Kelvin Kun-Chih Tsai

https://orcid.org/0000-0002-1612-2868

Emailtsaik@tmu.edu.tw

Source: Scopus
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Personal profile

Education

2001-2005 Ph.D., Biological Sciences-Genetics & Complex Diseases, Graduate School of Arts & Sciences, Harvard University
1986-1993 M.D., School of Medicine, College of Medicine, Taipei Medical University

Experience

Postdoctoral Training

2005-2007 Postdoctoral Fellow, Institute for Medicine and Engineering, University of Pennsylvania, PA, USA
2005-2007 Postdoctoral Fellow, Department of Surgery and Center for Bioengineering & Tissue Regeneration, University of California, San Francisco, CA, USA
1998-2000 Clinical Fellow, Division of Critical Care, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
1996-1998 Chief Resident, Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
1993-1996 Resident, Department of Medicine, Taipei Veterans General Hospital, Taiwan

Academic Appointments

2021.01- Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
2017- Joint Associate Investigator, National Institute of Cancer Research, National Health Research Institutes, Taiwan
2014.08- Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
2014- Associate Professor of Medicine, Graduate Institute of Clinical Research, School of Medicine, TMU
2014-2017 Associate Investigator, National Institute of Cancer Research, National Health Research Institutes
2008-2013 Assistant Investigator, National Institute of Cancer Research, National Health Research Institutes
Clinical Appointments
2008.08-2014.07 Assistant Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
2007.09-2008.07 Assistant Professor, Department of Internal Medicine, School of Medicine, Taipei Medical University

Clinical Appointments

2019- Director, Clinical Research Center, Wan Fang Hospital, Taipei Medical University
2019- Deputy Director, Integrative Therapy Center for Gastroenterological Cancers, Wan Fan Hospital, Taipei Medical University
2018- Attending Physician, Division of Gastroenterology, Department of Medicine, Wan Fang Hospital, Taipei Medical University
2008.08-2017.01 Attending Physician, National Institute of Cancer Research, National Health Research Institutes
2009-2017 Attending Physician, Division of Hematology-oncology, Department of Medicine, National Cheng-Kung University Hospital, Tainan, Taiwan
2000.10-2004.09 Attending Physician, Department of Medicine, Taipei Veterans General Hospital
1993.09-2000.09 Resident Physician, Department of Medicine, Taipei Veterans General Hospital

Awards

2019 Research Dissertation Award - Clinical Research Award, Taipei Medical University
2018 Outstanding Research Award (Life Science), Ministry of Science and Technology (MOST), Taiwan
2018 The 5th Kobayashi's Foundation Award, Kobayashi Foundation for Cancer Research, Japan
2017 Ta-Cheng Tung's Basic Cancer Research Award, Taiwan Oncology Society
2017 The Breast Journal Award, Wiley-Blackwell, USA
2016 Research Prize, NCKUH, Taiwan
2014 Young Scientist Research Achievement Award, National Health Research Institutes, Taiwan
2014 Research Prize, NCKUH, Taiwan
2012 Merit Award, Asian Clinical Oncology Society (ACOS)
2005 Ruth L. Kirschstein National Research Service Award, National Institutes of Health (NIH), USA
2004 Harvard Presidential Scholar, Harvard University, Cambridge, MA, USA
2004 Glenn/AFAR Scholar, American Federation for Aging Research, USA
2001-2003 Government Scholar, Ministry of Education (MOE), Taiwan
2001 Scholarship of the Ivy Association for Cultural and Educational Exchange, Taiwan
1999 Research Prize, TVGH, Taiwan

Research Interests

Cell and Molecular Biology
Cancer Biology
Cancer Stem Cells
Cancer Molecular Medicine
Pancreatic Cancer
Breast Cancer
Cancer Treatment Resistance

Other

Medical Licensure

2011 ECFMG Certificate, USA
1999 Board Certified, Gastroenterology, Taiwan
1999 Board Certified, Digestive Endoscopy, Taiwan
1996 Board Certified, Internal Medicine, Taiwan

Memberships

2015- Taiwan Oncology Society
2013- American Association for Cancer Research
2006- The American Society for Cell Biology
2006- Harvard Alumni Association
1999- The Digestive Endoscopy Society of Taiwan
1999- The Gastroenterology Society of Taiwan
1996- Taiwan Society of Internal Medicine

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3 Active
14 Finished

進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(2/3)
Tsai, K. K.
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(1/3)
Tsai, K. K.
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
ASPM-PAR-PCP訊息軸於侵犯性癌幹細胞造成癌轉移的角色與其標靶治療(2/3)
Tsai, K. K.
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
2-1-3 精進核心研究服務平台-胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發
Tsai, K. K.
1/1/20 → 12/1/20
Project: B - Project of TMU › h - Higher Education Sprout Project
進展性胰臟癌新穎增進免疫療法的治療策略與生物指標－節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(1/3)相對補助
Tsai, K. K.
8/1/19 → 7/31/20
Project: A - Government Institution › f - Other (Funded by Government)

1792 Citations
23 h-Index
34 Article
4 Review article
2 Comment/debate

A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study
Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., Jan 2020, In: European Journal of Cancer. 124, p. 123-130 8 p.
Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus)
Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma
Liao, W. Y., Hsu, C. C., Chan, T. S., Yen, C. J., Chen, W. Y., Pan, H. W. & Tsai, K. K., Mar 10 2020, In: Stem Cell Reports. 14, 3, p. 462-477 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Citations (Scopus)
ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling
Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W-Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., Feb 21 2019, In: Oncogene. 38, 8, p. 1340-1353 14 p.
Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus)
Correction: ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling (Oncogene, (2019), 38, 8, (1340-1353), 10.1038/s41388-018-0497-4)
Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W-Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., Feb 21 2019, In: Oncogene. 38, 8, p. 1354 1 p.
Research output: Contribution to journal › Comment/debate › peer-review
4 Citations (Scopus)
Histone demethylase KDM4C stimulates the proliferation of prostate cancer cells via activation of AKT and c-Myc
Lin, C. Y., Wang, B. J., Chen, B. C., Tseng, J. C., Jiang, S. S., Tsai, K. K., Shen, Y. Y., Yuh, C. H., Sie, Z. L., Wang, W. C., Kung, H. J. & Chuu, C. P., Nov 13 2019, In: Cancers. 11, 11, 1785.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Citations (Scopus)