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Personal profile

Research Interests

  • Medical biochemistry and molecular biology
  • cellular signaling transduction
  • Epigenetic regulation
  • microRNA regulation
  • glioma tumorigenesis

Education

  • 2005-2009 PhD Institute of Biomedical Sciences, National Sun Yat-sen University, Taiwan
  • 1998-2000 M.S Department of Biochemistry, Kaohsiung Medical University, Taiwan
  • 1994-1995 B.S. Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taiwan

Experience

  • Associate Professor, Department of Biochemistry and molecular cell biology, School of Medicine, Taipei Medical University,Taiwan
  • 2012.10-2017.07 Assistant Professor, Department of Biochemistry and molecular cell biology, School of Medicine, Taipei Medical University,Taiwan
  • 2012.08-2012.09 Assistant Researcher, Department of Biochemistry and molecular cell biology, School of Medicine, Taipei Medical University,Taiwan
  • 2009.10-2012.08 Postdoctoral Fellow, School of Medicine, Kaohsiung Medical University, Taiwan

Fingerprint Dive into the research topics where Ku-Chung Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
MicroRNAs Medicine & Life Sciences
Elapidae Medicine & Life Sciences
Glioma Medicine & Life Sciences
Neuroblastoma Medicine & Life Sciences
p38 Mitogen-Activated Protein Kinases Medicine & Life Sciences
Phospholipases A2 Chemical Compounds
Chemical activation Chemical Compounds
Cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2019

探討受甲基化調控 MicroRNA-4792參與 Temozolomide腦瘤抗藥性形成之分子機轉

Chen, K.

3/1/172/28/18

Project: C - Project of Alliancep - Cathay General Hospital

Investigation of Dna Methylation-Influenced Microrna-Gene Networks in Temozolomide-Induced Glioma Cell Death and Chemoresistance

Chen, K.

8/1/167/31/17

Project: A - Government Institutionb - Ministry of Science and Technology

Investigation of Nuclear microRNA Signatures and Their Functional Effects on Glioblastoma Multiforme Pathology

Chen, K. & Shih, C.

8/1/157/31/16

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 1999 2019

  • 1324 Citations
  • 20 h-Index
  • 69 Article
  • 1 Comment/debate

Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells

Wong, J. H., Wang, Y. S., Nam, S., Ho, K. H., Chang, C. M., Chen, K. C., Chen, Y. F. & Chang, W. C., Jan 1 2019, In : Environmental Toxicology.

Research output: Contribution to journalArticle

Plasticizers
phthalate
Cyclooxygenase 2
Stomach
Adenocarcinoma

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

Wong, J. Y. Y., Zhang, H., Hsiung, C. A., Shiraishi, K., Yu, K., Matsuo, K., Wong, M. P., Hong, Y. C., Wang, J., Seow, W. J., Wang, Z., Song, M., Kim, H. N., Chang, I. S., Chatterjee, N., Hu, W., Wu, C., Mitsudomi, T., Zheng, W., Kim, J. H. & 166 others, Seow, A., Caporaso, N. E., Shin, M. H., Chung, L. P., An, S. J., Wang, P., Yang, Y., Zheng, H., Yatabe, Y., Zhang, X. C., Kim, Y. T., Cai, Q., Yin, Z., Kim, Y. C., Bassig, B. A., Chang, J., Ho, J., Ji, B. T., Daigo, Y., Ito, H., Momozawa, Y., Ashikawa, K., Kamatani, Y., Honda, T., Hosgood, H. D., Sakamoto, H., Kunitoh, H., Tsuta, K., Watanabe, S. I., Kubo, M., Miyagi, Y., Nakayama, H., Matsumoto, S., Tsuboi, M., Goto, K., Shi, J., Song, L., Hua, X., Takahashi, A., Goto, A., Minamiya, Y., Shimizu, K., Tanaka, K., Wei, F., Matsuda, F., Su, J., Kim, Y. H., Oh, I. J., Song, F., Su, W. C., Chen, Y. M., Chang, G. C., Chen, K. Y., Huang, M. S., Chien, L. H., Xiang, Y. B., Park, J. Y., Kweon, S. S., Chen, C. J., Lee, K. M., Blechter, B., Li, H., Gao, Y. T., Qian, B., Lu, D., Liu, J., Jeon, H. S., Hsiao, C. F., Sung, J. S., Tsai, Y. H., Jung, Y. J., Guo, H., Hu, Z., Wang, W. C., Chung, C. C., Burdett, L., Yeager, M., Hutchinson, A., Berndt, S. I., Wu, W., Pang, H., Li, Y., Choi, J. E., Park, K. H., Sung, S. W., Liu, L., Kang, C. H., Zhu, M., Chen, C. H., Yang, T. Y., Xu, J., Guan, P., Tan, W., Wang, C. L., Hsin, M., Sit, K. Y., Ho, J., Chen, Y., Choi, Y. Y., Hung, J. Y., Kim, J. S., Yoon, H. I., Lin, C. C., Park, I. K., Xu, P., Wang, Y., He, Q., Perng, R. P., Chen, C. Y., Vermeulen, R., Wu, J., Lim, W. Y., Chen, K. C., Li, Y. J., Li, J., Chen, H., Yu, C. J., Jin, L., Chen, T. Y., Jiang, S. S., Liu, J., Yamaji, T., Hicks, B., Wyatt, K., Li, S. A., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Li, X., Ren, Y., Cui, P., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Yang, K., Jiang, G., Fei, K., Wu, G., Lin, H. C., Chen, H. L., Fang, Y. H., Tsai, F. Y., Hsieh, W. S., Yu, J., Stevens, V. L., Laird-Offringa, I. A., Marconett, C. N., Rieswijk, L., Chao, A., Yang, P. C., Shu, X. O., Wu, T., Wu, Y. L., Lin, D., Chen, K., Zhou, B., Huang, Y. C., Kohno, T., Shen, H., Chanock, S. J., Rothman, N. & Lan, Q., Jan 1 2019, In : Genomics.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Genome-Wide Association Study
Tuberculosis
Smoking
Infection
4 Citations (Scopus)

Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells

Chen, P. C., Lee, W. Y., Ling, H. H., Cheng, C. H., Chen, K. C. & Lin, C. W., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Fibroblasts
Nicotine
Chemical activation
Cells
6 Citations (Scopus)

Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction

Chen, K. C., Hsu, W. H., Ho, J. Y., Lin, C. W., Chu, C. Y., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., Jan 1 2018, (Accepted/In press) In : Journal of Food and Drug Analysis.

Research output: Contribution to journalArticle

Luteolin
luteolin
Quercetin
Flavonoids
metastasis
1 Citation (Scopus)

Gene landscape and correlation between B-cell infiltration and programmed death ligand 1 expression in lung adenocarcinoma patients from The Cancer Genome Atlas data set

Ho, K-H., Chang, C-J., Huang, T-W., Shih, C-M., Liu, A-J., Chen, P-H., Cheng, K-T. & Chen, K-C., Dec 1 2018, In : PLoS One. 13, 12, p. e0208459 e0208459.

Research output: Contribution to journalArticle