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Personal profile


  • 2010 Ph.D., National Cheng-Kung University, Taiwan
  • 2004 M.S., Chang-Gung University, Taiwan
  • 2002 B.S., Kaohsiung Medical University, Taiwan


  • 2017- Associate Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
  • 2013-2017 Assistant Professor,The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
  • 2011 Postdoctoral Fellow, National Institute on Drug Abuse, NIH, U.S.A.
  • 2010 Postdoctoral Fellow, National Cheng-Kung University, Tainan, Taiwan
  • 2009 Visiting Scholar, National Institute on Drug Abuse, NIH, , U.S.A
  • 2004 Research Assistant, Chang-Gung University, Taiwan



  • 2013 National Institutes of Health, Fellows Award for Research Excellence (FARE) 2013 winner
  • 2010 National Cheng Kung University, Excellent Research Award
  • 2009 The 17th International Symposium on Recent Advances in Cellular and Molecula Biology, Dr. Chien-Tien Hsu’ Award for Outstanding Dissertation
  • 2008 National Cheng Kung University, Excellent Research Award

Research Interests

  • Neuroprotection
  • Brain cancer stem cell
  • Drug addiction


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Chuang, J.


Project: C - Project of Allianceo - Chi Mei Medical Center

Investigating Nerve Regeneration Following Traumatic Brain Injury( I )

Chuang, J.


Project: A - Government Institutionb - Ministry of Science and Technology

HDAC6 藉由稳定膠質母细胞瘤中的雄激素受體表達來調節RAD51促進治療抗藥性發展

Chuang, J.


Project: A - Government Institutiond - Ministry of Education


Chuang, J.


Project: C - Project of Alliancen - Yuan's General Hospital

Research Output

  • 1032 Citations
  • 18 h-Index
  • 58 Article
  • 1 Conference contribution

AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis

Chen, T. C., Chuang, J. Y., Ko, C. Y., Kao, T. J., Yang, P. Y., Yu, C. H., Liu, M. S., Hu, S. L., Tsai, Y. T., Chan, H., Chang, W. C. & Hsu, T. I., Feb 1 2020, In : Redox Biology. 30, p. 101413 101413.

Research output: Contribution to journalArticle

Open Access
  • 1 Citation (Scopus)

    Betulinic acid-mediated tuning of PERK/CHOP signaling by sp1 inhibition as a novel therapeutic strategy for glioblastoma

    Lo, W. L., Hsu, T. I., Yang, W. B., Kao, T. J., Wu, M. H., Huang, Y. N., Yeh, S. H. & Chuang, J. Y., Apr 2020, In : Cancers. 12, 4, 981.

    Research output: Contribution to journalArticle

    Open Access
  • BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine

    Chao, P. K., Chang, H. F., Chang, W. T., Yeh, T. K., Ou, L. C., Chuang, J. Y., Tsu-An Hsu, J., Tao, P. L., Loh, H. H., Shih, C., Ueng, S. H. & Yeh, S. H., Apr 1 2020, In : Neuropharmacology. 166, 107678.

    Research output: Contribution to journalArticle

  • 3 Citations (Scopus)

    Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma

    Yang, W-B., Hsu, C-C., Hsu, T-I., Liou, J-P., Chang, K-Y., Chen, P-Y., Liu, J-J., Yang, S-T., Wang, J-Y., Yeh, S-H., Chen, R-M., Chang, W-C. & Chuang, J-Y., Apr 24 2020, In : Neuro-Oncology.

    Research output: Contribution to journalArticle