Projects per year
Personal profile
Education
- 2011 國立交通大學生物資訊及系統生物研究所博士
- 2007 國立交通大學生物資訊研究所碩士
- 2005 國立交通大學生物科技學系學士
Experience
- 2018- 臺北醫學大學癌症生物學與藥物研發研究所助理教授
- 2015- 臺北醫學大學癌症生物學與藥物研發博士學位學程助理教授
- 2013-2015 國立交通大學約聘助理研究員
- 2011-2013 國立交通大學博士後研究員
Research Interests
- 生物學之生化及分子生物
- 生物資訊與醫療資訊
Fingerprint Dive into the research topics where Kai-Cheng Hsu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Proteins
Medicine & Life Sciences
Histone Deacetylases
Medicine & Life Sciences
Neuraminidase
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Inhibitory Concentration 50
Medicine & Life Sciences
Screening
Chemical Compounds
shikimate kinase
Medicine & Life Sciences
Autophagy
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2016 2020
針對癌症治療研發與活性最適化蛋白質激?抑制劑(1/3)
8/1/19 → 7/1/20
Project: A - Government Institution › b - Ministry of Science and Technology
藉由全方位探索新致病機制發現新的第2型糖尿病之肝臟治療靶點：基於慢性C型肝炎病毒感染模式到一般族群、連結基礎，生物信息學和臨床的系統性探討之轉譯研究-整合生物資訊方法研究C型肝炎誘發之第二型糖尿病的機轉與藥物開發(3/3)
8/1/19 → 7/1/20
Project: A - Government Institution › b - Ministry of Science and Technology
107大專生計畫獎-許凱程
8/1/18 → 7/31/19
Project: A - Government Institution › b - Ministry of Science and Technology
藉由全方位探索新致病機制發現新的第2型糖尿病之肝臟治療靶點：基於慢性C型肝炎病毒感染模式到一般族群、連結基礎，生物信息學和臨床的系統性探討之轉譯研究－整合生物資訊方法研究C型肝炎誘發之第二型糖尿病的機轉與藥物開發(2/3)
8/1/18 → 7/1/19
Project: A - Government Institution › b - Ministry of Science and Technology
研發與設計蛋白質激?抑制劑應用於癌症之治療
8/1/18 → 7/1/19
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output 2008 2019
5
Citations
(Scopus)
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase
Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.Research output: Contribution to journal › Article
Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide
Lee, C. C., Chang, W. H., Chang, Y. S., Yang, J. M., Chang, C. S., Hsu, K. C., Chen, Y. T., Liu, T. Y., Chen, Y. C., Lin, S. Y., Wu, Y. C. & Chang, J. G., Jan 1 2019, In : Molecular Oncology. 13, 8, p. 1744-1762 19 p.Research output: Contribution to journal › Article
Open Access
Pyrazines
Amiloride
Alternative Splicing
Neoplasms
RNA Sequence Analysis
Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells
Nepali, K., Lin, M. H., Chao, M. W., Peng, S. J., Hsu, K. C., Eight Lin, T., Chen, M. C., Lai, M. J., Pan, S. L. & Liou, J. P., Oct 1 2019, In : Bioorganic Chemistry. 91, 103119.Research output: Contribution to journal › Article
Growth Inhibitors
Amides
Prostatic Neoplasms
Cells
Lead compounds
2
Citations
(Scopus)
New paradigm of functional regulation by DNA mimic proteins: Recent updates
Wang, H. C., Chou, C. C., Hsu, K. C., Lee, C. H. & Wang, A. H. J., May 1 2019, In : IUBMB Life. 71, 5, p. 539-548 10 p.Research output: Contribution to journal › Review article
DNA
Charge distribution
Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Uracil-DNA Glycosidase
3
Citations
(Scopus)
Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirA vp and pirB vp toxins and activation of the cry-like pore-forming domain
Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., Apr 1 2019, In : Toxins. 11, 4, 233.Research output: Contribution to journal › Article
Open Access
Vibrio parahaemolyticus
Penaeidae
Chemical activation
Necrosis
Hepatopancreas