Projects per year
Personal profile
Education
- 2009 Ph.D. Institute of Basic Medical Sciences, National Cheng Kung University
- 2004 MS. Institute of Biomedical Sciences, National Sun Yat-sen University
- 2002 B.S. Department of Marine Biotechnology and Resources, National Sun Yat-sen University
Experience
- 2018- Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018- Director, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2017- Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2016- Associate Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2012 Assistant Research Fellow, Institute for Cancer Biology and Drug Discovery, Taipei Medical University
- 2010-2012 Postdoctoral Fellow in Division of Medicinal Chemistry, Ohio State University, USA
Awards
- 2009 National Cheng Kung University College of Medicine-Award of Excellent Paper
Research Interests
- Signal transduction of tumor biology
- Drug repurposing of cancer
- The roles of miRNAs in cancer
URL
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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長鏈非編碼RNA-CRNDE調控代謝重整與細胞自噬之機制探討
3/1/21 → 2/28/22
Project: C - Project of Alliance › o - Chi Mei Medical Center
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探討TM4SF1-DDR1 couple在的大腸直腸癌細胞中的內生性與後天性Oxaliplatin resistance的分子機轉研究
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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探討TM4SF1-DDR1 couple在的大腸直腸癌細胞中的內生性與後天性Oxaliplatin resistance的分子機轉研究
1/1/20 → 12/31/20
Project: A - Government Institution › d - Ministry of Education
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Investigation the Functional Roles and Molecular Mechanism of Long Non-Coding Rna-Crnde in Autophagy and Oxaliplatin Drug Resistance
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
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長鏈非編碼核糖核酸LncHIFCAR/MIR31HG調控的中心網絡在胰臟癌的轉譯研究-探討XPO-5/Pin1 調控胰臟癌相關之抑癌微核醣核酸之表現：參與在MIR31HG 的訊息調控途徑
1/1/19 → 12/1/19
Project: A - Government Institution › d - Ministry of Education
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Gene signatures and prognostic analyses of the tob/btg pituitary tumor-transforming gene (PTTG) family in clinical breast cancer patients
Wu, C. C., Ekanem, T. I., Phan, N. N., Loan, D. T. T., Hou, S. Y., Lee, K. H. & Wang, C. Y., 2020, In: International Journal of Medical Sciences. 17, 18, p. 3112-3124 13 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer
Ekanem, T. I., Tsai, W. L., Lin, Y. H., Tan, W. Q., Chang, H. Y., Huang, T. C., Chen, H. Y. & Lee, K. H., Aug 22 2020, In: Molecules. 25, 17, 3826.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Purα regulates the induction of Znf179 transcription during neuronal differentiation
Kuo, C. J., Lee, K. H., Huang, C. C., Wang, I. F., Hsieh, C. C. J., Lin, H. C. & Lee, Y. C., 2020, (Accepted/In press) In: Biochemical and Biophysical Research Communications. 533, 4, p. 1477-1483 7 p.Research output: Contribution to journal › Article › peer-review
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Dietary flavonoids luteolin and quercetin inhibit migration and invasion of squamous carcinoma through reduction of src/stat3/s100a7 signaling
Fan, J. J., Hsu, W. H., Lee, K. H., Chen, K. C., Lin, C. W., Lee, Y. L. A., Ko, T. P., Lee, L. T., Lee, M. T., Chang, M. S. & Cheng, C. H., Nov 2019, In: Antioxidants. 8, 11, 557.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (Scopus) -
E2f1 regulates the induction of promyelocytic leukemia zinc finger transcription in neuronal differentiation of pluripotent P19 embryonal carcinoma cells
Lin, H. C., Ko, C. Y., Lee, K. H., Chen, I. H., Kao, T. J., Chang, W. C., Hsu, T. I. & Lee, Y. C., May 7 2019, In: Biochemical and Biophysical Research Communications. 512, 3, p. 629-634 6 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus)
Datasets
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Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y. (Contributor), Huang, W. (Contributor), Lin, J. (Contributor), Kao, T. (Contributor), Lin, H. (Contributor), Lee, K. (Contributor), Lin, H. (Contributor), Shen, C. (Contributor), Chang, W. (Contributor) & Huang, C. (Contributor), Unknown Publisher, Nov 8 2018
DOI: 10.6084/m9.figshare.c.4294289.v1, https://figshare.com/collections/Znf179_E3_ligase-mediated_TDP-43_polyubiquitination_is_involved_in_TDP-43-_ubiquitinated_inclusions_UBI_-related_neurodegenerative_pathology/4294289/1
Dataset
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Additional file 3: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y. (Contributor), Huang, W. (Contributor), Lin, J. (Contributor), Kao, T. (Contributor), Lin, H. (Contributor), Lee, K. (Contributor), Lin, H. (Contributor), Shen, C. (Contributor), Chang, W. (Contributor) & Huang, C. (Contributor), Unknown Publisher, Nov 8 2018
DOI: 10.6084/m9.figshare.7313816.v1, https://springernature.figshare.com/articles/Additional_file_3_of_Znf179_E3_ligase-mediated_TDP-43_polyubiquitination_is_involved_in_TDP-43-_ubiquitinated_inclusions_UBI_-related_neurodegenerative_pathology/7313816/1
Dataset
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Additional file 2: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y. (Contributor), Huang, W. (Contributor), Lin, J. (Contributor), Kao, T. (Contributor), Lin, H. (Contributor), Lee, K. (Contributor), Lin, H. (Contributor), Shen, C. (Contributor), Chang, W. (Contributor) & Huang, C. (Contributor), Unknown Publisher, Nov 8 2018
DOI: 10.6084/m9.figshare.7313798.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Znf179_E3_ligase-mediated_TDP-43_polyubiquitination_is_involved_in_TDP-43-_ubiquitinated_inclusions_UBI_-related_neurodegenerative_pathology/7313798/1
Dataset
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Additional file 1: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y. (Contributor), Huang, W. (Contributor), Lin, J. (Contributor), Kao, T. (Contributor), Lin, H. (Contributor), Lee, K. (Contributor), Lin, H. (Contributor), Shen, C. (Contributor), Chang, W. (Contributor) & Huang, C. (Contributor), Unknown Publisher, Nov 8 2018
DOI: 10.6084/m9.figshare.7313777.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Znf179_E3_ligase-mediated_TDP-43_polyubiquitination_is_involved_in_TDP-43-_ubiquitinated_inclusions_UBI_-related_neurodegenerative_pathology/7313777/1
Dataset