If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

  • Neuroprotection
  • Brain cancer stem cell
  • Drug addiction


  • 2010, Ph.D., National Cheng-Kung University, Taiwan
  • 2004, M.S., Chang-Gung University, Taiwan
  • 2002, B.S., Kaohsiung Medical University, Taiwan


  • 2013 Assistant Professor, Taipei Medical University
  • 2011 Postdoctoral Fellow, National Institute on Drug Abuse, NIH, U.S.A.
  • 2010 Postdoctoral Fellow, National Cheng-Kung University, Tainan, Taiwan
  • 2009 Visiting Scholar, National Institute on Drug Abuse, NIH, , U.S.A
  • 2004 Research Assistant, Chang-Gung University, Taiwan



  • 2013 National Institutes of Health, Fellows Award for Research Excellence (FARE) 2013 winner
  • 2010 National Cheng Kung University, Excellent Research Award
  • 2009 The 17th International Symposium on Recent Advances in Cellular and Molecula Biology, Dr. Chien-Tien Hsu’ Award for Outstanding Dissertation
  • 2008 National Cheng Kung University, Excellent Research Award


Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 1 Similar Profiles
Cocaine Medicine & Life Sciences
temozolomide Medicine & Life Sciences
Proteins Medicine & Life Sciences
Human Herpesvirus 4 Medicine & Life Sciences
Mitosis Medicine & Life Sciences
Glioma Medicine & Life Sciences
Dentate Gyrus Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2018

Research Output 2003 2018

  • 759 Citations
  • 16 h-Index
  • 43 Article

Ephexin1 is required for Eph-Mediated limb trajectory of spinal motor axons

Chang, C. J., Chang, M. Y., Chou, S. Y., Huang, C. C., Chuang, J. Y., Hsu, T. I., Chang, H. F., Wu, Y. H., Wu, C. C., Morales, D., Kania, A. & Kao, T. J. Feb 21 2018 In : Journal of Neuroscience. 38, 8, p. 2043-2056 14 p.

Research output: Contribution to journalArticle

Motor Neurons
Spinal Cord
1 Citations

Improved effects of honokiol on temozolomide-induced autophagy and apoptosis of drug-sensitive and -tolerant glioma cells

Chio, C. C., Chen, K. Y., Chang, C. K., Chuang, J. Y., Liu, C. C., Liu, S. H. & Chen, R. M. Apr 3 2018 In : BMC Cancer. 18, 1, 379

Research output: Contribution to journalArticle

Pharmaceutical Preparations
2 Citations
Stem Cells
1 Citations

1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4 H -indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine

Chao, P. K., Ueng, S. H., Ou, L. C., Yeh, T. K., Chang, W. T., Chang, H. F., Chen, S. C., Tao, P. L., Law, P. Y., Loh, H. H., Cheng, M. F., Chuang, J. Y., Chen, C. T., Shih, C. & Yeh, S. H. May 1 2017 In : Anesthesiology. 126, 5, p. 952-966 15 p.

Research output: Contribution to journalArticle

Opioid Receptors
Opioid Analgesics
Surgical Instruments
2 Citations

Mapping the naloxone binding sites on the mu-opioid receptor using cell-based photocrosslinkers

Ke, Y. Y., Huang, Y. H., Chien, W. C., Loh, H. H., Chuang, J. Y. & Yeh, S. H. Mar 1 2017 In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1865, 3, p. 336-343 8 p.

Research output: Contribution to journalArticle

mu Opioid Receptor
Binding Sites