Projects per year
Personal profile
Education
- 2011 國立交通大學生物資訊及系統生物研究所博士
- 2007 國立交通大學生物資訊研究所碩士
- 2005 國立交通大學生物科技學系學士
Experience
- 2019- 臺北醫學大學癌症生物學與藥物研發研究所副教授
- 2019- 臺北醫學大學生技醫療產業研發博士學位學程副教授
- 2018- 臺北醫學大學癌症生物學與藥物研發研究所助理教授
- 2015- 臺北醫學大學癌症生物學與藥物研發博士學位學程助理教授
- 2013-2015 國立交通大學約聘助理研究員
- 2011-2013 國立交通大學博士後研究員
Research Interests
- 生物學之生化及分子生物
- 生物資訊與醫療資訊
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Projects
電腦輔助設計與研發新穎DYRK1B抑制劑
1/1/20 → 12/31/20
Project: A - Government Institution › d - Ministry of Education
Design and Potency Optimization of Kinase Inhibitors for Cancer Treatment(1/3)
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
Integrated Bioinformatics Approaches to Study the Mechanisms and Discover Drugs of Hcv-Induced Type 2 Diabetes Mellitus(3/3)
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
Discovery and Design of Kinase Inhibitors for Cancer Treatment
8/1/18 → 7/1/19
Project: A - Government Institution › b - Ministry of Science and Technology
Discovery of Selective Inhibitors for Oncoprotein Kinases
8/1/17 → 7/31/18
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors
Hsu, K. C., HuangFu, W. C., Lin, T. E., Chao, M. W., Sung, T. Y., Chen, Y. Y., Pan, S. L., Lee, J. C., Tzou, S. C., Sun, C. M. & Yang, J. M., Dec 1 2020, In : Scientific Reports. 10, 1, 10510.Research output: Contribution to journal › Article
Open Access
Corrigendum to“Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo”[Eur. J. Med. Chem. 190 (2020 Mar 15) 112086] (European Journal of Medicinal Chemistry (2020) 190, (S0223523420300532), (10.1016/j.ejmech.2020.112086))
Ojha, R., Nepali, K., Chen, C. H., Chuang, K. H., Wu, T. Y., Lin, T. E., Hsu, K. C., Chao, M. W., Lai, M. J., Lin, M. H., Huang, H. L., Chang, C. D., Pan, S. L., Chen, M. C. & Liou, J. P., Sep 1 2020, In : European Journal of Medicinal Chemistry. 201, 112404.Research output: Contribution to journal › Comment/debate
Fluoropyrimidin-2,4-dihydroxy-5-isopropylbenzamides as antitumor agents against CRC and NSCLC cancer cells
Wu, W. C., Liu, Y. M., Liao, Y. H., Hsu, K. C., Lien, S. T., Chen, I. C., Lai, M. J., Li, Y. H., Pan, S. L., Chen, M. C. & Liou, J. P., Oct 1 2020, In : European Journal of Medicinal Chemistry. 203, 112540.Research output: Contribution to journal › Article
Functional analysis of Clostridium difficile sortase B reveals key residues for catalytic activity and substrate specificity
Kang, C. Y., Huang, I. H., Chou, C. C., Wu, T. Y., Chang, J. C., Hsiao, Y. Y., Cheng, C. H., Tsai, W. J., Hsu, K. C. & Wang, S., Mar 13 2020, In : Journal of Biological Chemistry. 295, 11, p. 3734-3745 12 p.Research output: Contribution to journal › Article
Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, C. F., Hsu, K. C., Huangfu, W. C., Lin, T. E., Huang, H. L. & Pan, S. L., Mar 12 2020, In : BMC Pharmacology and Toxicology. 21, 1, p. 21 21.Research output: Contribution to journal › Article
Open Access