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Personal profile

Education

  • 1994 B.S., School of Pharmacy, Taipei Medical University
  • 1996 M.S., Graduate Institute of Pharmaceutical Sciences, National Taiwan University
  • 2000 Ph.D., Graduate Institute of Pharmaceutical Sciences, National Taiwan University

Experience

Professional Experiences:

  • 2013- Jointly Appointed Professor, Ph.D. Program in Clinical Drug Development of Herbal Medicine, College of Pharmacy, Taipei Medical University
  • 2013- Jointly Appointed Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
  • 2012- Professor, School of Pharmacy, College of Pharmacy, Taipei Medical University
  • 2008-2012 Associate Professor, School of Pharmacy, College of Pharmacy, Taipei Medical University
  • 2004-2008 Assistant Professor, School of Pharmacy, College of Pharmacy, Taipei Medical University
  • 2000-2004 Postdoctoral Research, Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes

Administrative experiences:

  • 2018- Dean, College of Pharmacy, Taipei Medical University
  • 2017- Director, Biomedical Commercialization Center, Taipei Medical University
  • 2015- Director, Research Center of Pharmaceutical Sciences and Biotechnology, College of Pharmacy, Taipei Medical University
  • 2013-2017 Associate Dean, College of Pharmacy, Taipei Medical University
  • 2012-2016 Director, Core Laboratory of Drug Organic Synthesis, Taipei Medical University

Awards

1. EDITORIAL ADVISORY BOARD members, Journal of Medicinal Chemistry (IF = 6.259, CHEMISTRY/MEDICINAL)
2. 2015 Taipei Medical University Teaching Award
3. 2014 Taipei Biotech Awards, Gold “Industry-University Cooperation Award”
4. 2014 TienTe Lee Award, Young Scientist Award
5. 2011 Young scientist award, Ching-Kang Foundation for Pharmacy Promotion

Research Interests

  1. Discovery and Development of small molecular compounds towards IND
  2. Structure optimization through rational drug design and intelligent modification
  3. Medicinal Chemistry

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2019

運用有機金屬偶聯反應於抗癌試劑合(2/2)

Liou, J.

8/1/187/31/19

Project: A - Government Institutionb - Ministry of Science and Technology

運用有機金屬偶聯反應於抗癌試劑合成(1/2)

Liou, J.

8/1/177/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Syntheses of Anti-Lung Cancer Agents(1/2)

Liou, J.

6/1/175/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

1,4-Benzoquinone之位向選擇性取代應用於抗癌試劑研發(3/3)

Liou, J.

8/1/167/31/17

Project: A - Government Institutionb - Ministry of Science and Technology

105大專生計畫獎-劉景平

Liou, J.

8/1/167/31/17

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 1996 2019

  • 2471 Citations
  • 27 h-Index
  • 114 Article
  • 3 Review article
1 Citation (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
4 Citations (Scopus)

Nitro-Group-Containing Drugs

Nepali, K., Lee, H. Y. & Liou, J. P., Mar 28 2019, In : Journal of Medicinal Chemistry. 62, 6, p. 2851-2893 43 p.

Research output: Contribution to journalReview article

Antitubercular Agents
Antiparasitic Agents
Pharmaceutical Chemistry
Prodrugs
Therapeutic Uses
Urinary Bladder Neoplasms
Antineoplastic Agents
G1 Phase
Ovarian Neoplasms
Solubility
9 Citations (Scopus)

(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo

Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.

Research output: Contribution to journalArticle

Quinolines
Histone Deacetylase Inhibitors
Multiple Myeloma
Growth
Hydroxamic Acids
3 Citations (Scopus)

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., Apr 25 2018, In : European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.

Research output: Contribution to journalArticle

Hydroxamic Acids
Histone Deacetylase Inhibitors
Antineoplastic Agents
Protein Isoforms
Cells