Jing-Ping Liou

Projects

Projects per year 2013 2014 2015 2016 2018 2019 2020 2021 2022 2023

• 2 Active
• 30 Finished

Projects per year

Search results

• Active

  Organopalladium Assisted Stitching of Key Antitumor Fragments to Furnish Dual Inhibitory Anticancer Chemical Architectures( II )

  Liou, J.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Discovery of Bbb-Crossing Drugs Targeting Neuroinflammation for Glioblastoma( I )

  Liou, J.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology
• Finished

  設計與合成雙效LSD1/HDAC抑制劑作為抗大腸直腸癌之研究

  Liou, J.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 合成用於治療腦癌的前列腺素E2抑制劑

  Liou, J.

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 代謝質體研究所引發的抗腦癌藥物研發

  Liou, J.

  1/1/22 → 12/31/22

  Project: A - Government Institution › f - Other (Funded by Government)

• 有機鈀金屬促進關鍵抗腫瘤片段的縫合以建構雙功能抗癌化學結構(1/3)

  Liou, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Design and synthesis of novel dual EZH2 and HSP90 inhibitor

  Liou, J.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發阻斷神經類固醇生合成與雄性素接受器活性的新穎藥物以避免癌症抗藥性

  Liou, J.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 有機金屬催化反應於合成化學和藥物化學之抗癌表觀遺傳學抑制劑研究(2/2)

  Liou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Lysine-specific histone demethylase 1 抑制劑的研發

  Liou, J.

  2/1/20 → 1/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發阻斷神經類固醇生合成與雄性素接受器活性的新穎藥物以避免癌症抗藥性

  Liou, J.

  1/1/20 → 12/31/20

  Project: A - Government Institution › d - Ministry of Education

• Synthetic and Medicinal Utility of Organometallics in the Development of Anticancer Epigenetic Inhibitors: Applications and Explorations( I )( I )(1/2)

  Liou, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展抗肺纖維化劑-合成抗肺纖維化合物

  Liou, J.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 亞太生醫矽谷精準醫療旗艦計畫-臺北醫學大學合作案

  Liou, J.

  1/1/19 → 12/1/19

  Project: A - Government Institution › a - National Health Research Institutes

• The Use of Organometallic Reaction in the Syntheses of Anticancer Agents(2/2)

  Liou, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗肺癌標靶化合物的合成(2/2)

  Liou, J.

  6/1/18 → 5/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展抗肺纖維化劑

  Liou, J.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › h - Higher Education Sprout Project

• The Use of Organometallic Reaction in the Syntheses of Anticancer Agents.( I )

  Liou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antineoplastic Agent 100%
  • Chan-Lam Coupling 96%
  • Buchwald-Hartwig Cross Coupling Reaction 79%
  • Ullmann Reaction 76%
  • Alkynylation 75%

• Syntheses of Anti-Lung Cancer Agents(1/2)

  Liou, J.

  6/1/17 → 5/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Crizotinib 100%
  • Alectinib 59%
  • Ceritinib 55%
  • Drug 29%

• Application of Regioselective Substitution on 1,4-Benzoquinone Derivatives to Provide Potent Anticancer Agents(3/3)

  Liou, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1,4-benzoquinone 100%
  • Wittig Olefination 54%
  • Intramolecular Cyclization 40%
  • Nucleophilic Substitution 38%
  • Regioselectivity 35%

• 小分子抗前列腺癌之藥物研發

  Liou, J.

  6/1/16 → 4/30/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗癌標靶化合物的合成

  Liou, J.

  5/1/16 → 4/30/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 合成選擇性HDAC6?抑制劑

  Liou, J.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Service for Sharing Precious Instruments of Taipei Medical University

  Chen, Y., Liou, J. & Chien, L.

  12/1/15 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Reservation systems 100%
  • Mass spectrometers 91%
  • Nuclear magnetic resonance 77%
  • Magnetic resonance spectrometers 60%
  • Online systems 38%

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (II)

  Liou, J.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Regioselective Substitution on 1,4-Benzoquinone Derivatives to Provide Potent Anticancer Agents

  Liou, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1,4-benzoquinone 100%
  • Wittig Olefination 54%
  • Intramolecular Cyclization 40%
  • Nucleophilic Substitution 38%
  • Regioselectivity 35%

• Syntheses of Selective Histone Deacetylase 6 inhibitors

  Liou, J.

  1/1/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Histone 100%
  • Tubastatin A 97%
  • Antiproliferative 46%
  • Enzyme Activity 38%
  • Bioactivity 33%

• A Phase I, First-In-Human, Dose-Seeking Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Orally Administered MPT0E028 in Subjects with Advanced Solid Malignancies without Standard Treatment (I)

  Liou, J.

  9/1/14 → 9/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 100%
  • Histones 39%
  • Vorinostat 30%
  • Erlotinib Hydrochloride 27%
  • Sorafenib 26%

• Application of Regioselective Substitution on 1,4-Benzoquinone Derivatives to Provide Potent Anticancer Agents

  Liou, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1,4-benzoquinone 100%
  • Wittig Olefination 54%
  • Intramolecular Cyclization 40%
  • Nucleophilic Substitution 38%
  • Regioselectivity 35%

• Syntheses of Selective Histone Deacetylase 6 inhibitors

  Liou, J.

  1/1/14 → 12/31/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Histone 100%
  • Tubastatin A 97%
  • Antiproliferative 93%
  • Enzyme Activity 38%
  • Bioactivity 33%

• Use the organometal catalytic reaction to synthesize the heterocycle-based anticancer agents

  Liou, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antineoplastic Agent 100%
  • Hydroxyl 93%
  • Antiproliferative 56%
  • Antitumor 52%
  • Structure-Activity Relationship 48%

• 開發雜環類之組織蛋白去乙醯抑制劑為抗癌藥物(3/3)

  Liou, J.

  5/1/13 → 4/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology