Projects per year
Personal profile
Education
- 2001-2005 Ph.D., Biological Sciences-Genetics & Complex Diseases, Graduate School of Arts & Sciences, Harvard University
- 1986-1993 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
Postdoctoral Training
- 2005-2007 Postdoctoral Fellow, Institute for Medicine and Engineering, University of Pennsylvania, PA, USA
- 2005-2007 Postdoctoral Fellow, Department of Surgery and Center for Bioengineering & Tissue Regeneration, University of California, San Francisco, CA, USA
- 1998-2000 Clinical Fellow, Division of Critical Care, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
- 1996-1998 Chief Resident, Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
- 1993-1996 Resident, Department of Medicine, Taipei Veterans General Hospital, Taiwan
Academic Appointments
- 2021.01- Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2017- Joint Associate Investigator, National Institute of Cancer Research, National Health Research Institutes, Taiwan
- 2014.08- Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2014- Associate Professor of Medicine, Graduate Institute of Clinical Research, School of Medicine, TMU
- 2014-2017 Associate Investigator, National Institute of Cancer Research, National Health Research Institutes
- 2008-2013 Assistant Investigator, National Institute of Cancer Research, National Health Research Institutes
- Clinical Appointments
- 2008.08-2014.07 Assistant Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2007.09-2008.07 Assistant Professor, Department of Internal Medicine, School of Medicine, Taipei Medical University
Clinical Appointments
- 2019- Director, Clinical Research Center, Wan Fang Hospital, Taipei Medical University
- 2019- Deputy Director, Integrative Therapy Center for Gastroenterological Cancers, Wan Fan Hospital, Taipei Medical University
- 2018- Attending Physician, Division of Gastroenterology, Department of Medicine, Wan Fang Hospital, Taipei Medical University
- 2008.08-2017.01 Attending Physician, National Institute of Cancer Research, National Health Research Institutes
- 2009-2017 Attending Physician, Division of Hematology-oncology, Department of Medicine, National Cheng-Kung University Hospital, Tainan, Taiwan
- 2000.10-2004.09 Attending Physician, Department of Medicine, Taipei Veterans General Hospital
- 1993.09-2000.09 Resident Physician, Department of Medicine, Taipei Veterans General Hospital
Awards
- 2019 Research Dissertation Award - Clinical Research Award, Taipei Medical University
- 2018 Outstanding Research Award (Life Science), Ministry of Science and Technology (MOST), Taiwan
- 2018 The 5th Kobayashi's Foundation Award, Kobayashi Foundation for Cancer Research, Japan
- 2017 Ta-Cheng Tung's Basic Cancer Research Award, Taiwan Oncology Society
- 2017 The Breast Journal Award, Wiley-Blackwell, USA
- 2016 Research Prize, NCKUH, Taiwan
- 2014 Young Scientist Research Achievement Award, National Health Research Institutes, Taiwan
- 2014 Research Prize, NCKUH, Taiwan
- 2012 Merit Award, Asian Clinical Oncology Society (ACOS)
- 2005 Ruth L. Kirschstein National Research Service Award, National Institutes of Health (NIH), USA
- 2004 Harvard Presidential Scholar, Harvard University, Cambridge, MA, USA
- 2004 Glenn/AFAR Scholar, American Federation for Aging Research, USA
- 2001-2003 Government Scholar, Ministry of Education (MOE), Taiwan
- 2001 Scholarship of the Ivy Association for Cultural and Educational Exchange, Taiwan
- 1999 Research Prize, TVGH, Taiwan
Research Interests
- Cell and Molecular Biology
- Cancer Biology
- Cancer Stem Cells
- Cancer Molecular Medicine
- Pancreatic Cancer
- Breast Cancer
- Cancer Treatment Resistance
Other
Medical Licensure
- 2011 ECFMG Certificate, USA
- 1999 Board Certified, Gastroenterology, Taiwan
- 1999 Board Certified, Digestive Endoscopy, Taiwan
- 1996 Board Certified, Internal Medicine, Taiwan
Memberships
- 2015- Taiwan Oncology Society
- 2013- American Association for Cancer Research
- 2006- The American Society for Cell Biology
- 2006- Harvard Alumni Association
- 1999- The Digestive Endoscopy Society of Taiwan
- 1999- The Gastroenterology Society of Taiwan
- 1996- Taiwan Society of Internal Medicine
Fingerprint
- 6 Similar Profiles
Network
Projects
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進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(2/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功 能篩選:聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(1/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
-
ASPM-PAR-PCP訊息軸於侵犯性癌幹細胞造成癌轉移的角色與其標靶治療(2/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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2-1-3 精進核心研究服務平台-胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發
1/1/20 → 12/1/20
Project: B - Project of TMU › h - Higher Education Sprout Project
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進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(1/3)相對補助
8/1/19 → 7/31/20
Project: A - Government Institution › f - Other (Funded by Government)
Research output
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A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study
Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., Jan 2020, In: European Journal of Cancer. 124, p. 123-130 8 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma
Liao, W. Y., Hsu, C. C., Chan, T. S., Yen, C. J., Chen, W. Y., Pan, H. W. & Tsai, K. K., Mar 10 2020, In: Stem Cell Reports. 14, 3, p. 462-477 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling
Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W-Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., Feb 21 2019, In: Oncogene. 38, 8, p. 1340-1353 14 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Correction: ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling (Oncogene, (2019), 38, 8, (1340-1353), 10.1038/s41388-018-0497-4)
Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W-Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., Feb 21 2019, In: Oncogene. 38, 8, p. 1354 1 p.Research output: Contribution to journal › Comment/debate › peer-review
4 Citations (Scopus) -
Histone demethylase KDM4C stimulates the proliferation of prostate cancer cells via activation of AKT and c-Myc
Lin, C. Y., Wang, B. J., Chen, B. C., Tseng, J. C., Jiang, S. S., Tsai, K. K., Shen, Y. Y., Yuh, C. H., Sie, Z. L., Wang, W. C., Kung, H. J. & Chuu, C. P., Nov 13 2019, In: Cancers. 11, 11, 1785.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus)