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Research Output 2001 2019

  • 532 Citations
  • 13 h-Index
  • 37 Article
  • 2 Review article
  • 1 Chapter
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Article
2019
Adipogenesis
Protein Isoforms
White Adipocytes
Brown Adipose Tissue
3T3-L1 Cells
2 Citations (Scopus)

Effects of Chinese herbal medicine therapy on survival and hepatic outcomes in patients with hepatitis C virus infection in Taiwan

Tsai, F. J., Cheng, C. F., Chen, C. J., Lin, C. Y., Wu, Y. F., Li, T. M., Chuang, P. H., Wu, Y. C., Lai, C. H., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, J. C., Lin, C. C., Liang, W. M. & Lin, Y. J., Apr 1 2019, In : Phytomedicine. 57, p. 30-38 9 p.

Research output: Contribution to journalArticle

Phytotherapy
Herbal Medicine
Virus Diseases
Taiwan
Hepacivirus
2 Citations (Scopus)

Protective effects and network analysis of natural compounds obtained from Radix dipsaci, Eucommiae cortex, and Rhizoma drynariae against RANKL-induced osteoclastogenesis in vitro

Cheng, C. F., Chien-Fu Lin, J., Tsai, F. J., Chen, C. J., Chiou, J. S., Chou, C. H., Li, T. M., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, J. C., Lin, C. C., Ban, B., Liang, W. M. & Lin, Y. J., Nov 15 2019, In : Journal of Ethnopharmacology. 244, 112074.

Research output: Contribution to journalArticle

Open Access
Polypodiaceae
Herbal Medicine
Osteogenesis
Bone Diseases
Hip Fractures
Hypoxia-Inducible Factor 1
RNA-Binding Proteins
Alternative Splicing
Lung Neoplasms
Protein Isoforms
2018
6 Citations (Scopus)

Characteristics of Chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan

Li, T. M., Yu, Y. H., Tsai, F. J., Cheng, C. F., Wu, Y. C., Ho, T. J., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, J. C., Lin, C. C., Liang, W. M. & Lin, Y. J., Mar 1 2018, In : Journal of Ethnopharmacology. 213, p. 92-100 9 p.

Research output: Contribution to journalArticle

Herbal Medicine
Taiwan
Lung Neoplasms
Survival
Prescriptions
4 Citations (Scopus)

Effects of Chinese herbal medicine on hyperlipidemia and the risk of cardiovascular disease in HIV-infected patients in Taiwan

Tsai, F. J., Li, T. M., Cheng, C. F., Wu, Y. C., Lai, C. H., Ho, T. J., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, J. C., Lin, C. C., Liang, W. M. & Lin, Y. J., Jun 12 2018, In : Journal of Ethnopharmacology. 219, p. 71-80 10 p.

Research output: Contribution to journalArticle

Herbal Medicine
Hyperlipidemias
Taiwan
Cardiovascular Diseases
HIV

Evaluation of oral antiretroviral drugs in mice with metabolic and neurologic complications

Tsai, F. J., Ho, M. W., Lai, C. H., Chou, C. H., Li, J. P., Cheng, C. F., Wu, Y. C., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Lin, J. C., Lin, C. C., Hsieh, C. L., Liang, W. M. & Lin, Y. J., Sep 4 2018, In : Frontiers in Pharmacology. 9, SEP, 1004.

Research output: Contribution to journalArticle

Reverse Transcriptase Inhibitors
Nervous System
Nucleosides
Pharmaceutical Preparations
Protease Inhibitors
3 Citations (Scopus)
Adipogenesis
Protein Kinases
Exons
Brown Adipocytes
RNA Sequence Analysis
1 Citation (Scopus)
Brown Adipocytes
Alternative Splicing
Brown Adipose Tissue
Protein Isoforms
Adipogenesis
3 Citations (Scopus)

RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis

Peng, H. Y., Liang, Y. C., Tan, T. H., Chuang, H. C., Lin, Y. J. & Lin, J. C., Sep 6 2018, In : International Journal of Molecular Sciences. 19, 9, 2646.

Research output: Contribution to journalArticle

Brown Adipocytes
Adipogenesis
splicing
RNA
cascades
5 Citations (Scopus)

RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell

Lin, J. C., Lee, Y. C., Tan, T. H., Liang, Y. C., Chuang, H. C., Fann, Y. C., Johnson, K. R. & Lin, Y. J., Feb 1 2018, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1865, 2, p. 259-272 14 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Colorectal Neoplasms
Mitogen-Activated Protein Kinase 8
Cadherins
Alternative Splicing
2017
5 Citations (Scopus)

Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts

Tsai, F. J., Ho, T. J., Cheng, C. F., Shiao, Y. T., Chien, W. K., Chen, J. H., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, C. W., Lin, J. G., Lan, Y. C., Liu, Y. H., Hung, C. H., Lin, J. C., Lin, C. C., Lai, C. H. & 2 others, Liang, W. M. & Lin, Y. J., 2017, In : Oncotarget. 8, 9, p. 15470-15489 20 p.

Research output: Contribution to journalArticle

Herbal Medicine
Type 2 Diabetes Mellitus
Hydrogen Peroxide
Myocardial Ischemia
Apoptosis
5 Citations (Scopus)

Effect of antiretroviral therapy use and adherence on the risk of hyperlipidemia among HIV-infected patients, in the highly active antiretroviral therapy era

Tsai, F. J., Cheng, C. F., Lai, C. H., Wu, Y. C., Ho, M. W., Wang, J. H., Tien, N., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, J. C., Lin, C. C., Chen, J. H., Liang, W. M. & Lin, Y. J., Jan 1 2017, In : Oncotarget. 8, 63, p. 106369-106381 13 p.

Research output: Contribution to journalArticle

Highly Active Antiretroviral Therapy
Hyperlipidemias
HIV
Protease Inhibitors
Therapeutics
10 Citations (Scopus)

Effect of Chinese herbal medicine on stroke patients with type 2 diabetes

Tsai, F. J., Ho, T. J., Cheng, C. F., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, C. W., Lin, J. G., Lin, J. C., Lin, C. C., Liang, W. M. & Lin, Y. J., Mar 22 2017, In : Journal of Ethnopharmacology. 200, p. 31-44 14 p.

Research output: Contribution to journalArticle

Herbal Medicine
Type 2 Diabetes Mellitus
Stroke
Salvia miltiorrhiza
Qi
6 Citations (Scopus)

Effects of Chinese herbal medicines on the occurrence of diabetic retinopathy in type 2 diabetes patients and protection of ARPE-19 retina cells by inhibiting oxidative stress

Tsai, F. J., Li, T. M., Ko, C. H., Cheng, C. F., Ho, T. J., Liu, X., Tsang, H., Lin, T. H., Liao, C. C., Li, J. P., Huang, S. M., Lin, J. C., Lin, C. C., Liang, W. M. & Lin, Y. J., 2017, In : Oncotarget. 8, 38, p. 63528-63550 23 p.

Research output: Contribution to journalArticle

Herbal Medicine
Diabetic Retinopathy
Type 2 Diabetes Mellitus
Retina
Oxidative Stress
3 Citations (Scopus)

KCNQ1 variants associate with hypertension in type 2 diabetes and affect smooth muscle contractility in vitro

Huang, K. C., Li, T. M., Liu, X., Chen, J. H., Chien, W. K., Shiao, Y. T., Tsang, H., Lin, T. H., Liao, C. C., Huang, S. M., Li, J. P., Lin, C. W., Lin, J. C., Lin, C. C., Lai, C. H., Cheng, C. F., Liang, W. M., Hung, C. H., Chen, C. C., Lin, Y. J. & 1 others, Tsai, F. J., 2017, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Medical problems
Type 2 Diabetes Mellitus
Smooth Muscle
Muscle
Hypertension
3 Citations (Scopus)

The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells

Lin, J. C., Lee, Y. C., Liang, Y. C., Fann, Y. C., Johnson, K. R. & Lin, Y. J., Mar 9 2017, In : Scientific Reports. 7, 44204.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Introns
Alternative Splicing
RNA
RNA Sequence Analysis
2016
9 Citations (Scopus)

RBM4a-regulated splicing cascade modulates the differentiation and metabolic activities of brown adipocytes

Lin, J. C., Lu, Y. H., Liu, Y. R. & Lin, Y. J., Feb 9 2016, In : Scientific Reports. 6, 20665.

Research output: Contribution to journalArticle

Brown Adipocytes
RNA-Binding Proteins
MEF2 Transcription Factors
Genes
RNA Sequence Analysis
10 Citations (Scopus)

RBM4–Nova1–SRSF6 splicing cascade modulates the development of brown adipocytes

Lin, J. C., Chi, Y. L., Peng, H. Y. & Lu, Y. H., Nov 1 2016, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 11, p. 1368-1379 12 p.

Research output: Contribution to journalArticle

Brown Adipocytes
Alternative Splicing
Adipogenesis
Introns
Exons
2015
8 Citations (Scopus)

Analysis of differentially expressed novel post-translational modifications of plasma apolipoprotein E in Taiwanese females with breast cancer

Uen, Y. H., Liao, C. C., Lin, J. C., Pan, Y. H., Liu, Y. C., Chen, Y. C., Chen, W. J., Tai, C. C., Lee, K. W., Liu, Y. R., Lin, H. T. & Lin, C. Y., Aug 3 2015, In : Journal of Proteomics. 126, p. 252-262 11 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Post Translational Protein Processing
Breast Neoplasms
Plasmas
Methylation
16 Citations (Scopus)

Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan

Lin, Y. J., Chang, J. S., Liu, X., Tsang, H., Chien, W. K., Chen, J. H., Hsieh, H. Y., Hsueh, K. C., Shiao, Y. T., Li, J. P., Lin, C. W., Lai, C. H., Wu, J. Y., Chen, C. H., Lin, J. G., Lin, T. H., Liao, C. C., Huang, S. M., Lan, Y. C., Ho, T. J. & 4 others, Liang, W. M., Yeh, Y. C., Lin, J. C. & Tsai, F. J., Oct 5 2015, In : Scientific Reports. 5, 14762.

Research output: Contribution to journalArticle

Coronary Aneurysm
Mucocutaneous Lymph Node Syndrome
Taiwan
Coronary Vessels
Type C Phospholipases
8 Citations (Scopus)

Impacts of alternative splicing events on the differentiation of adipocytes

Lin, J. C., Sep 14 2015, In : International Journal of Molecular Sciences. 16, 9, p. 22169-22189 21 p.

Research output: Contribution to journalArticle

splicing
Alternative Splicing
RNA
Adipocytes
Genes
3 Citations (Scopus)
Photobacterium
Staphylococcal Protein A
Bacteriophages
Shock
Peptides
11 Citations (Scopus)

RBM4-MEF2C network constitutes a feed-forward circuit that facilitates the differentiation of brown adipocytes

Lin, J. C., 2015, In : RNA Biology. 12, 2, p. 208-220 13 p.

Research output: Contribution to journalArticle

MEF2 Transcription Factors
Brown Adipocytes
Protein Isoforms
Transcriptome
Myocardium
13 Citations (Scopus)
RNA-Binding Proteins
Polypyrimidine Tract-Binding Protein
Colorectal Neoplasms
Alternative Splicing
Carcinogenesis
2014
35 Citations (Scopus)

Elevated SRPK1 lessens apoptosis in breast cancer cells through RBM4-regulated splicing events

Lin, J. C., Lin, C. Y., Tarn, W. Y. & Li, F. Y., Oct 1 2014, In : RNA. 20, 10, p. 1621-1631 11 p.

Research output: Contribution to journalArticle

Arginine Kinase
RNA-Binding Proteins
Serine
Apoptosis
Breast Neoplasms
18 Citations (Scopus)

Emerging role for RNA binding motif protein 4 in the development of brown adipocytes

Lin, J. C., Tarn, W. Y. & Hsieh, W. K., Apr 2014, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 4, p. 769-779 11 p.

Research output: Contribution to journalArticle

Brown Adipocytes
RNA-Binding Proteins
Adipocytes
Uncoupling Agents
White Adipocytes
2013
25 Citations (Scopus)

RBM4 promotes pancreas cell differentiation and insulin expression

Lin, J. C., Yan, Y. T., Hsieh, W. K., Peng, P. J., Su, C. H. & Tarna, W. Y., Jan 2013, In : Molecular and Cellular Biology. 33, 2, p. 319-327 9 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Cell Differentiation
Pancreas
Insulin
Alternative Splicing
2012
10 Citations (Scopus)

Multiple roles of RBM4 in muscle cell differentiation

Lin, J. C. & Tarn, W. Y., Jan 1 2012, In : Frontiers in Bioscience - Scholar. 4 S, 1, p. 181-189 9 p.

Research output: Contribution to journalArticle

Muscle Cells
Muscle
Cell Differentiation
Cells
RNA
2011
41 Citations (Scopus)

RBM4 down-regulates PTB and antagonizes its activity in muscle cell-specific alternative splicing

Lin, J. C. & Tarn, W. Y., May 2011, In : Journal of Cell Biology. 193, 3, p. 509-520 12 p.

Research output: Contribution to journalArticle

Alternative Splicing
Muscle Cells
Down-Regulation
Exons
Muscle Development
2009
29 Citations (Scopus)
Cytoplasmic Granules
RNA-Binding Proteins
Cell Differentiation
RNA
Muscle
2007
61 Citations (Scopus)
Protein Splicing
RNA-Binding Proteins
Phosphorylation
RNA-Binding Motifs
Peptide Initiation Factors
2006
23 Citations (Scopus)

The immediate early 2 protein of human cytomegalovirus (HCMV) mediates the apoptotic control in HCMV retinitis through up-regulation of the cellular FLICE-inhibitory protein expression

Chiou, S. H., Yang, Y. P., Lin, J. C., Hsu, C. H., Jhang, H. C., Yang, Y. T., Lee, C. H., Ho, L. L. T., Hsu, W-M., Ku, H. H., Chen, S. J., Chen, S. S. L., Chang, M. D. T., Wu, C. W. & Juan, L. J., Nov 1 2006, In : Journal of Immunology. 177, 9, p. 6199-6206 8 p.

Research output: Contribution to journalArticle

CASP8 and FADD-Like Apoptosis Regulating Protein
Immediate-Early Proteins
Cytomegalovirus Retinitis
Cytomegalovirus
Up-Regulation
2005
56 Citations (Scopus)

Exon selection in α-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB

Lin, J. C. & Tarn, W. Y., Nov 2005, In : Molecular and Cellular Biology. 25, 22, p. 10111-10121 11 p.

Research output: Contribution to journalArticle

Polypyrimidine Tract-Binding Protein
Tropomyosin
RNA-Binding Proteins
Exons
Messenger RNA
2002
15 Citations (Scopus)

Apoptosis of human retina and retinal pigment cells induced by human cytomegalovirus infection

Chiou, S. H., Liu, J. H., Chen, S. S. L., Liu, W. T., Lin, J. C., Wong, W. W., Tseng, W. S., Chou, C. K., Liu, C. Y., Ho, L. L. T. & Hsu, W-M., 2002, In : Ophthalmic Research. 34, 2, p. 77-82 6 p.

Research output: Contribution to journalArticle

Retinal Pigments
Cytomegalovirus Infections
Retina
Apoptosis
Acquired Immunodeficiency Syndrome
26 Citations (Scopus)

Nitric oxide levels in the aqueous humor in cataract patients

Kao, C. L., Chou, C. K., Tsai, D. C., Hsu, W-M., Liu, J. H., Wang, C. S., Lin, J. C., Wu, C. C., Peng, C. H., Chang, C. J., Kao, C. L. & Chiou, S. H., 2002, In : Journal of Cataract and Refractive Surgery. 28, 3, p. 507-512 6 p.

Research output: Contribution to journalArticle

Aqueous Humor
Cataract
Nitric Oxide
Taiwan
Age Groups
2001
48 Citations (Scopus)

Up-regulation of Fas ligand expression by human cytomegalovirus immediate-early gene product 2: A novel mechanism in cytomegalovirus-induced apoptosis in human retina

Chiou, S. H., Liu, J. H., Hsu, W-M., Chen, S. S. L., Chang, S. Y., Juan, L. J., Lin, J. C., Yang, Y. T., Wong, W. W., Liu, C. Y., Lin, Y. S., Liu, W. T. & Wu, C. W., Oct 1 2001, In : Journal of Immunology. 167, 7, p. 4098-4103 6 p.

Research output: Contribution to journalArticle

Immediate-Early Genes
Fas Ligand Protein
Cytomegalovirus
Retina
Up-Regulation