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Lien-Szu Wu

Research Fellow

 https://orcid.org/0000-0003-0216-882X
  • 673 Citations
  • 7 h-Index
20082019

Research output per year

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Research Output

  • 673 Citations
  • 7 h-Index
  • 8 Article

Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons

Wu, L. S., Cheng, W. C., Chen, C. Y., Wu, M. C., Wang, Y. C., Tseng, Y. H., Chuang, T. J. & Shen, C. K. J., Mar 29 2019, In : Acta neuropathologica communications. 7, 1, 1 p.

Research output: Contribution to journal › Article

Open Access

    • Structural analysis of disease-related TDP-43 D169G mutation: Linking enhanced stability and caspase cleavage efficiency to protein accumulation

    Chiang, C. H., Grauffel, C., Wu, L. S., Kuo, P. H., Doudeva, L. G., Lim, C., Shen, C. K. J. & Yuan, H. S., Feb 17 2016, In : Scientific Reports. 6, 21581.

    Research output: Contribution to journal › Article

    Open Access
    • 26 Citations (Scopus)

    Curcumin abolishes mutant TDP-43 induced excitability in a motoneuron-like cellular model of ALS

    Dong, H., Xu, L., Wu, L., Wang, X., Duan, W., Li, H. & Li, C., Jul 11 2014, In : Neuroscience. 272, p. 141-153 13 p.

    Research output: Contribution to journal › Article

    • 20 Citations (Scopus)

    Similar dose-dependence of motor neuron cell death caused by wild type human TDP-43 and mutants with ALS-associated amino acid substitutions

    Wu, L. S., Cheng, W. C. & Shen, C. K. J., Jun 3 2013, In : Journal of Biomedical Science. 20, 1, 33.

    Research output: Contribution to journal › Article

    Open Access
    • 8 Citations (Scopus)

    Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice

    Wu, L. S., Cheng, W. C. & Shen, C. K. J., Aug 10 2012, In : Journal of Biological Chemistry. 287, 33, p. 27335-27344 10 p.

    Research output: Contribution to journal › Article

    Open Access
    • 91 Citations (Scopus)