Projects per year
Personal profile
Education
- 1994 B.S., School of Pharmacy, Taipei Medical University
- 1996 M.S., Graduate Institute of Pharmaceutical Sciences, National Taiwan University
- 2000 Ph.D., Graduate Institute of Pharmaceutical Sciences, National Taiwan University
Experience
Professional Experiences:
- 2013- Jointly Appointed Professor, Ph.D. Program in Clinical Drug Development of Herbal Medicine, College of Pharmacy, Taipei Medical University
- 2013- Jointly Appointed Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2012- Professor, School of Pharmacy, College of Pharmacy, Taipei Medical University
- 2008-2012 Associate Professor, School of Pharmacy, College of Pharmacy, Taipei Medical University
- 2004-2008 Assistant Professor, School of Pharmacy, College of Pharmacy, Taipei Medical University
- 2000-2004 Postdoctoral Research, Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes
Administrative experiences:
- 2018- Dean, College of Pharmacy, Taipei Medical University
- 2017- Director, Biomedical Commercialization Center, Taipei Medical University
- 2015- Director, Research Center of Pharmaceutical Sciences and Biotechnology, College of Pharmacy, Taipei Medical University
- 2013-2017 Associate Dean, College of Pharmacy, Taipei Medical University
- 2012-2016 Director, Core Laboratory of Drug Organic Synthesis, Taipei Medical University
Awards
1. EDITORIAL ADVISORY BOARD members, Journal of Medicinal Chemistry (IF = 6.259, CHEMISTRY/MEDICINAL)
2. 2015 Taipei Medical University Teaching Award
3. 2014 Taipei Biotech Awards, Gold “Industry-University Cooperation Award”
4. 2014 TienTe Lee Award, Young Scientist Award
5. 2011 Young scientist award, Ching-Kang Foundation for Pharmacy Promotion
Research Interests
- Discovery and Development of small molecular compounds towards IND
- Structure optimization through rational drug design and intelligent modification
- Medicinal Chemistry
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 10 Similar Profiles
Tubulin Modulators
Medicine & Life Sciences
Tubulin
Medicine & Life Sciences
Histone Deacetylase Inhibitors
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Histone Deacetylases
Medicine & Life Sciences
Inhibitory Concentration 50
Medicine & Life Sciences
Antimitotic Agents
Medicine & Life Sciences
Antineoplastic Agents
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2019
運用有機金屬偶聯反應於抗癌試劑合(2/2)
8/1/18 → 7/31/19
Project: A - Government Institution › b - Ministry of Science and Technology
運用有機金屬偶聯反應於抗癌試劑合成(1/2)
8/1/17 → 7/31/18
Project: A - Government Institution › b - Ministry of Science and Technology
Syntheses of Anti-Lung Cancer Agents(1/2)
6/1/17 → 5/31/18
Project: A - Government Institution › b - Ministry of Science and Technology
1,4-Benzoquinone之位向選擇性取代應用於抗癌試劑研發(3/3)
8/1/16 → 7/31/17
Project: A - Government Institution › b - Ministry of Science and Technology
105大專生計畫獎-劉景平
8/1/16 → 7/31/17
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output 1996 2019
1
Citation
(Scopus)
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase
Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.Research output: Contribution to journal › Article
Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
4
Citations
(Scopus)
Nitro-Group-Containing Drugs
Nepali, K., Lee, H. Y. & Liou, J. P., Mar 28 2019, In : Journal of Medicinal Chemistry. 62, 6, p. 2851-2893 43 p.Research output: Contribution to journal › Review article
Antitubercular Agents
Antiparasitic Agents
Pharmaceutical Chemistry
Prodrugs
Therapeutic Uses
Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents
Liu, Y-M., Chen, C-H., Yeh, T-K. & Liou, J-P., Feb 21 2019, In : Future Medicinal Chemistry.Research output: Contribution to journal › Article
Urinary Bladder Neoplasms
Antineoplastic Agents
G1 Phase
Ovarian Neoplasms
Solubility
9
Citations
(Scopus)
(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo
Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.Research output: Contribution to journal › Article
Quinolines
Histone Deacetylase Inhibitors
Multiple Myeloma
Growth
Hydroxamic Acids
3
Citations
(Scopus)
1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC
Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., Apr 25 2018, In : European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.Research output: Contribution to journal › Article
Hydroxamic Acids
Histone Deacetylase Inhibitors
Antineoplastic Agents
Protein Isoforms
Cells