Projects per year
Personal profile
Education
- 2011 國立交通大學生物資訊及系統生物研究所博士
- 2007 國立交通大學生物資訊研究所碩士
- 2005 國立交通大學生物科技學系學士
Experience
- 2019- Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019- Associate Professor, Ph.D. Program in Biotechnology Research and Development, Taipei Medical University
- 2018- Assistant Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2015- Assistant Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
Research Interests
- 生物學之生化及分子生物
- 生物資訊與醫療資訊
Fingerprint
Dive into the research topics where Kai-Cheng Hsu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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針對癌症治療研發與活性最適化蛋白質激酶抑制劑(3/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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探討pan-HDACs 抑制劑對抗藥性腦癌的抑制療效和作用機轉
7/1/21 → 2/28/22
Project: A - Government Institution › b - Ministry of Science and Technology
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電腦輔助設計與研發新穎DYRK1B抑制劑
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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針對癌症治療研發與活性最適化蛋白質激酶抑制劑(2/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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建立新興環境汙染物與藥物毒理預測平台之研究
7/1/20 → 2/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
Research output
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Discovery of a novel cyclin-dependent kinase 8 inhibitor with an oxindole core for anti-inflammatory treatment
Lin, T. E., Yang, C. R., Chou, C. H., Hsu, J. Y., Chao, M. W., Sung, T. Y., Hsieh, J. H., Huang, W. J. & Hsu, K. C., Feb 2022, In: Biomedicine and Pharmacotherapy. 146, 112459.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors
Lin, T. E., Sung, L. C., Chao, M. W., Li, M., Zheng, J. H., Sung, T. Y., Hsieh, J. H., Yang, C. R., Lee, H. Y., Cho, E. C. & Hsu, K. C., 2022, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 37, 1, p. 226-235 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo
Wu, Y. W., Chao, M. W., Tu, H. J., Chen, L. C., Hsu, K. C., Liou, J. P., Yang, C. R., Yen, S. C., HuangFu, W. C. & Pan, S. L., May 2021, In: Oncogenesis. 10, 5, 39.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling
Chang, T. Y., Nepali, K., Chen, Y. Y., Yang, Y. C. S. H., Hsu, K. C., Yen, Y., Pan, S. L., Liou, J. P. & Lee, S. B., Jun 2021, In: Biomedicine and Pharmacotherapy. 138, 111485.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes
Huang, K. F., Huang, J. S., Wu, M. L., Hsieh, W. L., Hsu, K. C., Hsu, H. L., Ko, T. P. & Wang, A. H. J., Jun 25 2021, In: Journal of Molecular Biology. 433, 13, 166960.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus)
Datasets
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CCDC 2000792: Experimental Crystal Structure Determination
Hsu, M. (Contributor), Hsieh, C. (Contributor), Kapoor, M. (Contributor), Chang, J. (Contributor), Chu, H. (Contributor), Cheng, T. (Contributor), Hsu, K. (Contributor), Lin, T. E. (Contributor), Tsai, F. (Contributor) & Horng, J. (Contributor), Unknown Publisher, May 1 2020
DOI: 10.5517/ccdc.csd.cc254zp0, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc254zp0&sid=DataCite
Dataset
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Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, C. (Contributor), Hsu, K. (Contributor), HuangFu, W. (Contributor), Lin, T. E. (Contributor), Huang, H. (Contributor) & Pan, S. (Contributor), Unknown Publisher, Mar 12 2020
DOI: 10.6084/m9.figshare.c.4896705.v1, https://doi.org/10.6084%2Fm9.figshare.c.4896705.v1
Dataset
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Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, C. (Contributor), Hsu, K. (Contributor), HuangFu, W. (Contributor), Lin, T. E. (Contributor), Huang, H. (Contributor) & Pan, S. (Contributor), Unknown Publisher, Mar 12 2020
DOI: 10.6084/m9.figshare.11992497.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Investigating_the_potential_effects_of_selective_histone_deacetylase_6_inhibitor_ACY1215_on_infarct_size_in_rats_with_cardiac_ischemia-reperfusion_injury/11992497/1
Dataset