Projects per year
Personal profile
Education
- 2011 國立交通大學生物資訊及系統生物研究所博士
- 2007 國立交通大學生物資訊研究所碩士
- 2005 國立交通大學生物科技學系學士
Experience
- 2019- 臺北醫學大學癌症生物學與藥物研發研究所副教授
- 2019- 臺北醫學大學生技醫療產業研發博士學位學程副教授
- 2018- 臺北醫學大學癌症生物學與藥物研發研究所助理教授
- 2015- 臺北醫學大學癌症生物學與藥物研發博士學位學程助理教授
- 2013-2015 國立交通大學約聘助理研究員
- 2011-2013 國立交通大學博士後研究員
Research Interests
- 生物學之生化及分子生物
- 生物資訊與醫療資訊
Fingerprint
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Projects
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針對癌症治療研發與活性最適化蛋白質激酶抑制劑(2/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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建立新興環境汙染物與藥物毒理預測平台之研究
7/1/20 → 2/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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電腦輔助設計與研發新穎DYRK1B抑制劑
1/1/20 → 12/31/20
Project: A - Government Institution › d - Ministry of Education
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Design and Potency Optimization of Kinase Inhibitors for Cancer Treatment(1/3)
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
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Integrated Bioinformatics Approaches to Study the Mechanisms and Discover Drugs of Hcv-Induced Type 2 Diabetes Mellitus(3/3)
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output
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Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M. W., Lin, T. E., HuangFu, W. C., Chang, C. D., Tu, H. J., Chen, L. C., Yen, S. C., Sung, T. Y., Huang, W. J., Yang, C. R., Pan, S. L. & Hsu, K. C., Dec 2021, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 98-108 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
13-acetoxysarcocrassolide exhibits cytotoxic activity against oral cancer cells through the interruption of the keap1/Nrf2/p62/SQSTM1 pathway: The need to move beyond classical concepts
Liu, Y. C., Peng, B. R., Hsu, K. C., El-Shazly, M., Shih, S. P., Lin, T. E., Kuo, F. W., Chou, Y. C., Lin, H. Y. & Lu, M. C., Jul 23 2020, In : Marine Drugs. 18, 8, 382.Research output: Contribution to journal › Article › peer-review
Open Access -
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors
Hsu, K. C., HuangFu, W. C., Lin, T. E., Chao, M. W., Sung, T. Y., Chen, Y. Y., Pan, S. L., Lee, J. C., Tzou, S. C., Sun, C. M. & Yang, J. M., Jun 29 2020, In : Scientific Reports. 10, 1, p. 10510 10510.Research output: Contribution to journal › Article › peer-review
Open Access -
Biological Evaluation of Selected Flavonoids as Inhibitors of MNKs Targeting Acute Myeloid Leukemia
Chen, L. C., Huang, H. L., Huangfu, W. C., Yen, S. C., Ngo, S. T., Wu, Y. W., Lin, T. E., Sung, T. Y., Lien, S. T., Tseng, H. J., Pan, S. L., Huang, W. J. & Hsu, K. C., 2020, (Accepted/In press) In : Journal of Natural Products.Research output: Contribution to journal › Article › peer-review
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Corrigendum to“Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo”[Eur. J. Med. Chem. 190 (2020 Mar 15) 112086] (European Journal of Medicinal Chemistry (2020) 190, (S0223523420300532), (10.1016/j.ejmech.2020.112086))
Ojha, R., Nepali, K., Chen, C. H., Chuang, K. H., Wu, T. Y., Lin, T. E., Hsu, K. C., Chao, M. W., Lai, M. J., Lin, M. H., Huang, H. L., Chang, C. D., Pan, S. L., Chen, M. C. & Liou, J. P., Sep 1 2020, In : European Journal of Medicinal Chemistry. 201, 112404.Research output: Contribution to journal › Comment/debate › peer-review