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Personal profile


  • 2014 Medical researcher, Division of Gastroenterology and Hepatology, Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare
  • 2004 research assistant, IBMS, Academia Sinica
  • 2001 lecture, School of Nursing, Tzu Chi University


  • 2011 Graduate Institute of Medical Sciences thesis competition prize works, TMU
  • 2010 Memorial Scholarship of Dr. Shin-Chieh Liang, TMU
  • 2005 Scholarship of Rotary Club Taipei Taiwan


  • 2014, Phd (Graduate Institute of Medical Science), Taipei Medical University

Research Interests

  • Cancer molecular biology

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2015 2019

Primase, DNA, polypeptide 1(PRIM1)參與吸菸所誘發乳癌形成機制及臨床轉譯研究(2/3)

Chen, L.


Project: A - Government Institutionb - Ministry of Science and Technology

Primase, DNA, polypeptide 1(PRIM1)參與吸菸所誘發乳癌形成機制及臨床轉譯研究(1/3)

Chen, L.


Project: A - Government Institutionb - Ministry of Science and Technology


Chen, L.


Project: A - Government Institutionb - Ministry of Science and Technology


Chen, L.


Project: B - Project of TMUh - Other (Funded by TMU)

Research Output 2002 2019

  • 844 Citations
  • 16 h-Index
  • 43 Article
  • 1 Review article
2 Citations (Scopus)

DNA primase polypeptide 1 (PRIM1) involves in estrogen-induced breast cancer formation through activation of the G2/M cell cycle checkpoint

Lee, W-H., Chen, L-C., Lee, C-J., Huang, C-C., Ho, Y-S., Yang, P-S., Ho, C-T., Chang, H-L., Lin, I-H., Chang, H-W., Liu, Y-R., Wu, C-H. & Tu, S-H., Feb 1 2019, In : International Journal of Cancer. 144, 3, p. 615-630 16 p.

Research output: Contribution to journalArticle

DNA Primase
G2 Phase Cell Cycle Checkpoints
Breast Neoplasms

Small G protein signalling modulator 2 (SGSM2) is involved in oestrogen receptor-positive breast cancer metastasis through enhancement of migratory cell adhesion via interaction with E-cadherin

Lin, J. H., Lee, W. J., Wu, H. C., Wu, C. H., Chen, L. C., Huang, C. C., Chang, H. L., Cheng, T. C., Chang, H. W., Ho, C. T., Tu, S. H. & Ho, Y. S., Jan 1 2019, In : Cell Adhesion and Migration.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Cell Adhesion
Estrogen Receptors
Breast Neoplasms

Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation

Chen, L. C., Tseng, H. J., Liu, C. Y., Huang, Y. Y., Yen, C. C., Weng, J. R., Lu, Y. L., Hou, W. C., Lin, T. E., Pan, I. H., Huang, K. K., Huang, W. J. & Hsu, K. C., Jul 3 2018, In : Frontiers in Pharmacology. 9, JUL, 708.

Research output: Contribution to journalArticle

Histone Deacetylases
Alzheimer Disease
Nicotinic Receptors
Tobacco Smoke Pollution
1 Citation (Scopus)

Oestrogen receptor-regulated glutathione S-transferase mu 3 expression attenuates hydrogen peroxide-induced cytotoxicity, which confers tamoxifen resistance on breast cancer cells

Lin, J. H., Tu, S. H., Chen, L. C., Huang, C. C., Chang, H. L., Cheng, T. C., Chang, H. W., Wu, C. H., Wu, H. C. & Ho, Y. S., Jan 1 2018, (Accepted/In press) In : Breast Cancer Research and Treatment.

Research output: Contribution to journalArticle

Glutathione Transferase
Estrogen Receptors
Hydrogen Peroxide
Breast Neoplasms