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Personal profile

Research Interests

  • Medical biochemistry and molecular biology
  • cellular signaling transduction
  • Epigenetic regulation
  • microRNA regulation
  • glioma tumorigenesis

Education

  • 2005 PhD Institute of Biomedical Sciences, National Sun Yat-sen University, Taiwan
  • 1999 M.S Department of Biochemistry, Kaohsiung Medical University, Taiwan
  • 1995 B.S. Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taiwan

Experience

  • 2012 Assistant Professor, Department of Biochemistry and molecular cell biology, School of Medicine, Taipei Medical University,Taiwan
  • 2009 Postdoctoral Fellow, School of Medicine, Kaohsiung Medical University, Taiwan

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Projects 2013 2019

探討受甲基化調控 MicroRNA-4792參與 Temozolomide腦瘤抗藥性形成之分子機轉

Chen, K.

3/1/172/28/18

Project: C - Project of Alliancep - Cathay General Hospital

Investigation of Dna Methylation-Influenced Microrna-Gene Networks in Temozolomide-Induced Glioma Cell Death and Chemoresistance

Chen, K.

8/1/167/31/17

Project: A - Government Institutionb - Ministry of Science and Technology

Investigation of Nuclear microRNA Signatures and Their Functional Effects on Glioblastoma Multiforme Pathology

Chen, K. & Shih, C.

8/1/157/31/16

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 1999 2018

  • 1288 Citations
  • 20 h-Index
  • 69 Article
  • 1 Comment/debate
3 Citations (Scopus)

Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells

Chen, P. C., Lee, W. Y., Ling, H. H., Cheng, C. H., Chen, K. C. & Lin, C. W., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Fibroblasts
Nicotine
Chemical activation
Cells
4 Citations (Scopus)

Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction

Chen, K. C., Hsu, W. H., Ho, J. Y., Lin, C. W., Chu, C. Y., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., Jan 1 2018, (Accepted/In press) In : Journal of Food and Drug Analysis.

Research output: Contribution to journalArticle

Luteolin
luteolin
Quercetin
Flavonoids
metastasis
1 Citation (Scopus)

Gene landscape and correlation between B-cell infiltration and programmed death ligand 1 expression in lung adenocarcinoma patients from The Cancer Genome Atlas data set

Ho, K-H., Chang, C-J., Huang, T-W., Shih, C-M., Liu, A-J., Chen, P-H., Cheng, K-T. & Chen, K-C., Dec 1 2018, In : PLoS One. 13, 12, p. e0208459 e0208459.

Research output: Contribution to journalArticle

2 Citations (Scopus)

microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells

Chen, P. H., Liu, A. J., Ho, K. H., Chiu, Y. T., Anne Lin, Z. H., Lee, Y. T., Shih, C. M. & Chen, K. C., Aug 1 2018, In : Chemico-Biological Interactions. 291, p. 144-151 8 p.

Research output: Contribution to journalArticle

Autophagy
Myeloid Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
MicroRNAs
Pharmaceutical Preparations
1 Citation (Scopus)

miR-4725-3p targeting stromal interacting molecule 1 signaling is involved in xanthohumol inhibition of glioma cell invasion

Ho, K. H., Chang, C. K., Chen, P. H., Wang, Y. J., Chang, W. C. & Chen, K. C., Aug 1 2018, In : Journal of Neurochemistry. 146, 3, p. 269-288 20 p.

Research output: Contribution to journalArticle

Glioma
Molecules
Glioblastoma
Humulus
Tumors