• 1385 Citations
  • 22 h-Index
20082020

Research output per year

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Research Output

  • 1385 Citations
  • 22 h-Index
  • 50 Article
  • 16 Review article
  • 2 Comment/debate
  • 1 Chapter
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Article
2020
1 Citation (Scopus)
1 Citation (Scopus)
2019

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1 Citation (Scopus)

Benzoflavone derivatives as potent antihyperuricemic agents

Singh, J. V., Mal, G., Kaur, G., Gupta, M. K., Singh, A., Nepali, K., Singh, H., Sharma, S. & Bedi, S. P. M., Jan 1 2019, In : MedChemComm. 10, 1, p. 128-147 20 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2018

(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo

Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., Apr 25 2018, In : European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Antitumour, acute toxicity and molecular modeling studies of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one against Ehrlich ascites carcinoma and sarcoma-180

Kumar, D., Sharma, P., Nepali, K., Mahajan, G., Mintoo, M. J., Singh, A., Singh, G., Mondhe, D. M., Singh, G., Jain, S. K., Gupta, G. K. & Ntie-Kang, F., Jun 1 2018, In : Heliyon. 4, 6, e00661.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition (Org. Biomol. Chem. (2016) 14 (716-723))

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., Jan 1 2018, In : Organic and Biomolecular Chemistry. 16, 25, p. 4734 1 p.

Research output: Contribution to journalArticle

2017

Benzoflavones as cholesterol esterase inhibitors: Synthesis, biological evaluation and docking studies

Singh, H., Singh, J. V., Gupta, M. K., Singh, P., Sharma, S., Nepali, K. & Bedi, P. M. S., Jan 1 2017, In : Bioorganic and Medicinal Chemistry Letters. 27, 4, p. 850-854 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Ring-opened tetrahydro-γ-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms

Nepali, K., Lee, H-Y., Lai, M-J., Ojha, R., Wu, T. Y., Wu, G. X., Chen, M-C. & Liou, J-P., Feb 15 2017, In : European Journal of Medicinal Chemistry. 127, p. 115-127 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Synthesis, screening and docking of fused pyrano[3,2-d]pyrimidine derivatives as xanthine oxidase inhibitor

Kaur, M., Kaur, A., Mankotia, S., Singh, H., Singh, A., Singh, J. V., Gupta, M. K., Sharma, S., Nepali, K. & Bedi, P. M. S., Jan 1 2017, In : European Journal of Medicinal Chemistry. 131, p. 14-28 15 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies

Singh, H., Singh, J. V., Gupta, M. K., Saxena, A. K., Sharma, S., Nepali, K. & Bedi, P. M. S., Jan 1 2017, In : Bioorganic and Medicinal Chemistry Letters. 27, 17, p. 3974-3979 6 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2016

Estimation of crotepoxide in the fruits of Piper attenuatum buch.-ham. using high-performance thin layer chromatography and high- performance liquid chromatography

Kumar, S., Gauttam, V., Bande, M. S. R., Nepali, K., Tyagi, A. & Dhar, K. L., Jan 1 2016, In : Current Pharmaceutical Analysis. 12, 4, p. 343-348 6 p.

Research output: Contribution to journalArticle

Naphthoflavones as antiproliferative agents: Design, synthesis and biological evaluation

Kumar, D., Singh, O., Nepali, K., Bedi, P. M. S., Qayum, A., Singh, S. & Jain, S. K., Jul 1 2016, In : Anti-Cancer Agents in Medicinal Chemistry. 16, 7, p. 881-890 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Triazole tethered C5-curcuminoid-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies

Singh, H., Kumar, M., Nepali, K., Gupta, M. K., Saxena, A. K., Sharma, S. & Bedi, P. M. S., Jun 30 2016, In : European Journal of Medicinal Chemistry. 116, p. 102-115 14 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2015

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., 2015, In : Organic and Biomolecular Chemistry. 14, 2, p. 716-723 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

4,6-diaryl pyrimidones as constrained chalcone analogues: Design, synthesis and evaluation as antiproliferative agents

Kumar, D., Nepali, K., Bedi, P. M. S., Kumar, S., Malik, F. & Jain, S., Jul 1 2015, In : Anti-Cancer Agents in Medicinal Chemistry. 15, 6, p. 793-803 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Anti-cancer pyrimidines in diverse scaffolds: A review of patent literature

Kaur, R., Kaur, P., Sharma, S., Singh, G., Mehndiratta, S., Bedi, P. M. S. & Nepali, K., Jan 1 2015, In : Recent Patents on Anti-Cancer Drug Discovery. 10, 1, p. 23-71 49 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Design, synthesis and evaluation of 2,4-diarylpyrano[3,2-c]chromen-5(4H)-one as a new class of non-purine xanthine oxidase inhibitors

Virdi, H. S., Sharma, S., Mehndiratta, S., Bedi, P. M. S. & Nepali, K., Sep 3 2015, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 30, 5, p. 730-736 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Screening of a library of 4-aryl/heteroaryl-4H-fused pyrans for xanthine oxidase inhibition: Synthesis, biological evaluation and docking studies

Kaur, R., Naaz, F., Sharma, S., Mehndiratta, S., Gupta, M. K., Bedi, P. M. S. & Nepali, K., Aug 23 2015, In : Medicinal Chemistry Research. 24, 8, p. 3334-3349 16 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2014

4,6-Diaryl/heteroarylpyrimidin-2(1H)-ones as a new class of xanthine oxidase inhibitors

Shukla, S., Kumar, D., Ojha, R., Gupta, M. K., Nepali, K. & Bedi, P. M. S., Jan 1 2014, In : Archiv der Pharmazie. 347, 7, p. 486-495 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Anti-asthmatic activity of azepino [2, 1-b] quinazolones, synthetic analogues of vasicine, an alkaloid from Adhatoda vasica

Rayees, S., Satti, N. K., Mehra, R., Nargotra, A., Rasool, S., Sharma, A., Sahu, P. K., Rajnikant, Gupta, V. K., Nepali, K. & Singh, G., Aug 5 2014, In : Medicinal Chemistry Research. 23, 9, p. 4269-4279 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Chalcone based azacarboline analogues as novel antitubulin agents: Design, synthesis, biological evaluation and molecular modelling studies

Sharma, S., Kaur, C., Budhiraja, A., Nepali, K., Gupta, M. K., Saxena, A. K. & Bedi, P. M. S., Oct 6 2014, In : European Journal of Medicinal Chemistry. 85, p. 648-660 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors

Sharma, S., Sharma, K., Ojha, R., Kumar, D., Singh, G., Nepali, K. & Bedi, P. M. S., Jan 15 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 2, p. 495-500 6 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Synthesis and cytotoxicity studies of 3,5-diaryl N-acetyl pyrazoline - Isatin hybrids

Sharma, M., Sharma, S., Buddhiraja, A., Saxena, A. K., Nepali, K. & Bedi, P. M. S., Oct 1 2014, In : Medicinal Chemistry Research. 23, 10, p. 4337-4344 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitors This Letter is dedicated to Dr. K. L. Dhar on the occasion of his 78th birthday.

Singh, H., Sharma, S., Ojha, R., Gupta, M. K., Nepali, K. & Bedi, P. M. S., Sep 1 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 17, p. 4192-4197 6 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2013

Aza analogs of flavones as potential antimicrobial agents

Sharma, S., Thakur, V., Ojha, R., Budhiraja, A., Nepali, K. & Singh Bedi, P. M., May 1 2013, In : Letters in Drug Design and Discovery. 10, 4, p. 327-334 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Bioactive metabolites from an endophytic fungus of Aspergillus species isolated from seeds of Gloriosa superba Linn.

Budhiraja, A., Nepali, K., Sapra, S., Gupta, S., Kumar, S. & Dhar, K. L., Jan 1 2013, In : Medicinal Chemistry Research. 22, 1, p. 323-329 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Design, synthesis and evaluation of arylidene pyrrolo and pyrido fused quinazolones as antimicrobial agents

Nepali, K., Ojha, R., Singh, A., Budhiraja, A., Bedi, P. M. S. & Dhar, K. L., Jul 1 2013, In : Letters in Drug Design and Discovery. 10, 6, p. 522-528 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Design and synthesis of aza-flavones as a new class of xanthine oxidase inhibitors

Dhiman, R., Sharma, S., Singh, G., Nepali, K. & Singh Bedi, P. M., Jan 1 2013, In : Archiv der Pharmazie. 346, 1, p. 7-16 10 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Isolation of New Cyclohexyl Epoxide from the Fruits of Piper attenuatum

Kumar, S., Mehndiratta, S., Nepali, K., Sapra, S., Koul, S. & Dhar, K. L., Jan 1 2013, In : Natural Products Journal. 3, 4, p. 249-251 3 p.

Research output: Contribution to journalArticle

Possible involvement of PPAR-γ in the anticonvulsant effect of aegle marmelos (L.) correa

Bhatti, R., Singh, J., Nepali, K. & Ishar, M. P. S., Aug 1 2013, In : Neurochemical Research. 38, 8, p. 1624-1631 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Quantitative determination of a novel pseudoalkaloid colchatetralene isolated from the mycoflora of Gloriosa superba Linn by HPTLC

Budhiraja, A., Nepali, K., Gouttam, V., Sapra, S. & Dhar, K. L., Jan 1 2013, In : Natural Products Journal. 3, 3, p. 176-181 6 p.

Research output: Contribution to journalArticle

Structure activity relationship of arylidene pyrrolo and pyrido [2,1-b] quinazolones as cytotoxic agents: Synthesis, SAR studies, biological evaluation and docking studies

Mangla, V., Nepali, K., Singh, G., Singh, J., Guru, S., Gupta, M. K., Mahajan, P., Saxena, A. K. & Dhar, K. L., Aug 1 2013, In : Medicinal Chemistry. 9, 5, p. 642-650 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Synthesis of 1,2,3-triazole tethered bifunctional hybrids by click chemistry and their cytotoxic studies

Singh, J., Sharma, S., Saxena, A. K., Nepali, K. & Bedi, P. M. S., Jul 1 2013, In : Medicinal Chemistry Research. 22, 7, p. 3160-3169 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2012

Antitussive effects of azepino[2,1-b]quinazolones

Nepali, K., Bande, M. S., Sapra, S., Garg, A., Kumar, S., Sharma, P., Goyal, R., Satti, N. K., Suri, O. P. & Dhar, K. L., Jul 1 2012, In : Medicinal Chemistry Research. 21, 7, p. 1271-1277 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Effect of nitrogen insertion on the antitussive properties of menthol and camphor

Kumar, N., Nepali, K., Sapra, S., Bijjem, K. R. V., Kumar, R., Suri, O. P. & Dhar, K. L., Apr 1 2012, In : Medicinal Chemistry Research. 21, 4, p. 531-537 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Effect of ring A and ring B substitution on the cytotoxic potential of pyrazole tethered chalcones

Nepali, K., Kadian, K., Ojha, R., Dhiman, R., Garg, A., Singh, G., Buddhiraja, A., Bedi, P. M. S. & Dhar, K. L., Oct 1 2012, In : Medicinal Chemistry Research. 21, 10, p. 2990-2997 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Evaluation of antiasthmatic activity of 7,8,9, 10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one in combination with ambroxol in Guinea pigs

Bande, M., Nepali, K., Goyal, R., Thakur, V., Suri, J., Budhiraja, R. D., Suri, O. P., Singh Bedi, P. M. & Dhar, K. L., Dec 1 2012, In : Medicinal Chemistry Research. 21, 12, p. 4158-4167 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes

Malhi, S. S., Budhiraja, A., Arora, S., Chaudhari, K. R., Nepali, K., Kumar, R., Sohi, H. & Murthy, R. S. R., Aug 1 2012, In : International Journal of Pharmaceutics. 432, 1-2, p. 63-74 12 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Synthesis, in vitro hydrolysis, bioanalytical method development and pharmacokinetic study of an amide Prodrug of Ibuprofen

Ojha, R., Nepali, K., Goyal, R., Dhar, K. L. & Bhardwaj, T., Jul 23 2012, In : Current Pharmaceutical Analysis. 8, 3, p. 261-271 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis and biological evaluation of naphthalene, furan and pyrrole based chalcones as cytotoxic and antimicrobial agents

Budhiraja, A., Kadian, K., Kaur, M., Aggarwal, V., Garg, A., Sapra, S., Nepali, K., Suri, O. P. & Dhar, K. L., Sep 1 2012, In : Medicinal Chemistry Research. 21, 9, p. 2133-2140 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2011

A rational approach for the design and synthesis of 1-acetyl-3,5-diaryl-4, 5-dihydro(1H)pyrazoles as a new class of potential non-purine xanthine oxidase inhibitors

Nepali, K., Singh, G., Turan, A., Agarwal, A., Sapra, S., Kumar, R., Banerjee, U. C., Verma, P. K., Satti, N. K., Gupta, M. K., Suri, O. P. & Dhar, K. L., Mar 15 2011, In : Bioorganic and Medicinal Chemistry. 19, 6, p. 1950-1958 9 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

N-(1,3-Diaryl-3-oxopropyl)amides as a new template for xanthine oxidase inhibitors

Nepali, K., Agarwal, A., Sapra, S., Mittal, V., Kumar, R., Banerjee, U. C., Gupta, M. K., Satti, N. K., Suri, O. P. & Dhar, K. L., Sep 15 2011, In : Bioorganic and Medicinal Chemistry. 19, 18, p. 5569-5576 8 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
2010

Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents

Sandhu, H. S., Sapra, S., Gupta, M., Nepali, K., Gautam, R., Yadav, S., Kumar, R., Jachak, S. M., Chugh, M., Gupta, M. K., Suri, O. P. & Dhar, K. L., Aug 1 2010, In : Bioorganic and Medicinal Chemistry. 18, 15, p. 5626-5633 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Synthesis and biological evaluation of chalcones having heterosubstituent(s)

Sweety, Kumar, S., Nepali, K., Sapra, S., Suri, O. P., Dhar, K. L., Sarma, G. S. & Saxena, A. K., Nov 1 2010, In : Indian Journal of Pharmaceutical Sciences. 72, 6, p. 801-806 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2008

Formulation and evaluation of diclofenac sodium gel by using natural polymer

Ahuja, N., Saini, V., Bishnoi, V. K., Garg, A., Hisoria, M., Sharma, J. & Nepali, K., Jan 1 2008, In : Rasayan Journal of Chemistry. 1, 3, p. 564-566 3 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Formulation and evaluation of lansoprazole niosome

Ahuja, N., Saini, V., Bishnoi, V. K., Garg, A., Hisoria, M., Sharma, J. & Nepali, K., Jan 1 2008, In : Rasayan Journal of Chemistry. 1, 3, p. 561-563 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)