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Research Output 2009 2019

  • 830 Citations
  • 13 h-Index
  • 27 Article
  • 2 Comment/debate
2009
8 Citations (Scopus)

Concomitant upregulation of matrix metalloproteinase-2 in lesions and circulating plasma of oral lichen planus

Tsai, L. L., Yang, S. F., Tsai, C. H., Chou, M. Y. & Chang, Y. C., Mar 2009, In : Journal of Dental Sciences. 4, 1, p. 7-12 6 p.

Research output: Contribution to journalArticle

Oral Lichen Planus
Matrix Metalloproteinase 2
Up-Regulation
Matrix Metalloproteinases
Serum
2011
102 Citations (Scopus)

Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer

Chang, C. J., Hsu, C. C., Chang, C. H., Tsai, L-L., Chang, Y. C., Lu, S. W., Yu, C. H., Huang, H. S., Wang, J. J., Tsai, C. H., Chou, M. Y., Yu, C. C. & Hu, F. W., Oct 2011, In : Oncology Reports. 26, 4, p. 1003-1010 8 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Mouth Neoplasms
Squamous Cell Carcinoma
Aptitude
Snails
115 Citations (Scopus)

Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma

Tsai, L. L., Yu, C. C., Chang, Y. C., Yu, C. H. & Chou, M. Y., Sep 2011, In : Journal of Oral Pathology and Medicine. 40, 8, p. 621-628 8 p.

Research output: Contribution to journalArticle

Cisplatin
Squamous Cell Carcinoma
Serial Passage
Neoplasms
Neoplastic Stem Cells
88 Citations (Scopus)

MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation

Yu, C. C., Chen, Y. W., Chiou, G. Y., Tsai, L. L., Huang, P. I., Chang, C. Y., Tseng, L. M., Chiou, S. H., Yen, S. H., Chou, M. Y., Chu, P. Y. & Lo, W. L., Mar 2011, In : Oral Oncology. 47, 3, p. 202-210 9 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
MicroRNAs
Neoplastic Stem Cells
Neoplasms
2012
5 Citations (Scopus)

Enhanced cisplatin resistance in oral-cancer stem-like cells is correlated with upregulation of excision-repair cross-complementation group 1

Tsai, L-L., Yu, C. C., Lo, J. F., Sung, W. W., Lee, H., Chen, S. L. & Chou, M. Y., Jun 2012, In : Journal of Dental Sciences. 7, 2, p. 111-117 7 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Mouth Neoplasms
DNA Repair
Cisplatin
Up-Regulation
61 Citations (Scopus)

Impairment of tumor-initiating stem-like property and reversal of epithelial-mesenchymal transdifferentiation in head and neck cancer by resveratrol treatment

Hu, F. W., Tsai, L. L., Yu, C. H., Chen, P. N., Chou, M. Y. & Yu, C. C., Aug 2012, In : Molecular Nutrition and Food Research. 56, 8, p. 1247-1258 12 p.

Research output: Contribution to journalArticle

resveratrol
Head and Neck Neoplasms
Neoplastic Stem Cells
Epithelial-Mesenchymal Transition
neoplasms
79 Citations (Scopus)

Resveratrol suppresses tumorigenicity and enhances radiosensitivity in primary glioblastoma tumor initiating cells by inhibiting the STAT3 axis

Yang, Y. P., Chang, Y. L., Huang, P. I., Chiou, G. Y., Tseng, L. M., Chiou, S. H., Chen, M. H., Chen, M. T., Shih, Y. H., Chang, C. H., Hsu, C. C., Ma, H. I., Wang, C. T., Tsai, L-L., Yu, C. C. & Chang, C. J., Mar 2012, In : Journal of Cellular Physiology. 227, 3, p. 976-993 18 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Radiation Tolerance
Glioblastoma
Tumors
Small Interfering RNA
9 Citations (Scopus)

β-catenin expression in areca quid chewing-associated oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells

Lee, S. S., Tsai, C. H., Tsai, L. L., Chou, M. C., Chou, M. Y. & Chang, Y. C., Apr 2012, In : Journal of the Formosan Medical Association. 111, 4, p. 194-200 7 p.

Research output: Contribution to journalArticle

Arecoline
Areca
Catenins
Mastication
Squamous Cell Carcinoma
2013
53 Citations (Scopus)

Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer

Chu, P. Y., Hu, F. W., Yu, C. C., Tsai, L. L., Yu, C. H., Wu, B. C., Chen, Y. W., Huang, P. I. & Lo, W. L., Jan 2013, In : Oral Oncology. 49, 1, p. 34-41 8 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Head and Neck Neoplasms
Transcription Factors
Neoplasms
Neoplastic Stem Cells
95 Citations (Scopus)

MiR145 targets the SOX9/ADAM17 axis to inhibit tumor-initiating cells and IL-6-mediated paracrine effects in head and neck cancer

Yu, C. C., Tsai, L. L., Wang, M. L., Yu, C. H., Lo, W. L., Chang, Y. C., Chiou, G. Y., Chou, M. Y. & Chiou, S. H., Jun 1 2013, In : Cancer Research. 73, 11, p. 3425-3440 16 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Head and Neck Neoplasms
Interleukin-6
Curcumin
Interleukin-6 Receptors
32 Citations (Scopus)

Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer

Chang, W. W., Hu, F. W., Yu, C. C., Wang, H. H., Feng, H. P., Lan, C., Tsai, L. L. & Chang, Y. C., Mar 2013, In : Head and Neck. 35, 3, p. 413-419 7 p.

Research output: Contribution to journalArticle

Quercetin
Head and Neck Neoplasms
Neoplastic Stem Cells
Neoplasms
Epithelial-Mesenchymal Transition
2014
27 Citations (Scopus)

Concurrent expression of Oct4 and Nanog maintains mesenchymal stem-like property of human dental pulp cells

Huang, C. E., Hu, F. W., Yu, C. H., Tsai, L. L., Lee, T. H., Chou, M. Y. & Yu, C. C., Oct 15 2014, In : International Journal of Molecular Sciences. 15, 10, p. 18623-18639 17 p.

Research output: Contribution to journalArticle

Dental Pulp
stem cells
Stem cells
stems
Pulp
13 Citations (Scopus)

Enhanced Chemosensitivity by Targeting Nanog in Head and Neck Squamous Cell Carcinomas

Huang, C. E., Yu, C. C., Hu, F. W., Chou, M. Y. & Tsai, L. L., Aug 25 2014, In : International Journal of Molecular Sciences. 15, 9, p. 14935-14948 14 p.

Research output: Contribution to journalArticle

cancer
spheroids
Neoplastic Stem Cells
Stem cells
stem cells
17 Citations (Scopus)

Licochalcone A inhibits the migration and invasion of human lung cancer cells via inactivation of the Akt signaling pathway with downregulation of MMP-1/-3 expression

Huang, H. C., Tsai, L. L., Tsai, J. P., Hsieh, S. C., Yang, S. F., Hsueh, J. T. & Hsieh, Y. H., Aug 23 2014, (Accepted/In press) In : Tumor Biology.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Lung Neoplasms
Down-Regulation
Cell Migration Inhibition
Sp1 Transcription Factor
44 Citations (Scopus)

Oct4 mediates tumor initiating properties in oral squamous cell carcinomas through the regulation of epithelial-mesenchymal transition

Tsai, L. L., Hu, F. W., Lee, S. S., Yu, C. H., Yu, C. C. & Chang, Y. C., Jan 27 2014, In : PLoS One. 9, 1, e87207.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
squamous cell carcinoma
Tumors
Squamous Cell Carcinoma
mouth
2015

Erratum: MiR145 Targets the SOX9/ADAM17 axis to inhibit tumor-initiating cells and IL6-mediated paracrine effects in head and neck cancer (Cancer Research (2013) 73 (3425-3440))

Yu, C. C., Tsai, L. L., Wang, M. L., Yu, C. C., Lo, W. L. & Chang, Y. C., Jul 1 2015, In : Cancer Research. 75, 13, 1 p.

Research output: Contribution to journalComment/debate

2016
8 Citations (Scopus)

Treatment of bisphosphonate-related osteonecrosis of the jaw with platelet-rich fibrin

Tsai, L. L., Huang, Y. F. & Chang, Y. C., Jul 1 2016, In : Journal of the Formosan Medical Association. 115, 7, p. 585-586 2 p.

Research output: Contribution to journalComment/debate

Oral Surgical Procedures
Bisphosphonate-Associated Osteonecrosis of the Jaw
Panoramic Radiography
Jaw
Fibrin
2017
17 Citations (Scopus)

Bacterial alterations in salivary microbiota and their association in oral cancer

Lee, W. H., Chen, H. M., Yang, S. F., Liang, C., Peng, C. Y., Lin, F. M., Tsai, L. L., Wu, B. C., Hsin, C. H., Chuang, C. Y., Yang, T., Yang, T. L., Ho, S. Y., Chen, W. L., Ueng, K. C., Huang, H. D., Huang, C. N. & Jong, Y. J., Dec 1 2017, In : Scientific Reports. 7, 1, 16540.

Research output: Contribution to journalArticle

Mouth Neoplasms
Microbiota
Neoplasms
Squamous Cell Carcinoma
Peptostreptococcus
8 Citations (Scopus)

DHFR and MDR1 upregulation is associated with chemoresistance in osteosarcoma stem-like cells

Lee, Y. H., Yang, H. W., Yang, L. C., Lu, M. Y., Tsai, L. L., Yang, S. F., Huang, Y. F., Chou, M. Y., Yu, C. C. & Hu, F. W., 2017, In : Oncology Letters. 14, 1, p. 171-179 9 p.

Research output: Contribution to journalArticle

Tetrahydrofolate Dehydrogenase
P-Glycoprotein
Osteosarcoma
Up-Regulation
Stem Cells
19 Citations (Scopus)

Targeting LncRNA HOTAIR suppresses cancer stemness and metastasis in oral carcinomas stem cells through modulation of EMT

Lu, M. Y., Liao, Y. W., Chen, P. Y., Hsieh, P. L., Fang, C. Y., Wu, C. Y., Yen, M. L., Peng, B. Y., Wang, D. P., Cheng, H. C., Wu, C. Z., Shih, Y. H., Wang, D. J., Yu, C. C. & Tsai, L. L., Jan 1 2017, In : Oncotarget. 8, 58, p. 98542-98552 11 p.

Research output: Contribution to journalArticle

Antisense RNA
Epithelial-Mesenchymal Transition
Stem Cells
Neoplasm Metastasis
Carcinoma
2018
6 Citations (Scopus)

Antimetastatic potentials of salvianolic acid A on oral squamous cell carcinoma by targeting MMP-2 and the c-Raf/MEK/ERK pathway

Fang, C. Y., Wu, C. Z., Chen, P. N., Chang, Y. C., Chuang, C. Y., Lai, C. T., Yang, S. F. & Tsai, L. L., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Mitogen-Activated Protein Kinase Kinases
targeting
Squamous Cell Carcinoma
matrix
3 Citations (Scopus)

Butylidenephthalide abrogates the myofibroblasts activation and mesenchymal transdifferentiation in oral submucous fibrosis

Su, T. R., Liao, Y. W., Hsieh, P. L., Tsai, L. L., Fang, C. Y., Lin, T., Lee, Y. H., Harn, H. J. & Yu, C. C., Jun 1 2018, In : Environmental Toxicology. 33, 6, p. 686-694 9 p.

Research output: Contribution to journalArticle

Oral Submucous Fibrosis
Myofibroblasts
snail
collagen
Chemical activation
2 Citations (Scopus)

Chemosensitizing effect of honokiol in oral carcinoma stem cells via regulation of IL-6/Stat3 signaling

Chang, M. T., Lee, S. P., Fang, C. Y., Hsieh, P. L., Liao, Y. W., Lu, M. Y., Tsai, L. L., Yu, C. C. & Liu, C. M., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

Stem cells
cancer
Interleukin-6
Stem Cells
stem
3 Citations (Scopus)

Let-7c restores radiosensitivity and chemosensitivity and impairs stemness in oral cancer cells through inhibiting interleukin-8

Peng, C. Y., Wang, T. Y., Lee, S. S., Hsieh, P. L., Liao, Y. W., Tsai, L. L., Fang, C. Y., Yu, C. C. & Hsieh, C. S., Jan 1 2018, (Accepted/In press) In : Journal of Oral Pathology and Medicine.

Research output: Contribution to journalArticle

Mouth Neoplasms
Radiation Tolerance
Interleukin-8
Neoplastic Stem Cells
Radio
4 Citations (Scopus)

miR-145 mediates the anti-cancer stemness effect of photodynamic therapy with 5-aminolevulinic acid (ALA) in oral cancer cells

Fang, C. Y., Chen, P. Y., Ho, D. C. Y., Tsai, L. L., Hsieh, P. L., Lu, M. Y., Yu, C. C. & Yu, C. H., Aug 1 2018, In : Journal of the Formosan Medical Association. 117, 8, p. 738-742 5 p.

Research output: Contribution to journalArticle

Aminolevulinic Acid
Mouth Neoplasms
Photochemotherapy
MicroRNAs
Neoplastic Stem Cells
4 Citations (Scopus)

Synthesis and Characterization of Polycaprolactone-Based Polyurethanes for the Fabrication of Elastic Guided Bone Regeneration Membrane

Lee, S. Y., Wu, S. C., Chen, H., Tsai, L. L., Tzeng, J. J., Lin, C. H. & Lin, Y. M., Jan 1 2018, In : BioMed Research International. 2018, 3240571.

Research output: Contribution to journalArticle

Bone Regeneration
Polyurethanes
Bone
Membranes
Fabrication
2019
1 Citation (Scopus)
Comorbidity
Aphthous Stomatitis
Peptic Ulcer
Liver Diseases
Sutton disease 2
2 Citations (Scopus)

LncRNA LINC00974 activates TGF-β/Smad signaling to promote oral fibrogenesis

Fang, C. Y., Yu, C. C., Liao, Y. W., Hsieh, P. L., Lu, M. Y., Lin, K. C., Wu, C. Z. & Tsai, L. L., 2019, In : Journal of Oral Pathology and Medicine.

Research output: Contribution to journalArticle

Myofibroblasts
Oral Submucous Fibrosis
Arecoline
Long Noncoding RNA
Collagen Type I
5 Citations (Scopus)

Slug mediates myofibroblastic differentiation to promote fibrogenesis in buccal mucosa

Fang, C. Y., Hsia, S. M., Hsieh, P. L., Liao, Y. W., Peng, C. Y., Wu, C. Z., Lin, K. C., Tsai, L. L. & Yu, C. C., 2019, In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Arecoline
Gastropoda
Mouth Mucosa
Collagen Type I
Myofibroblasts