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Projects 2016 2019

研發與設計蛋白質激?抑制劑應用於癌症之治療

Hsu, K.

8/1/187/31/19

Project: A - Government Institutionb - Ministry of Science and Technology

針對致癌蛋白質激?開發新穎選擇性抑制劑

Hsu, K.

8/1/177/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Discovery of multitarget inhibitors for colorectal cancer treatment using Pharmalogs

Hsu, K. & Cheng, Y.

2/1/161/31/17

Project: A - Government Institutionb - Ministry of Science and Technology

新聘教師研究補助

Hsu, K.

1/1/1612/31/16

Project: B - Project of TMUh - Other (Funded by TMU)

Research Output 2008 2019

  • 423 Citations
  • 11 h-Index
  • 40 Article
  • 3 Conference contribution
  • 2 Review article
1 Citation (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
3 Citations (Scopus)

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes

Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Jan 29 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

tau Proteins
Histone Deacetylase Inhibitors
Alzheimer Disease
Hydroxamic Acids
Phenotype
3 Citations (Scopus)

A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo

Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 205.

Research output: Contribution to journalArticle

Tubulin Modulators
Histone Deacetylases
Neoplasms
Tubulin
Molecular Docking Simulation

A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions

Lin, T. E., HuangFu, W-C., Chao, M-W., Sung, T-Y., Chang, C-D., Chen, Y-Y., Hsieh, J-H., Tu, H-J., Huang, H-L., Pan, S-L. & Hsu, K-C., 2018, In : Frontiers in Pharmacology. 9, p. 1379

Research output: Contribution to journalArticle

Janus Kinases
Phosphotransferases
Binding Sites
Pharmacology
Cytokine Receptors

Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation

Chen, L. C., Tseng, H. J., Liu, C. Y., Huang, Y. Y., Yen, C. C., Weng, J. R., Lu, Y. L., Hou, W. C., Lin, T. E., Pan, I. H., Huang, K. K., Huang, W. J. & Hsu, K. C., Jul 3 2018, In : Frontiers in Pharmacology. 9, JUL, 708.

Research output: Contribution to journalArticle

Diarylheptanoids
Histone Deacetylases
Amyloid
Alzheimer Disease
Pyrogallol