine aminotransferase, HBsAg and hepatitis C virus

CHANG, W. Y., CHEN, C. J., LU, S. N., YOU, S. L., CHUANG, W. L., CHEN, S. C., SU, W. P., WANG, L. Y., HSIEH, M. Y., WU, M. M. & TAI, T. Y., Jan 1 1992, In : Journal of Gastroenterology and Hepatology. 7, 5, p. 455-458 4 p.

Research output: Contribution to journalArticle

Fatty Liver
Hepatitis B Surface Antigens
Alanine Transaminase
Hepacivirus
Hepatitis C Antibodies
1990
67 Citations (Scopus)

Risk factors for gallstones among Chinese in Taiwan: A community sonographic survey

Lu, S. N., Chang, W. Y., Wang, L. Y., Hsieh, M. Y., Chuang, W. L., Chen, S. C., Su, W. P., Tai, T. Y., Wu, M. M. & Chen, C. J., Jan 1 1990, In : Journal of Clinical Gastroenterology. 12, 5, p. 542-546 5 p.

Research output: Contribution to journalArticle

Gallstones
Taiwan
Diabetes Mellitus
Hyperlipidemias
Odds Ratio
1989
537 Citations (Scopus)

Dose-response relation between arsenic concentration in well water and mortality from cancers and vascular diseases

Wu, M. M., Kuo, T. L., Hwang, Y. H. & Chen, C. J., Dec 1989, In : American Journal of Epidemiology. 130, 6, p. 1123-1132 10 p.

Research output: Contribution to journalArticle

Arsenic
Vascular Diseases
Mortality
Water
Neoplasms
138 Citations (Scopus)

Hepatitis B virus marker in Chinese twins

Lin, T. M., Chen, C. J., Wu, M. M., Yang, C. S., Chen, J. S., Lin, C. C., Kwang, T. Y., Hsu, S. T., Lin, S. Y. & Hsu, L. C., Jan 1 1989, In : Anticancer Research. 9, 3, p. 737-741 5 p.

Research output: Contribution to journalArticle

Monozygotic Twins
Dizygotic Twins
Hepatitis B virus
Virus Diseases
Hepatitis B e Antigens
1988
245 Citations (Scopus)

Atherogenicity and carcinogenicity of high-arsenic artesian well water. Multiple risk factors and related malignant neoplasms of blackfoot disease

Chen, C. J., Wu, M. M., Lee, S. S., Wang, J. D., Cheng, S. H. & Wu, H. Y., Jan 1 1988, In : Arteriosclerosis. 8, 5, p. 452-460 9 p.

Research output: Contribution to journalArticle

Water Wells
Arsenic
Water
Neoplasms
Endemic Diseases