• 683 Citations
  • 7 h-Index
20082020

Research output per year

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Research Output

  • 683 Citations
  • 7 h-Index
  • 9 Article
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Article
2020

A robust TDP-43 knock-in mouse model of ALS

Huang, S. L., Wu, L. S., Lee, M., Chang, C. W., Cheng, W. C., Fang, Y. S., Chen, Y. R., Cheng, P. L. & Shen, C. K. J., Jan 21 2020, In : Acta neuropathologica communications. 8, 1, 3.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2019

Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons

Wu, L. S., Cheng, W. C., Chen, C. Y., Wu, M. C., Wang, Y. C., Tseng, Y. H., Chuang, T. J. & Shen, C-K., Mar 29 2019, In : Acta neuropathologica communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
2016

Structural analysis of disease-related TDP-43 D169G mutation: Linking enhanced stability and caspase cleavage efficiency to protein accumulation

Chiang, C. H., Grauffel, C., Wu, L. S., Kuo, P. H., Doudeva, L. G., Lim, C., Shen, C. K. J. & Yuan, H. S., Feb 17 2016, In : Scientific Reports. 6, 21581.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)
2014

Curcumin abolishes mutant TDP-43 induced excitability in a motoneuron-like cellular model of ALS

Dong, H., Xu, L., Wu, L., Wang, X., Duan, W., Li, H. & Li, C., Jul 11 2014, In : Neuroscience. 272, p. 141-153 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2013
Open Access
8 Citations (Scopus)
2012
Open Access
92 Citations (Scopus)
2010

TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis

Wu, L. S., Cheng, W., Hou, S. C., Yan, Y. T., Jiang, S. T. & Shen, C. K. J., Jan 1 2010, In : Genesis. 48, 1, p. 56-62 7 p.

Research output: Contribution to journalArticle

185 Citations (Scopus)
2008

TDP-43: an emerging new player in neurodegenerative diseases

Wang, I. F., Wu, L. S. & Shen, C. K. J., Nov 1 2008, In : Trends in Molecular Medicine. 14, 11, p. 479-485 7 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

Wang, I. F., Wu, L. S., Chang, H. Y. & Shen, C. K. J., May 1 2008, In : Journal of Neurochemistry. 105, 3, p. 797-806 10 p.

Research output: Contribution to journalArticle

261 Citations (Scopus)