• 2119 Citations
  • 28 h-Index
20072020
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Research Output 2007 2019

  • 2119 Citations
  • 28 h-Index
  • 70 Article
  • 3 Comment/debate
  • 2 Review article
2019
1 Citation (Scopus)

Carbon monoxide releasing molecule-2 protects against particulate matter-induced lung inflammation by inhibiting TLR2 and 4/ROS/NLRP3 inflammasome activation

Lee, C. W., Chi, M. C., Hsu, L. F., Yang, C. M., Hsu, T. H., Chuang, C. C., Lin, W. N., Chu, P. M. & Lee, I. T., Aug 1 2019, In : Molecular Immunology. 112, p. 163-174 12 p.

Research output: Contribution to journalArticle

Inflammasomes
Toll-Like Receptor 2
Toll-Like Receptor 4
Particulate Matter
Carbon Monoxide
2 Citations (Scopus)

Participation of NADPH Oxidase-Related Reactive Oxygen Species in Leptin-Promoted Pulmonary Inflammation: Regulation of cPLA2α and COX-2 Expression

Hsu, P. S., Lin, C. M., Chang, J. F., Wu, C. S., Sia, K. C., Lee, I. T., Huang, K. Y. & Lin, W. N., Mar 1 2019, In : International Journal of Molecular Sciences. 20, 5, p. 1078 1078.

Research output: Contribution to journalArticle

Open Access
Cytosolic Phospholipases A2
NADPH Oxidase
oxidase
Cyclooxygenase 2
Leptin

Protective mechanisms of resveratrol derivatives against TNF-α-induced inflammatory responses in rat mesangial cells

Lee, I-T., Lin, C. F., Huang, Y. L., Chong, K. Y., Hsieh, M. F., Huang, T. H. & Cheng, C. Y., Jan 1 2019, In : Cytokine. 113, p. 380-392 13 p.

Research output: Contribution to journalArticle

Mesangial Cells
Rats
Tumor Necrosis Factor-alpha
Derivatives
Cytosolic Phospholipases A2

Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia

Chang, J. F., Yeh, J. C., Ho, C. T., Liu, S. H., Hsieh, C. Y., Wang, T. M., Chang, S. W., Lee, I. T., Huang, K. Y., Wang, J. Y. & Lin, W. N., Sep 6 2019, In : International Journal of Molecular Sciences. 20, 18

Research output: Contribution to journalArticle

Open Access
Cytosolic Phospholipases A2
Obese Mice
Endotoxemia
fibrosis
kidneys

Water-Soluble Fullerenol C60(OH)36 toward Effective Anti-Air Pollution Induced by Urban Particulate Matter in HaCaT Cell

Lee, C. W., Chi, M. C., Peng, K. T., Chiang, Y. C., Hsu, L. F., Yan, Y. L., Li, H. Y., Chen, M. C., Lee, I. T. & Lai, C. H., Aug 30 2019, In : International Journal of Molecular Sciences. 20, 17

Research output: Contribution to journalArticle

Open Access
air pollution
Particulate Matter
Air Pollution
Fullerenes
Air pollution
2018
1 Citation (Scopus)

Carbon monoxide ameliorates Staphylococcus aureus-elicited COX-2/IL-6/MMP-9-dependent human aortic endothelial cell migration and inflammatory responses

Tsai, M. H., Yang, C. M., Chang, K. T., Chuang, C. C., Lin, W. N., Jiang, R. S., Wu, C. H. & Lee, I. T., Nov 1 2018, In : Immunology Letters. 203, p. 40-49 10 p.

Research output: Contribution to journalArticle

Metalloproteases
Cyclooxygenase 2
Carbon Monoxide
Cell Movement
Staphylococcus aureus
2 Citations (Scopus)

Carbon monoxide releasing molecule-2 attenuates Pseudomonas aeruginosa-induced ROS-dependent ICAM-1 expression in human pulmonary alveolar epithelial cells

Lee, C. W., Wu, C. H., Chiang, Y. C., Chen, Y. L., Chang, K. T., Chuang, C. C. & Lee, I. T., Sep 1 2018, In : Redox Biology. 18, p. 93-103 11 p.

Research output: Contribution to journalArticle

Open Access
Alveolar Epithelial Cells
Intercellular Adhesion Molecule-1
Carbon Monoxide
Pseudomonas aeruginosa
Lung
1 Citation (Scopus)

Comparison of the incidence, clinical features and outcomes of invasive candidiasis in children and neonates

Hsu, J. F., Lai, M. Y., Lee, C. W., Chu, S. M., Wu, I. H., Huang, H. R., Lee, I-T., Chiang, M. C., Fu, R. H. & Tsai, M. H., Apr 24 2018, In : BMC Infectious Diseases. 18, 1, 194.

Research output: Contribution to journalArticle

Open Access
Invasive Candidiasis
Newborn Infant
Incidence
Confidence Intervals
Pediatrics

Corrigendum to “CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression” [Redox Biol. 12 (2017) 377–388]

Tsai, M. H., Lee, C. W., Hsu, L. F., Li, S. Y., Chiang, Y. C., Lee, M. H., Chen, C. H., Liang, H. F., How, J. M., Chang, P. J., Wu, C. M. & Lee, I. T., Jan 1 2018, (Accepted/In press) In : Redox Biology.

Research output: Contribution to journalArticle

Open Access
Cell Migration Inhibition
Matrix Metalloproteinase 9
Carbon Monoxide
Angiotensin II
Oxidation-Reduction

Erratum: Magnolol nanoparticles exhibit improved water solubility and suppress TNF-α-induced VCAM-1 expression in endothelial cells (Journal of Biomedical Nanotechnology (2017) 13:3 (225-268) DOI: 10.1166/jbn.2017.2342)

Lee, C. W., Hu, S. C. S., Yen, F. L., Hsu, L. F., Lee, I-T., Lin, Z. C., Tsai, M. H., Huang, C. L., Liang, C. J. & Chiang, Y. C., Dec 1 2018, In : Journal of Biomedical Nanotechnology. 14, 12, 1 p.

Research output: Contribution to journalComment/debate

Nanotechnology
Vascular Cell Adhesion Molecule-1
Endothelial cells
Taiwan
Patient rehabilitation
4 Citations (Scopus)

Extracts of Artocarpus communis induce mitochondria-associated apoptosis via pro-oxidative activity in human glioblastoma cells

Lee, C. W., Hsu, L. F., Lee, M. H., Lee, I. T., Liu, J. F., Chiang, Y. C. & Tsai, M. H., May 2 2018, In : Frontiers in Pharmacology. 9, MAY, 411.

Research output: Contribution to journalArticle

Open Access
Artocarpus
Glioblastoma
Human Activities
Mitochondria
Apoptosis
1 Citation (Scopus)

Infection with Staphylococcus aureus elicits COX-2/PGE 2 /IL-6/MMP-9-dependent aorta inflammation via the inhibition of intracellular ROS production

Tsai, M. H., Wu, C. H., Lin, W. N., Cheng, C. Y., Chuang, C. C., Chang, K. T., Jiang, R. S., Hsu, J. F. & Lee, I. T., Nov 1 2018, In : Biomedicine and Pharmacotherapy. 107, p. 889-900 12 p.

Research output: Contribution to journalArticle

Metalloproteases
Prostaglandins E
Aorta
Staphylococcus aureus
Interleukin-6
2 Citations (Scopus)

Resveratrol attenuates staphylococcus aureus-induced monocyte adhesion through downregulating pdgfr/ap-1 activation in human lung epithelial cells

Lee, I-T., Lin, C. C., Yang, C. C., Hsiao, L. D., Wu, M. Y. & Yang, C. M., Jan 1 2018, In : International Journal of Molecular Sciences. 19, 10, 3058.

Research output: Contribution to journalArticle

Open Access
Resveratrol
monocytes
staphylococcus
lungs
Staphylococcus aureus
2017
2 Citations (Scopus)

Aliskiren improves Ischemia- and oxygen glucose deprivation-induced cardiac injury through activation of autophagy and AMP-activated protein kinase

Chiang, M. H., Liang, C. J., Liu, C. W., Pan, B. J., Chen, W. P., Yang, Y. F., Lee, I-T., Tsai, J. S., Lee, C. W. & Chen, Y. L., Nov 14 2017, In : Frontiers in Pharmacology. 8, NOV, 819.

Research output: Contribution to journalArticle

Open Access
AMP-Activated Protein Kinases
Autophagy
Ischemia
Oxygen
Glucose
2 Citations (Scopus)

Breakthrough candidemia in children: Clinical and microbiological characteristics, therapeutic strategies and impact on outcomes

Lai, M. Y., Hsu, J. F., Chu, S. M., Wu, I. H., Huang, H. R., Lin, C. C., Lee, I-T., Chiang, M. C., Fu, R. H. & Tsai, M. H., Jun 1 2017, In : Future Microbiology. 12, 8, p. 695-705 11 p.

Research output: Contribution to journalArticle

Candidemia
Therapeutics
Candida
Fungemia
Fluconazole
8 Citations (Scopus)

CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression

Tsai, M. H., Lee, C. W., Hsu, L. F., Li, S. Y., Chiang, Y. C., Lee, M. H., Chen, C. H., Liang, H. F., How, J. M., Chang, P. J., Wu, C. M. & Lee, I-T., Aug 1 2017, In : Redox Biology. 12, p. 377-388 12 p.

Research output: Contribution to journalArticle

Open Access
Cell Migration Inhibition
Matrix Metalloproteinase 9
Carbon Monoxide
Angiotensin II
Smooth Muscle Myocytes
2 Citations (Scopus)

Magnolol nanoparticles exhibit improved water solubility and suppress TNF-α-induced VCAM-1 expression in endothelial cells

Lee, C. W., Hu, S. C. S., Yen, F. L., Hsu, L. F., Lee, I-T., Lin, Z. C., Tsai, M. H., Huang, C. L., Liang, C. J. & Chiang, Y. C., Mar 1 2017, In : Journal of Biomedical Nanotechnology. 13, 3, p. 255-268 14 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Cell adhesion
Endothelial cells
Nanoparticles
Solubility
18 Citations (Scopus)

Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: Evidence for an anti-inflammatory cascade mediated by the MIR-221/222/AMPK/p38/NF-7kappa;B pathway

Liu, C. W., Sung, H. C., Lin, S. R., Wu, C. W., Lee, C. W., Lee, I-T., Yang, Y. F., Yu, I. S., Lin, S. W., Chiang, M. H., Liang, C. J. & Chen, Y. L., Mar 24 2017, In : Scientific Reports. 7, 44689.

Research output: Contribution to journalArticle

Open Access
Adhesiveness
AMP-Activated Protein Kinases
Intercellular Adhesion Molecule-1
Monocytes
Anti-Inflammatory Agents
17 Citations (Scopus)

Resveratrol inhibits urban particulate matter-induced COX-2/PGE2 release in human fibroblast-like synoviocytes via the inhibition of activation of NADPH oxidase/ROS/NF-κB

Tsai, M. H., Hsu, L. F., Lee, C. W., Chiang, Y. C., Lee, M. H., How, J. M., Wu, C. M., Huang, C. L. & Lee, I-T., Jul 1 2017, In : International Journal of Biochemistry and Cell Biology. 88, p. 113-123 11 p.

Research output: Contribution to journalArticle

Particulate Matter
NADPH Oxidase
Cyclooxygenase 2
Fibroblasts
Dinoprostone
2016
14 Citations (Scopus)

Anti-melanoma activity of Bupleurum chinense, Bupleurum kaoi and nanoparticle formulation of their major bioactive compound saikosaponin-d

Hu, S. C. S., Lee, I-T., Yen, M. H., Lin, C. C., Lee, C. W. & Yen, F. L., Feb 17 2016, In : Journal of Ethnopharmacology. 179, p. 432-442 11 p.

Research output: Contribution to journalArticle

Bupleurum
Nanoparticles
Melanoma
Solubility
Particle Size
6 Citations (Scopus)

Clinical and molecular characteristics of neonatal extended-spectrum β-lactamase-producing gram-negative bacteremia: A 12-year case-control-control study of a referral center in Taiwan

Tsai, M. H., Lee, I-T., Chu, S. M., Lien, R., Huang, H. R., Chiang, M. C., Fu, R. H., Hsu, J. F. & Huang, Y. C., Aug 1 2016, In : PLoS One. 11, 8, e0159744.

Research output: Contribution to journalArticle

Open Access
bacteremia
compound A 12
Bacteremia
Taiwan
Referral and Consultation
9 Citations (Scopus)

Eupafolin ameliorates COX-2 expression and PGE 2 production in particulate pollutants-exposed human keratinocytes through ROS/MAPKs pathways

Lee, C. W., Lin, Z. C., Hsu, L. F., Fang, J. Y., Chiang, Y. C., Tsai, M. H., Lee, M. H., Li, S. Y., Hu, S. C. S., Lee, I-T. & Yen, F. L., Aug 2 2016, In : Journal of Ethnopharmacology. 189, p. 300-309 10 p.

Research output: Contribution to journalArticle

Particulate Matter
Cyclooxygenase 2
Prostaglandins E
Keratinocytes
Reactive Oxygen Species
4 Citations (Scopus)

Infectious complications and morbidities after neonatal bloodstream infections: An observational cohort study

Tsai, M. H., Lee, C. W., Chu, S. M., Lee, I-T., Lien, R., Huang, H. R., Chiang, M. C., Fu, R. H., Hsu, J. F. & Huang, Y. C., Jan 1 2016, In : Medicine (United States). 95, 11, e3078.

Research output: Contribution to journalArticle

Observational Studies
Cohort Studies
Morbidity
Infection
Septic Shock
30 Citations (Scopus)

Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells

Cho, R. L., Yang, C. C., Lee, I-T., Lin, C. C., Chi, P. L., Hsiao, L. D. & Yang, C. M., Apr 1 2016, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 310, 7, p. L639-L657

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
NADPH Oxidase
Intercellular Adhesion Molecule-1
Lipopolysaccharides
Reactive Oxygen Species
43 Citations (Scopus)

Urban particulate matter down-regulates filaggrin via COX2 expression/PGE2 production leading to skin barrier dysfunction

Lee, C. W., Lin, Z. C., Hu, S. C. S., Chiang, Y. C., Hsu, L. F., Lin, Y. C., Lee, I-T., Tsai, M. H. & Fang, J. Y., Jun 17 2016, In : Scientific Reports. 6, 27995.

Research output: Contribution to journalArticle

Open Access
Particulate Matter
Cyclooxygenase 2
Dinoprostone
Down-Regulation
Aryl Hydrocarbon Receptors
2015
17 Citations (Scopus)

c-Src-dependent transactivation of EGFR mediates CORM-2-induced HO-1 expression in human tracheal smooth muscle cells

Yang, C. M., Lin, C. C., Lee, I-T., Hsu, C. K., Tai, Y. C., Hsieh, H. L., Chi, P. L. & Hsiao, L. D., Oct 1 2015, In : Journal of Cellular Physiology. 230, 10, p. 2351-2361 11 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Carbon Monoxide
Transcriptional Activation
Smooth Muscle Myocytes
Muscle
11 Citations (Scopus)

Incidence, prevalence, and medical expenditures of classical amyotrophic lateral sclerosis in Taiwan, 1999-2008

Tsai, C. P., Wang, K. C., Hwang, C. S., Lee, I-T. & Lee, C. T. C., Jul 1 2015, In : Journal of the Formosan Medical Association. 114, 7, p. 612-619 8 p.

Research output: Contribution to journalArticle

Open Access
Amyotrophic Lateral Sclerosis
Health Expenditures
Taiwan
Incidence
Riluzole
31 Citations (Scopus)

Sphingosine-1-phosphate mediates COX-2 expression and PGE2/IL-6 secretion via c-Src-Dependent AP-1 activation

Hsu, C. K., Lee, I-T., Lin, C. C., Hsiao, L. D. & Yang, C. M., Mar 1 2015, In : Journal of Cellular Physiology. 230, 3, p. 702-715 14 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Cyclooxygenase 2
Dinoprostone
Interleukin-6
Chemical activation
16 Citations (Scopus)

Sphingosine-1-phosphate mediates ICAM-1-dependent monocyte adhesion through p38 MAPK and p42/p44 MAPK-dependent akt activation

Lin, C. C., Lee, I-T., Hsu, C. H., Hsu, C. K., Chi, P. L., Hsiao, L. D. & Yang, C. M., Mar 3 2015, In : PLoS One. 10, 3, e0118473.

Research output: Contribution to journalArticle

Open Access
sphingosine
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
p38 Mitogen-Activated Protein Kinases
Intercellular Adhesion Molecule-1
21 Citations (Scopus)

TNF-α mediates PKCδ/JNK1/2/c-Jun-dependent monocyte adhesion via ICAM-1 induction in human retinal pigment epithelial cells

Lee, I-T., Liu, S. W., Chi, P. L., Lin, C. C., Hsiao, L. D. & Yang, C. M., Feb 12 2015, In : PLoS One. 10, 2, e0117911.

Research output: Contribution to journalArticle

Open Access
Retinal Pigments
Intercellular Adhesion Molecule-1
monocytes
adhesion
Monocytes
2014
18 Citations (Scopus)

c-Src/Jak2/PDGFR/PKCδ-dependent MMP-9 induction is required for thrombin-stimulated rat brain astrocytes migration

Lin, C. C., Lee, I-T., Chi, P. L., Hsieh, H. L., Cheng, S. E., Hsiao, L. D., Liu, C. J. & Yang, C. M., Jan 1 2014, In : Molecular Neurobiology. 49, 2, p. 658-672 15 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Thrombin
Astrocytes
Brain
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
15 Citations (Scopus)

C-Src-dependent transactivation of PDGFR contributes to TNF-α-induced MMP-9 expression and functional impairment in osteoblasts

Tsai, C. L., Chen, W. C., Lee, I-T., Chi, P. L., Cheng, S. E. & Yang, C. M., Mar 1 2014, In : Bone. 60, p. 186-197 12 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Osteoblasts
Transcriptional Activation
Tumor Necrosis Factor-alpha
Transcription Factor AP-1

Erratum: Lung inflammation caused by adenosine-5′-triphosphate is mediated via Ca2+/PKCs-dependent COX-2/PGE2 induction (Int. J. Biochem. Cell Biol. (2013) 45 (1657-1668))

Lee, I-T., Lin, C. C., Lin, W. N., Wu, W. L., Hsiao, L. D. & Yang, C. M., Jan 1 2014, In : International Journal of Biochemistry and Cell Biology. 46, 1, p. 162-163 2 p.

Research output: Contribution to journalComment/debate

Dinoprostone
Adenosine
Pneumonia
Adenosine Triphosphate
triphosphoric acid
19 Citations (Scopus)

HO-1 induction by CO-RM2 attenuates TNF- α -induced cytosolic phospholipase A2 expression via inhibition of PKC α -dependent NADPH oxidase/ROS and NF- B

Chi, P. L., Liu, C. J., Lee, I-T., Chen, Y. W., Hsiao, L. D. & Yang, C. M., Mar 5 2014, In : Mediators of Inflammation. 2014, 279171.

Research output: Contribution to journalArticle

Open Access
Cytosolic Phospholipases A2
Heme Oxygenase-1
NADPH Oxidase
Carbon Monoxide
Rheumatoid Arthritis
10 Citations (Scopus)
Smooth Muscle Myocytes
Cytokines
Antigens
Small Interfering RNA
Transfection
13 Citations (Scopus)

Resveratrol inhibits Staphylococcus aureus-induced TLR2/MyD88/NF-κB-dependent VCAM-1 expression in human lung epithelial cells.

Lee, I-T., Lin, C. C., Hsu, C. K., Wu, M. Y., Cho, R. L. & Yang, C. M., Jan 1 2014, In : Clinical science (London, England : 1979). 127, 6, p. 375-390 16 p.

Research output: Contribution to journalArticle

Myeloid Differentiation Factor 88
Toll-Like Receptor 2
Vascular Cell Adhesion Molecule-1
Staphylococcus aureus
Epithelial Cells
10 Citations (Scopus)

Thrombin induces ICAM-1 expression in human lung epithelial cells via c-Src/PDGFR/PI3K/ Akt-dependent NF-κB/p300 activation

Cheng, S. E., Lee, I-T., Lin, C. C., Hsiao, L. D. & Yang, C. M., Jan 1 2014, In : Clinical Science. 127, 3, p. 171-183 13 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Complement Factor B
Intercellular Adhesion Molecule-1
Thrombin
Phosphotransferases
12 Citations (Scopus)

TNF-α induces cytosolic phospholipase A2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells

Yang, C. M., Lee, I-T., Chi, P. L., Cheng, S. E., Hsiao, L. D. & Hsu, C. K., Mar 15 2014, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 306, 6

Research output: Contribution to journalArticle

Cytosolic Phospholipases A2
Platelet-Derived Growth Factor Receptors
Tumor Necrosis Factor-alpha
Epithelial Cells
Lung
2013
33 Citations (Scopus)

ATP Mediates NADPH Oxidase/ROS Generation and COX-2/PGE2 Expression in A549 Cells: Role of P2 Receptor-Dependent STAT3 Activation

Cheng, S. E., Lee, I-T., Lin, C. C., Wu, W. L., Hsiao, L. D. & Yang, C. M., Jan 17 2013, In : PLoS One. 8, 1, e54125.

Research output: Contribution to journalArticle

Open Access
NADPH Oxidase
prostaglandin synthase
Cyclooxygenase 2
Dinoprostone
prostaglandins
10 Citations (Scopus)

ATP stimulates PGE2/cyclin D1-dependent VSMCs proliferation via STAT3 activation: Role of PKCs-dependent NADPH oxidase/ROS generation

Lee, I-T., Lin, C. C., Wang, C. H., Cherng, W. J., Wang, J. S. & Yang, C. M., Apr 1 2013, In : Biochemical Pharmacology. 85, 7, p. 954-964 11 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Cyclin D1
Cell proliferation
Cyclooxygenase 2
Vascular Smooth Muscle
27 Citations (Scopus)

C-Src-dependent MAPKs/AP-1 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells

Yang, C. M., Lee, I-T., Lin, C. C., Wang, C. H., Cherng, W. J. & Hsiao, L. D., Apr 15 2013, In : Biochemical Pharmacology. 85, 8, p. 1115-1123 9 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Transcription Factor AP-1
Rats
Phosphorylation
Chemical activation
41 Citations (Scopus)

IL-1β Promotes Corneal Epithelial Cell Migration by Increasing MMP-9 Expression through NF-κB- and AP-1-Dependent Pathways

Tseng, H. C., Lee, I-T., Lin, C. C., Chi, P. L., Cheng, S. E., Shih, R. H., Hsiao, L. D. & Yang, C. M., Mar 7 2013, In : PLoS One. 8, 3, e57955.

Research output: Contribution to journalArticle

Open Access
gelatinase B
Matrix Metalloproteinase 9
Transcription Factor AP-1
interleukin-1
Interleukin-1
124 Citations (Scopus)

Inflammatory signalings involved in airway and pulmonary diseases

Lee, I-T. & Yang, C. M., May 13 2013, In : Mediators of Inflammation. 2013, 791231.

Research output: Contribution to journalReview article

Open Access
Lung Diseases
Chemokines
Pneumonia
Proteins
Cytosolic Phospholipases A2
14 Citations (Scopus)

Lung inflammation caused by adenosine-5'-triphosphate is mediatedvia Ca2+/PKCs-dependent COX-2/PGE2induction

Leea, I-T., Lin, C. C., Lin, W. N., Wu, W. L., Hsiao, L. D. & Yang, C. M., Jan 1 2013, In : International Journal of Biochemistry and Cell Biology. 45, 8, p. 1657-1668 12 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Adenosine
Pneumonia
Adenosine Triphosphate
Prostaglandins E
20 Citations (Scopus)

NADPH oxidase/ROS-dependent PYK2 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells

Yang, C. M., Lee, I-T., Hsu, R. C., Chi, P. L. & Hsiao, L. D., Oct 15 2013, In : Toxicology and Applied Pharmacology. 272, 2, p. 431-442 12 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Matrix Metalloproteinase 9
Rats
Acetylcysteine
Chemical activation
48 Citations (Scopus)

Protective effects of (-)-epigallocatechin-3-gallate against TNF-α-induced lung inflammation via ROS-dependent ICAM-1 inhibition

Lee, I-T., Lin, C. C., Lee, C. Y., Hsieh, P. W. & Yang, C. M., Jan 1 2013, In : Journal of Nutritional Biochemistry. 24, 1, p. 124-136 13 p.

Research output: Contribution to journalArticle

Intercellular Adhesion Molecule-1
Reactive Oxygen Species
Pneumonia
Heme Oxygenase-1
Tumor Necrosis Factor-alpha
42 Citations (Scopus)

Riluzole and prognostic factors in amyotrophic lateral sclerosis long-term and short-term survival: A Population-based study of 1149 cases in Taiwan

Lee, C. T. C., Chiu, Y. W., Wang, K. C., Hwang, C. S., Lin, K. H., Lee, I. T. & Tsai, C. P., Mar 12 2013, In : Journal of Epidemiology. 23, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

Open Access
Riluzole
Amyotrophic Lateral Sclerosis
Taiwan
Tracheotomy
Survival
17 Citations (Scopus)

Thrombin mediates migration of rat brain astrocytes via PLC, Ca 2+, CaMKII, PKCα, and AP-1-dependent matrix metalloproteinase-9 expression

Lin, C. C., Lee, I-T., Wu, W. B., Liu, C. J., Hsieh, H. L., Hsiao, L. D., Yang, C. C. & Yang, C. M., Jan 1 2013, In : Molecular Neurobiology. 48, 3, p. 616-630 15 p.

Research output: Contribution to journalReview article

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Matrix Metalloproteinase 9
Transcription Factor AP-1
Thrombin
Astrocytes
27 Citations (Scopus)

TNF-α Induces Cytosolic Phospholipase A2 Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation

Lee, I-T., Lin, C. C., Cheng, S. E., Hsiao, L. D., Hsiao, Y. C. & Yang, C. M., Sep 19 2013, In : PLoS One. 8, 9, e72783.

Research output: Contribution to journalArticle

Open Access
Cytosolic Phospholipases A2
phospholipase A2
tumor necrosis factors
Transcription Factor AP-1
p38 Mitogen-Activated Protein Kinases
2012
17 Citations (Scopus)
NADPH Oxidase
Cyclooxygenase 2
Prostaglandins E
Hydrogen Peroxide
Adenosine Triphosphate